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Diagnosis based on electromagnetic navigational bronchoscopyguided biopsied peripheral lung lesions in a 10-year-old girl:A case report

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World Journal of Clinical Cases 2023年第15期11卷 3651-3657页

作者： Fan-Zheng Meng qiong-hua chen Man Gao Li'e Zeng Jie-Ru Lin Jing-Yang Zheng Department of Pediatrics The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Respiratory Medicine The Third Clinical Medical CollegeFujian Medical UniversityQuanzhou Women's and Children's HospitalQuanzhou 362000Fujian ProvinceChina Department of Respiratory Medicine Quanzhou Women's and Children's HospitalQuanzhou 362000Fujian ProvinceChina Department of Respiratory Medicine Quanzhou Women's and Children's HospitalThe Third Clinical Medical CollegeFujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

BACKGROUND Electromagnetic navigational bronchoscopy(ENB)is an emerging diagnostic tool that enables practitioners to biopsy peripheral lung tissues that were previously only accessible under computed tomography(CT)***,few studies have investigated ENB use in ***,we report a case of a 10-yearold girl with peripheral lung lesions who complained of a 7-d persistent *** was diagnosed with Streptococcus parasanguinis infection based on findings obtained using ENB-guided transbronchial lung biopsy(TBLB).CASE SUMMARY A 10-year-old girl presented with constitutional symptoms of cough and fever of 7 days’*** CT scans detected peripheral lung lesions and no endobronchial *** performed under the guidance of an ENB Lungpro navigation system was safe,well-tolerated,and effective for biopsying peripheral lung *** of biopsied samples indicated the patient had a pulmonary Streptococcus parasanguinis infection,which was treated with antibiotics instead of more invasive treatment *** patient’s symptoms resolved after she received a 3-wk course of oral *** of pretreatment and post-treatment CT scans revealed absorption of some lung lesions within 7 mo of hospital *** ENB-guided TBLB biopsying of peripheral lung lesions in this child is a safe,well-tolerated,and effective alternative to conventional interventions.

关键词： Electromagnetic navigational bronchoscopy Lungpro Transbronchial lung biopsy Child Diagnosis Case report

Boron shielding design for neutron and gamma detectors of a pulsed neutron tool

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Nuclear Science and Techniques 2025年第1期36卷 115-126页

作者： Xin-Yang Wang Jun-Yan chen qiong Zhang University of Electronic Science and Technology of China Chengdu 611731China

Shielding materials are critical for downhole pulsed neutron tool design because they directly influence the accuracy of formation measurements.A well-designed shield configuration ensures that the response of the tool is maximally representative of the formation without being affected by the tool and borehole *** study investigated the effects of boron-containing materials on neutron and gamma detectors based on a newly designed logging-while-drilling tool that is currently undergoing *** the boron content increased,the ability to absorb thermal neutrons increased *** simulation,it was proven that boron carbide(B_(4)C)can be used as an effective boron shielding material for thermal neutrons,and is therefore employed in this *** shield against thermal neutrons migrating from the mud pipes,the optimal shielding thicknesses for the near-and far-neutron detectors were determined to be 5 and 4 *** a porosity of 25 p.u.,near-neutron sensitivity exhibited a 5.6%***,to shield the capture gamma generated by thermal neutrons once they enter the tool from the mud pipe and formation,internal and external shields for the gamma detector were *** results show that the internal shield requires a boron content of 75%,whereas the external shield has a thickness of 14.2 mm thickness and a boron content of 25%to minimize the tool effect.

关键词： Nuclear well logging Pulsed neutron tool Boron shielding

Engineering atomic Rb-N configurations to tune radical pathways for highly selective photocatalytic H_(2)O_(2) synthesis coupled with biomass valorization

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Journal of Energy Chemistry 2025年第1期100卷 215-225页

作者： Jiaye Li Shuang Pan Yihuang chen qiong Liu College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou 325035ZhejiangChina Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology(China) Institute of AnalysisGuangdong Academy of Sciences(China National Analytical CenterGuangzhou)Guangzhou 510070GuangdongChina

Photocatalytic oxygen reduction for hydrogen peroxide(H_(2)O_(2))synthesis presents a green and costeffective production ***,achieving highly selective H_(2)O_(2)synthesis remains challenging,necessitating precise control over free radical reaction pathways and minimizing undesirable oxidative ***,we report for the visible light-driven simultaneous co-photocatalytic reduction of O2to H_(2)O_(2)and oxidation of biomass using the atomic rubidium-nitride modified carbon nitride(CNRb).The optimized CNRb catalyst demonstrates a record photoreduction rate of 8.01 mM h^(-1)for H_(2)O_(2)generation and photooxidation rate of 3.75 mM h^(-1)for furfuryl alcohol to furoic acid,achieving a remarkable solar-to-chemical conversion(SCC)efficiency of up to 2.27%.Experimental characterizations and DFT calculation disclosed that the introducing atomic Rb–N configurations allows for the high-selective generation of superoxide radicals while suppressing hydroxyl free radical *** is because the Rb–N serves as the new alternative site to perceive a stronger connection position for O2adsorption and reinforce the capability to extract protons,thereby triggering a high selective redox product *** study holds great potential in precisely regulating reactive radical processes at the atomic level,thereby paving the way for efficient synthesis of H_(2)O_(2)coupled with biomass valorization.

