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儿童鼻窦炎鼻负压置换治疗中沟通技巧结合健康教育的应用效果

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中国医药指南 2024年第19期22卷 134-136页

作者：程琼娥泉州市第一医院城东分院儿科泉州362000

目的探究在儿童鼻窦炎鼻负压置换治疗中应用沟通技巧结合健康教育的意义。方法采取随机数字表法从泉州市第一医院城东分院抽取2023年4月至2024年2月收治的80例儿童鼻窦炎患者分为两组(对照组与观察组),其中对照组给予健康教育,观察组... 详细信息

目的探究在儿童鼻窦炎鼻负压置换治疗中应用沟通技巧结合健康教育的意义。方法采取随机数字表法从泉州市第一医院城东分院抽取2023年4月至2024年2月收治的80例儿童鼻窦炎患者分为两组(对照组与观察组),其中对照组给予健康教育,观察组在前组基础上,加用沟通技巧,干预20 d后比较两组患儿干预前后哭闹次数/住院时间、依从性评分、睡眠质量、心理情绪、舒适度评分。结果干预20 d后,观察组哭闹次数(1.34±0.06)次、住院时间(3.91±0.26)d低于对照组(5.03±1.63)次、(8.46±0.32)d;观察组依从性评分(8.46±2.01)分高于对照组(6.30±2.01)分;观察组睡眠质量评分(2.61±0.94)分低于对照组(8.49±2.55);观察组心理情绪评分(38.30±1.70)分低于对照组(48.56±2.97)分;观察组舒适度评分(104.64±4.27)分高于对照组(80.91±5.48)分(均P <0.05)。结论健康教育联合沟通技巧,可有效改善鼻负压置换治疗中患儿的睡眠质量、舒适度及负性情绪,降低患儿住院时间及哭闹次数,提高患儿治疗依从性,具有临床应用意义。

关键词：儿童鼻窦炎鼻负压置换治疗沟通技巧健康教育

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偏心不耦合系数对爆破裂隙影响的数值模拟

广西大学学报（自然科学版） 2024年第2期49卷 259-268页

作者：成琼张延年屈林永解明侠程扬方逵宾沈阳建筑大学土木工程学院辽宁沈阳110000 中冶天工集团天津有限公司天津300300 中国建筑东北设计研究院有限公司辽宁沈阳110000 中建东设岩土工程有限公司辽宁沈阳110000

为了探究偏心不耦合爆破岩石的最优不耦合系数,建立6组单孔二维ANSYS/LS-DYNA模型,分析PK本构岩石在偏心不耦合爆破荷载作用下的损伤效应。结果表明:①随着偏心不耦合系数的增加,不耦合侧破碎区半径呈现先显著减小再缓慢减小的趋势,而... 详细信息

为了探究偏心不耦合爆破岩石的最优不耦合系数,建立6组单孔二维ANSYS/LS-DYNA模型,分析PK本构岩石在偏心不耦合爆破荷载作用下的损伤效应。结果表明:①随着偏心不耦合系数的增加,不耦合侧破碎区半径呈现先显著减小再缓慢减小的趋势,而耦合侧为先快速增大再缓慢减小;不耦合侧裂隙延伸长度呈现先略减小而后缓慢增加最后显著降低的趋势,耦合侧则基本不变;不耦合侧爆心距20 cm处质点振动峰值速度呈显著增加趋势;②当不耦合系数不变时,岩石抗压强度越大裂隙延伸长度越长,反之越短。当不耦合系数k=1.7时,不同抗压强度岩石在偏心爆破荷载作用下实现不耦合侧破碎区半径最小而耦合侧较大,不耦合侧裂隙少且耦合侧较发育,有效减小非爆破区岩石爆破效应,为最优偏心不耦合系数。

关键词： PK本构模型偏心不耦合装药爆破损伤振动峰值速度数值模拟

具有黏液样变的高分化/去分化脂肪肉瘤34例临床病理及分子遗传学特征分析

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中华病理学杂志 2024年第2期53卷 168-173页

作者：薛霜刘秋雨缑向楠赵跃武成琼孔令非河南省人民医院郑州大学人民医院病理科郑州450003 解放军总医院第一医学中心病理科北京100853

目的探讨具有黏液样变的高分化/去分化脂肪肉瘤临床病理及分子遗传学特征,并与具有相似形态的黏液纤维肉瘤相鉴别。方法收集河南省人民医院及解放军总医院第一医学中心2015年1月至2023年3月确诊黏液样变脂肪肉瘤29例、黏液纤维肉瘤5例,... 详细信息

