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核电厂定位销局部干法水下TIG焊接工艺

焊接学报 2024年第2期45卷 7-12,I0003页

作者：孙清洁张清华赵永庆郭佳威李天佑班华康侯少军哈尔滨工业大学先进焊接与连接国家重点实验室哈尔滨150001 哈尔滨工业大学(威海) 特种焊接技术省重点实验室威海264209

以核电厂定位销水下焊接为研究对象,研制双层气体保护的局部干法水下TIG旋转焊枪,运动轨迹通过直流电机带动钨极绕固定直径转动实现.对核级材料Z2CN19-10控氮奥氏体不锈钢进行焊接,研究局部干法水下TIG焊接焊缝成形,优化工艺参数,结合... 详细信息

以核电厂定位销水下焊接为研究对象,研制双层气体保护的局部干法水下TIG旋转焊枪,运动轨迹通过直流电机带动钨极绕固定直径转动实现.对核级材料Z2CN19-10控氮奥氏体不锈钢进行焊接,研究局部干法水下TIG焊接焊缝成形,优化工艺参数,结合热循环曲线及电弧形态,分析焊接接头显微组织及力学性能.结果表明,当焊枪的内层和外层保护气均通氩气时,焊缝成形良好,电弧形态稳定;增大焊接电流或减小焊接速度均使焊缝熔深增大,熔宽增大;对比水下焊接接头和陆上焊接接头发现,水的快速冷却作用会促使熔合线附近的铁素体的形态由树枝状转变为板条状,奥氏体含量减少,焊缝中心晶粒细化;水下焊接接头的显微硬度和力学性能略高于陆上焊接接头.

关键词：水下局部干法焊接 TIG焊接控氮奥氏体不锈钢焊缝成形组织性能

中部槽构件摆动电弧窄间隙GMAW焊接接头组织及性能研究

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电焊机 2024年第3期54卷 54-59页

作者：董曼淑孙清洁刘进德彭春涛陈兵宁夏天地奔牛实业集团有限公司宁夏石嘴山753001 哈尔滨工业大学(威海) 山东威海264209

采用摆动电弧窄间隙GMAW对中部槽所用50 mm厚ZG/NM异种钢组合进行了非对称填充式双面焊接。焊后在垂直于焊缝方向切取金相试样进行微观组织观察,同时取样进行力学性能测试,包括硬度测试和拉伸试验。试验结果表明:摆动电弧GMAW有效抑制... 详细信息

采用摆动电弧窄间隙GMAW对中部槽所用50 mm厚ZG/NM异种钢组合进行了非对称填充式双面焊接。焊后在垂直于焊缝方向切取金相试样进行微观组织观察,同时取样进行力学性能测试,包括硬度测试和拉伸试验。试验结果表明:摆动电弧GMAW有效抑制了侧壁未熔合缺陷,未出现裂纹;不同填充层由于焊接规范差异,导致组织有所不同;所表征各填充层拉伸性能表现良好,与填充金属性能相当,其中深U型一侧底层强度最高,单道V型填充层强度介于U型顶部与底部之间;接头填充金属的硬度随位置发生变化,从U型一侧到V型一侧,硬度值逐渐降低。不同填充层,母材硬度值最高,填充金属硬度值最低,接头强度与硬度的差异主要归因于焊缝金属中铁素体的含量与形态。

关键词：中部槽异种钢焊接窄间隙坡口摆动电弧热输入铁素体

Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway

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Neural Regeneration Research 2024年第8期19卷 1802-1811页

作者： Fudong Li Xiaofei sun Kaiqiang sun Fanqi Kong Xin Jiang qingjie Kong Department of Orthopedics Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Orthopedic Surgery Spine CenterShanghai Changzheng HospitalNaval Medical UniversityShanghaiChina Department of Orthopedic Surgery Naval Medical CenterNaval Medical UniversityShanghaiChina Department of Anesthesiology Shanghai Changzheng HospitalNaval Medical UniversityShanghaiChina

Spinal cord injury-induced motor dysfunction is associated with *** have shown that the triterpenoid lupenone,a natural product found in various plants,has a remarkable anti-inflammatory effect in the context of chronic ***,the effects of lupenone on acute inflammation induced by spinal cord injury remain *** this study,we established an impact-induced mouse model of spinal cord injury,and then treated the injured mice with lupenone(8 mg/kg,twice a day)by intrape ritoneal *** also treated BV2 cells with lipopolysaccharide and adenosine5’-triphosphate to simulate the inflammatory response after spinal cord *** res ults showed that lupenone reduced IKBa activation and p65 nuclear translocation,inhibited NLRP3 inflammasome function by modulating nuclear factor kappa B,and enhanced the conve rsion of proinflammatory M1 mic roglial cells into anti-inflammatory M2 microglial ***,lupenone decreased NLRP3 inflammasome activation,NLRP3-induced mic roglial cell polarization,and microglia pyroptosis by inhibiting the nuclear factor kappa B *** findings suggest that lupenone protects against spinal cord injury by inhibiting inflammasomes.

