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Effect of electrolyte concentration o n the tribological performance of MAO coatings on aluminum alloys

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Frontiers of Chemical Science and Engineering 2020年第6期14卷 1065-1071页

作者： Chao Wang Jun Chen Jihua He Jing Jiang Qinyong Zhang Clean Energy Materials and Engineering Center State Key Laboratory of Electronic Thin Film and Integrated DeviceSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611731China School of Materials Science and Engineering Xihua UniversityChengdu 610039China

Micro-arc oxidation(MAO)is an efficient approach to improve the hardness,wea r resistance,and other properties of aluminum alloys.In order to investigate the effect of the electrolyte concentration on the properties of MAO coatings for LY12 alloy,the voltage variation during the MAO process was recorded.The surface morphologies and phase compositions of the coatings produced with different electrolytes were investigated using scanning electron microscopy and X-ray diffraction,respectively.The roughness and thickness of the coatings were measured using a pocket roughness meter a nd an eddy-current thickness meter,respectively.The tribological performances of the coatings wer e investigated against GCr15 bearing steel on aball-on-disc wear tester in open air.The results showed that with an increase in the Na2SiO3 content,the working voltage of the MAO process decreased,the roughness a nd thickness of the coatings increased significantly,a nd the relative content of the α-Al2O3 phase decreased.With an increase in the KOH content,the working voltage decreased slightly,the roughness and thickness of the coatings increased slightly,and the α-and γ-Al2O3 phase contents remained unchanged.The friction coefficient and wear rate of the coatings increased with an increase in the Na2Sio3 and KoH concentrations.A decrease in the porosity and roughness and an increase in the α-Al2O3 content of the coatings reduced their wear mass loss.

关键词： aluminum alloy micro-arc oxidation coating electrolyte concentration tribological performance

Ginsenoside Rg1 and astaxanthin act on the hypothalamus to protect female mice against reproductive aging

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Chinese Medical Journal 2022年第1期135卷 107-109页

作者： Xiaoman Dai Guirong Zeng Luyan Hong qinyong Ye Xiaochun Chen Jing zhang Department of Neurology and Geriatrics Fujian Institute of GeriatricsFujian Medical University Union HospitalFuzhouFujian 350001China Fujian Key Laboratory of Molecular Neurology Institute of NeuroscienceFujian Medical UniversityFuzhouFujian 350005China

To the Editor:Female infertility due to reproductive aging has become a prominent concern in the population.Evidence indicates that oxidative stress is one of the dominant mechanisms underlying reproductive aging.[1,2]Although female reproductive aging involves gradual changes to the hypothalamic-pituitary-ovarian(HPO)axis,previous studies support a key involvement of the hypothalamus.[3,4]In our recent dataset,it was shown that estrogen-induced oxidative stress led to the senescence of hypothalamic astrocytes that predated reproductive dysfunction.[3]Growing evidence has demonstrated that antioxidants might delay reproductive aging by reducing oxidative damage to ovaries.[1,2]However,the effect of antioxidants on the hypothalamus has not been reported.Astaxanthin(AST),3,3'-dihydroxy-β-carotene-4,4'-dione,is a xanthophyll carotenoid found predominantly in marine animals such as salmon,trout,lobster,and shrimp.Ginseng is a tonic drug in traditional Chinese medicine.Ginsenoside Rg1,a class of steroidal glycosides,is a prominent active anti-aging ingredient within ginseng responsible for these effects.Notably,the two antioxidants freely cross the blood-brain barrier.In this study,we evaluated the effects of these two natural compounds on the hypothalamus and ovaries in protecting female mice from reproductive aging.

关键词： hypothalamus female involvement

Targeting macrophagic 17β-HSD7 by fenretinide for the treatment of nonalcoholic fatty liver disease

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Acta Pharmaceutica Sinica B 2023年第1期13卷 142-156页

作者： Xiaoyu Dong Yiting Feng Dongqin Xu Mengya zhang Xiao Wen Wenhao Zhao Qintong Hu Qinyong Zhang Hui Fu Jie Ping Department of Pharmacology School of Basic Medical SciencesWuhan UniversityWuhan 430071China Department of Anatomy School of Basic Medical SciencesWuhan UniversityWuhan 430071China

