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Morphological Evolution of Self-Assembled Sodium Dodecyl Sulfate/Dodecyltrimethylammonium Bromide@Epoxy-β-Cyclodextrin Supramolecular Aggregates Induced by Temperature

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Journal of Renewable Materials 2024年第4期12卷 629-641页

作者： qingran Meng Wenwen Xu Zuobing Xiao Qinfei Ke Xingran Kou Key Laboratory of Textile Science&Technology Ministry of EducationCollege of TextilesDonghua UniversityShanghai201620China Collaborative Innovation Center of Fragrance Flavor and Cosmetics School of Perfume and Aroma Technology(Shanghai Research Institute of Fragrance&Flavour Industry)Shanghai Institute of TechnologyShanghaiChina

Bio-based cyclodextrins(CDs)are a common research object in supramolecular *** special cavity structure of CDs can form supramolecular self-assemblies such as vesicles and microcrystals through weak interaction with guest *** different forms of supramolecular self-assemblies can be transformed into each other under certain *** regulation of supramolecular self-assembly is not only helpful to understand the self-assembly principle,but also beneficial to its *** the present study,the self-assembly behavior of epoxy-β-cyclodextrin(EP-β-CD)and mixed anionic and cationic surfactant system(sodium dodecyl sulfate/dodecyltrimethylammonium bromide,SDS/DTAB)in aqueous solution was *** and particle size characterization found that the SDS/DTAB@EP-β-CD complex,as the basic building unit,self-assembled into worm-like micelles at lower temperatures and vesicles at higher *** magnetic resonance(NMR)and Fourier transform infrared spectroscopy(FT-IR)analysis revealed that the driving force for the formation of vesicles and worm-like micelles was the hydrogen bonds between EP-β-CD molecules,while water molecules played an important role in promoting vesicle formation between SDS/DTAB@EP-β-CD ***,the mechanism of the morphologic transformation of SDS/DTAB@EP-β-CD supramolecular aggregates induced by temperature was elucidated by exploring the self-assembly process,which may provide an excellent basis for the development of delivery carriers.

关键词： Epoxy-β-cyclodextrin SDS/DTAB self-assembly temperature morphological evolution

Compact multilayer liquid crystal polymer lowpass filter with 8-shaped inductor

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The Journal of China Universities of Posts and Telecommunications 2024年第3期31卷 80-86页

作者： Liu Weihong Wang Guoxiu Liu qingran School of Electronic Engineering Xi'an University of Posts and TelecommunicationsXi'an 710121China

Lumped element lowpass filter(LPF)for ultra-high frequency(UHF)radio frequency(RF)front-end system is presented based on multilayer liquid crystal polymer(LCP).The lumped element LPF can achieve miniaturization and one transmission zero on the stopband by the 8-shaped *** lumped element LPF is fabricated on a 4-layer LCP substrate with a compact size of 9 mm×14 mm×0.193 *** measured cut off frequency of the lumped element LPF is 0.5 GHz with insertion loss(IL)less than 0.37 *** measured and simulated results suggest that it is a possible candidate for the application of UHF RF front-end system.

关键词： lowpass filter(LPF) multilayer liquid crystal polymer(LCP) miniaturization 8-shaped inductor

智能媒体对青少年性别刻板印象形成的影响研究

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艺术科技 2021年第20期34卷 236-239页

作者：杨清然扬州大学新闻与传媒学院江苏扬州225009

随着智能传播技术的迅猛发展,青少年对社交媒体的使用日益频繁,媒体对他们认识世界、树立“三观”起到了越来越大的作用。从云会议、云课堂到社交媒体内容的智能推送,智能转播技术与青少年的学习和生活密切相关。同时,青少年也正在通过... 详细信息

