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Myeloid sarcoma with maxillary gingival swell

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World Journal of Clinical Cases 2024年第19期12卷 3985-3994页

作者： Shu-han Li Cai-Xiu Yang Xiao-Ming Xing Xiang-Ru Gao Zhao-Yu Lu qiu-Xia Ji Department of Periodontology The Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina Department of Periodontology School of Stomatology of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Pathology The Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina

BACKGROUND Myeloid sarcoma(MS),also referred to as granulocytic sarcoma or chloroma,is a rare type of extramedullary malignant *** comprises primitive granulocytic precursor cells that play a key role in the early stages of white blood cell ***,the occurrence of this tumor in the gingiva is *** SUMMARY The present study reported the case of MS with gingival swelling in the maxillary region,with aleukemic presentation in a 32-year-old male *** two courses of chemotherapy,computed tomography of the region demonstrated complete clearance of the *** the 12-month follow-up appointment,the patient was in a stable condition with the absence of *** etiology,clinical features,diagnosis,and relevant treatment of MS are discussed in the present *** Diagnosis of MS may be confirmed following histological and immunohistochemical examinations.

关键词： Acute myeloid leukemia Biopsy Gingival Myeloid sarcoma Immunohistochemistry Case report

TiO_(2)@PT光催化剂的构建及其光催化降解甲苯性能

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中国环境科学 2024年第1期44卷 65-71页

作者：朱秋莲王秉好卢晗锋浙江工业大学化学工程学院环境污染控制创新团队浙江杭州310014

以对苯二胺和对苯二甲醛为原料,在TiO_(2)表面原位缩合得到二氧化钛复合对苯二胺缩对苯二甲醛聚合物催化剂(TiO_(2)@PT),研究催化剂降解甲苯的光催化性能.利用扫描电子显微镜(SEM),比表面积测试(BET),红外光谱(FT-IR),光致发光光谱(PL)... 详细信息

以对苯二胺和对苯二甲醛为原料,在TiO_(2)表面原位缩合得到二氧化钛复合对苯二胺缩对苯二甲醛聚合物催化剂(TiO_(2)@PT),研究催化剂降解甲苯的光催化性能.利用扫描电子显微镜(SEM),比表面积测试(BET),红外光谱(FT-IR),光致发光光谱(PL),紫外吸收光谱(UV-Vis)以及瞬态光电流测试(TPC)表征手段确定了催化剂的结构形貌及光学特性.通过催化降解甲苯废气的活性测试,发现在365nm紫外光的照射下,TiO_(2)@PT复合材料对气相甲苯的降解效果良好.此外,研究了在不同聚合物包裹比例,催化剂用量,甲苯浓度,温度等条件下,TiO_(2)@PT对甲苯的降解效果,结果表明0.1g TiO_(2)@1%PT在100W紫外灯照射下对1000×10^(-6)甲苯的降解率最高,可以达到26.41%,对应的反应速率为1177.89µmol/(g·h).

关键词：光催化技术甲苯降解二氧化钛有机聚合物复合材料

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临床护士医学叙事能力现状及影响因素分析

中国医学伦理学 2024年第5期37卷 578-585页

作者：李婷刘倩王艳韩菊西安交通大学第一附属医院公共卫生中心陕西西安710061 西安交通大学第一附属医院内分泌代谢科陕西西安710061 安康市中医医院内分泌科陕西安康725000 西安交通大学第一附属医院陕西西安710061

目的了解临床护士医学叙事能力现状并分析其影响因素,为提升护士医学叙事能力提供理论依据。方法采用便利抽样法,于2023年5月30日至6月30日选取陕西省内不同医院的1511名护士为研究对象,采用一般资料调查表、医学叙事能力量表对护士医... 详细信息