Nonalcoholic fatty liver disease(NAFLD)is the most common chronic liver disease worldwide and macrophage polarization plays an important role in its pathogenesis.However,which molecule regulates macrophage polarization in NAFLD remains unclear.Herein,we showed NAFLD mice exhibited increased 17β-hydroxysteroid dehydrogenase type 7(17β-HSD7)expression in hepatic macrophages concomitantly with elevated M1 polarization.Single-cell RNA sequencing on hepatic non-parenchymal cells isolated from wild-type littermates and macrophage-17β-HSD7 knockout mice fed with high fat diet(HFD)for 6 weeks revealed that lipid metabolism pathways were notably changed.Furthermore,17β-HSD7 deficiency in macrophages attenuated HFD-induced hepatic steatosis,insulin resistance and liver injury.Mechanistically,17β-HSD7 triggered NLRP3 inflammasome activation by increasing free cholesterol content,thereby promoting M1 polarization of macrophages and the secretion of pro-inflammatory cytokines.In addition,to help demonstrate that 17β-HSD7 is a potential drug target for NAFLD,fenretinide was screened out from an FDA-approved drug library based on its 17β-HSD7 dehydrogenase inhibitory activity.Fenretinide dose-dependently abrogated macrophage polarization and pro-inflammatory cytokines production,and subsequently inhibited fat deposition in hepatocytes co-cultured with macrophages.In conclusion,our findings suggest that blockade of 17β-HSD7 signaling by fenretinide would be a drug repurposing strategy for NAFLD treatment.

关键词： Nonalcoholic fatty liver disease 17β-HSD7 Macrophage Cholesterol Insulin resistance Fenretinide

High thermoelectric performance at room temperature of n-type Mg_(3)Bi_(2)-based materials by Se doping

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Journal of Magnesium and Alloys 2022年第4期10卷 1024-1032页

作者： Xiaobo Mo Jiansong Liao Guocai Yuan Sha Zhu Xiaobo Lei Lihong Huang Qinyong Zhang Chao Wang Zhifeng Ren Key Laboratory of Fluid and Power Machinery of Ministry of Education School of Materials Science&EngineeringXihua UniversityChengdu 610039China Clean Energy Materials and Engineering Center State Key Laboratory of Electronic Thin Film and Integrated DeviceSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611731China Department of Physics and TcSUH University of HoustonHoustonTX 77204United States

Bi_(2)Te_(3) based alloys have been the most widely used thermoelectric material at low temperature for many decades.Here we report Se doped n-type Mg_(3)Bi_(2) based materials with a thermoelectric figure-of-merit ZT of 0.82 at 300 K and a peak ZT of 1.24 at 498 K,which is comparable to the n-type Bi_(2)Te_(3) and Te doped Mg_(3)Bi_(1.4)Sb_(0.6).The improved thermoelectric performance is benefited from the high carrier concentration and mobility as well as the thermal conductivity reduction.The reduced resistivity increased the power factor at all measured temperatures,leading to a higher engineering ZT(ZTeng)and engineering power factor(PFeng)for n-type Mg_(3)Bi_(2).The n-type Mg_(3)Bi_(1.4)Sb_(0.6) materials are promising for thermoelectric power generation and cooling applications near room temperature.

关键词： Mg_(3)Bi_(2) Zintl compound Thermoelectric Se-doping

Influence of Annealing Temperature on the Microstructure and Electrical Properties of Indium Tin Oxide Thin Films

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Acta Metallurgica Sinica(English Letters) 2014年第2期27卷 368-372页

作者： Yinzhi Chen Hongchuan Jiang Shuwen Jiang Xingzhao Liu Wanli zhang Qinyong Zhang State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of China School of Material Science and Engineering Xihua University

Indium tin oxide （ITO） thin films were prepared on alumina ceramic substrates by radio frequency magnetron sputtering. The samples were subsequently annealed in air at temperatures ranging from 500 to 1,100 ℃ for 1 h. The influences of the annealing temperature on the microstructure and electrical properties of the ITO thin films were investigated, and the results indicate that the as-deposited ITO thin films are amorphous in nature. All samples were crystallized by annealing at 500 ~C. As the annealing temperature increases, the predominant orientation shifts from （222） to （400）. The carrier concentration decreases initially and then increases when the annealing temperature rises beyond 1,000 ℃. The resistivity of the ITO thin films increases smoothly as the annealing temperature increases to just below 900 ℃. Beyond 900 ℃, however, the resistivity of the films increases sharply. The annealing temperature has a significant effect on the stability of the ITO/Pt thin film thermocouples （TFTCs）. TFTCs annealed at 1,000 ℃ show improved high- temperature stability and Seebeck coefficients of up to 77.73 pV/℃.

