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Journal of Environmental Sciences 2024年第6期140卷 255-269页

作者： Sheng Zhang Xintian Wang Jiayu Xu qinqin chen Meng Peng Jiming Hao School of Environment Tsinghua UniversityBeijing 100084China School of Environment&Natural Resources Renmin University of ChinaBeijing 100872China State Environmental Protection Key Laboratory of Sources and Control of Air Pollution Complex Beijing 100084China

Recent years have seen a significant increase in interest in green manufacturing as a key driver of global carbon-neutral efforts and sustainable *** find the research hotspots of green manufacturing and reveal future research trends,this study reviewed and analyzed research articles from the Web of Science database on green manufacturing from1991 to 2022 using a bibliometric *** findings indicate a significant rise in the number of articles related to green manufacturing since the ***,there has been an increase in the involvement of scholars from developing countries such as China and India in this *** on the literature review and bibliometric cluster analysis on green manufacturing,we believed that future research may continue following the lines of intelligent technology integration,adoption of frontier engineering techniques,and industry development in line with carbon reduction targets.A framework for future green manufacturing development is proposed,with a focus on Chinese *** framework could provide policy implications for developing countries looking to pursue opportunities for development in green manufacturing.

关键词： Green manufacturing Carbon neutrality Sustainable development Innovative technologies China

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脉冲超声对灰枣片理化及超声液特性的影响

中国食品学报 2024年第7期24卷 297-307页

作者：王凤昭吕明月吕健陈芹芹毕金峰中国农业科学院农产品加工研究所农业农村部农产品加工重点实验室北京100193

为探究脉冲超声持续时间对枣片理化及超声液特性的影响,以灰枣为原料,设置脉冲超声持续时间为15,30,60 s,并分别于1,2,3,4,5 h对灰枣片和超声液进行取样分析。追踪检测灰枣片的色泽、水分状态、质构和微观结构,以及超声液可溶性固形物(T... 详细信息

为探究脉冲超声持续时间对枣片理化及超声液特性的影响,以灰枣为原料,设置脉冲超声持续时间为15,30,60 s,并分别于1,2,3,4,5 h对灰枣片和超声液进行取样分析。追踪检测灰枣片的色泽、水分状态、质构和微观结构,以及超声液可溶性固形物(TSS)、色泽、浊度和电导率的变化。结果表明,随着脉冲超声处理时间的延长,灰枣片中的主要水分由结合水转变为自由水,灰枣片组织吸水膨胀,色泽L*值(42.88~50.71)和△E值(3.69~9.85)呈显著增加的趋势,a*值(由19.88降至14.70)和b*值(由22.39降至19.03)呈显著降低的趋势。脉冲超声处理可诱导灰枣片组织内微通道的形成,随着循环次数的增加和脉冲时间的延长,微通道发生扩张,数量增加,同时伴随咀嚼性、弹性和回复性降低。超声液分析结果表明,高强度脉冲持续时间(30 s和60 s)可使灰枣片与超声液在处理前期(1~2 h)发生快速传质,超声液色泽(△E值:0~26.69)、TSS(0~6.1°Brix)、电导率(0~257.54μs/cm)、浊度(0~8.81 NTU)等显著增加,处理后期(3~5 h),15 s处理组超声液特性呈现出最显著的特性变化;至处理完成,各处理组超声液色泽L*值均达到100,a*值与b*值接近于原始状态;同时30 s和60 s处理组超声液中TSS为0°Brix,传质趋于平衡。结论:可根据灰枣片和超声液特性的改变来判断传质的程度,从而适应不同的加工需求。

关键词：脉冲超声灰枣超声液持续时间可溶性固形物

Multi-objective evolutionary design of selective triple modular redundancy systems against SEUs

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Chinese Journal of Aeronautics 2015年第3期28卷 804-813页

作者： Yao Rui chen qinqin Li Zengwu Sun Yanmei College of Automation and Engineering Nanjing University of Aeronautics and Astronautics

