检索结果-南通市图书馆

Values of a novel pyroptosis-related genetic signature in predicting outcome and immune status of pancreatic ductal adenocarcinoma

引用

Gastroenterology Report 2022年第1期10卷 476-489页

作者： Xiang xu Jia-Hua Liang Jian-Hui Li qiong-cong xu Xiao-Yu Yin Department of Pancreato-Biliary Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongP.R.China

Background Pyroptosis is an emerging form of programmed cell death associated with progression in ***,there are few studies reporting on the association between pancreatic ductal adenocarcinoma(PDAC)and ***,we aimed to construct a pyroptosis-related genetic signature to predict the clinical outcome and immune status in PDAC *** RNA-seq data of 176 PDAC patients from The Cancer Genome Atlas(TCGA)and 167 PDAC patients from the Genotype-Tissue Expression Project were analysed for pyroptosis-related differentially expressed genes(DEGs)between PDAC and normal *** risk signature of DEGs was analysed using the least absolute shrinkage and selection operator(LASSO)Cox regression analysis and its accuracy was validated in the Gene Expression Omnibus(GEO)cohort(n=190).Functional enrichment analyses were performed to explore the mechanisms of the *** immune characteristics were evaluated using single-sample gene set enrichment analysis and ESTIMATE algorithms for each *** A nine-gene risk signature was generated from LASSO Cox regression analysis and classified PDAC patients into either a high-or low-risk group according to the median risk *** high-risk group had significantly shorter overall survival than the low-risk group and it was verified in the external GEO database.A nomogrambased on the risk signature was constructed and showed an ideal prediction *** enrichment analyses revealed that pyroptosis might regulate the tumor immune microenvironment in *** infiltration evaluation suggested that immune status was more activated in the low-risk group than in the high-risk *** The risk signature encompassing nine pyroptosis-related genes may be a prognostic marker for *** might affect the prognosis of PDAC patients via regulating the tumor immune microenvironment.

关键词： pancreatic ductal adenocarcinoma pyroptosis prognosis immune

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A phenology-based vegetation index for improving ratoon rice mapping using harmonized Landsat and Sentinel-2 data

引用

Journal of Integrative Agriculture 2024年第4期23卷 1164-1178页

作者： Yunping Chen Jie Hu Zhiwen Cai Jingya Yang Wei Zhou qiong Hu cong Wang Liangzhi You Baodong xu Macro Agriculture Research Institute College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan 430070China College of Resources and Environment Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Agricultural Remote Sensing Ministry of Agriculture and Rural Affairs/Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Key Laboratory for Geographical Process Analysis&Simulation of Hubei Province/College of Urban and Environmental Sciences Central China Normal UniversityWuhan 430079China International Food Policy Research Institute NWWashingtonD.C.20005USA

Ratoon rice,which refers to a second harvest of rice obtained from the regenerated tillers originating from the stubble of the first harvested crop,plays an important role in both food security and agroecology while requiring minimal agricultural ***,accurately identifying ratoon rice crops is challenging due to the similarity of its spectral features with other rice cropping systems(e.g.,double rice).Moreover,images with a high spatiotemporal resolution are essential since ratoon rice is generally cultivated in fragmented croplands within regions that frequently exhibit cloudy and rainy *** this study,taking Qichun County in Hubei Province,China as an example,we developed a new phenology-based ratoon rice vegetation index(PRVI)for the purpose of ratoon rice mapping at a 30 m spatial resolution using a robust time series generated from Harmonized Landsat and Sentinel-2(HLS)*** PRVI that incorporated the red,near-infrared,and shortwave infrared 1 bands was developed based on the analysis of spectro-phenological separability and feature *** on actual field samples,the performance of the PRVI for ratoon rice mapping was carefully evaluated by comparing it to several vegetation indices,including normalized difference vegetation index(NDVI),enhanced vegetation index(EVI)and land surface water index(LSWI).The results suggested that the PRVI could sufficiently capture the specific characteristics of ratoon rice,leading to a favorable separability between ratoon rice and other land cover ***,the PRVI showed the best performance for identifying ratoon rice in the phenological phases characterized by grain filling and harvesting to tillering of the ratoon crop(GHS-TS2),indicating that only several images are required to obtain an accurate ratoon rice ***,the PRVI performed better than NDVI,EVI,LSWI and their combination at the GHS-TS2 stages,with producer's accuracy and user's accuracy of 92.22 and 89.30%,respectively

