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Genome-Wide Analysis of Snapdragon WRKY and VQ Gene Families and Their Expression in Response to Drought and Cold Stresses

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Phyton-International Journal of Experimental Botany 2022年第4期91卷 773-789页

作者： Huaqiao Ding Lihui mao qingcheng Zou Wei Hu Xuerui Cao Qing Dong Zhejiang Institute of Landscape Plants and Flowers Hangzhou311251China

Snapdragon(Antirrhinum majus)is one of the most widely cultivated grass flowers in the world.WRKY transcription factors,VQ proteins and their interactions play crucial roles in plant response to abiotic stresses.However,little is known about WRKY and VQ gene families in snapdragon.In the present study,WRKY and VQ genes and their interactions were comprehensively analyzed in snapdragon using bioinformatics approaches,and their expression in response to drought and cold stresses was examined using real-time PCR.A total of 67 AmWRKY genes were identified in snapdragon,which were classified into different groups or subgroups based on phylogenetic analysis.Members in the same group or sub-groups exhibited similar exon-intron structure and conserved motifs distribution.Among these WRKY genes,16 and 22 genes were found to differentially express under drought and cold stresses,respectively.A total of 32 AmVQ genes were identified,of which 10 and 18 were found to differentially express under drought and cold stresses,respectively.The WRKY-VQ or WRKY-WRKY interaction relationships were predicted for 11 cold-responsive genes,suggesting that they might exist in the same response pathway to cold stress.These results lay a foundation for further studies on roles of WRKY and VQ genes and their interactions in regulating abiotic responses in snapdragon.

关键词： Snapdragon WRKY genes family VQ genes family gene expression abiotic stress

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吸入电焊烟尘致大鼠肺纤维化作用研究

卫生研究 1989年第5期18卷 1-4页

作者：邢康吉邹昌淇袁艳华杜庆成侯瑞玺毛宗数中国预防医学科学院劳动卫生与职业病研究所大连造船厂职业病科

本实验采用国内常用的低氢型碱性焊条结507和钛钙型酸性焊条结422两种焊条的烟尘进行静式吸入染尘,烟尘浓度分别为50mg/m^3和200mg/m^3。实验结果表明两种焊条都能引起全肺胶原蛋白含量的增高。病理观察在染尘后3个月尘细胞灶内可见到... 详细信息

本实验采用国内常用的低氢型碱性焊条结507和钛钙型酸性焊条结422两种焊条的烟尘进行静式吸入染尘,烟尘浓度分别为50mg/m^3和200mg/m^3。实验结果表明两种焊条都能引起全肺胶原蛋白含量的增高。病理观察在染尘后3个月尘细胞灶内可见到少量网织纤维,染尘6个月(200mg/m^3浓度组)和12个月(50mg/m^3浓度组)在尘细胞灶周围出现少量纤细的胶原纤维。以上结果以结507-200mg/m^3浓度组较结422组明显。各脏器组织元素含量分析表明,肺内铁、锰的含量明显高于正常对照组。

关键词：尘肺电焊烟坐肺纤维化电焊工

Traumatic brain injury stimulates sympathetic tone-mediated bone marrow myelopoiesis to favor fracture healing

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Signal Transduction and Targeted Therapy 2023年第8期8卷 3751-3767页

作者： Weijian Liu Wei Chen mao Xie Chao Chen Zengwu Shao Yiran Zhang Haiyue Zhao qingcheng Song Hongzhi Hu Xin Xing Xianyi Cai Xiangtian Deng Xinyan Li Peng Wang Guohui Liu Liming Xiong Xiao Lv Yingze Zhang Department of Orthopaedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Orthopaedic Surgery The Third Hospital of Hebei Medical UniversityShijiazhuang 050051China School of Medicine Nankai UniversityTianjin 300071China NHC Key Laboratory of Intelligent Orthopeadic Equipment Third Hospital of Hebei Medical UniversityShijiazhuang 050051China Animal Center of Hebei Ex&In vivo Biotechnology Shijiazhuang 050051China Department of Physiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Traumatic brain injury(TBI)accelerates fracture healing,but the underlying mechanism remains largely unknown.Accumulating evidence indicates that the central nervous system(CNS)plays a pivotal role in regulating immune system and skeletal homeostasis.However,the impact of CNS injury on hematopoiesis commitment was overlooked.Here,we found that the dramatically elevated sympathetic tone accompanied with TBI-accelerated fracture healing;chemical sympathectomy blocks TBIinduced fracture healing.TBI-induced hypersensitivity of adrenergic signaling promotes the proliferation of bone marrow hematopoietic stem cells(HSCs)and swiftly skews HSCs toward anti-inflammation myeloid cells within 14 days,which favor fracture healing.Knockout ofβ3-orβ2-adrenergic receptor(AR)eliminate TBI-mediated anti-inflammation macrophage expansion and TBIaccelerated fracture healing.RNA sequencing of bone marrow cells revealed that Adrb2 and Adrb3 maintain proliferation and commitment of immune cells.Importantly,flow cytometry confirmed that deletion ofβ2-AR inhibits M2 polarization of macrophages at 7th day and 14th day;and TBI-induced HSCs proliferation was impaired inβ3-AR knockout mice.Moreover,β3-andβ2-AR agonists synergistically promote infiltration of M2 macrophages in callus and accelerate bone healing process.Thus,we conclude that TBI accelerates bone formation during early stage of fracture healing process by shaping the anti-inflammation environment in the bone marrow.These results implicate that the adrenergic signals could serve as potential targets for fracture management.