Abstract To improve the reliability of spaceborne electronic systems, a fault-tolerant strategy of selective triple modular redundancy （STMR） based on multi-objective optimization and evolvable hardware （EHW） against single-event upsets （SEUs） for circuits implemented on field pro- grammable gate arrays （FPGAs） based on static random access memory （SRAM） is presented in this paper. Various topologies of circuit with the same functionality are evolved using EHW firstly. Then the SEU-sensitive gates of each circuit are identified using signal probabilities of all the lines in it, and each circuit is hardened against SEUs by selectively applying triple modular redundancy （TMR） to these SEU-sensitive gates. Afterward, each circuit hardened has been evaluated by SEU Simulation, and the multi-objective optimization technology is introduced to optimize the area overhead and the number of functional errors of all the circuits, The proposed fault-tolerant strategy is tested on four circuits from microelectronics center of North Carolina （MCNC） benchmark suite. The experimental results show that it can generate innovative trade-off solutions to compromise between hardware resource consumption and system reliability. The maximum savings in the area overhead of the STMR circuit over the full TMR design is 58% with the same SEU immunity.

关键词： Evolvable hardware Field programmable gatearray Multi-objective approachSelective triple modularredundancy Single event upset

罗森塔尔效应护理结合阶段式康复护理在行颅脑外伤术后患者中的应用

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中西医结合护理（中英文） 2024年第4期10卷 96-98页

作者：李淑梅石丽平陈琴琴复旦大学附属肿瘤医院厦门医院福建厦门361005 厦门医学院附属海沧医院厦门市第六医院福建厦门361000

目的探讨罗森塔尔效应护理模式结合阶段式康复护理在行颅脑外伤术后患者中的效果。方法根据护理方案的不同将2021年1月至2023年1月于厦门医学院附属海沧医院行颅脑外伤术的102例术后患者分为2组,51例对照组患者施以常规护理,51例观察组... 详细信息

目的探讨罗森塔尔效应护理模式结合阶段式康复护理在行颅脑外伤术后患者中的效果。方法根据护理方案的不同将2021年1月至2023年1月于厦门医学院附属海沧医院行颅脑外伤术的102例术后患者分为2组,51例对照组患者施以常规护理,51例观察组患者施以罗森塔尔效应护理模式结合阶段式康复护理。比较2组的创伤后应激反应等指标。结果干预4周及8周后,2组的创伤后应激障碍量表及美国国立卫生研究院卒中量表评分均明显低于术后当日,而心理弹性量表及运动功能量表评分均明显高于术后当日(P均<0.05);组间比较,观察组均更佳(P均<0.05)。组间护理总满意率对比,观察组更好(P<0.05)。结论罗森塔尔效应护理模式结合阶段式康复护理用于行颅脑外伤术的患者术后,可有效减轻创伤应激反应,改善心理弹性水平,保护神经功能,促进肢体功能恢复,且有助于提高护理满意度。

关键词：颅脑外伤手术罗森塔尔效应阶段式康复护理

ANAC087 transcription factor positively regulates age-dependent leaf senescence through modulating the expression of multiple target genes in Arabidopsis

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Journal of Integrative Plant Biology 2023年第4期65卷 967-984页

作者： qinqin chen Jingli Yan Tiantian Tong Peiyu Zhao Shuangshuang Wang Na Zhou Xing Cui Moyu Dai Yuan‐Qing Jiang Bo Yang State Key Laboratory of Crop Stress Biology for Arid Areas College of Life SciencesNorthwest A&F UniversityYangling 712100China College of Plant Protection Henan Agricultural UniversityZhengzhou 450002China

Leaf senescence is the final stage of leaf development and appropriate onset and progression of leaf senescence are critical for reproductive success and *** great progress has been made in identifying key genes regulating leaf senescence and elucidating the underlining mechanisms in the model plant Arabidopsis,there is still a gap to understanding the complex regulatory *** this study,we discovered that Arabidopsis ANAC087 transcription factor(TF)positively modulated leaf *** of ANAC087 was induced in senescing leaves and the encoded protein acted as a transcriptional *** constitutive and inducible overexpression lines of ANAC087 showed earlier senescence than control plants,whereas T-DNA insertion mutation and dominant repression of the ANAC087 delayed senescence rate.A quantitative reverse transcription-polymerase chain reaction(qRT-PCR)profiling showed that the expression of an array of senescence-associated genes was upregulated in inducible ANAC087 overexpression plants including BFN1,NYE1,CEP1,RbohD,SAG13,SAG15,and VPEs,which are involved in programmed cell death(PCD),chlorophyll degradation and reactive oxygen species(ROS)*** addition,electrophoretic mobility shift assay(EMSA)and chromatin immunoprecipitation-quantitative polymerase chain reaction(ChIP-qPCR)assays demonstrated that ANAC087 directly bound to the canonical NAC recognition sequence(NACRS)motif in promoters of its target ***,mutation of two representative target genes,BFN1 or NYE1 alleviated the senescence rate of ANAC087-overexpression plants,suggesting their genetic regulatory *** together,this study indicates that ANAC087serves as an important regulator linking PCD,ROS,and chlorophyll degradation to leaf senescence.

