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Identification and functional characterization of female antennae-biased odorant receptor 23 involved in acetophenone detection of the Indian meal moth Plodia interpunctella

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Insect Science 2024年第1期31卷 59-78页

作者： Qi Chen Xiaoyan Zhu Guoqing Kang Qiling Yu qingxin liu Lin Du Yi Yang Xinyu He Ying Zhao Junjie Zhang Ying Hu Bingzhong Ren Jilin Provincial Key Laboratory of Animal Resource Conservation and Utilization School of Life SciencesNortheast Normal UniversityChangchunChina Key Laboratory of Vegetation Ecology Ministry of EducationNortheast Normal UniversityChangchunChina Jilin Provincial Engineering Laboratory of Avian Ecology and Conservation Genetics Northeast Normal UniversityChangchunChina Engineering Research Center of Natural Enemies Institute of Biological ControlJilin Agricultural UniversityChangchunChina

The Indian meal moth,Plodia interpunctella(Lepidoptera:Pyralidae),a globally distributed storage pest,relies on odors that are emitted from stored foods to select a suitable substrate for ***,the molecular mechanism underlying the chemical communication between *** and its host remains *** this study,130 chemosensory genes were identified from the transcriptomes of 7 *** tissues,and the quantitative expression levels of all 56 *** odorant receptor genes(PintORs)were validated using real-time quantitative polymerase chain *** functional characteristics of 5 PintORs with female antennae-biased expression were investigated using 2-electrode voltage clamp recordings in Xenopus laevis ***23 was found to be specifically tuned to *** could elicit a significant electrophysiological response and only attracted mated females when compared with males and virgin *** addition,molecular docking predicted that the hydrogen bonding sites,TRP-335 and ALA-167,might play key roles in the binding of PintOR23 to *** study provides valuable insights into the olfactory mechanism of oviposition substrate detection and localization in *** and points toward the possibility of developing eco-friendly odorant agents to control pests of stored products.

关键词： acetophenone docking EAG odorant receptor Plodia interpunctella TEVC

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Coexistence of Dirac and Weyl points in non-centrosymmetric semimetal NbIrTe_(4)

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Chinese Physics B 2024年第4期33卷 146-151页

作者：刘清馨付阳丁鹏飞马欢郭朋杰雷和畅王善才 Department of Physics Key Laboratory of Quantum State Construction and ManipulationRenmin University of ChinaBeijing 100872China Beijing Key Laboratory of Opto-Electronic Functional Materials&Micro-Nano Devices Renmin University of ChinaBeijing 100872China

Using angle-resolved photoemission spectroscopy and density functional theory calculations methods,we investigate the electronic structures and topological properties of ternary tellurides NbIrTe_(4),a candidate for type-II Weyl *** demonstrate the presence of several Fermi arcs connecting their corresponding Weyl points on both termination surfaces of the topological *** analysis reveals the existence of Dirac points,in addition to Weyl points,giving both theoretical and experimental evidences of the coexistence of Dirac and Weyl points in a single *** findings not only confirm NbIrTe_(4) as a unique topological semimetal but also open avenues for exploring novel electronic devices based on its coexisting Dirac and Weyl fermions.

关键词： Fermi arc Weyl point Dirac point angle-resolved photoemission spectroscopy

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改进?鱼优化算法和熵测度的图像多阈值分割

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智能系统学报 2024年第2期19卷 381-391页

作者：刘庆鑫李霓贾鹤鸣齐琦海南大学计算机科学与技术学院海南海口570228 海南师范大学数学与统计学院海南海口571158 海南师范大学数据科学与智慧教育教育部重点实验室海南海口571158 三明学院信息工程学院福建三明365004

针对传统图像多阈值分割方法存在效率低、分割质量差等问题,提出一种改进?鱼优化算法并结合熵测度(weight lens remora optimization algorithm,WLROA)的图像多阈值分割方法。针对?鱼优化算法易陷入局部极值等缺陷,引入透镜成像反向学... 详细信息

针对传统图像多阈值分割方法存在效率低、分割质量差等问题,提出一种改进?鱼优化算法并结合熵测度(weight lens remora optimization algorithm,WLROA)的图像多阈值分割方法。针对?鱼优化算法易陷入局部极值等缺陷,引入透镜成像反向学习策略,生成透镜反向解来增加种群多样性,进而提高算法跳出局部极值能力;提出一种自适应权重因子,对个体位置进行自适应扰动,提高算法探索能力。以最小化交叉熵作为优化目标,利用WLROA确定最小交叉熵并获得相应分割阈值。选取部分伯克利大学分割数据集图像和遥感图像测试提出算法的分割性能,测试结果表明,WLROA与其他知名算法相比具有更好的分割效果,能够有效实现复杂图像的精确处理。

关键词：图像处理多阈值分割 ?鱼优化算法最小交叉熵透镜成像反向学习自适应权重因子全局优化遥感图像

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口腔种植牙修复在牙列缺损患者中的应用效果分析

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中国社区医师 2024年第18期40卷 35-37页

作者：刘庆新临沂市莒南县中医医院口腔科山东临沂276600

目的:分析口腔种植牙修复在牙列缺损患者中的应用效果。方法:选取2020年8月—2022年3月临沂市莒南县中医医院收治的牙列缺损患者136例作为研究对象,以随机数字表法分为对照组与研究组,各68例。对照组采用常规修复治疗,研究组采用口腔种... 详细信息

