检索结果-南通市图书馆

The integrative analysis of microRNA and mRNA expression in Apis mellifera following maze-based visual pattern learning

引用

Insect Science 2014年第5期21卷 619-636页

作者： qiu-hong qin Zi-Long Wang Liu-qing Tian Hai-Yan Gan Shao-Wu Zhang Zhi-Jiang Zeng Honeybee Research Institute Jiangxi Agricultural University Nanchang China ARC Center of Excellence in Vision Science Research School of Biology The Australian National University Canberra ACT Australia

The honeybee （Apis mellifera） is a social insect with strong sensory capacity and diverse behavioral repertoire and is recognized as a good model organism for studying the neurobiological basis of learning and memory. In this study, we analyzed the changes in microRNA （miRNA） and messenger RNA （mRNA） following maze-based visual learning using next-generation small RNA sequencing and Solexa/lllumina Digital Gene Expression tag profiling （DGE）. For small RNA sequencing, we obtained 13 367 770 and 13 132 655 clean tags from the maze and control groups, respectively. A total of 40 differentially expressed known miRNAs were detected between these two samples, and all of them were up-regulated in the maze group compared to the control group. For DGE, 5 681 320 and 5 939 855 clean tags were detected from the maze and control groups, respectively. There were a total of 388 differentially expressed genes between these two samples, with 45 genes up-regulated and 343 genes down-regulated in the maze group, compared to the control group. Additionally, the expression levels of 10 differentially expressed genes were confirmed by quantitative reverse transcription polymerase chain reaction （qRT-PCR） and the expression trends of eight of them were consistent with the DGE result, although the degree of change was lower in amplitude. The integrative analysis of miRNA and mRNA expression showed that, among the 40 differentially expressed known miRNAs and 388 differentially expressed genes, 60 pairs of miRNA/mRNA were identified as co-expressed in our present study. These results suggest that both miRNA and mRNA may play a pivotal role in the process of learning and memory in honeybees. Our sequencing data provide comprehensive miRNA and gene expression information for maze-based visual learning, which will facilitate understanding of the molecular mechanisms of honeybee learning and memory.

关键词： Apis mellifera Y-maze learning and memory microRNA DGE differential expression

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cross-sectional study of congenital heart disease among Tibetan children aged from 4 to 18 years at different altitudes in qinghai Province

引用

Chinese Medical Journal 2008年第24期121卷 2469-2472页

作者： CHEN qiu-hong WANG Xiao-qin QI Sheng-gui Central Laboratory Qinghai Cardiovascular Diseases Vocational Hospital Xining Qinghai 810012 China

Background Congenital heart disease （CHD） is a common heart condition which does considerable harm to the health of children and adolescents. CHD epidemiological characteristics of Tibetan children whose ages ranged from 4 to 18 years were investigated in qinghai Province. Methods A total of 32 578 Tibetan children, living at altitudes of 2535 m, 3600 m and 4200 m, were examined using a three-stage protocol： prescreening, rechecking and diagnosis using a color Doppler. The distribution of CHD at different altitudes was analyzed together with differences in occurrence according to age and gender. Results A total of 235 CHD cases were discovered. The total prevalence of CHD was 7.21‰. Prevalence of CHD has been shown to increase along with increase in altitude with 5.45‰ at an altitude of 2535 m, 6.80‰ at 3600 m and 9.79‰ at 4200 m. There were no statistically significant differences between the prevalence at 2535 m and 3600 m （Х^2=1.594, P 〉0.05）. However, there was a significant difference between the prevalence at 2535 m and 4200 m （Х^2=7.002, P 〈0.01）. Also, apparent differences existed between the prevalence at 3600 m and at 4200 m （Х^2=5.540, P 〈0.05）. There was no statistically significant difference in prevalence according to age at an altitude of 2535 m, but the rate of CHD increased significantly along with increasing age at 3600 m and 4200 m. The total prevalence ratio of children aged from 16 to 18 years was significantly higher than that of children from 4 to 7, and from 8 to 12 with Х^2 values of 10.79 （P 〈0.005）, and 5.60 （P 〈0.05） respectively. Within the constituent ratio of CHD, the prevalence of atrial septal defect （ASD） was the highest at 39.10%, followed by the prevalence of ventricular septal defect （VSD） at 32.8% and patent ductus arteriosus （PDA） at 24.7%. Furthermore the proportion of the four categories of CHD varied at different altitude levels： at 2535 m, of those diagnosed with CHD, the prevalence rate of VSD was the highest at 43.5%, at