随着智能传播技术的迅猛发展,青少年对社交媒体的使用日益频繁,媒体对他们认识世界、树立“三观”起到了越来越大的作用。从云会议、云课堂到社交媒体内容的智能推送,智能转播技术与青少年的学习和生活密切相关。同时,青少年也正在通过社交媒体形成对各种事物的刻板印象,其中就包括性别刻板印象。文章研究智能媒体对青少年性别刻板印象形成的影响,分析当代青少年的性别刻板印象状态,同时,提出未来应该如何改变智能传播技术以消除偏见,旨在发挥社交媒体在青少年性别刻板印象形成方面的积极作用。

关键词：智能传播技术智能媒体青少年性别刻板印象

Long-term variation of Arctic Sudden Stratospheric Warmings(SSW) and potential causes

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Earth and Planetary Physics 2024年第5期8卷 742-752页

作者： qingran Li ShaoDong Zhang KaiMing Huang ChunMing Huang Yun Gong WenTao Tang Zheng Ma School of Electronic Information Wuhan University Guizhou Normal University Key Laboratory of Geospace Environment and Geodesy Ministry of Education State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing School of Electronic Information Engineering Jingchu University of Technology

Utilizing the European Centre for Medium-Range Weather Forecast(ECMWF) Reanalysis v5(ERA5), for the first time, we have confirmed close links among Sudden Stratospheric Warmings(SSWs) in the Northern Hemisphere(NH), the polar vortices, and stratospheric Planetary Waves(PWs) by analyzing and comparing their trends. Interestingly, within overall increasing trends, the duration and strength of SSWs exhibit increasing and decreasing trends before and after the winter of 2002, respectively. To reveal possible physical mechanisms driving these trends, we analyzed the long-term trends of the winter(from December to February) polar vortices and of stratospheric PWs with zonal wave number 1. Notably, our results show that in all three time periods(the entire period of 41winters, 1980 to 2020, and the two subperiods — 1980-2002 and 2002-2020) enhancing SSWs were always accompanied by weakening winter polar vortices and strengthening polar PWs like Stationary Planetary Waves(SPWs) and 16-day waves, and vice versa. This is the first proof, based on ERA5 long-term trend data, that weakening polar vortices and enhancing stratospheric PWs(especially SPWs) could cause an increase in SSWs.

关键词： sudden stratospheric warmings stationary planetary waves 16-day waves polar vortrices long-term trend correlation coefficient

Lactate regulates major zygotic genome activation by H3K18 lactylation in mammals

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National Science Review 2024年第2期11卷 124-134页

作者： Jingyu Li Weibo Hou Qi Zhao Wei Han Hongdi Cui Songling Xiao Ling Zhu Jiadan Qu Xiaoyu Liu Weitao Cong Jingling Shen Yuzheng Zhao Shaorong Gao Guoning Huang qingran Kong Chongqing Key Laboratory of Human Embryo Engineering Center for Reproductive Medicine Chongqing Health Center for Women and ChildrenWomen and Children's Hospital of Chongqing Medical University Oujiang Laboratory Zhejiang Provincial Key Laboratory of Medical Genetics Key Laboratory of Laboratory MedicineMinistry of EducationSchool of Laboratory Medicine and Life Sciences Wenzhou Medical University Frontier Science Center for Stem Cell Research School of Life Sciences and Technology Tongji University School of Pharmaceutical Science Wenzhou Medical University Institute of Life Sciences College of Life and Environmental Sciences Wenzhou University Optogenetics&Synthetic Biology Interdisciplinary Research Center State Key Laboratory of Bioreactor Engineering Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism School of Pharmacy East China University of Science and Technology

Lactate is present at a high level in the microenvironment of mammalian preimplantation embryos in vivo and in vitro. However, its role in preimplantation development is unclear. Here, we report that lactate is highly enriched in the nuclei of early embryos when major zygotic genome activation(ZGA) occurs in humans and mice. The inhibition of its production and uptake results in developmental arrest at the 2-cell stage, major ZGA failure, and loss of lactate-derived H3K18lac, which could be rescued by the addition of Lac-Co A and recapitulated by overexpression of H3K18R mutation. By profiling the landscape of H3K18lac during mouse preimplantation development, we show that H3K18lac is enriched on the promoter regions of most major ZGA genes and correlates with their expressions. In humans, H3K18lac is also enriched in ZGA markers and temporally concomitant with their expressions. Taken together, we profile the landscapes of H3K18lac in mouse and human preimplantation embryos, and demonstrate the important role for H3K18lac in major ZGA, showing that a conserved metabolic mechanism underlies preimplantation development of mammalian embryos.