目的:分析口腔种植牙修复在牙列缺损患者中的应用效果。方法:选取2020年8月—2022年3月临沂市莒南县中医医院收治的牙列缺损患者136例作为研究对象,以随机数字表法分为对照组与研究组,各68例。对照组采用常规修复治疗,研究组采用口腔种植牙修复治疗。比较两组临床疗效、牙周指标及口腔功能。结果:研究组治疗总有效率高于对照组,差异有统计学意义(P=0.003)。治疗后,两组牙龈指数、菌斑指数、龈沟出血指数评分低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组咀嚼功能、语言功能、固位功能、牙体美观度评分高于治疗前,且研究组高于对照组,差异有统计学意义(P<0.05)。结论:口腔种植牙修复在牙列缺损患者中的应用效果显著,可改善患者牙周指标及口腔功能,值得临床应用。

关键词：口腔种植牙修复牙列缺损牙周指标口腔功能

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融合非线性收敛因子与变异准反射学习的哈里斯鹰优化算法

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智能系统学报 2024年第3期19卷 738-748页

作者：宋美佳贾鹤鸣林志兴刘庆鑫三明学院网络中心福建三明365004 三明学院信息工程学院福建三明365004 海南大学计算机科学与技术学院海南海口570228

针对哈里斯鹰优化算法(Harris Hawks optimization,HHO)易早熟收敛、寻优精度低、收敛速度慢等问题,提出一种融合非线性收敛因子与变异准反射学习的哈里斯鹰优化算法(improved Harris Hawks optimization,IHHO)。首先,初始化阶段引入Cir... 详细信息

针对哈里斯鹰优化算法(Harris Hawks optimization,HHO)易早熟收敛、寻优精度低、收敛速度慢等问题,提出一种融合非线性收敛因子与变异准反射学习的哈里斯鹰优化算法(improved Harris Hawks optimization,IHHO)。首先,初始化阶段引入Circle混沌映射,提高初始化种群多样性和种群位置质量;其次,引入Sigmoid非线性收敛因子,平衡全局探索和局部开发能力;最后,针对HHO算法易陷入局部最优问题,提出变异准反射学习(quasi-reflection-based learning,QRBL)策略,提高种群活力,进一步提高算法局部收敛能力。仿真实验采用13个标准测试函数和1个经典工程问题对改进算法进行测试,结果表明改进算法收敛精度、收敛速度均有较大提高,适用于解决实际问题。

关键词：哈里斯鹰优化算法非线性收敛因子准反射学习准反向学习混沌映射工程问题元启发算法群智能

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针对动脉粥样硬化性心脑血管疾病的新型降脂药物的作用机制及研究进展

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中国医学创新 2024年第5期21卷 157-164页

作者：刘惠蒋萌束宁德刘庆新滨州医学院附属医院神经内科山东滨州256603 滨州医学院山东烟台264003

动脉粥样硬化性疾病是心脑血管疾病的主要病因之一,动脉斑块的形成导致血管狭窄,循环系统血流障碍,从而导致组织缺氧而引发一系列心脑血管疾病,严重狭窄或斑块破裂形成血栓可导致循环血管闭塞,从而导致组织坏死,增加心脑血管疾病致死风... 详细信息

动脉粥样硬化性疾病是心脑血管疾病的主要病因之一,动脉斑块的形成导致血管狭窄,循环系统血流障碍,从而导致组织缺氧而引发一系列心脑血管疾病,严重狭窄或斑块破裂形成血栓可导致循环血管闭塞,从而导致组织坏死,增加心脑血管疾病致死风险。目前动脉粥样硬化的治疗手段主要是针对循环中血脂水平的降低,他汀类药物仍然是一线降脂药物,尽管他汀类药物已经被证实具有良好的疗效和广泛适用性,但由于其剂量依赖性和副作用,相当一部分患者在血脂水平未达到指南推荐的标准时就不得不停用,因此,开发除他汀类药物之外能够降低血脂水平并具有良好疗效和耐受性的替代治疗药物具有重要意义。本篇文章主要综述目前针对动脉粥样硬化性心脑血管疾病的降脂新型药物的作用机制及临床研究进展,以期为动脉粥样硬化降脂治疗提供新的诊疗思路。

关键词：心脑血管疾病动脉粥样硬化降脂治疗降脂药物

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Implication of platelet-derived growth factor receptor alpha in prostate cancer skeletal metastasis

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Chinese Journal of Cancer 2011年第9期30卷 612-619页

作者： qingxin liu Danielle Jernigan Yun Zhang Alessandro Fatatis Department of Pharmacology and Physiology Drexel University College of Medicine Philadelphia PA 19102 USA. Department of Pathology and Laboratory Medicine Drexel University College of Medicine Philadelphia PA 19102 USA.