关键词： congenital heart disease epidemiological monitoring prevalence Tibetan

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Electrocatalytic cleavage of a lignin β-O-4 model compound and coupling with nitrogen-containing aromatics using Prussian blue analogue-derived nickel–cobalt spinel

引用

Journal of Energy Chemistry 2025年第1期100卷 628-636页

作者： Yi Qi Xueying Chen Bowen Liu Xuliang Lin Xueqing qiu Yanlin qin Guangdong Provincial Key Laboratory of Plant Resources Biorefinery School of Chemical Engineering and Light Industry Guangdong University of Technology Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center Guangdong Basic Research Center of Excellence for Ecological Security and Green Development Guangdong University of Technology

Electrochemical conversion of lignin for the production of high-value heterocyclic aromatic compounds has great *** demonstrate the targeted synthesis and cation modulation of NiCo2O4spinel nanoboxes,synthesized via cation exchange and calcination *** catalysts exhibit excellent efficacy in the electrocatalytic conversion of lignin model compounds,specifically 2-phenoxy-1-phenylethanol,into nitrogen-containing aromatics,achieving high conversion rates and *** catalysts were synthesized via a cation exchange and calcination oxidation process,using Prussian blue nanocubes as *** porous architecture and polymetallic composition of the NiCo2O4spinel demonstrated superior performance in electrocatalytic oxidative coupling,achieving a 99.2 wt%conversion rate of the 2-phenoxy-1-phenylethanol with selectivities of 37.5 wt%for quinoline derivatives and 31.5 wt%for *** innovations include the development of a sustainable one-pot synthesis method for quinoline derivatives,the elucidation of a multistage reaction pathway involving CAO bond cleavage,hydroxyaldol condensation,and CAN bond formation,and a deeper mechanistic understanding derived from DFT *** work establishes a new strategy for lignin valorization,offering a sustainable route to produce high-value nitrogen-containing aromatics from renewable biomass under mild conditions,without the need for additional reagents.

关键词： Spinel Biomass valorization Electrocatalysis Lignin oxidation Coupling

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

近25年国际体育教育动态演变研究的可视化分析

引用

山东体育学院学报 2017年第3期33卷 94-99页

作者：何秋鸿李勇勤重庆交通大学重庆400074 北京体育大学北京100084

以Web of ScienceTM核心合集收录的1991-2015年有关体育教育为主题的2 315篇文献题录数据为研究对象,运用文献资料、文献计量等方法,并利用Cite Space III分析软件,对体育教育研究文献的分布时间、国家与地区、核心作者及研究的热点等... 详细信息

以Web of ScienceTM核心合集收录的1991-2015年有关体育教育为主题的2 315篇文献题录数据为研究对象,运用文献资料、文献计量等方法,并利用Cite Space III分析软件,对体育教育研究文献的分布时间、国家与地区、核心作者及研究的热点等进行可视化分析,力图揭示国际体育教育研究的动态演变。研究表明:国际体育教育研究文献呈多项式函数增长趋势;体育教育研究成果的产出分布极不平衡,主要集中在欧美等发达国家;学科分布主要集中于教育与教育研究、运动科学和社会科学;核心作者主要为美国、澳大利亚、英国和爱尔兰等国的学者。研究的热点主要集中在儿童和青少年的体育教育、体育教育计划、课程设置、体育技能、体育教师。