关键词： ANAC087 chlorophyll degradation leaf senescence NAC transcription factor programmed cell death reactive oxygen species

OsPPG encodes a pseudouridine-5'-phosphate glycosidase and regulates rice spikelet development

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The Crop Journal 2024年第3期12卷 698-708页

作者： Rui chen Dagang Tian Yarong Lin Jiaqing Huang qinqin Yang Yupei Li Huaqing Liu Shaohua Yang Jingyang chen Shufen Zhou Feng Wang Shubiao Zhang Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of Education/Key Laboratory of Biological Breeding for Fujian and Taiwan CropsMinistry of Agriculture and Rural AffairsFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Fujian Key Laboratory of Genetic Engineering for Agriculture Biotechnology Research InstituteFujian Academy of Agricultural SciencesFuzhou 350003FujianChina Institute of Resources Environment and Soil FertilizerFujian Academy of Agricultural SciencesFuzhou 350013FujianChina

Florets are the basic structural units of spikelets,and their morphogenesis determines the yield and quality of rice ***,whether and how pseudouridine-5’-phosphate glycosidase participates in rice spikelet development remains an open *** this study,we identified a novel gene,OsPPG,which encodes a peroxisome-localized pseudouridine-5’-phosphate glycosidase and regulates the development of rice *** mutants exhibited abnormal sterile lemma,lemma,palea,lodicule,stamens,and pistils;male sterility;shorter panicles;and reduced plant *** was found to regulate several OsMADS genes,thereby affecting the morphogenesis of rice ***,metabolomics revealed that the OsPPG gene was involved in the decomposition of pseudouridine via the pyrimidine metabolism pathway and may affect the jasmonic acid signaling *** results suggest that OsPPG is a key regulator of rice spikelet development.

关键词： OsPPG Reproductive regulation Spikelet development Rice

Photo-manipulated polyunsaturated fatty acid-doped liposomal hydrogel for flexible photoimmunotherapy

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Chinese Chemical Letters 2024年第4期35卷 268-274页

作者： Xinyue Lan Junguang Liang Churan Wen Xiaolong Quan Huimin Lin qinqin Xu Peixian chen Guangyu Yao Dan Zhou Meng Yu Breast Center Department of General SurgeryNanfang HospitalSouthern Medical UniversityGuangzhou 510515China NMPA Key Laboratory for Research and Evaluation of Drug Metabolism&Guangdong Provincial Key Laboratory of New Drug Screening School of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China Department of Breast Surgery The First People's Hospital of FoshanFoshan 528100China Zhujiang Hospital Southern Medical UniversityGuangzhou 510282China

Despite the synergy of immune checkpoint blockade(ICB) therapy and photodynamic therapy(PDT) holds great promise as countermeasures against breast cancer, exploring long-term or flexible short-time therapeutic strategies in “cold” tumors remains a great challenge. Here, we present a polyunsaturated fatty acid-doped liposomal hydrogel Lp(DHA)@CP Gel loaded with photosensitizer chlorin e6(Ce6) and programmed death-ligand 1 antibody(αPD-L1) for flexible local photoimmunotherapy with merely singledosed administration. The presence of polyunsaturated fatty acid(docosahexaenoic acid, DHA) doped in particle membrane endows liposomes with flexibly reactive oxygen species(ROS)-responsive release capability, which was attributed to the presence of abundant unsaturated groups. The αPD-L1 was repeatedly induced to in situ release in response to the PDT under photo-exposure. The immunogenic cell death(ICD) effect of PDT evoked “cold” breast tumor to “hot” one, and then assisted the cascade releasedαPD-L1 to synergistically boost the immunotherapy. After a single dose of peritumoral administration of Lp(DHA)@CP Gel, the on-demand treatment can maximize patient compliance and safety by adjusting therapeutic behaviors via a photo on-off switch. This work presents a flexible medication platform,showing promise in improving the objective response rate of ICB therapy and minimizing its systemic toxicity.