关键词： Atomic economy Radical pathway regulation Photocatalytic H_(2)O_(2)synthesis Rubidium atom coordination Biomass valorization

Impact of Spinal Manipulative Therapy on Brain Function and Pain Alleviation in Lumbar Disc Herniation:A Resting-State fMRI Study

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Chinese Journal of Integrative Medicine 2025年第2期31卷 108-117页

作者： ZHOU Xing-chen WU Shuang WANG Kai-zheng chen Long-hao WEI Zi-cheng LI Tao hua Zi-han XIA qiong LYU Zhi-zhen LYU Li-jiang Department of Spine The Third Affiliated Hospital of Zhejiang Chinese Medicine UniversityHangzhou(310053)China Department of Spine The Third School of Clinical MedicineZhejiang Chinese Medicine UniversityHangzhou(310053)China Research Institute of Tuina(Spinal Disease) Zhejiang Chinese Medicine UniversityHangzhou(310053)China

Objective:To elucidate how spinal manipulative therapy(SMT)exerts its analgesic effects through regulating brain function in lumbar disc herniation(LDH)patients by utilizing resting-state functional magnetic resonance imaging(rs-f MRI).Methods:From September 2021 to September 2023,we enrolled LDH patients(LDH group,n=31)and age-and sex-matched healthy controls(HCs,n=28).LDH group underwent rs-f MRI at 2 distinct time points(TPs):prior to the initiation of SMT(TP1)and subsequent to the completion of the SMT sessions(TP2).SMT was administered once every other day for 30 min per session,totally 14 treatment sessions over a span of 4 *** did not receive SMT treatment and underwent only one f MRI ***,participants in LDH group completed clinical questionnaires on pain using the Visual Analog Scale(VAS)and the Japanese Orthopedic Association(JOA)score,whereas HCs did not undergo clinical scale *** effects on the brain were jointly characterized using the amplitude of low-frequency fluctuations(ALFF)and regional homogeneity(Re Ho).Correlation analyses were conducted between specific brain regions and clinical ***:Following SMT treatment,pain symptoms in LDH patients were notably alleviated and accompanied by evident activation of effects in the *** comparison to TP1,TP2 exhibited the most significant increase in ALFF values for Temporal_Sup_R and the most notable decrease in ALFF values for Paracentral_Lobule_L(voxelwise P30;FDR correction).Additionally,the most substantial enhancement in Re Ho values was observed for the Cuneus_R,while the most prominent reduction was noted for the Olfactory_R(voxelwise P30;FDR correction).Moreover,a comparative analysis revealed that,in contrast to HCs,LDH patients at TP1 exhibited the most significant increase in ALFF values for Temporal_Pole_Sup_L and the most notable decrease in ALFF values for Frontal_Mid_L(voxelwise P30;FDR correction).Fur

关键词： functional magnetic resonance imaging lumbar disc herniation spinal manipulative therapy pain

Elastogram:Physics,Clinical Applications,and Risks

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Maternal-Fetal Medicine 2019年第2期1卷 113-122页

作者： Jing Lu Min chen qiong-hua chen Qin Wu Jin-Na Jiang Tak-Yeung Leung Department of Obstetrics&Gynecology The First Affiliated Hospital of XiamenUniversityXiamen 361000China Department of Obstetrics&Gynecology The Chinese Universityof Hong KongHong Kong 999077China Department of Fetal Medicine and Prenatal Diagnosis TheThird Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510000China

The tissue stiffness is always an interesting issue to ***,it is assessed by the manual palpation,and this now can be measured by the ultrasound-based *** basic physics is based on Young's modulus through the Hooke's law:E=S/e,where the Young's modulus(E)equals to the stress applied to the object(S)divided by the generated strain(e).With the rapid advancement of technology,the elastography has evolved from quasi-static elastography(ie,strain elastography)to dynamic elastography(i,e,shear wave elastography).The key differentiation of these two categories roots in the stimuli applied,namely mechanical or acoustic radiation force,and the response of the soft *** strain elastography requires the operator to compress and decompress the tissue manually and the motion of the tissue during the stimuli is tracked to calculate the strain to reflect the tissue *** strain elastography is operator-dependent,shear wave elastography is *** shear wave elastography,the tissue is stimulated by the acoustic radiation force which can generate shear wave traveling through the tissue *** shear wave propagation speed(Vs)is related to the shear modulus(μ)of the medium:μ=pVs^(2),where p is the density of the tissue and assumed to be a constant as 1000 kg/m^(3).In the incompressible biological tissue,the Young's modulus is approximately three times the shear modulus(E≈3μ).So the quantitative measurements of the tissue stiffness can be attained by shear wave *** clinical application of elastography and its diagnostic capability has been *** knowledge of the basic physics of the various type of elastography facilitates the effective use of *** review presented the clinical application and the risks of different types of elastography.