目的探讨具有黏液样变的高分化/去分化脂肪肉瘤临床病理及分子遗传学特征,并与具有相似形态的黏液纤维肉瘤相鉴别。方法收集河南省人民医院及解放军总医院第一医学中心2015年1月至2023年3月确诊黏液样变脂肪肉瘤29例、黏液纤维肉瘤5例,采用免疫组织化学、荧光原位杂交(FISH)检测相关指标情况,并复习文献。结果34例患者中男性24例,女性10例,年龄41~73岁;发病部位包括腹膜后(17例)、腹腔(9例)、下肢(5例)、阴囊(1例)、上肢(1例)和腋下(1例)。高分化脂肪肉瘤以脂肪瘤样型多见(12例);去分化脂肪肉瘤的去分化成分包括低级别(13例)和高级别(2例)形态,呈低至高级别黏液纤维肉瘤样、隆突性皮肤纤维肉瘤样、低级别纤维肉瘤结构。29例脂肪肉瘤均具有不同比例的黏液样形态,16例伴多少不等肿瘤性坏死。黏液样形态表现为黏液样脂肪肉瘤样,呈分叶状生长,特征性的纤细、分支状毛细血管网,类似于鸡爪样形态,富含黏液的间质和肺水肿样形态,肿瘤细胞呈梭形及卵圆形,伴多少不等多空泡状脂肪母细胞。FISH法检测MDM2基因显示成簇扩增(29/29),DDIT3分离探针均未发生断裂,但显示成簇扩增(24/29);黏液纤维肉瘤中1例存在DDIT3分离探针簇状扩增(1/5),无基因断裂,且MDM2基因无扩增。结论具有黏液样变的高分化/去分化脂肪肉瘤以腹膜后和腹腔最为多见,大多呈DDIT3分离探针扩增,但该扩增现象并非脂肪肉瘤特异性表现。对于穿刺标本或极少数发生在四肢的肿瘤,当组织学具有黏液间质、黏液样脂肪肉瘤样形态时,应避免误诊为黏液样脂肪肉瘤或其他具有黏液样形态的非脂肪源性肿瘤。

关键词：软组织肿瘤脂肪肉瘤,黏液样基因扩增

Papillary thyroid carcinoma occurring with undifferentiated pleomorphic sarcoma: A case report

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World Journal of Clinical Cases 2022年第23期10卷 8336-8343页

作者： Yu-Li Lee Ya-qiong cheng Chen-Fang Zhu Hai-Zhong Huo Department of General Surgery Shanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineDiscipline Construction Research Center of China Hospital Development InstituteShanghai Jiao Tong UniversityShanghai 200011China

BACKGROUND Papillary thyroid cancer(PTC)is the most common malignant tumor of the ***,the coexistence of PTC and sarcoma in one patient is *** this article,we report the case of a patient who presented with both PTC and undifferentiated pleomorphic sarcoma(UPS),which has not been previously reported in the online Medline database(PubMed).CASE SUMMARY A 71-year-old man was admitted to our hospital for a mass on the right side of his neck for one month,which rapidly enlarged within 2 wk with distending *** patient was diagnosed with a thyroid malignancy by fine-needle aspiration and underwent total thyroidectomy and bilateral central lymph node *** and immunohistochemistry revealed features of both PTC and *** thyroid cancer 8 gene detection kit results showed BRAF and telomerase reverse transcriptase *** disease progressed rapidly,and the patient died four months after surgery from extensive lung *** Our report highlights the patient’s pathological characteristics and related genetic *** to the rapid development and poor prognosis of cooccurring PTC and sarcoma,it is important for clinical physicians and pathologists to raise awareness of this type of tumor.

关键词： Thyroid tumor Papillary thyroid carcinoma Undifferentiated pleomorphic sarcoma BRAF TERT Case report

动脉瘤性蛛网膜下腔出血后脑血管痉挛的影响因素研究

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中国现代药物应用 2024年第2期18卷 7-11页

作者：刘菁芸江小琳程琼汪银洲李永坤武夷山市立医院神经内科 353000 福建医科大学省立临床医学院 350001 福建省立医院神经内科 350001

目的研究动脉瘤性蛛网膜下腔出血(ASAH)后脑血管痉挛(CVS)发生的影响因素。方法66例动脉瘤性蛛网膜下腔出血患者,根据是否发生CVS分为CVS组与无CVS组,每组33例。收集所有患者的社会人口学数据、入院前的症状和身体状况、量表评分、颅脑C... 详细信息

