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The Advent of a New Era of Antenatal Cardiotocography

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Maternal-Fetal Medicine 2022年第2期4卷 93-94页

作者： Yang Zhang qiongjie zhou Xiaotian Li Department of Obstetrics Obstetrics and Gynecology Hospital of Fudan University Shanghai 200011 China

Fetal monitoring was first introduced in the 1960 s when cardiotocography(CTG)was first *** the rapid development of electronic and information technology,CTG is commonly utilized across the ***,further standardization guidelines were established for CTG by the American College of Obstetricians and Gynecologists(ACOG)in 2009.1 CTG is also recommended as a regular monitoring method for high-risk pregnancies.

关键词： natal utilized College

Normal labor of Chinese women undergoing trial of labor after cesarean delivery

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Normal labor of Chinese women undergoing trial of labor afte...

综合医院与专科医院孕产妇VTE防治现状的调查

2019长三角围产医学学术会议暨浙江省围产医学学术大会

作者： Yan Xu qiongjie,zhou Qianqian Chen Lu Guo Lu Zhang Tingting Zhu Jianyu Ye Yu Xiong Department of Obstetrics Obstetrics and Gynecology Hospital of Fudan University

Introduction. The objective of this study was to compare labor progress of Chinese women undergoing TOLAC with those without a previous cesarean delivery. Material and methods. A matched case-control historical cohort study was conducted of vertex singleton pregnant Chinese women with spontaneous labor between 35 0/7 and 41 6/7 gestational weeks. The controls were matched for maternal age, gestational weeks and birth weight of newborn. We examined time interval for each centimeter of cervical dilation and compared labor progression by spontaneous labor in women undergoing TOLAC, nulliparas and primiparas with a prior vaginal delivery. Results. 152 women undergoing TOLAC were compared with their matched nulliparous and primiparous controls. The labor patterns were similar for women undergoing TOLAC and nulliparas. Although there was significant differences of duration from 4～5 cm(p=0.013), the median time of latent phase, active phase and first stage did not differ significantly between TOLAC women and nulliparas. The second stage of TOLAC women had a median of 14.5 minutes faster than that of nulliparous women(31.5 vs 41.0 minutes, p<0.001). When compared to primiparas, TOLAC women had a median of 2.2 hours longer first stage(6.0 vs 3.8 hours, p<0.001) and a median of 21.5 minutes longer second stage(31.5 vs 10.0 minutes, p<0.001). Conclusions. Chinese women undergoing TOLAC had a similar first stage of labor with nulliparas but a faster second stage than nulliparas. Compared to primiparas, women undergoing TOLAC have a longer progress both in the first and second stage. Obstetricians should manage women undergoing TOLAC with the same standards as nulliparas.

关键词： trial of labor after cesarean delivery vaginal birth after cesarean delivery labor

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中华妇产科杂志 2021年第5期56卷 310-316页

作者：崔宇童李笑天周琼洁复旦大学附属妇产科医院产科上海200011

目的调查国内综合医院与专科医院孕产妇静脉血栓栓塞症(VTE)的防治现状。方法本研究采用横断面调查的方式,以调查问卷的形式收集了全国112家医院2019年1月1日至12月31日期间的VTE防治现状,包括基本信息、资源可及率、医院制度及策略等... 详细信息