关键词： healing inflammation Traumatic

Defect evolution in GaN thin film heterogeneously integrated with CMOS-compatible Si(100) substrate by ion-cutting technology

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Science China(Information Sciences) 2023年第11期66卷 313-314页

作者： Hangning SHI Ailun YI Jiaxin DING Xudong LIU qingcheng QIN Juemin YI Junjie HU Miao WANG Demin CAI Jianfeng WANG Ke XU Fengwen MU Tadatomo SUGA René HELLER mao WANG Shengqiang ZHOU Wenhui XU Kai HUANG Tiangui YOU Xin OU State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences University of Chinese Academy of Sciences School of Materials and Chemistry University of Shanghai for Science and Technology Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou Nanowin Science and Technology Co. Ltd. SABers Co. Ltd. Collaborative Research Center Meisei University Helmholtz-Zentrum Dresden-Rossendorf Institute of Ion Beam Physics and Materials Research College of Physics and Electronic Engineering Sichuan Normal University

Ion-cutting technology is an ingenious solution to the highquality heterogeneous integration of Ga N thin films with CMOS-compatible Si(100) substrate, which provides a platform to combine Ga N-based optoelectronics, high-frequency and high-power electronics with digital signal processing,logic computation, and control of Si(100) CMOS [1].

关键词： Gallium nitride

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基于体视学原理的煤岩裂隙三维表征试验研究

岩石力学与工程学报 2014年第6期33卷 1227-1232页

作者：张青成左建民毛灵涛中国矿业大学力学与建筑工程学院北京100083 北京赛博思建筑设计有限公司北京100044

基于体视学原理,运用工业CT试验系统对煤样进行单轴加载扫描试验。对得到的CT扫描图像采用不同阈值求取其裂隙张量特征值平方和的曲线,选取曲线图拐点处所对应的阈值作为图像二值化的阈值,并验证该阈值是计算二阶张量的最佳阈值。同时... 详细信息

基于体视学原理,运用工业CT试验系统对煤样进行单轴加载扫描试验。对得到的CT扫描图像采用不同阈值求取其裂隙张量特征值平方和的曲线,选取曲线图拐点处所对应的阈值作为图像二值化的阈值,并验证该阈值是计算二阶张量的最佳阈值。同时实现体视学中对二值化后的图像测线及特征区域参数的提取,提出特征值平方和的概念作为描述煤样破损程度的参数。在从三维角度重构出的裂隙煤样中,选取3个正交面构造出二阶张量特征值平方和与孔隙率之间的关系,为进一步从三维角度描述煤样裂隙损伤奠定基础。

关键词：岩石力学体视学煤岩 CT图像裂隙张量三维表征

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观赏植物姜荷花研究进展

中国野生植物资源 2022年第11期41卷 66-68,73页

作者：毛俐慧邹清成董青曹雪蕊浙江省园林植物与花卉研究所浙江杭州311251

姜荷花原产于泰国,花型似莲也像郁金,被称为热带郁金,是长江流域夏季很好的花镜植物,也是盆栽和切花市场的新宠。姜荷花引进中国已经有10多年的历史,本研究从资源收集与育种、生产扩繁、生理及分子机理等几个方面综述了姜荷花的研究进展... 详细信息

姜荷花原产于泰国,花型似莲也像郁金,被称为热带郁金,是长江流域夏季很好的花镜植物,也是盆栽和切花市场的新宠。姜荷花引进中国已经有10多年的历史,本研究从资源收集与育种、生产扩繁、生理及分子机理等几个方面综述了姜荷花的研究进展,分析了姜荷花产业尚存在问题及未来的研究方向。