目的了解临床护士医学叙事能力现状并分析其影响因素,为提升护士医学叙事能力提供理论依据。方法采用便利抽样法,于2023年5月30日至6月30日选取陕西省内不同医院的1511名护士为研究对象,采用一般资料调查表、医学叙事能力量表对护士医学叙事能力现状进行调查并分析影响因素。结果临床护士医学叙事能力总分为(152.75±23.98)。多重线性回归显示,在临床中对患者实施人文关怀的情况,对叙事医学的熟悉程度、对叙事护理的看法、是否有叙事相关实践经历、对护理工作的满意度、就职科室为妇科科室是护士医学叙事能力的影响因素。结论临床护士医学叙事能力处于中等偏上水平,医院管理者应根据其影响因素,给予针对性的培训,关爱护士心理健康,减轻护士职业压力,提高护士的工作满意度,以进一步提升其医学叙事能力水平,助力专业成长。

关键词：临床护士叙事医学医学叙事能力医学叙事经历叙事护理

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Molecular dynamics study of primary radiation damage in TiVTa concentrated solid-solution alloy

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Chinese Physics B 2024年第3期33卷 530-535页

作者：赵永鹏豆艳坤贺新福曹晗王林枫邓辉球杨文 Reactor Engineering Technology Research Division China Institute of Atomic EnergyBeijing 102413China School of Physics and Electronics Hunan UniversityChangsha 410082China

The primary radiation damage in pure V and TiVTa concentrated solid-solution alloy(CSA)was studied using a molecular dynamics *** have performed displacement cascade simulations to explore the generation and evolution behavior of irradiation *** results demonstrate that the defect accumulation and agglomeration in TiVTa CSA are significantly suppressed compared to pure *** peak value of Frenkel pairs during cascade collisions in TiVTa CSA is much higher than that in pure V due to the lower formation energy of point ***,the longer lifetime of the thermal spike relaxation and slow energy dissipation capability of TiVTa CSA can facilitate the recombination of point *** defect agglomeration rate in TiVTa CSA is much lower due to the lower binding energy of interstitial clusters and reduced interstitial ***,the occurrence probability of dislocation loops in TiVTa CSA is lower than that in pure *** reduction in primary radiation damage may enhance the radiation resistance of TiVTa CSA,and the improved radiation tolerance is primarily attributed to the relaxation stage and long-term defect evolution rather than the ballistic *** results can provide fundamental insights into irradiation-induced defects evolution in refractory CSAs.

关键词： concentrated solid-solution alloy primary radiation damage molecular dynamics simulation

A telomere-to-telomere genome assembly of Zhonghuang 13,a widely-grown soybean variety from the original center of Glycine max

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The Crop Journal 2024年第1期12卷 142-153页

作者： Anqi Zhang Tangchao Kong Baiquan Sun Shizheng qiu Jiahe Guo Shuyong Ruan Yu Guo Jirui Guo Zhishuai Zhang Yue Liu Zheng Hu Tao Jiang Yadong Liu Shuqi Cao Shi Sun Tingting Wu Huilong Hong Bingjun Jiang Maoxiang Yang Xiangyu Yao Yang Hu Bo Liu Tianfu han Yadong Wang Center for Bioinformatics School of Computer Science and TechnologyHarbin Institute of TechnologyHarbin 150001HeilongjiangChina Ministry of Agriculture Key Laboratory of Soybean Biology(Beijing) Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China

Soybean(Glycine max)stands as a globally significant agricultural crop,and the comprehensive assembly of its genome is of paramount importance for unraveling its biological characteristics and evolutionary ***,previous soybean genome assemblies have harbored gaps and incompleteness,which have constrained in-depth investigations into ***,we present Telomere-to-Telomere(T2T)assembly of the Chinese soybean cultivar Zhonghuang 13(ZH13)genome,termed ZH13-T2T,utilizing PacBio Hifi and ONT ultralong *** employed a multi-assembler approach,integrating Hifiasm,NextDenovo,and Canu,to minimize biases and enhance assembly *** assembly spans 1,015,024,879 bp,effectively resolving all 393 gaps that previously plagued the reference *** annotation efforts identified 50,564 high-confidence protein-coding genes,707 of which are ***13-T2T revealed longer chromosomes,421 not-aligned regions(NARs),112 structure variations(SVs),and a substantial expansion of repetitive element compared to earlier ***,we identified 25.67 Mb of tandem repeats,an enrichment of 5S and 48S rDNAs,and characterized their genotypic *** summary,we deliver the first complete Chinese soybean cultivar T2T *** comprehensive annotation,along with precise centromere and telomere characterization,as well as insights into structural variations,further enhance our understanding of soybean genetics and evolution.