关键词： mammalian preimplantation development lactate epigenetic remodeling histone lactylation zygotic genome activation

“榫卯”连接式全程数字化组合导板在全口种植手术中的临床应用

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中国口腔种植学杂志 2021年第5期26卷 306-312页

作者：李岩杨清然徐光宙国家口腔疾病临床医学研究中心上海市口腔医学重点实验室上海交通大学医学院附属第九人民医院口腔外科 200011

目的本项研究旨在探索榫卯连接式全程数字化组合导板在全口种植外科手术中应用的临床效果。方法本项研究选取一位由于重度牙周炎导致全口上下颌牙槽骨吸收至根尖1/3,全口上下颌牙齿松动III度,要求全口种植修复的患者为研究对象。运用一... 详细信息

目的本项研究旨在探索榫卯连接式全程数字化组合导板在全口种植外科手术中应用的临床效果。方法本项研究选取一位由于重度牙周炎导致全口上下颌牙槽骨吸收至根尖1/3,全口上下颌牙齿松动III度,要求全口种植修复的患者为研究对象。运用一项自主设计研发的榫卯连接式全程数字化组合导板,该导板利用榫卯式的连接,将定位导板、截骨导板、种植导板之间实现互相组合。利用牙支持式定位导板组合截骨导板实现截骨导板的精确定位并固定,截骨导板能够有效地指导骨面修整,实现以修复为导向的全程数字化种植外科。结果通过术后锥形束CT将种植体植入位点与术前设计对比,发现该导板系统精确度较高,总体角度偏差为2.27°,总体种植体尖端偏差值为1.93 mm,种植体颈部偏差值为1.77 mm,病例即刻修复效果较为理想。结论自主设计研发的榫卯连接组合式全程数字化导板,作为一种改良的组合式数字化导板,为真正实现针对无牙颌病例的全程数字化种植外科提供了新的选择,减少了全口无牙颌种植手术的难度和时间,提高了种植位点与角度的精确度,但其临床效果仍然需要未来更大样本量、更长随访期的研究支持。

关键词：全程数字化种植榫卯结构组合式数字化种植外科导板全口修复

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全麻颅内支架成形术后尿管拔除时机的选择

实用临床医药杂志 2017年第8期21卷 76-78页

作者：王宁宁黄捷杨清然河北省沧州市人民医院介入科河北沧州061000 河北省沧州市人民医院护理部河北沧州061000

目的探讨尿管拔出时机对全麻颅内动脉支架成形术后患者的影响。方法选取在本院行全面颅内支架成形术的82例颅内动脉狭窄患者进行研究,将其随机分为对照组与观察组,每组41例。其中观察组患者尿管拔除时机为麻醉Steward苏醒评分达4分后,... 详细信息