目的研究动脉瘤性蛛网膜下腔出血(ASAH)后脑血管痉挛(CVS)发生的影响因素。方法66例动脉瘤性蛛网膜下腔出血患者,根据是否发生CVS分为CVS组与无CVS组,每组33例。收集所有患者的社会人口学数据、入院前的症状和身体状况、量表评分、颅脑CT表现、临床处理情况、动脉瘤特征及相关实验室检查等资料,通过多因素Logistic回归分析动脉瘤性蛛网膜下腔出血后出现CVS的影响因素。结果共有66例患者符合入组标准,并且均完成了这项研究,大多数患者年龄分布在40~60岁之间,两组患者中均为女性患者较多。两组患者在年龄、性别、吸烟史、咖啡因使用史、动脉瘤情况(大小、定位、高度、直径)、格拉斯哥昏迷量表(GCS)评分、Hunt-Hess分级量表(HHS)分级、Fischer分级量表(FS)分级、白蛋白最低值、C反应蛋白(CRP)最大记录、是否腰椎穿刺和(或)脑室腹腔分流术、是否血管内手术后机械通气方面比较差异无统计学意义(P>0.05);两组患者在视乳头水肿视力减退、脑室内出血、脑积水、动脉瘤宽度、改良Rankin量表(mRS)评分、尿素最大记录、白细胞计数(WBC)最大记录、国际标准化比值(INR)最大记录、血小板计数(PLT)最低值方面比较差异具有统计学意义(P0.05)。结论动脉瘤性蛛网膜下腔出血患者产生颅内炎症状态的强度可能与CVS的发生及其不良后果直接相关。

关键词：动脉瘤性蛛网膜下腔出血脑血管痉挛影响因素 Logistic回归分析

Millisecond-timescale electrodeposition of platinum atom-doped molybdenum oxide as an efficient electrocatalyst for hydrogen evolution reaction

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Frontiers of Materials Science 2022年第3期16卷 171-180页

作者： Yi XIAO Wenxue SHANG Jiyuan FENG Airu YU Lu CHEN Liqiu ZHANG Hongxia SHEN qiong cheng Lichun LIU Song BAI College of Chemistry and Life Sciences Zhejiang Normal UniversityJinhua 321000China College of Biological Chemical Sciences and Engineering&Nanotechnology Research InstituteJiaxing UniversityJiaxing 314000China College of Petroleum Engineering Liaoning Petrochemical UniversityFushun 113000China Collegeof Chemistry Jilin Normal UniversityChangchun 130103China

We present a straightforward method for one-pot electrodeposition of platinum atoms-doped molybdenum oxide(Pt·MoO_(3-x))films and show their superior electrocatalytic activity in the hydrogen evolution reaction(HER).A~15-nm-thick Pt·MoO_(3-x) film was prepared by one-pot electrodeposition at-0.8 V for 1 *** to considerably different solute concentrations,the content of Pt atoms in the electrode-posited composite electrocatalyst is *** Pt crystals or islands were observed on the flat Pt-MoO_(3-x) films,indicating that Pt atoms were homogeneously dispersed within the MoO_(3-x) thin *** catalytic performance and physicochemical features of Pt·MoO_(3-x) as a HER electrocatalyst were *** results showed that our Pt·MoO_(3-x) film exhibits 23-and 11-times higher current density than Pt and MoO_(3-x) electrodeposited individually under the same conditions,*** was found that the dramatic enhancement in the HER performance was principally due to the abundant oxygen *** use of the developed one-pot electrodeposition and doping method can potentially be extended to various catalytically active metal oxides or hydroxides for enhanced performance in various energy storage and conversion applications.

关键词： platinum molybdenum oxide electrodeposition hydrogen evolution reaction doping electrocatalyst

Plant-based meat substitutes by high-moisture extrusion:Visualizing the whole process in data systematically from raw material to the products

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Journal of Integrative Agriculture 2022年第8期21卷 2435-2444页

作者： ZHANG Jin-chuang MENG Zhen cheng qiong-ling LI Qi-zhai ZHANG Yu-jie LIU Li SHI Ai-min WANG Qiang Institute of Food Science and Technology Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-Products ProcessingMinistry of Agriculture and Rural AffairsBeijing 100193P.R.China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190P.R.China

High-moisture extrusion technology should be considered one of the best choices for producing plant-based meat substitutes with the rich fibrous structure offered by real animal meat ***,the extrusion process has been seen as a“black box”with limited information about what occurs inside,causing serious obstacles in developing meat *** study designed a high-moisture extrusion process and developed 10 new plant-based meat substitutes comparable to the fibrous structure of real animal *** study used the Feature-Augmented Principal Component Analysis(FA-PCA)method to visualize and understand the whole extrusion process in three ways systematically and *** established six sets of mathematical models of the high-moisture extrusion process based on 8000 pieces of data,including five types of *** FA-PCA method improved the R^(2) values significantly compared with the PCA *** Way 3 was the best to predict product quality(Z),demonstrating that the gradually molecular conformational changes(Y^(n'))were critical in controlling the final quality of the plant-based meat ***,the first visualization platform software for the high-moisture extrusion process has been established to clearly show the“black box”by combining the virtual simulation *** the software,some practice work such as equipment installation,parameter adjustment,equipment disassembly,and data prediction can be easily achieved.

