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Analysis of factors impacting postoperative pain and quality of life in patients with mixed hemorrhoids:A retrospective study

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 731-739页

作者： Xiao-Wen Sun Jing-yi Xu Chang-Zhen Zhu Si-jia Li Lu-jia Jin Zhi-Dong Zhu Department of Gastrointestinal Surgery Tsinghua University Affiliated Beijing Tsinghua Changgeng HospitalBeijing 102218China Surgical Department Tsinghua University Affiliated Beijing Tsinghua Changgeng HospitalBeijing 102218China

BACKGROUND Hemorrhoids are among the most common and frequently encountered chronic anorectal diseases in anorectal *** are venous clusters formed by con-gestion,expansion,and flexion of the venous plexus in the lower part of the *** hemorrhoids bleed easily and recurrently,and this can result in severe ***,they may have a negative effect on the health of the patient and surgical treatment is ***-Morgan hemorrhoidectomy has been widely used since 1937 for the treatment of grade III and IV ***-ever,most patients experience different degrees of postoperative pain that may cause *** mixed hemorrhoids *** The clinical data of patients with mixed hemorrhoids who underwent Milligan-Morgan hemorrhoidectomy were collected *** basic character-istics of the enrolled patients with mixed hemorrhoids were recorded,and based on the Goligher clinical grading system,the hemorrhoids were classified as grades III or *** endpoint of this study was the disappearance of pain in all *** data were presented as mean±SD,such as age,pain score,and QoL ***’s t-test was used to compare the *** A total of 164 patients were *** distribution of the visual analog scale pain scores of all patients at 3,7,14 and 28 d after surgery showed that post-surgery pain was significantly reduced with the passage of *** days after the operation,the pain had completely disappeared in some ***-eight days after the surgery,none of the patients experienced any *** the World Health Or-ganization Quality of Life-BREF self-reporting questionnaire scores of patients between 14 and 28 d after surgery,we observed that the quality-of-life scores of the patients post-surgery had significantly *** were six items that were compared at 14-and 28-d *** mean QoL score 28 d after surgery(4.79±0.46)was higher than that at 14 d p

关键词： Hemorrhoids Mixed hemorrhoids Milligan organ hemorrhoidectomy Postoperative pain Quality of life Anesthesia mode

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Early colorectal cancer screening–no time to lose

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World Journal of Gastroenterology 2024年第23期30卷 2959-2963页

作者： ying Wang Zheng-Long Wu yi-Gang Wang Hui Wang Xiao-Yuan jia College of Life Sciences and Medicine Zhejiang Sci-Tech UniversityHangzhou 310018Zhejiang ProvinceChina Department of Oncology Zhejiang Xiaoshan HospitalHangzhou 310018Zhejiang ProvinceChina

In this editorial,we comment on the article entitled“Stage at diagnosis of colorectal cancer through diagnostic route:Who should be screened?”by Agatsuma et *** cancer(CRC)is emerging as an important health issue as its incidence continues to rise globally,adversely affecting the quality of *** the public has become more aware of CRC prevention,most patients lack screening *** poor lifestyle practices can lead to CRC and symptoms can appear in the early stages of ***,due to the lack of awareness of the disease,most of the CRC patients are diagnosed already at an advanced stage and have a poor prognosis.

关键词： Colorectal cancer The immunochemical fecal occult blood test Diagnostic route Cancer screening Stage at diagnosis

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A semi-analytical pressure and rate transient analysis model for inner boundary and propped fractures exhibiting dynamic behavior under long-term production conditions

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Petroleum Science 2024年第4期21卷 2520-2535页

作者： Lin-Song Cheng Chong Cao Quan-Yu Pan Pin jia Ren-yi Cao Zhi-Kai Wang Jun-Jie Shi College of Petroleum Engineering China University of Petroleum (Beijing) Sinopec Petroleum Exploration and Production Research Institute CNOOC Research Institute State Key Laboratory of Water Resources Protection and Utilization in Coal Mining