关键词： Elasticity Elasticity imaging techniques Shear wave elastography Strain elastography Stiffness

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Thermal effects on the strain rate-dependent behavior of highly compacted GMZ01 bentonite

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Journal of Rock Mechanics and Geotechnical Engineering 2025年第1期17卷 453-464页

作者： Pengju Qin Weimin Ye qiong Wang Yonggui chen College of Civil Engineering Taiyuan University of TechnologyTaiyuan030024China Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai200092China Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education Tongji UniversityShanghai200092China

Investigation of thermal effects on the strain rate-dependent properties of compacted bentonite is crucial for the long-term safety assessment of deep geological repository for disposal of high-level radioactive *** the present work,cylindrical GMZ01 bentonite specimens were compacted with suction-controlled by the vapor equilibrium ***,a series of temperature-and suction-controlled stepwise constant rate of strain(CRS)tests was performed and the rate-dependent compressibility behavior of the highly compacted GMZ01 bentonite was *** plastic compressibility parameterλ,the elastic compressibility parameterκ,the yield stress p0,as well as the viscous parameterαwere *** indicate thatλ,κandαdecrease and p0 increases as suction *** heating,parametersλ,αand p0 *** is also found that p0 increases linearly with increasing CRS in a double-logarithm *** on the experimental results,a viscosity parameterα(s,T)was fitted to capture the effects of suction s and temperature T on the relationship between yield stress and strain ***,an elastic-thermo-viscoplastic model for unsaturated soils was developed to describe the thermal effects on the rate-dependent behavior of highly compacted GMZ01 *** showed that the calculated results agreed well to the measured ones.

关键词： Highly compacted bentonite Rate-dependent behavior Constant rate of strain Temperature Elastic-thermo-viscoplastic model

Aspirin-triggered Lipoxin A4 Inhibits LPS-Induced IL-6,IL-8 and MCP-1 Expression in Human Endometriotic Stromal Cells

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Aspirin-triggered Lipoxin A4 Inhibits LPS-Induced IL-6,IL-8 ...

Growth of CeCo-MOF in dendritic mesoporous organosilica as highly efficient antioxidant for enhanced thermal stability of silicone rubber

生命的分子机器及其调控网络——2012年全国生物化学与分子生物学学术大会

作者： Wei-Dong Zhou Shuo chen Rong-Feng Wu Hui-Ming Yang qiong-hua chen Qing-Xi chen State Key Laboratory of Cellular Stress Biology School of Life SciencesXiamen University Medical College of Xiamen University Department of Obstetrics and Gynecology Xiamen First Hospital affiliated to Xiamen University

Endometriosis(EM) is a common and refractory gynecological *** the fact that the underlying mechanisms responsible for EM remain unclear,EM has been widely accepted as an inflammation-related ***,lipoxins,the endogenous"breaking signals" in inflammation,were found to suppress the development of *** this study,the immunohistochemistry result showed that protein expression of lipoxin A4 receptor(ALXR) in endometrium with endometriosis were significant higher than in

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Chinese Chemical Letters 2025年第1期36卷 381-386页

作者： Guizhi Zhu Junrui Tan Longfei Tan qiong Wu Xiangling Ren Changhui Fu Zhihui chen Xianwei Meng State Key Laboratory of Cryogenic Science and Technology Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China School of Materials Science and Engineering Changzhou UniversityChangzhou 213164China

High-efficient rubber antioxidants for enhanced heat resistance without compromising mechanical properties remain an enormous and long-term challenge for the rubber ***,we employed the in-situ growth of Ce-doped Co-metal-organic framework(Ce Co-MOF)in dendritic mesoporous organosilica nanoparticles(DMONs@Ce Co-MOF,denoted as DCCM)to prepare a novel antioxidant that exhibit outstanding thermal *** mesoporous organosilica nanoparticles(DMONs)effectively alleviated the incompatibility of Ce Co-MOF in the polymer matrix,and the effective scavenging of free radicals was attributed to the various oxidation states of metal ions in Ce ***,by adding only0.5 phr(parts per hundred of rubber)of DMONs@Ce Co-MOF to silicone rubber,(SR),the retention rate of tensile strength increased from 37.3%to 61.6%after aging 72 h at 250℃,and the retention rate of elongation at break of DCCM/SR1 composites reached 68%,which was 5.43 times of *** strategy of anchoring MOFs on the surface of silica also provides a viable method for preparing effective compound functionalized rubber antioxidant.

关键词： Mesoporous organosilica nanoparticles Silicone rubber Metal-organic framework Antioxidants Thermal stability Thermal oxidative degradation

Crocodile Choline Induces Apoptosis of Human Gastric Cancer BGC823 Cells

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Crocodile Choline Induces Apoptosis of Human Gastric Cancer ...