关键词：姜荷花组织培养品种耐寒性

Mg-Y共掺杂高电压钴酸锂正极材料的合成及其性能研究

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稀有金属材料与工程 2021年第3期50卷 1026-1031页

作者：阮丁山李玲杜柯毛林林李斌方庆城徐振鹏胡国荣中南大学冶金与环境学院湖南长沙410083 广东邦普循环科技有限公司广东佛山528000

将Co_(3)O_(4)、Li_(2)CO_(3)、Mg(OH)_2和Y_(2)O_(3)按一定化学计量比称取并混合均匀后,采用高温固相法合成LiCo_(1-x-y)Mg_(x)Y_(y)O_(2)正极材料并探究了Mg-Y共掺杂对钴酸锂高电压性能的影响。采用X射线衍射(XRD)和扫描电镜(SEM)分别表征其晶体结构和形貌。LiCo_(1-x-y)Mg_(x)Y_(y)O_(2)正极材料高电压性能测试结果表明选择Mg掺杂量为0.2%(质量分数),当Y的掺杂量为0.10%(质量分数)时,在3.0~4.6 V电压范围内0.5 C倍率下的初始放电比容量为212 mAh/g,循环50周的容量保持率为96.3%。4 C大倍率下,未掺杂Y元素样品容量保持率为54.9%,相比之下Y掺杂后容量保持率提高为60.4%。

关键词：锂离子电池正极材料钴酸锂掺杂改性

姜荷花观赏苞片衰老生理及永生花制作技术研究

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现代农业科技 2023年第1期 106-110页

作者：董青曹雪蕊韩亚飞胡伟毛俐慧邹清成田丹青浙江省园林植物与花卉研究所浙江杭州311251 邹城市自然资源和规划局山东邹城273500

本文以姜荷花品种清迈粉为研究对象,对姜荷花观赏苞片衰老生理进行了研究,并探讨了姜荷花永生花制作技术。结果表明:随着观赏苞片的衰败,观赏苞片持续受到活性氧伤害,在观赏苞片全部展开达到盛花期时,超氧化物歧化酶清除超氧根离子的能... 详细信息

本文以姜荷花品种清迈粉为研究对象,对姜荷花观赏苞片衰老生理进行了研究,并探讨了姜荷花永生花制作技术。结果表明:随着观赏苞片的衰败,观赏苞片持续受到活性氧伤害,在观赏苞片全部展开达到盛花期时,超氧化物歧化酶清除超氧根离子的能力达到顶峰。观赏苞片初花期过氧化氢酶在清除过氧化氢中起着重要作用,观赏苞片衰败期过氧化物酶在清除过氧化氢中起着重要作用。盛花期,观赏苞片中脯氨酸含量最高,超氧化物歧化酶活性最强,观赏苞片耐逆性最佳。姜荷花永生花制作技术的出现既可丰富永生花产品种类,又可增加花卉产业经济效益,实际应用价值较高。

关键词：姜荷花衰老生理永生花制作技术

从易水学派调补脾胃学术思想探析咳喘辨治经验

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河北中医 2021年第10期43卷 1589-1592,1597页

作者：蔡青城毛玉璇常甜王艳君河北中医学院附属医院针灸科河北石家庄050011

易水学派精于脏腑辨证论治,在先后天元气论的认识基础上,重视后天元气之本在治疗咳喘中的重要性,同时强调脾胃为人体气机升降枢纽,脾胃受损是导致肺失宣降的关键病因之一。易水学派将脾胃学说运用于咳喘的临床辨治中,以补脾胃、调气机... 详细信息

易水学派精于脏腑辨证论治,在先后天元气论的认识基础上,重视后天元气之本在治疗咳喘中的重要性,同时强调脾胃为人体气机升降枢纽,脾胃受损是导致肺失宣降的关键病因之一。易水学派将脾胃学说运用于咳喘的临床辨治中,以补脾胃、调气机、培土生金为其治疗咳喘的治疗思路,灵活运用甘温、升浮之药。通过梳理易水学派对咳喘病因病机的认识及辨治咳喘的治则治法经验,分析其代表医案,进一步挖掘易水学派调补脾胃辨治咳喘的学术观点及组方遣药规律,为临床辨治咳喘提供更多思路及参考依据。

关键词：咳喘易水学派调理脾胃