目的调查国内综合医院与专科医院孕产妇静脉血栓栓塞症(VTE)的防治现状。方法本研究采用横断面调查的方式,以调查问卷的形式收集了全国112家医院2019年1月1日至12月31日期间的VTE防治现状,包括基本信息、资源可及率、医院制度及策略等。按照医院的性质分为综合医院组(70家)和专科医院组(42家),比较两组医院基本资料、VTE诊疗资源及防治制度,以及VTE风险评估表的选择情况。采用logistic回归模型分析两组医院孕产妇VTE的病例数占比及相关影响因素。结果(1)综合医院组的中位年分娩量显著低于专科医院组(分别为3428、9969例,P<0.01),CT肺血管造影(CTPA)的可及率显著高于专科医院[分别为92.9%(65/70)和59.5%(25/42),P<0.01],进行产科VTE风险评估的比例显著高于专科医院组[分别为85.7%(60/70)和66.7%(28/42),P=0.017]。(2)在使用VTE风险评分表的88家医院中,专科医院组对于产科VTE指南推荐的评估表的利用率(78.6%,22/28)高于综合医院组(48.3%,29/60),两组相比,差异有统计学意义(P=0.007)。(3)综合医院组孕产妇VTE病例数占比为0.126%(360/286517),专科医院组为0.032%(154/484111),logistic回归模型分析显示,专科医院组孕产妇的VTE病例数占比显著低于综合医院组(OR=0.253,95%CI为0.209~0.305,P<0.01)。校正医院级别、B超和CTPA可及率、是否建立VTE风险评估和产科VTE制度后,专科医院组孕产妇的VTE病例数占比仍显著低于综合医院组(OR=0.307,95%CI为0.251~0.376,P<0.01)。结论综合医院较专科医院诊断VTE的资源可及率较高,同时VTE风险评估制度落实较好;但专科医院产科的VTE指南利用率高于综合医院。综合医院孕产妇的VTE病例数占比高于专科医院。

关键词：医院,综合医院,专科孕妇静脉血栓栓塞医院管理调查和问卷

超声估测胎儿体重和多普勒参数评价晚发型胎儿生长受限的临床价值

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中华超声影像学杂志 2018年第9期27卷 789-794页

作者：朱晨任芸芸吴江南周琼洁复旦大学附属妇产科医院超声科上海200011 复旦大学附属妇产科医院流行病学教研室上海200011 复旦大学附属妇产科医院产科上海200011

目的探讨INTERGROWTH和Hadlock胎儿体重估测（estimated fetal weight，EFW）标准以及多普勒参数预测晚发型胎儿生长受限（fetal growth restriction，FGR）的准确性。方法本研究为前瞻性队列研究。收集2015年3月至2016年3月在复旦大学... 详细信息

目的探讨INTERGROWTH和Hadlock胎儿体重估测（estimated fetal weight，EFW）标准以及多普勒参数预测晚发型胎儿生长受限（fetal growth restriction，FGR）的准确性。方法本研究为前瞻性队列研究。收集2015年3月至2016年3月在复旦大学附属妇产科医院建卡并分娩的32～41周单胎妊娠孕妇。每2周监测超声指标（包括胎儿生长测量、脐动脉和大脑中动脉），采用分娩前7d内最后一次超声测量值，分别按照INTERGR0WTH和Hadlock标准计算胎儿体重，同时采用Logistic回归方程建立EFW、脐动脉、大脑中动脉单参数模型和多参数联合模型预测晚发型FGR。根据新生儿出生体重是否低于同胎龄应有体重第10百分位数（〈10^th％），分为FGR组（晚发型FGR，出生体重〈10^th％）和对照组（非FGR，出生体重≥10^th％）。并对两种标准预测FGR行ROC曲线分析。结果820例孕妇符合人组条件，排除144例失访病例。最终获得有效数据676例，分为FGR组116例，对照组560例。ROC曲线分析显示，Hadlock—EFWc预测晚发型FGR的截断值为22．6^th％，对应的敏感性、特异性和曲线下面积（AUC）分别为87．3％、82．8％和0．930（0．908—0．953），均高于INTERGROWTH—EFWc的预测价值[截断值为27．5^th％，对应的敏感性、特异性和AUC分别为71．4％、83．7％和0．847（0．807—0．888）]。多普勒参数单独预测晚发型FGR的价值较低（均AUC〈0．7），多参数联合模型（combined model—Ⅰ和Ⅱ）预测FGR的价值较高（AUC分别为0．865和0．936），与其对应的胎儿体重预测模型的准确性相似。结论Hadlock和INTERGROWTH的EFW标准预测本地区晚发型FGR的临床价值均较高，但是Hadlock标准的预测准确性更优。多普勒参数（脐动脉、大脑中动脉）预测晚发型FGR的准确性较低，建议高危孕妇选择性监测。