The loss of hydrocarbon production caused by the dynamic behavior of the inner boundary and propped fractures under long-term production conditions has been widely reported in recent studies. However,the quantitative relationships for the variations of the inner boundary and propped fractures have not been determined and incorporated in the semi-analytical models for the pressure and rate transient analysis. This work focuses on describing the variations of the inner boundary and propped fractures and capturing the typical characteristics from the pressure transient curves.A generalized semi-analytical model was developed to characterize the dynamic behavior of the inner boundary and propped fractures under long-term production conditions. The pressure-dependent length shrinkage coefficients, which quantify the length changes of the inner zone and propped fractures, are modified and incorporated into this multi-zone semi-analytical model. With simultaneous numerical iterations and numerical inversions in Laplace and real-time space, the transient solutions to pressure and rate behavior are determined in just a few seconds. The dynamic behavior of the inner boundary and propped fractures on transient pressure curves is divided into five periods: fracture bilinear flow(FR1),dynamic PFs flow(FR2), inner-area linear flow(FR3), dynamic inner boundary flow(FR4), and outer-area dominated linear flow(FR5). The early hump during FR2 period and a positive upward shift during FR4period are captured on the log-log pressure transient curves, reflecting the dynamic behavior of the inner boundary and propped fractures during the long-term production *** transient pressure behavior will exhibit greater positive upward trend and the flow rate will be lower with the shrinkage of the inner boundary. The pressure derivative curve will be upward earlier as the inner boundary shrinks more rapidly. The lower permeability caused by the closure of un-propped fractures in the inner zo

关键词： Semi-analytical model Length shrinkage Dynamic behavior Boundary changes Transient behavior

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Research progress on the development of hepatocyte growth factor/c-Met signaling pathway in gastric cancer:A review

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3397-3409页

作者： Wu-Jie Wei Ya-Li Hong yi Deng Guan-Liang Wang jiang-Tao qiu Fang Pan Department of Oncology People's Hospital of Chongqing HechuanChongqing 401520China Department of Cardiovascular People's Hospital of Chongqing HechuanChongqing 401520China Intensive Care Unit People's Hospital of Chongqing HechuanChongqing 401520China Department of Gastrointestinal Surgery Beijing Tsinghua Changgung HospitalBeijing 100084China

Hepatocyte growth factor(HGF)and its receptor,c-Met,play important roles in the occurrence,development,and treatment of gastric cancer(GC).This review explored the function of the HGF/c-Met signaling pathway in GC and its potential targeted therapeutic *** one of the most common malignant tumors worldwide,GC has a complex pathogenesis and limited therapeutic ***,a thorough understanding of the molecular mechanism of GC is very important for the development of new therapeutic *** HGF/c-Met signaling pathway plays an important role in the proliferation,migration,and invasion of GC cells and has become a new therapeutic *** review summarizes the current research progress on the role of HGF/c-Met in GC and discusses targeted therapeutic strategies targeting this signaling pathway,providing new ideas and directions for the treatment of GC.

关键词： Targeted therapy Hepatocyte growth factor c-Met Gastric cancer Prognosis assessment Review

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Impact of coupling coordination development of port and city environments on urban economic competitiveness:Evidence from the coastal port cities in eastern China

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Ecological Economy 2024年第1期20卷 53-71页

作者： LI Zhen-qiang yi ying LI jia-li YOU Xiao-yue ZHOU qiu-yang School of Economics and Management Hunan Institute of Science and TechnologyYueyang 414006CHINA School of Urban and Regional Science Shanghai University of Finance and EconomicsShanghai 200433CHINA

Promoting the coupling coordination development of port and its hinterland city environments is an important way to improve urban economic *** on relevant data of 13 coastal port cities in eastern China from 2000 to 2018,this study explores the coupling coordination development of port and city environments and its impact on urban economic competitiveness by constructing the coupling coordination degree model and the panel threshold *** research results show that:(1)In terms of the coupling coordination development of port and city environments,most coastal ports and their hinterland cities are in a state of moderate or serious ***,the degree of coupling coordination of port and city environments needs to be further improved;(2)The coupling coordination degree of port and city environments has a significant impact on urban economic competitiveness,and this effect gradually increases with the development of the ports and the urban *** the variables that impact the urban economic competitiveness,fixed assets investment and foreign trade are significant factors that can enhance urban economic competitiveness.(3)At present,there is a“U-shaped”relationship between the coupling coordination degree of port-city environments and the urban economic *** relationship lies on the right side of the inflection point of the“U-shaped”***,following the concept of assigning priority to ecological development,expanding fixed assets investment and actively developing foreign trade can further enhance the urban economic competitiveness.