关键词： plant-based meat substitutes high-moisture extrusion process extrusion parameters models visualization platform software

Advances of machine learning in materials science: Ideas and techniques

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Frontiers of physics 2024年第1期19卷 155-194页

作者： Sue Sin Chong Yi Sheng Ng Hui-qiong Wang Jin-cheng Zheng Department of New Energy Science and Engineering Xiamen University MalaysiaSepang 43900Malaysia Engineering Research Center of Micro-nano Optoelectronic Materials and Devices Ministry of EducationFujian Key Laboratory of Semiconductor Materials and ApplicationsCI Center for OSEDand Department of PhysicsXiamen UniversityXiamen 361005China

In this big data era, the use of large dataset in conjunction with machine learning (ML) has been increasingly popular in both industry and academia. In recent times, the field of materials science is also undergoing a big data revolution, with large database and repositories appearing everywhere. Traditionally, materials science is a trial-and-error field, in both the computational and experimental departments. With the advent of machine learning-based techniques, there has been a paradigm shift: materials can now be screened quickly using ML models and even generated based on materials with similar properties;ML has also quietly infiltrated many sub-disciplinary under materials science. However, ML remains relatively new to the field and is expanding its wing quickly. There are a plethora of readily-available big data architectures and abundance of ML models and software;The call to integrate all these elements in a comprehensive research procedure is becoming an important direction of material science research. In this review, we attempt to provide an introduction and reference of ML to materials scientists, covering as much as possible the commonly used methods and applications, and discussing the future possibilities.

关键词： machine learning materials science

Integration of urchin-like MnCo_(2)O_(4)@C core–shell nanowire arrays within porous copper current collector for superior performance Li-ion battery anodes

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Rare Metals 2024年第2期43卷 599-611页

作者： Xue-Ru Zhang qiong Wu Yong Zhang Xi-Fei Li Ting Xie Yu-cheng Wu Instrumental Analysis Center Hefei University of TechnologyHefei230009China Key Laboratory of Advanced Functional Materials and Devices of Anhui Province Hefei230009China School of Materials Science and Engineering Hefei University of TechnologyHefei230009China Institute of Advanced Electrochemical Energy Xi’an University of TechnologyXi’an710048China

Spinel MnCo_(2)O_(4) is a promising energy storage candidate as anode materials in lithium-ion batteries owing to synergistic effects of two intrinsic solid-state redox ***,low conductivity,poor rate capacity and rapid capacity fading have seriously impaired its practical *** overcome the inferiorities,urchin-like MnCo_(2)O_(4)@C core–shell nanowire arrays have been fabricated directly within a porous copper current collector via a facile hydrothermal method followed by a chemical vapor deposition carbonization *** a typical nanowire,the core is composed of interconnected MnCo_(2)O_(4)nanoparticles and the shell shows as a thin amorphous carbon *** integrated MnCo_(2)O_(4)@C/Cu structure could act as working anodes without using additives or polymer *** MnCo_(2)O_(4)@C/Cu possesses slightly longer Li-ion insertion/desertion pathway than that of MnCo_(2)O_(4)/Cu,the carbon shell could effectively prevent the pulverization of MnCo_(2)O_(4) and lower down charge transfer resistance and actively participate in Li-ion *** rearrangement of carbon atoms during lithiation/delithiation cycling could inhibit the formation of passive solid electrolyte interphase *** a result,the MnCo_(2)O_(4)@C/Cu electrode presents superior rate capacity(600 mAh·g^(−1) at 1 A·g^(−1)) and better stability(797 mAh·g^(−1) after 200 cycles at 100 mA·g^(−1)).The excellent reversible Li ion storage capacity,cycling stability and rate capacity endow MnCo_(2)O_(4)@C/Cu great potential as stable and high output integrated anode materials in Li-ion batteries.

关键词： MnCo_(2)O_(4)@C Urchin-like nanowire arrays Core-shell Integrated anode materials Lithium-ion batteries