关键词： inflammasome inflammation lupenone microglia polarization pyroptosis spinal cord injury

2013—2022年河南省开封市HIV/AIDS病例抗病毒治疗效果及影响因素

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现代疾病预防控制 2024年第8期35卷 626-630页

作者：贠赟杨爽孙清洁韩丹王亚辉开封市疾病预防控制中心河南开封475000

目的分析开封市艾滋病病毒感染者/艾滋病患者(HIV/AIDS)抗病毒治疗后病毒载量结果及其影响因素。方法采用回顾性研究方法,通过艾滋病防治基本信息系统收集2013年1月1日—2022年12月31日开封市15岁及以上HIV/AIDS病例相关信息,分析病毒... 详细信息

目的分析开封市艾滋病病毒感染者/艾滋病患者(HIV/AIDS)抗病毒治疗后病毒载量结果及其影响因素。方法采用回顾性研究方法,通过艾滋病防治基本信息系统收集2013年1月1日—2022年12月31日开封市15岁及以上HIV/AIDS病例相关信息,分析病毒载量结果及影响因素。结果在纳入分析的1264例病例中,经过抗病毒治疗,病毒载量12个月[以≤1个月为参照,>12个月的OR值(95%CI)为2.436(1.363~4.355)]发生病毒学治疗失败的风险更高;治疗时间1~5年[以5年的OR值(95%CI)分别为0.196(0.111~0.346)、0.190(0.108~0.335)、0.127(0.072~0.222)]发生病毒学治疗失败的风险更低。结论开封市HIV/AIDS病例抗病毒治疗效果较好,应加大宣传,提高早期发现能力,关注40岁以上患者,定期随访检测,加强医患沟通,确保患者得到长期规范的治疗。

关键词： HIV/AIDS 抗病毒治疗病毒载量影响因素

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Effects of simulated gut pH environment on bacterial composition and pheromone production of Dendroctonus valens

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Insect Science 2024年第1期31卷 225-235页

作者： qingjie Cao Yu Zhao Tuuli-Marjaana Koski Huiping Li Jianghua sun College of Forestry Hebei Agricultural UniversityBaodingHebei ProvinceChina State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijingChina College of Life Science/Hebei Basic Science Center for Biotic Interactions Institute of Life Science and Green DevelopmentHebei UniversityBaodingHebei ProvinceChina

Bark beetles are an economically and ecologically important insect group,with aggregation behavior and thus host colonization success depends on pheromone-mediated *** some species,such as the major invasive forest pest in China,red turpentine beetle(Dendroctonus valens),gut microbiota participates in pheromone production by converting tree monoterpenes into pheromone ***,how variation in gut microenvironment,such as pH,affects the gut microbial composition,and consequently pheromone production,is *** this study,we fed wild caught *** with 3 different pH media(main host diet with natural pH of 4.7;a mildly acidic diet with pH 6 mimicking the beetle gut pH;and highly acidic diet with pH 4),and measured their effects on the gut pH,bacterial community and production of the main aggregation and anti-aggregation pheromone(verbenone).We further tested the verbenone production capacity of 2 gut bacterial isolates in different pH environments(pH 6 and 4).Compared to natural state or main host diet,feeding on less acidic diet(pH 6)diluted the acidity of the gut,whereas feeding on highly acidic diet(pH 4)enhanced *** changes in gut pH reduced the abundance of dominant bacterial genera,resulting in decreased verbenone ***,the highest pheromone conversion rate of the bacterial isolates was observed in pH mimicking the acidity in beetle *** together,these results indicate that changes in gut pH can affect gut microbiota composition and pheromone production,and may therefore have the potential to affect host colonization behavior.

关键词： Dendroctonus valens gut bacteria gut pH verbenone

Peanut proteins:Extraction,modifications,and applications:A comprehensive review

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粮油科技:英文版 2023年第3期6卷 135-147页

作者： Song Cui David Julian McClements Xingfeng Xu Bo Jiao Liyang Zhou Hualu Zhou Liu Xiong Qiang Wang qingjie sun Lei Dai College of Food Science and Engineering Qingdao Agricultural UniversityChina Qingdao Special Food Research Institute Qingdao 266109China Department of Food Science University of Massachusetts Amherst AmherstMA 01003USA Institute of Food Science and Technology Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products ProcessingMinistry of Agriculture and Rural AffairsBeijing 100193China

As naturally sourced proteins,peanut proteins have garnered significant attention from the food industry,owing to their numerous advantages,such as easy extraction,non-pungency,and high ***,peanut proteins are highly digestible in the gastrointestinal tract and boast a high net protein utilization rate,making them an appealing protein source in food products and a promising alternative to animal *** this paper,the recent works on the extraction method,modification method,and application of peanut proteins were *** advantages and disadvantages of current extraction and modification were *** updated information about peanut protein research was *** on these,the prospection of peanut proteins research was presented,which may be instructive for future research in this *** research is still needed for accessible modification methods to develop the functional properties of peanut proteins.