Metastasis represents by far the most feared complication of prostate carcinoma and is the main cause of death for *** skeleton is frequently targeted by disseminated cancer cells and represents the sole site of spread in more than 80% of prostate cancer *** between select malignant phenotypes and the microenvironment of colonized tissues is broadly recognized as the culprit for the organ-tropism of cancer ***,we review our recent studies showing that the expression of platelet-derived growth factor receptor alpha(PDGFR a) supports the survival and growth of prostate cancer cells in the skeleton and that the soluble fraction of bone marrow activates PDGFR a in a ligand-independent ***,we offer pre-clinical evidence that this receptor is a viable target for therapy.

关键词：前列腺癌细胞生长因子受体血小板衍生并发症兼容性微环境殖民化

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Electrochromic effect in domain-inversion process in LiNbO_(3):Ru:Fe crystals

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Chinese Science Bulletin 2005年第24期50卷 2799-2803页

作者： XI qingxin liu De'an ZHI Ya'nan ZHU Luan liu Liren Shanghai Institute of Optics and Fine Mechanics Chinese Academy ofSciences Shanghai 201800 China

A reversible electrochromic effect accompany- ing domain-inversion during the electrical poling process in LiNbO3: Ru: Fe crystals at room temperature has been ob- served. In electrode area, both electrochromism and do- main-inversion occur alternately, and electrochromism is also reversible during back-switch poling, which is experi- mentally verified and whose mechanism is briefly explained using a microstructure ferroelectric model. In addition, be- cause of the enhancing elcctrochromic effect, different from the undoped LiNbO3 crystals, the coercive filed (21.0 kV/mm or so) measured in LiNbO3: Ru: Fe is lower than its break- down field, thus providing a possible new technique for real- izing the domain-inversion by constant electric field rather than a pulsed one.

关键词：铌酸锂晶体钌铁掺杂电致变色磁畴逆变

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Micron-to nano-pore characteristics in the shale of Longmaxi Formation,southeast Sichuan Basin

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Petroleum Research 2017年第2期2卷 156-168页

作者： Wenming Ji Yan Song Zhenxue Jiang Mianmo Meng qingxin liu Fenglin Gao State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China Unconventional Natural Gas Research Institute of China University of Petroleum Beijing102249China School of Geosciences China University of PetroleumShandong266580China PetroChina Research Institute of Petroleum Exploration and Development Beijing100083China

For shale of Lower Silurian Longmaxi Formation in Chongqing,southeast Sichuan Basin,characteristics of micro-nano pores in marine shale reservoirs were well studies by means of Field-Emission Scanning Electron Microscope and Low-temperature Low-pressure Adsorption Experiment of CO_(2)and N_(2).Results showed that six types of pore were developed in the shale of Longmaxi Formation,i.e.,organic pores,intergranular pores,intragranular pores,intercrystalline pores,dissolution pores and microfractures,among which the organic pores and intragranular pores in interlayers of clay minerals were most developed,and a plenty of dissolution pores were also well developed because of high thermal evolution *** specific surface area of the shale in Longmaxi Formation ranged from 3.5 to 18.1 m^(2)/g,BJH total pore volume was from 0.00234 to 0.01338 cm^(3)/g,DA specific surface area of micropores vaired from 1.3 to 7.3 m^(2)/g,and DA pore volume ranged from 0.00052 to 0.00273 cm^(3)/*** specific surface area of micropores in the shale accounted for 23.1%-80.2%of total specific surface area with an average of 50.3%,and the pore volume of micropores accounted for 12.1%-48.5%of total pore volume with an average of 32.3%.Micropore was the main storage space in shale reservoir for methane adsorption,that because capacities of specific surface area provided by micropores were considerably greater than those provided by mesopores and *** size distribution of the shale was complex,and multiple different peaks occurred in the pore size curves,showing two or three peaks in the range from 0 to 100 nm and four peaks *** had a good linear relationship with pore structure parameters of micropores,mesopores t macropores and total pores in the shale,indicating that TOC was the most important control factor for micron-to nano-pore structure in the *** normalization of pore structure parameters to TOC,the pore structure parameters of total pores and mesopores

关键词： Marine shale Micron-to nano-pore Specific surface area Pore volume Pore structure parameter Longmaxi Formation Sichuan Basin

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New Argon Stopper Technology for Slab Casting

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China's Refractories 2021年第2期30卷 41-44页

作者： Gerald NITZL Xiaohui liu qingxin liu Jie SHEN Yong TANG RHI Magnesita Wien 1120Austria RHI Magnesita Dalian 116600China RHI Magnesita Shanghai 200021China RHI Magnesita Leoben 8700Austria

Argon addition into the casting channel reduces the amount of clogging on the refractory wall to allow long sequence casting of aluminium-killed steel *** key to minimum surface defects on the final product is to establish the optimum quantity by optimising the gas distribution below the stopper *** is achieved by new argon stopper technology which supports low gas quantities with homogeneous gas and bubble distributions to float non-metallic inclusions(NMI)in the continuous casting mould.

关键词： argon stopper technology slab casting aluminium-killed steel non-metallic inclusions

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