关键词：超声检查胎儿生长受限小于胎龄儿胎儿体重 INTERGROWTH标准 Hadlock标准

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产科血栓栓塞性疾病的孕期管理

中国计划生育和妇产科 2021年第3期13卷 8-10页

作者：周琼洁李笑天复旦大学附属妇产科医院产科上海200011

近年来,在国内孕产妇死亡率逐渐降低(特别是当孕产妇死亡率降低到10/10万以下)的情况下,血栓性疾病已成为导致孕产妇死亡的重要原因之一。静脉血栓栓塞性疾病(venous thromboembolism,VTE)包含深静脉血栓(deep vein thrombosis,DVT)及... 详细信息

近年来,在国内孕产妇死亡率逐渐降低(特别是当孕产妇死亡率降低到10/10万以下)的情况下,血栓性疾病已成为导致孕产妇死亡的重要原因之一。静脉血栓栓塞性疾病(venous thromboembolism,VTE)包含深静脉血栓(deep vein thrombosis,DVT)及肺栓塞(pulmonary embolism,PE),现已成为国内非预期死亡的首要原因之一,其中部分患者是可预防、可治疗的。

关键词：血栓栓塞性疾病产科管理

双胎妊娠孕期规范化诊疗和管理对围产儿预后影响研究

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中国实用妇科与产科杂志 2017年第6期33卷 590-594页

作者：齐嫣婷周琼洁沈婕程海东刘彩霞李笑天熊钰复旦大学附属妇产科医院产科上海200090 中国医科大学附属盛京医院产科辽宁沈阳110004

目的探讨双胎妊娠诊治规范和管理模式建立前后双胎妊娠绒毛膜性诊断的准确性和围产儿预后的改变。方法收集2010-01-01—2015-12-31在复旦大学附属妇产科医院杨浦院区产科分娩、经产后肉眼检查或胎盘胎膜病理检查明确绒毛膜性质的双胎妊... 详细信息

目的探讨双胎妊娠诊治规范和管理模式建立前后双胎妊娠绒毛膜性诊断的准确性和围产儿预后的改变。方法收集2010-01-01—2015-12-31在复旦大学附属妇产科医院杨浦院区产科分娩、经产后肉眼检查或胎盘胎膜病理检查明确绒毛膜性质的双胎妊娠孕妇444例,以本院2013-06-01起对双胎妊娠实施规范化诊疗和管理(简称"规范")为界分组,比较规范实施前后绒毛膜性诊断的准确性、妊娠结局及围产儿预后方面的差异。结果 (1)规范实施前后,收集病例的年龄、身高、体重之间差异无统计学意义(P>0.05)。(2)规范实施后,产前超声诊断绒毛膜性的比例较实施前明显增加(91.7%vs.70.2%,P0.05)。(3)规范实施后的择期剖宫产分娩孕周明显晚于规范实施前[(37.17±0.45)周vs.(36.93±0.51)周,P0.05),母婴同室比例在规范实施后高于规范实施前(58.3%vs.54.1%,P<0.05),新生儿NICU入住率、出生后直接转院比例及放弃抢救比例低于规范实施前(37.4%vs.37.7%,4.3%vs.7.3%,0 vs.0.9%,P<0.05)。结论双胎妊娠诊治规范和管理模式的建立有利于围产儿预后的改善。

关键词：双胎妊娠诊疗规范绒毛膜性围产儿预后

Selection of magnetic anion exchange resins for the removal of dissolved organic and inorganic matters