关键词： Indium tin oxide Thin film Annealing treatment

Electrical property enhancement and lattice thermal conductivity reduction of n-type Mg_(3)Sb_(1.5)Bi_(0.5)-based Zintl compound by In&Se co-doping

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Journal of Materiomics 2023年第3期9卷 431-437页

作者： Tong Liu Jiansong Liao Hang Liu Runyu Wang Guocai Yuan Jing Jiang Yi Niu Xiaobo Lei Lihong Huang Chao Wang Qinyong Zhang Key Laboratory of Fluid and Power Machinery of Ministry of Education School of Materials Science&EngineeringXihua UniversityChengdu610039China Clean Energy Materials and Engineering Center State Key Laboratory of Electronic Thin Film and Integrated DeviceSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu611731China

Mg_(3)Sb_(1.5)Bi_(0.5)-based Zintl compounds have attracted extensive attention as potential thermoelectric materials due to their earth-abundant elements.However,pure and intrinsic Mg_(3)Sb_(1.5)Bi_(0.5)manifests a poor thermoelectric performance because of its low electrical conductivity of about 3×10^(2)S/m at room temperature.In this work,In and Se co-doping was carried out to optimize the thermoelectric perfor-mance of n-type Mg_(3)Sb_(1.5)Bi_(0.5)-based material.The experimental results revealed that the carrier con-centration and mobility of Mg_(3)Sb_(1.5)Bi_(0.5)significantly increased after In and Se co-doping,leading to an improvement of power factor.Simultaneously,lattice thermal conductivity was significantly reduced due to the large mass difference between In and Mg.A maximum zT of 1.64 at 723 K was obtained for the Mg_(3.17)In_(0.03)Sb_(1.5)Bi_(0.49)Se_(0.01)sample.And an average zT value of about 1.1 between 300 and 723 K was achieved,which insures its possible application at medium temperature range as a non-toxic and low-cost TE material.

关键词： Zintl compound Thermoelectric property n-type Mg_(3)Sb_(1.5)Bi_(0.5) In&Se co-doping

Advances in quantitative assessment of parkinsonian motor symptoms with wearable devices

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Science China(Life Sciences) 2018年第12期61卷 1589-1592页

作者： Xiaoli Zhong Jingxue Zheng qinyong Ye Department of Neurology Fujian Institute of GeriatricsFujian Medical University Union HospitalFuzhou 350001China Key Laboratory of Brain Aging and Neurodegenerative Diseases Fujian Key Laboratory of Molecular Neurology Fujian Medical University Fuzhou 350001China

Parkinson's disease(PD)is featured with motor disorder and nonmotor manifestations(Li et al.,2017;zhang et al.2016) under the pathological change of Substantia Nigra(Dong et al.,2017)and non substantia nigra including medial prefrontal cortex(Li et al.,2017).Its primary motor symptoms include tremor(oscillatory movement),bradykinesia(slowness of motion),rigidity(increment of muscle tone),and postural instability,which seriously affect patients'quality of life(Du and Chen,2017).

关键词： Parkinson's disease seriously affect

Sustainable, thermoplastic and hydrophobic coating from natural cellulose and cinnamon to fabricate eco-friendly catering packaging

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Green Energy & Environment 2024年第5期9卷 927-936页

作者： Rumeng Xu Chunchun Yin Jingxuan You Jinming zhang qinyong Mi Jin Wu Jun zhang CAS Key Laboratory of Engineering Plastics Institute of ChemistryChinese Academy of Sciences(CAS)Beijing100190China University of Chinese Academy of Sciences Beijing100049China

Non-degradable polymers cause serious environmental pollution problem,such as the widely-used while unrecyclable coatings which signiﬁcantly affect the overall degradation performance of products.It is imperative and attractive to develop biodegradable functional coatings.Herein,we proposed a novel strategy to successfully prepare biodegradable,thermoplastic and hydrophobic coatings with high transparence and biosafety by weakening the interchain interactions between cellulose chain.The natural cellulose and cinnamic acid were as raw materials.Via reducing the degree of polymerization(DP)of cellulose and regulating the degree of substitution(DS)of cinnamate moiety,the obtained cellulose cinnamate(CC)exhibited not only the thermalﬂow behavior but also good biodegradability,which solves the conﬂict between the thermoplasticity and biodegradability in cellulose-based materials.The glass transition temperature(T_(g))and thermalﬂow temperature(T_(f))of the CC could be adjusted in a range of 150–200℃ and 180–210℃,respectively.The CC with DS<1.2 and DP≤100 degraded more than 60%after an enzyme treatment for 7 days,and degraded more than 80%after a composting treatment for 42 days.Furthermore,CC had no toxicity to human epidermal cells even at a high concentration(0.5 mg mL^(-1)).In addition,CC could be easily fabricated into multifunctional coating with high hydrophobicity,thermal adhesion and high transparence.Therefore,after combining with cellophane and paperboard,CC coating with low DP and DS could be used to prepare fully-biodegradable heat-sealing packaging,art paper,paper cups,paper straws and food packaging boxes.

关键词： Thermoplastic coating Bio-degradable adhesive Natural products Cellulose Eco-friendly packaging

Research on Measurement Method of Ultrasonic Transit Time based on Automatic Gain Control

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Research on Measurement Method of Ultrasonic Transit Time ba...