关键词： ratoon rice phenology-based ratoon rice vegetation index(PRVI) phenological phase feature selection Harmonized Landsat Sentinel-2 data

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A risk assessment method considering risk attributes and work safety informational needs and its application

引用

Chinese Journal of Chemical Engineering 2024年第4期68卷 253-262页

作者： cong Luo Yunsheng Zhao Ke xu School of Political Science and Public Administration Shandong UniversityQingdao 266200China Faculty of Engineering China University of GeosciencesWuhan 430074China Department of Emergency Management of Hubei Province Wuhan 430064China

The technological revolution has spawned a new generation of industrial systems,but it has also put forward higher requirements for safety management accuracy,timeliness,and *** assessment needs to evolve to address the existing and future challenges by considering the new demands and advancements in safety *** study aims to propose a systematic and comprehensive risk assessment method to meet the needs of process system safety *** methodology first incorporates possibility,severity,and dynamicity(PSD)to structure the“51X”evaluation indicator system,including the inherent,management,and disturbance risk ***,the four-tier(risk point-unit-enterprise-region)risk assessment(RA)mathematical model has been established to consider supervision *** in conclusion,the application of the PSD-RA method in ammonia refrigeration workshop cases and safety risk monitoring systems is presented to illustrate the feasibility and effectiveness of the proposed PSD-RA method in safety *** findings show that the PSD-RA method can be well integrated with the needs of safety work informatization,which is also helpful for implementing the enterprise's safety work responsibility and the government's safety supervision responsibility.

关键词： Risk assessment Safey “51X”evaluation indicator system Four-tier risk assessment model Risk attributes Process system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Simulation study on the security of consensus algorithms in DAG-based distributed ledger

引用

Frontiers of Computer Science 2024年第3期18卷 171-182页

作者： Shuzhe LI Hongwei xu qiong LI Qi HAN Faculty of Computing Harbin Institute of TechnologyHarbin 150001China

Due to the advantages of high volume of transactions and low resource consumption,Directed Acyclic Graph(DAG)-based Distributed Ledger Technology(DLT)has been considered a possible next-generation alternative to ***,the security of the DAG-based system has yet to be comprehensively *** at verifying and evaluating the security of DAG-based DLT,we develop a Multi-Agent based IOTA Simulation platform called *** MAIOTASim,we model honest and malicious nodes and simulate the configurable network environment,including network topology and *** double-spending attack is a particular security issue related to *** perform the security verification of the consensus algorithms under multiple double-spending attack *** simulations show that the consensus algorithms can resist the parasite chain attack and partially resist the splitting attack,but they are ineffective under the large weight *** take the cumulative weight difference of transactions as the evaluation criterion and analyze the effect of different consensus algorithms with parameters under each attack ***,MAIOTASim enables users to perform largescale simulations with multiple nodes and tens of thousands of transactions more efficiently than state-of-the-art ones.

关键词： distributed ledger IOTA Multi-Agent system simulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tighter sum uncertainty relations via(α,β,γ)weighted Wigner–Yanase–Dyson skew information

引用

Communications in Theoretical Physics 2024年第3期76卷 91-99页

作者： cong xu Zhaoqi Wu Shao-Ming Fei School of Mathematical Sciences Capital Normal UniversityBeijing 100048China Department of Mathematics Nanchang UniversityNanchang 330031China Max-Planck-Institute for Mathematics in the Sciences 04103 LeipzigGermany

We establish tighter uncertainty relations for arbitrary finite observables via(α,β,γ)weighted Wigner–Yanase–Dyson((α,β,γ)WWYD)skew *** results are also applicable to the(α,γ)weighted Wigner–Yanase–Dyson((α,γ)WWYD)skew information and the weighted Wigner–Yanase–Dyson(WWYD)skew *** also present tighter lower bounds for quantum channels and unitary channels via(α,β,γ)modified weighted Wigner–Yanase–Dyson((α,β,γ)MWWYD)skew *** examples are provided to illustrate the tightness of our uncertainty relations.