关键词： Photodynamic therapy Immunotherapy Responsive release Immunogenic cell death Liposomal hydrogel

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公共文化服务与旅游的高质量融合发展

图书馆论坛 2023年第10期43卷 47-54页

作者：陶俊陈秦钦西北大学公共管理学院

文化和旅游公共服务深度融合发展理论与实践研讨会以公共文化服务与旅游深度融合发展为主线,从行业领域、空间地理、线上线下、政策和实践等维度探讨文化和旅游在更广范围、更深层次、更高水平上的融合发展。文章综述会议主要内容,聚焦... 详细信息

文化和旅游公共服务深度融合发展理论与实践研讨会以公共文化服务与旅游深度融合发展为主线,从行业领域、空间地理、线上线下、政策和实践等维度探讨文化和旅游在更广范围、更深层次、更高水平上的融合发展。文章综述会议主要内容,聚焦文旅深度融合、公共文化服务高质量发展、旅游公共服务、文旅数字化等热点话题,梳理新理念、新观点和新实践。

关键词：文旅融合公共文化服务高质量发展旅游业

维普期刊数据库博看期刊

学术创业成长进化的知识积累机制——基于比较纵向案例的发现

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科学学与科学技术管理 2022年第4期43卷 57-74页

作者：陈芹芹张胜西安交通大学公共政策与管理学院

学术创业已成为当今研究型大学发展的新潮流，但针对学术创业的成长进化问题，现有文献并未清晰地指出走向成功的创业进化路径。基于知识视角，对比工业制造、软件服务和工程建造3个领域的学术创业案例，结论发现：学术创业聚焦创建“... 详细信息

学术创业已成为当今研究型大学发展的新潮流，但针对学术创业的成长进化问题，现有文献并未清晰地指出走向成功的创业进化路径。基于知识视角，对比工业制造、软件服务和工程建造3个领域的学术创业案例，结论发现：学术创业聚焦创建“熊彼特租金”，遵循自主学习积累“用户知识—工厂知识—资本知识”的进化顺序，能够有效跨越创业陷阱、实现创业进化。

关键词：学术创业熊彼特租金创业陷阱创业知识

硅胶导尿管在扩张法耳再造术后持续负压吸引中的应用

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中国美容医学 2024年第1期33卷 37-40页

作者：冉力李娅萍王凡陈勤勤陆军军医大学第一附属医院整形外科重庆400038

目的:探讨一种由硅胶导尿管、一次性吸引管及20 ml一次性注射器制作的负压引流装置在扩张法耳再造术后的临床应用效果。方法:收集2021年1月-2022年1月笔者医院整形外科收治的扩张法耳再造患者19例,采用该装置进行术后引流,观察其引流效... 详细信息

目的:探讨一种由硅胶导尿管、一次性吸引管及20 ml一次性注射器制作的负压引流装置在扩张法耳再造术后的临床应用效果。方法:收集2021年1月-2022年1月笔者医院整形外科收治的扩张法耳再造患者19例,采用该装置进行术后引流,观察其引流效果,负压调整次数,吸闭次数,术后并发症情况,耳廓与亚结构的显现情况。结果:临床小实验结果显示,两次抽吸引流管内空气后,普通一次性引流管变软,略有变形;输液器引流管完全吸闭;硅胶导尿管无变形吸闭现象。硅胶导尿管作为引流管引流通畅,皮瓣血运良好,耳廓形态满意无一例出现吸闭、感染现象,术区伤口均为一期愈合,平均日引流量为8~17 ml,拔管时间为4~7 d。结论:该装置既能使皮瓣与耳支架紧密贴合,保证再造耳满意形态,又能充分引流,实现零吸闭,其抗菌抗感染的材质及双腔结构还能减少感染概率并且提供预防性使用抗生素冲洗的机会。

关键词：硅胶导尿管耳再造术引流临床小实验零吸闭扩张法