关键词： coastal ports city environments coupling coordination degree urban economic competitiveness threshold effect

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细胞、组织冻存方法及应用的研究进展

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中国生物制品学杂志 2017年第5期30卷 546-550页

作者：邱佳裔贾晓青黄岗谭树华中国药科大学生命科学与技术学院江苏南京210009

将细胞及组织置液氮中进行低温保存可使其暂时脱离生长状态,并长久保存其生物性能,主要包括传统慢速冻存及玻璃化冻存两种方法。在冻存过程中,冷冻保护剂(cryoprotective agent,CPA)发挥了较关键的作用,其可避免细胞及组织在冻存过程中... 详细信息

将细胞及组织置液氮中进行低温保存可使其暂时脱离生长状态,并长久保存其生物性能,主要包括传统慢速冻存及玻璃化冻存两种方法。在冻存过程中,冷冻保护剂(cryoprotective agent,CPA)发挥了较关键的作用,其可避免细胞及组织在冻存过程中低温对细胞造成的损害,更好地保存细胞的生物性能,CPA包括渗透型和非渗透型两种类型。细胞及组织的冻存技术已广泛应用于多个领域,尤其在实验室的药物活性检测和生殖能力保存方面的作用较突出。本文主要从细胞冻存的基本原理、方法及应用的研究进展作一综述。

关键词：细胞组织冻存冷冻保护剂药物活性生殖能力

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Water-Driven Malleable,Weldable and Eco-Friendly Recyclable Carbon Fiber Reinforced Dynamic Composites

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Chinese Journal of Chemistry 2024年第5期42卷 516-522页

作者： Ping Yu Qirui Huang yi Wang Wan Peng Zichen jia Haiyue Wang Juanjuan Ma Chunyu Wang Xuzhou Yan School of Environmental and Chemical Engineering Jiangsu Key Laboratory of Function Control Technology for Advanced MaterialsJiangsu Ocean UniversityLianyungangJiangsu222005 China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai200240 China

Traditional carbon fiber-reinforced polymers based on thermoset matrix have been extensively used in the fields of wind turbine blades,automotive sector,and aerospace,among many ***,there is still a major challenge of recycling those polymers due to the high cost and adverse impacts on the *** this work,we apply a polyimine network as matrix,which possess considerable tensile and thermal properties,to prepare the carbon fiber reinforced polyimine materials with trifluoromethyl diphenoxybenzene units(CFRFP)using a prepreg-based compression molding *** CFRFP can be reshaped or reprocessed by heat or with water rapidly,and exhibited multifunction,including welding,chemical recycling,*** unique findings gained from our study will facilitate the manufacturing capability and enrich the types of fiber-reinforced composites.

关键词： Dynamic chemistry Green chemistry Fiber-reinforced composites Fluoropolyimine Welding Reshaping Recycling Renewable resources

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Brachiopods from the Silurian “Lower Red Beds” of Wuhan（E. Hubei， South China）: paleoecological and paleogeographical implications

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Journal of Earth Science 2024年

作者： jia-yi yin yi-Long Liu Lie-Bin Huang yi-Ming Gong Rui-Wen Zong School of Earth Sciences， China University of Geosciences Faculty of Land and Resources Engineering， Kunming University of Science and Technology State Key Laboratory of Biogeology and Environmental Geology， China University of Geosciences

The age and sedimentary environment of the Silurian “Lower Red Beds” (LRBs)， which occur widely in South China， have long been controversial because of the scarcity of index fossils. Recently， these beds have been dated by trilobites as middle-late Aeronian to early Telychian in age. Here， we report abundant brachiopods from the LRBs in Wuhan， Middle Yangtze Region， including atrypides (Meifodia hunanensis， Zygospiraella sp. 1， Zygospiraella sp. 2 and Nalivkinia? sp.)， spiriferides (Striispirifer acuminiplicatus， Striispirifer? sp.)， strophomenides (Eostropheodonta? sp. and Katastrophomena modesta)， and linguliformeans (Anomaloglossa? sp. and Orbiculoidea? sp.). Most of these are common in the Leijiatun， Xiangshuyuan， Shihniulan， Niuchang， Lojoping， and Shamao formations in the Upper Yangtze Region. The discovery of brachiopods from the LRBs in Wuhan not only enrich the biodiversity of the LRBs in the Yangtze Region， where Meifodia， Zygospiraella， Katastrophomena and Eostropheodonta are first found in the LRBs， but also expand the paleogeographical distribution of brachiopods to Middle-Lower Yangtze Region that first radiated after the end-Ordovician extinction. In addition， this brachiopod fauna also provides important implications for the sedimentary environment of LRBs during the Llandovery， which is usually developed in the nearshore shallow-water (BA1-2)， althought this paper extends to the deeper parts of the shallow-marine (BA3-4).