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Journal of Environmental Sciences 2012年第11期24卷 1891-1899页

作者： qiongjie Wang Aimin Li Jinnan Wang Chengdong Shuang State Key Laboratory of Pollution Control and Resources Reuse School of the EnvironmentNanjing UniversityNanjing 210046China

Four magnetic anion exchange resins （MAERs） were used as adsorbents to purify drinking water. The effect of water quality （pH, temperature, ionic strength, etc.） on the performance of MAER for the removal of dissolved organic matter （DOM） was also investigated. Among the four studied MAERs, the strong base resin named NDMP- 1 with high water content and enhanced exchange capacity exhibited the highest removal rate of dissolved organic carbon （DOC）（48.9% removal rate） and UV-absorbing substances （82.4% removal rate） with a resin dose of 10 mL/L after 30 rain of contact time. The MAERs could also effectively remove inorganic matter such as sulfate, nitrate and fluoride. Because of the higher specific UV absorbance （SUVA） value, the DOM in the raw water was found to be removed more effectively than that in the clarified water by NDMP resin. The temperature showed a weak influence on the removal of DOC from 6 to 26℃, while a relatively strong one at 36℃. The removal of DOM by NDMP was also affected to some extent by the pH value. Moreover, increasing the sulfate concentration in the raw water could decrease the removal rates of DOC and UV-absorbing substances.

关键词： magnetic anion exchange resins dissolved organic matter inorganic anions water quality

Recent advances in the synthesis and application of N-heterocyclic carbene-based molecular cages

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Science China Chemistry 2024年第5期67卷 1510-1523页

作者： qiongjie Chai Lixin Duan Yanzhe Ma Tianheng Hou Tao Tu Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of ChemistryFudan UniversityShanghai 200438China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

N-Heterocyclic carbene(NHC)-based cages have emerged as a prominent and dynamic research area within the research field of chemistry. Leveraging the distinctive electronic and steric properties of NHC ligands, the design, synthesis, and application of these corresponding cages have garnered substantial scholarly interest. In recent years, we have witnessed the successful fabrication of diverse NHC-based cages through a range of synthetic methodologies, which hold significant potential for applications in molecular recognition and catalysis. In this review, we delve into the foundational synthetic strategies that underlie the creation of NHC-based cages, employing approaches encompassing metal–NHC chelation, coordination assembly,and covalent bonding. Additionally, we compile the diverse applications of these cages within catalytic processes and molecular recognition. Lastly, we shed light on the current limitations of synthesis and outline future trends in the development of NHCbased cages.

关键词： N-heterocyclic carbene molecular cages supramolecular chemistry synthetic strategies applications

The adsorption behavior of metals in aqueous solution by microplastics effected by UV radiation

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Journal of Environmental Sciences 2020年第1期32卷 272-280页

作者： qiongjie Wang Yong Zhang Xiaoxue Wangjin Yulai Wang Guanhua Meng Yihua Chen School of Energy and Environment Anhui University of Technology

Microplastics are considered as the carrier to heavy metals in the *** the sorption ability of microplastics influenced by photo-aging is remaining *** the present study,the sorption of two kinds of metal ions(Cu^2+ and Zn^2+)in the aqueous solution by both the virgin and aged microplastics was *** terephthalate(PET)debris,one of the typical kinds of microplastics was chosen in this ***-aging of microplastics in environment was simulated using UV radiation in the *** analysis indicated that the aged microplastics had higher adsorption capacity of heavy metals than original *** could be related to the increased surface area and oxygen containing function appeared in the surface of aged microplastics after UV *** prolonging the time of radiation,the enhanced adsorption capacities of microplastics appeared for Cu^2+ and Zn^2+.These results showed a great interaction between the aging degree of plastics and sorption capacity to heavy ***,external conditions including temperature and pH value were also showed great influence to the adsorption behavior.

关键词： UV radiation Microplastics Adsorption Metal ions