关键词：体育教育可视化动态演变研究热点

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

机采血小板红细胞溢出(冲红)原因及干预措施

引用

医药论坛杂志 2019年第5期40卷 60-62页

作者：邱红钦张戈河南省红十字血液中心

目的探讨机采血小板红采集过程中细胞溢出的原因,并进行干预,减少红细胞溢出,提高血小板质量。方法将出现红细胞溢出现象的33名献血者作为溢出组,随机抽取同期33名未发生红细胞溢出现象的献血者作为对照组,分别抽取两组静脉血,对红细胞... 详细信息

目的探讨机采血小板红采集过程中细胞溢出的原因,并进行干预,减少红细胞溢出,提高血小板质量。方法将出现红细胞溢出现象的33名献血者作为溢出组,随机抽取同期33名未发生红细胞溢出现象的献血者作为对照组,分别抽取两组静脉血,对红细胞、血小板诸参数进行比较,并根据结果进行干预。结果比较有红细胞溢出的机采血小板献血者与未出现红细胞溢出的机采血小板献血者红细胞平均体积(MCV)、平均血红蛋白(MCH)及平均血红蛋白浓度(MCHC)的检测结果,其差异有统计学意义(P0.05)。采取干预措施后,机采血小板发生红细胞溢出现象由2.1‰降低至0.7‰。结论献血者血液MCV、MCH及MCHC三项参数结果偏低可造成机采血小板采集过程中红细胞溢出,乳糜血、初次捐献血小板精神紧张及设备因素均可导致红细胞溢出。注重对机采血小板捐献者的筛选,具有良好的静脉穿刺技术,采集过程中要保证良好的采集流速,同时要加大机采血小板献血知识的宣传等措施,是减少红细胞溢出的重要方法。

关键词：献血者机采血小板红细胞溢出

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

采供血过程中不合格血液原因分析

引用

河南医学研究 2019年第6期28卷 988-990页

作者：邱红钦温涛张戈河南省红十字血液中心河南郑州450012

目的分析不合格血液分布情况及原因,采取有效措施避免或减少血液资源浪费。方法回顾性分析2017年1—12月郑州地区在河南省红十字血液中心进行无偿献血的213 997例(382 936 U)血液样品,最终成分血总制备量为1 259 712 U。根据国家标准和... 详细信息

目的分析不合格血液分布情况及原因,采取有效措施避免或减少血液资源浪费。方法回顾性分析2017年1—12月郑州地区在河南省红十字血液中心进行无偿献血的213 997例(382 936 U)血液样品,最终成分血总制备量为1 259 712 U。根据国家标准和相关法规要求,对血液进行检测、分离、制备,筛查出不合格血液,同时对医疗机构退回的血液进行分析。结果无偿献血血液总体不合格率为3.23%(40 804/1 259 712),其中检验不合格血液占1.25%(15 784/1 259 712),非检验不合格血液占1.77%(22 304/1 259 712),医院退血占0.21%(2 716/1 259 712)。ALT水平高、脂血、血袋破损是3类不合格血液的主要原因。结论应针对不同的血液报废原因,采取针对性的措施规范采供血过程的各类操作,同时加强无偿献血的宣传教育,从源头减少不合格血液的产生。

关键词：采供血血液不合格检验

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recent progress in constructing fluorinated solid-electrolyte interphases for stable lithium metal anodes

引用

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 270-291页

作者： Di Zhang Pengfei Lv Wei qin Xin He Yuanhua He Civil Aircraft Fire Science and Safety Engineering Key Laboratory of Sichuan Province College of Civil Aviation Safety EngineeringCivil Aviation Flight University of ChinaGuanghan 618307China School of Chemical Engineering Sichuan UniversityChengdu 610065China