关键词： Soybean Telomere-to-Telomere assembly Zhonghuang 13 Structure variations

环境支持与乒乓球运动参与的关系:自我效能的中介与技术知识的调节作用

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北京体育大学学报 2024年第8期47卷 105-118页

作者：刘菡邱招义何敬堂云南民族大学体育学院云南昆明650500 北京体育大学北京100084 淮南师范学院体育学院安徽淮南232038

探究环境支持与乒乓球运动参与行为之间的关系,并探讨自我效能和技能知识在两者之间的中介和调节作用。采用便利抽样,以394名乒乓球爱好者为调查对象,使用自编量表对其进行问卷调查。结果显示:人际支持正向预测参与行为,自我效能在人际... 详细信息

探究环境支持与乒乓球运动参与行为之间的关系,并探讨自我效能和技能知识在两者之间的中介和调节作用。采用便利抽样,以394名乒乓球爱好者为调查对象,使用自编量表对其进行问卷调查。结果显示:人际支持正向预测参与行为,自我效能在人际关系与参与行为的关系中起到了部分中介作用;信息支持正向预测参与行为,自我效能在信息支持与参与行为的关系中起到了完全中介作用;技能知识调节了中介模型的前半段路径。研究提示:目前大众乒乓球运动具备“强人际交往”“重技能知识”的特点,人际支持与自我效能的交互作用负向、间接影响乒乓球爱好者的参与行为。对于“乒乓球运动参与”,建议优化大众乒乓球比赛模式、创新竞赛管理系统,使参赛者能够找到水平相当的对手,进而激发其参与乒乓球运动的积极性。

关键词：乒乓球运动参与行为环境支持技能知识

颅内压相关参数预测重型创伤性脑损伤预后的研究进展

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中华创伤杂志 2024年第4期40卷 336-342页

作者：夏晶韩冰莎王炬冯光新乡医学院研究生院新乡453004 河南省人民医院神经外科重症监护病房郑州450003

重型创伤性脑损伤(sTBI)患者常存在颅内血肿、脑积水等和全身并发症如多器官功能障碍、急性呼吸窘迫综合征等较为严重的并发症。目前,颅内压被认为是sTBI临床管理中最重要的目标导向参数,可实时监测颅内疾病进展,从而最大限度降低继发... 详细信息

重型创伤性脑损伤(sTBI)患者常存在颅内血肿、脑积水等和全身并发症如多器官功能障碍、急性呼吸窘迫综合征等较为严重的并发症。目前,颅内压被认为是sTBI临床管理中最重要的目标导向参数,可实时监测颅内疾病进展,从而最大限度降低继发性脑损伤等并发症的发生率。但单纯颅内压监测存在一定局限性,如颅内压数据信息不完整及数据信息滞后等。临床上往往还需采用除颅内压以外的其他相关参数辅助进行全面监测,包括血管压力反应指数(PRx)、平均颅内压波幅(MWA)、颅内压波幅与颅内压的相关系数(RAP),颅内压波幅与动脉血压波幅的相关系数(IAAC)等,通过精确反映脑顺应性及脑血管自动调节能力等进一步在临床中辅助指导sTBI治疗策略与评估患者预后。但目前临床尚缺乏对颅内压相关参数的全面认识。为此,笔者就颅内压相关参数在预测sTBI预后中应用的研究进展进行综述,为其临床应用与未来研究提供参考。