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Boosted photocatalytic removal of NO using direct Z-scheme UiO-66-NH_(2)/Bi_(2)MoO_(6) nanoflowers heterojunction:mechanism insight and humidity effect

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Rare Metals 2024年第8期43卷 3758-3770页

作者： jiang-Yu-Shan Liang Hai-Tao Ren Abdelkader Labidi qiu-Hui Zhu Qi-Bing Dong Ahmed A.Allam Ahmed Rady Chuan-yi Wang School of Environmental Science and Engineering Shaanxi University of Science and TechnologyXi'an 710021China Zoology Department Faculty of ScienceBeni-Suef UniversityBeni-Suef 6251lEgypt Department of Zoology College of ScienceKing Saud University11451 RiyadhSaudi Arabia

In practical applications,relative humidity in the air is a key factor affecting the photocatalytic removal of NO,which is often overlooked in previous ***,we developed a direct Z-scheme UiO-66-NH_(2)/Bi_(2)MoO_(6)heterojunction with a nanoflower-like structure to systematically investigate the effect of relative humidity on photocatalytic removal of *** optimized heterojunction for the removal efficiency of NO was 71.6%at1.07 mg·m^(-3)NO concentration(relative humidity=10%),and the generation of NO_(2) was only 1.1%.Interestingly,with the increase in relative humidity,it showed a higher inhibition effect on NO_(2),while the removal of NO decreased slightly(8%),which might be attributed to the affinity effect of NO_(2) with water molecules and the competitive adsorption of H_(2)O and NO on the surface of the heterojunction ***,the reaction pathways of NO removal at the developed heterojunctions were revealed by in situ DRIFTS *** work provides a novel vision for the development of direct Z-scheme heterojunction photocatalysts to effectively remove NO and inhibit the formation of toxic intermediate NO_(2) under different humidities.

关键词： NO removal Relative humidity Direct Z-scheme Bismuth molybdate Visible-light photocatalysis

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Woven fabric triboelectric nanogenerators for human-computer interaction and physical health monitoring

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Nano Research 2024年第6期17卷 5540-5548页

作者： Yu Miao Mengjuan Zhou jia yi Yanyan Wang Guangjin Tian Hongxia Zhang Wenlong Huang Wenhao Wang Ronghui Wu Liyun Ma College of Textile and Clothing Xinjiang UniversityUrumqi 830046China College of Textiles Donghua UniversityShanghai 201620China College of Physics Xiamen UniversityXiamen 201620China Department of Bioengineering Imperial College LondonLondon SW72AZUK

Triboelectric nanogenerator(TENG)converts mechanical energy into valuable electrical energy,offering a solution for future energy *** an indispensable part of TENG,textile TENG(T-TENG)has incredible advantages in harvesting biomechanical energy and physiological signal ***,the application of T-TENG is restricted,partly because the fabric structure parameter and structure on T-TENG performance have not been fully *** study comprehensively investigates the effect of weaving structure on fabric TENGs(F-TENGs)for direct-weaving yarn TENGs and post-coating fabric *** direct-weaving F-TENGs,a single-yarn TENG(Y-TENG)with a core-sheath structure is fabricated using conductive yarn as the core layer yarn and polytetrafluoroethylene(PTFE)filaments as the sheath *** fabrics with five different sets of parameters were designed and *** post-coating F-TENGs,fabrics with weaving structures of plain,twill,satin,and reinforced twill were fabricated and coated with conductive silver ***,the twill F-TENGs have the best electrical outputs,followed by the satin F-TENGs and plain weave ***,the increase of the Y-TENG gap spacing was demonstrated to improve the electrical output ***,T-TENGs are demonstrated for human-computer interaction and self-powered real-time *** systematic work provides guidance for the future T-TENG’s design.

关键词： single-yarn triboelectric nanogenerators woven fabric triboelectric nanogenerators fabric weaving structures and parameters human-computer interaction physical health monitoring

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