Lithium metal batteries(LMBs)are emerging as a promising energy storage solution owing to their high energy density and specific ***,the non-uniform plating of lithium and the potential rupture of the solid-electrolyte interphase(SEI)during extended cycling use may result in dendrite growth,which can penetrate the separator and pose significant short-circuit *** a stable SEI is essential for the long-term operation of the ***-rich SEI has garnered significant attention for its ability to effectively passivate electrodes,regulate lithium deposition,and inhibit electrolyte *** the structural components and preparation methods of existing fluorinated SEI is crucial for optimizing lithium metal anode *** paper reviews the research on optimizing LiF passivation interfaces to protect lithium metal *** focuses on four types of compositions in fluorinated SEI that work synergistically to enhance SEI *** instance,combining compounds with LiF can further enhance the mechanical strength and ionic conductivity of the *** metals with LiF significantly improves electrochemical performance at the SEI/anode interface,with a necessary focus on reducing electron tunneling ***,incorporating polymers with LiF offers balanced improvements in interfacial toughness and ionic conductivity,though maintaining structural stability over long cycles remains a critical area for future *** alloys combined with LiF increase surface energy and lithium affinity,challenges such as dendrite growth and volume expansion *** summary,this paper emphasizes the crucial role of interfacial structures in LMBs and offers comprehensive guidance for future design and development efforts in battery technology.

关键词： LiF lithium metal anodes solid-electrolyte interphase interface cycling stability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

经阴道彩色多普勒超声在子宫肌瘤中的诊断价值

引用

影像技术 2019年第3期31卷 19-21页

作者：邱钦红谢彩珍广西玉林市陆川县人民医院功能科广西537700

目的:观察在子宫肌瘤中应用阴道影像学检查方法的诊断价值。方法:纳入2018年1月至2018年6月子宫肌瘤病人1040例,依照随机排列方法,分为对照组(n=520)和观察组(n=520),对照组实施常规超声影像学诊断,观察组实施经阴道彩色多普勒超声(TVC... 详细信息

目的:观察在子宫肌瘤中应用阴道影像学检查方法的诊断价值。方法:纳入2018年1月至2018年6月子宫肌瘤病人1040例,依照随机排列方法,分为对照组(n=520)和观察组(n=520),对照组实施常规超声影像学诊断,观察组实施经阴道彩色多普勒超声(TVCDS)诊断,对比两组病人使用不同检查方法后的确诊情况。结果:在子宫肌瘤中采用彩色多普勒超声影像学检查,观察组临床确诊率明显优于对照组,结果具有统计学意义(P<0.05)。结论:TVCDS影像学检查对子宫肌瘤病人诊断价值较高,临床具有广泛使用意义。

关键词：子宫肌瘤经阴道彩色多普勒诊断价值影像学检查

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

引用

World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin Zhou Dan Ma Yi-Xiang He Jing Jin hong-Lian Wang Yun-Feng Wang Fan Yang Jian-qin Liu Jie Chen Zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

突发公共卫生事件时采供血服务体系应急策略

引用

河南医学研究 2020年第30期29卷 5569-5571页

作者：司天宁邱红钦温涛河南省红十字血液中心河南郑州450052

目的以新型冠状病毒肺炎疫情为例探讨突发公共卫生事件时采供血服务体系应急策略。方法通过预约献血、加大宣传招募力度、上门采血、加大出车频次、延长出车时间等措施提升采血量;增加疫情期间征询体检表,告知每位献血者若献血后出现发... 详细信息

目的以新型冠状病毒肺炎疫情为例探讨突发公共卫生事件时采供血服务体系应急策略。方法通过预约献血、加大宣传招募力度、上门采血、加大出车频次、延长出车时间等措施提升采血量;增加疫情期间征询体检表,告知每位献血者若献血后出现发热等症状,或有与郑州市确诊病例同时间同空间接触,需及时告知,待血液隔离储存14 d后联系献血者确认情况,对此血液安全进行评估,防止因输血感染新型冠状病毒肺炎病例的发生。结果和往年同期相比,采血量仅下降23.1%,及时保障了本省临床用血和武汉临床用血。结论采供血机构在应对突发公共卫生事件时应科学制定应急预案,采取合理有效的应对策略,持续提高应急处理能力,安全、规范地开展采供血工作,保障血液供应。

关键词：突发公共卫生事件采供血机构策略

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：