关键词： quantum channels (α,β,γ)WWYD skew information (α,β,γ)MWWYD skew information uncertainty relations

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A lightweight false alarm suppression method in heterogeneous change detection

引用

Journal of Systems Engineering and Electronics 2024年第4期35卷 899-905页

作者： xu cong HE Zishu LIU Haicheng School of Electronic and Information Engineering Heilongjiang Institute of EngineeringHarbin 150026China School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

Overlooking the issue of false alarm suppression in heterogeneous change detection leads to inferior detection *** paper proposes a method to handle false alarms in heterogeneous change detection.A lightweight network of two channels is bulit based on the combination of convolutional neural network(CNN)and graph convolutional network(GCN).CNNs learn feature difference maps of multitemporal images,and attention modules adaptively fuse CNN-based and graph-based features for different *** with a new kernel filter adaptively distinguish between nodes with the same and those with different labels,generating change *** evaluation on two datasets validates the efficacy of the pro-posed method in addressing false alarms.

关键词： convolutional neural network(CNN) graph convolu-tional network(GCN) heterogeneous change detection lightweight false alarm suppression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The prediction of projectile-target intersection for moving tank based on adaptive robust constraint-following control and interval uncertainty analysis

引用

Defence Technology（防务技术） 2024年第1期31卷 351-363页

作者： cong Li Xiuye Wang Yuze Ma Fengjie xu Guolai Yang The School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing290014PR China Inner Mongolia North Heavy Industries Co. Ltd.Baotou014033PR China Nanjing Chenguang Group Co. Ltd.Nanjing210006PR China

To improve the hit probability of tank at high speed,a prediction method of projectile-target intersection based on adaptive robust constraint-following control and interval uncertainty analysis is *** method proposed provides a novel way to predict the impact point of projectile for moving ***,bidirectional stability constraints and stability constraint-following error are constructed using the Udwadia-Kalaba theory,and an adaptive robust constraint-following controller is designed considering ***,the exterior ballistic ordinary differential equation with uncertainties is integrated into the controller,and the pointing control of stability system is extended to the impact-point control of ***,based on the interval uncertainty analysis method combining Chebyshev polynomial expansion and affine arithmetic,a prediction method of projectile-target intersection is ***,the co-simulation experiment is performed by establishing the multi-body system dynamic model of tank and mathematical model of control *** results demonstrate that the prediction method of projectile-target intersection based on uncertainty analysis can effectively decrease the uncertainties of system,improve the prediction accuracy,and increase the hit *** adaptive robust constraint-following control can effectively restrain the uncertainties caused by road excitation and model error.

关键词： Tank stability control Constraint-following Adaptive robust control Uncertainty analysis Prediction of projectile-target intersection

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Crack mechanism of ground fissures in loess layer of Fenwei Basin, China

引用

Journal of Mountain Science 2024年第5期21卷 1683-1696页

作者： LI cong LU Quanzhong WANG Feiyong LUO Wenchao xu Qiang School of Geological Engineering and Geomatics Chang’an UniversityXi’an 710054China Key Laboratory of Western Mineral Resources and Geological Engineering Ministry of EducationXi’an 710054China Observation and Research Station of Ground Fissure and Land Subsidence Ministry of Natural ResourcesXi’an 710054China School of Engineering and Technology China University of GeosciencesBeijing 100083China

The Fenwei Basin, covered by loess, experiences severe ground fissure disasters. These disasters disrupt the continuity of the loess and pose significant threats to engineering construction safety along transportation routes. Nevertheless, the crack characteristics and the influence zone of ground fissures in the loess layer remain inadequately investigated. To effectively prevent and control ground fissure disasters, physical model tests and the PFC(particle flow code) numerical simulation method are used to investigate the crack mechanism of buried ground fissures in the loess layer. The results show that there are two main cracks in the layer profile, which have a Y-shape morphology. As the dip angle of the preset cracks increased from 60° to 90°, the main deformation zone at the surface gradually shifted towards the footwall. The process of crack propagation from depth to surface is divided into five stages. Additionally, the results confirm the accuracy of the width of the rupture zone d2in the footwall calculated by the cantilever beam theory. These findings can offer theoretical guidance for determining the avoidance distance of ground fissures in loess regions, as well as for implementing disaster prevention and corresponding control measures for various stages of buried ground fissure propagation.