关键词： Peanut protein Composition Extraction methods Modifications Applications Plant-based foods

Synthesis,structure,and thermal expansion in CaZrF6 with two polymorphs

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Nano Research 2024年第9期17卷 8618-8626页

作者： Peixian Zhang Yongqiang Qiao Kaiyue Zhao qingjie Wang Huan Zhao Juan Guo Erjun Liang Tao sun Jiangwei Zhang Qilong Gao Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China College of Energy Materials and Chemistry Inner Mongolia UniversityHohhot 010021China First Affiliated Hospital of Dalian Medical University 222 Zhongshan RoadDalian 116011China Ordos Laboratory Ordos 017000China

Due to the high structural flexibility and controllable thermal expansion,cubic double ReO_(3)-type negative thermal expansion(NTE)fluorides provide a solution for solving the prominent phenomenon of thermal expansion mismatch between ***,the expensive raw materials and complex synthesis steps limit its practical *** this work,we have designed a more advantageous method for the synthesis of NTE material CaZrF6,and it is expected to be generalized to the synthesis of other double ReO_(3)-***,a new orthorhombic phase CaZrF6 has been synthesized via this method in a lower *** the strong isotropic NTE of the cubic phase CaZrF6,the orthorhombic phase shows the strong anisotropic positive thermal expansion(PTE).The combined analysis of temperature-dependent X-ray diffraction(XRD),Raman spectra,and first-principles calculations shows that the low frequency phonon vibration mode with negative Grüneisen parameter in cubic CaZrF6 are strongly correlated with the transverse thermal vibration of F atoms and dominates the NTE of the material.

关键词： negative thermal expansion fluorides polymorph lattice dynamics first principles calculations

Effect of Bath pH on the Squareness of Electroless CoNiWP Magnetic Films

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Journal of Materials Science & Technology 2008年第5期24卷 712-714页

作者： Haibin CHENG Shuai XU Wenyu ZHAO Suling ZHAO Pengcheng ZHAI Zhigang sunand qingjie ZHANGt Pengcheng ZHAI Zhigang sun qingjie ZHANG State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan 430070 China

Electroless CoNiWP magnetic films were prepared by varying the bath pH and then characterized by energy dispersive X-ray analysis, X-ray diffraction and magnetic force microscopy, it has been found that the microstructure and the magnetic properties of films were influenced greatly by the bath pH. At the bath pH 8.06, the grain size and coercivity of the films reach maximuml while the squareness （Mr/Ms） of MH curves reaches minimum. The Henkel plots indicates that the exchange-coupling interaction is very weak at this pH, which may be caused by phase-separation and large grain size, and then results in the lowest squareness. At pH above 8.5, obvious exchange-coupling interaction is observed because of the inexistence of phase-separation and the refinement of grain size.

关键词： CoNiWP magnetic film Bath pH Squareness Exchange-coupling interaction

兼具抗氧化及抗菌活性的玉米醇溶蛋白肽制备及其乳化特性

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食品科学 2022年第11期43卷 57-66页

作者：唐文婷孙玥孙庆杰王洪彩蒲传奋青岛农业大学食品科学与工程学院山东青岛266109 山东禹王生态食业有限公司山东德州251200

采用胰蛋白酶和木瓜蛋白酶分别水解玉米醇溶蛋白,对其水解产物进行抗氧化、抗菌及乳化活性分析。针对具有较好双抗活性及乳化性能的木瓜蛋白酶水解组分,进一步采用ÄKTA蛋白纯化系统及反相高效液相色谱分离得到纯化组分。通过基质辅助激... 详细信息

采用胰蛋白酶和木瓜蛋白酶分别水解玉米醇溶蛋白,对其水解产物进行抗氧化、抗菌及乳化活性分析。针对具有较好双抗活性及乳化性能的木瓜蛋白酶水解组分,进一步采用ÄKTA蛋白纯化系统及反相高效液相色谱分离得到纯化组分。通过基质辅助激光解析电离四极杆飞行时间质谱对纯化所得肽进行氨基酸序列分析,得出其氨基酸序列为LLAH。玉米醇溶蛋白水解所得LLAH和化学合成LLAH表现出相当的1,1-二苯基-2-三硝基苯肼(1,1-diphenyl-2-picrylhydrazyl,DPPH)自由基、2,2’-联氮-双(3-乙基苯并噻唑啉-6-磺酸)(2,2’-azinobis-(3-ethylbenzothiazoline-6-sulphonic acid),ABTS)阳离子自由基清除活性以及铁离子还原能力和乳化能力。两种LLAH均能抑制大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌和单核细胞增生李斯特菌的生长。LLAH稳定的乳液平均粒径为(263.4±3.5)nm,低于吐温-80稳定的乳液平均粒径((286.8±3.5)nm),前者的贮藏稳定性和氧化稳定性均高于吐温-80稳定的乳液,且对上述4种受试菌株均表现出抑菌效果。LLAH的抗菌和抗氧化活性对其稳定乳液的稳定性具有积极贡献。研究结果对于开发新型玉米醇溶蛋白肽基功能性食品配料具有一定的参考价值。

关键词：抗氧化活性抗菌活性玉米醇溶蛋白肽乳液