目的探讨尿管拔出时机对全麻颅内动脉支架成形术后患者的影响。方法选取在本院行全面颅内支架成形术的82例颅内动脉狭窄患者进行研究,将其随机分为对照组与观察组,每组41例。其中观察组患者尿管拔除时机为麻醉Steward苏醒评分达4分后,对照组为术后24h接受解除术侧肢体制动后拔除尿管。比较2组患者是否出现头痛、血压升高、意识障碍、癫痫发作、脑出血等临床症状,记录并比较2组患者TCD监测结果以及第一次排尿量和排尿方法。结果观察组患者头痛、意识障碍、癫痫发作等临床症状发生率明显低于对照组,其血压>150mm Hg及TCD监测显示同侧大脑中动脉血流速度呈1.5~3倍增加的患者所占比率也显著高于对照组(P<0.05);2组患者第1次排尿量比较无差异,自行排尿成功率和诱导排尿成功率比较均无差异,且自行排尿成功率均较高,2组患者均无导尿情况发生。结论对行全麻颅内支架成形术的患者而言,护理人员术前给予床上排尿指导,麻醉诱导前应用盐酸利多卡因胶浆后留置尿管,可增加患者对留置尿管引发的不良反应的耐受性,同时在术后苏醒早期应用个体化的尿管拔除方法,可有效避免尿潴留和尿管刺激征引起的脑高灌注综合征等并发症的发生,极大地改善了患者的舒适性,而且不会对患者排尿情况产生不良影响。

关键词：全麻颅内支架成形术尿管拔除时机脑过度灌注综合征

高锰酸钾法测定饲料钙含量的水浴陈化条件研究

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饲料工业 2020年第21期41卷 57-60页

作者：鲁琼芬李琦华冷静杨庆然毛华明云南农业大学动物科学技术学院云南省动物营养与饲料重点实验室云南昆明650201 龙陵县畜牧工作站云南保山678300

试验旨在明确应用高锰酸钾法测定饲料钙含量时,定量沉淀草酸钙的水浴陈化条件。试验选取单一饲料原料、配合饲料和浓缩饲料共16个样品,采用2×3交叉试验设计,设定水浴温度(80、85、90℃)及时间(0.5、1、2 h),对草酸钙沉淀水浴完成后将... 详细信息

试验旨在明确应用高锰酸钾法测定饲料钙含量时,定量沉淀草酸钙的水浴陈化条件。试验选取单一饲料原料、配合饲料和浓缩饲料共16个样品,采用2×3交叉试验设计,设定水浴温度(80、85、90℃)及时间(0.5、1、2 h),对草酸钙沉淀水浴完成后将溶液冷却至室温,再做后续测定步骤,每个样品重复测定3次,根据二因素分析结果,再分别与放置过夜陈化的对照组测定值做单因素方差分析,筛选最佳水浴温度和时间。在不同水浴温度和时间条件下,除磷酸氢钙和石粉外的其他样品钙含量测定值存在显著差异(P0.05);当饲料钙含量大于22%时,水浴时间和温度对饲料中钙含量的测定影响差异不显著(P>0.05)。由此可见,水浴温度和时间会影响饲料钙含量的测定值,可用85℃水浴2 h或90℃水浴1~2 h替代放置过夜陈化。

关键词：饲料钙含量高锰酸钾法过夜陈化水浴温度水浴时间

科普讲座制作中存在的问题及对策建议——以“小球大世界”为例

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今日科苑 2022年第7期 83-90页

作者：赵东平吴倩雯杨清然北京科学中心北京100032

专家讲座是科普场馆传统的宣教方式,在科学传播中发挥着重要的作用。有必要深入调查观众的参与意愿以及讲座开展情况,以改进讲座形式,扩大观众面。在观众特点分析方面,本文通过问卷调查对观众区县占比、家长学历构成、观众年龄构成等方... 详细信息

专家讲座是科普场馆传统的宣教方式,在科学传播中发挥着重要的作用。有必要深入调查观众的参与意愿以及讲座开展情况,以改进讲座形式,扩大观众面。在观众特点分析方面,本文通过问卷调查对观众区县占比、家长学历构成、观众年龄构成等方面进行分析,结果表明城六区参与观众多、远郊区观众少,家长本科以上学历占比较大,青少年则以4~6年级为主;在线下讲座转化为线上讲座方面,项目组咨询专业人士意见,主要存在线下线上观众不一致、互动形式单一、科学语言概括化等问题。本文结合观众特点,针对线上讲座存在问题提供对策建议,以期为其它讲座提供借鉴。

关键词：专家讲座主题设计视频制作