关键词： Ground fissure Fenwei Basin Physical model test Particle flow code Crack propagation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Experimental investigation on effective aerosol scavenging using different spray configurations with pre-injection of water mist for Fukushima Daiichi decommissioning

引用

Nuclear Science and Techniques 2024年第5期35卷 154-172页

作者： Rui-cong xu Avadhesh Kumar Sharma Erdal Ozdemir Shuichiro Miwa Shunichi Suzuki Department of Nuclear Engineering and Management The University of Tokyo7‑3‑1 HongoBunkyo‑KuTokyo 113‑8656Japan Nuclear Professional School The University of Tokyo2‑2

During the decommissioning of the Fukushima Daiichi nuclear power plant,it is important to consider the retrieval of resolidified debris both in air and underwater *** the subsequent retrieval of debris from the reactor building,the resolidified debris must be cut into smaller pieces using various cutting *** the cutting process,aerosol particles are expected to be generated at the submicron *** has been noted that such aerosols sizing within the Greenfield gap(0.1-1μm)are difficult to remove effectively using traditional spraying ***,to improve the aerosol removal efficiency of the spray system,a new aerosol agglomeration method was recently proposed,which involves injecting water mist to enlarge the sizes of the aerosol particles before removing them using water *** this study,a series of experiments were performed to clarify the proper spray configurations for effective aerosol scavenging and to improve the performance of the water *** experimental results showed that the spray flow rate and droplet characteristics are important factors for the aerosol-scavenging efficiency and performance of the water *** results obtained from this study will be helpful for the optimization of the spray system design for effective aerosol scavenging during the decommissioning of the Fukushima Daiichi plant.

关键词： Fukushima Daiichi decommissioning Aerosol scavenging Multiphase flow Spray system Aerosol-mist agglomeration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis and characterization of iron clusters with an icosahedral [Fe@Fe12]16+ Core

引用

National Science Review 2024年第4期11卷 123-129页

作者： Gan xu Yun-Shu Cui xue-Lian Jiang cong-Qiao xu Jun Li xu-Dong Chen Jiangsu Collaborative Innovation Center of Biomedical Functional Materials and Jiangsu Key Laboratory of New Power Batteries School of Chemistry and Materials Science Nanjing Normal University Department of Chemistry and Guangdong Provincial Key Laboratory of Catalytic Chemistry Southern University of Science and Technology Department of Chemistry and Engineering Research Center of Advanced Rare-Earth Materials of Ministry of Education Tsinghua University State Key Laboratory of Coordination Chemistry Nanjing University

Iron-metal clusters are crucial in a variety of critical biological and material systems,including metalloenzymes,catalysts,and magnetic storage ***,a synthetic high-nuclear iron cluster has been absent due to the extreme difficulty in stabilizing species with direct iron-iron *** this work,we have synthesized,crystallized,and characterized a（Tp*）4W4S12(Fe@Fe12) cluster(Tp*=tris（3,5-dimethyl-1-pyrazolyl）borate（1-）),which features a rare trideca-nuclear,icosahedral[Fe@Fe12] cluster core with direct multicenter iron-iron bonding between the interstitial iron（Fei） and peripheral irons（Fep）,as well as Fep…Fepferromagnetic *** chemistry studies reveal that the stability of the cluster arises from the 18-electron shell-closing of the [Fe@Fe12]16+core,assisted by its bonding interactions with the peripheral tridentate [（Tp*）WS3]4-ligands which possess both S→Fe donation and spin-polarized Fe-Wσ *** ground-state electron spin is theoretically predicted to be S=32/2 for the *** existence of low oxidation-state（OS～+1.23） iron in this compound may find interesting applications in magnetic storage,spintronics,redox chemistry,and cluster catalysis.

关键词： Fe13 cluster iron-sulfur cluster low-valence iron iron−iron bond high spin complex

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：