关键词：颅脑损伤颅内压脑血管循环顺应性压力反应指数

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吲哚美辛二元醇质体凝胶剂的制备与质量研究

安徽化工 2024年第4期50卷 58-64,68页

作者：于秋菊徐州生物工程职业技术学院江苏徐州221006

目的:优化吲哚美辛(IND)二元醇质体凝胶的处方工艺,并进行药效学研究和稳定性考查。方法:以平均粒径Y1和包封率Y2为因变量,磷脂用量X1、混合醇用量X_(2)、丙二醇用量X_(3)为自变量,采用星点设计-效应面法优化IND二元醇质体的制备工艺,... 详细信息

目的:优化吲哚美辛(IND)二元醇质体凝胶的处方工艺,并进行药效学研究和稳定性考查。方法:以平均粒径Y1和包封率Y2为因变量,磷脂用量X1、混合醇用量X_(2)、丙二醇用量X_(3)为自变量,采用星点设计-效应面法优化IND二元醇质体的制备工艺,并与卡波姆凝胶基质以1∶1比例研和制备IND二元醇质体凝胶,通过改良的Franz扩散池法考查IND凝胶、纳米乳与二元醇质体凝胶的体外透皮性能并进行IND二元醇质体的初步稳定性考查;采用热板法和醋酸扭体法考查IND三种制剂的体内镇痛作用。结果:最优处方工艺为IND0.50g,磷脂0.46g,混合醇8.45mL,丙二醇2.15mL,制备的IND二元醇质体凝胶的平均粒径为(81.80±1.04)nm,包封率为(72.61±1.01)%,与预测值相对误差分别为2.36%、2.29%。IND二元醇质体凝胶的稳态渗透速率常数为(0.646 7±0.007 30)μg·cm^(-2)·h^(-1),是普通凝胶的2.16倍,纳米乳的1.43倍;IND二元醇质体凝胶能明显抑制小鼠的热板添足反应和醋酸扭体反应。结论:制备的IND二元醇质体凝胶剂粒径小,分布较为均匀,具有良好的体外透皮吸收性能和体内镇痛作用,稳定性良好,为IND用于局部炎症治疗的新剂型研究提供依据。

关键词：吲哚美辛二元醇质体凝胶星点-效应面法经皮渗透稳定性

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Bright, photostable and long-circulating NIR-Ⅱ nanoparticles for whole-process monitoring and evaluation of renal transplantation

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National Science Review 2024年第2期11卷 207-220页

作者： Rongyuan Zhang Ping Shen Yu Xiong Tianjing Wu Gang Wang Yucheng Wang Liping Zhang han Yang Wei He Jian Du Xuedong Wei Siwei Zhang Zijie qiu Weijie Zhang Zheng Zhao Ben Zhong Tang Clinical Translational Research Center of Aggregation-Induced Emission The Second Affiliated HospitalSchool of MedicineSchool of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen(CUHK-Shenzhen) Center for AIE Research Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and Engineering Shenzhen University School of Chemistry Xiangtan University HKUST-Shenzhen Research Institute Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction The Hong Kong University of Science and Technology Department of Urology The First Affiliated Hospital of Soochow University AIE Institute

Kidney transplantation is the gold standard for the treatment of end-stage renal diseases(ESRDs). However,the scarcity of donor kidneys has caused more and more ESRD patients to be stuck on the waiting list for transplant surgery. Improving the survival rate for renal grafts is an alternative solution to the shortage of donor kidneys. Therefore, real-time monitoring of the surgical process is crucial to the success of kidney transplantation, but efficient methods and techniques are lacking. Herein, a fluorescence technology based on bright, photostable and long-circulating aggregation-induced emission(AIE) active NIR-II nano-contrast agent DIPT-ICF nanoparticles for the whole-process monitoring and evaluation of renal transplantation has been reported. In the aggregated state, DIPT-ICF exhibits superior photophysical properties compared with the commercial dyes IR-26 and IR-1061. Besides, the long-circulating characteristic of the AIE nano-contrast agent helps to achieve renal angiography in kidney retrieval surgery,donor kidney quality evaluation, diagnosing vascular and ureteral complications, and assessment of renal graft reperfusion beyond renovascular reconstruction, which considerably outperforms the clinically approved indocyanine green(ICG).

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