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Update Knowledge Assessment and Influencing Predictor of Female Fertility Preservation in Oncologists

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Current Medical Science 2022年第4期42卷 824-831页

作者： Li-xia ZHU Lei JIN Jing-hang JIANG Liu YANG Zi-shui FANG Meng WANG Ying xiAO qing-song xi Reproductive Medicine Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Reproductive Medicine Center Jingmen Second People's HospitalJingmen 448000China Cancer Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Objective:This study aims to offer an update assessment of the knowledge of Chinese oncologists on female fertility preservation,and identify the determinants that influence the implementation of fertility ***:A total of 713 Chinese oncologists with different specialties completed the online self-report questionnaire to assess their understanding of fertility risks in cancer treatment,knowledge on female fertility preservation,and perceptions on the barriers in referring patients for fertility ***:Although most oncologists were familiar with fertility risk in cancer treatment,half of them lacked the knowledge for reproduction and preservation *** the multivariable model,oncologists in a hospital with a specialized reproductive institution,positive precaution for fertility risk,and fertility preservation discussion with patients were significantly correlated with the possibility of fertility preservation ***:The intervention targets based on the update evaluation and identified influencing determinants will be helpful for all the oncofertility researchers,oncologists and institutions in future efforts for well-established female fertility preservation services.

关键词： fertility preservation oncologists female infertility neoplasms

Prescribed Performance Tracking Control of Time-Delay Nonlinear Systems With Output Constraints

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IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1557-1565页

作者： Jin-xi Zhang Kai-Di Xu qing-Guo Wang IEEE the State Key Laboratory of Synthetical Automation for Process Industries Northeastern UniversityShenyang 110819China Institute of Artificial Intelligence and Future Networks Beijing Normal UniversityZhuhai 519087 Guangdong Key Laboratory of Artificial Intelligence and Multi-Modal Data Processing Beijing Normal University-Hong Kong Baptist University United International CollegeZhuhai 519087

The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requirements, i.e., boundedness and the local Lipschitz condition, are assumed for the allowable time delays. Moreover, we focus on the case where the reference is unknown beforehand, which renders the standard prescribed performance control designs under output constraints infeasible. To conquer these challenges, a novel robust prescribed performance control approach is put forward in this ***, a reverse tuning function is skillfully constructed and automatically generates a performance envelop for the tracking error. In addition, a unified performance analysis framework based on proof by contradiction and the barrier function is established to reveal the inherent robustness of the control system against the time delays. It turns out that the system output tracks the reference with a preassigned settling time and good accuracy,without constraint violations. A comparative simulation on a two-stage chemical reactor is carried out to illustrate the above theoretical findings.

关键词： Nonlinear systems output constraints prescribed performance reference tracking time delays

A theoretical model for impact protection of flexible polymer material

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Theoretical & Applied Mechanics Letters 2024年第3期14卷 217-226页

作者： Huifeng xi Hui Pan song Chen Heng xiao MOE Key Lab of Disaster Forecast and Control in Engineering School of Machanics and Construction EngineeringJinan UniversityGuangzhou 510632China Doctor Workstation of Xuwen County Guangdong Hydropower Energy Co. Ltd.Xuwen 524100China

The relationship between the protective performance of flexible polymer material and material parameters(elasticmodulus,viscosity coefficient)is explored,an impact collision motion equation between two bodies is establishedfrom the viscoelastic material constitutive,and the relationship between the kinematic response and the materialparameters is *** on the Kelvin constitutive model,a theoretical model for impact between the pro-tective body and the protected body is established,then the dynamic response is *** feasibility of themodel was verified by drop hammer experiment,and the material parameters(elastic modulus,viscosity coeffi-cient)were obtained by *** model is discretized and the relationship between local impact response andmaterial parameters is *** discussion results on the relationship between the impact response and theprotective material performance indicate that adjusting the elastic modulus,viscosity coefficient,and thicknessof the protective material can effectively improve protective effect.

关键词： Flexible polymer material Viscoelastic material Kelvin modelDynamic response Elastic modulus and viscosity coefficient

A digital twins enabled underwater intelligent internet vehicle path planning system via reinforcement learning and edge computing

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Digital Communications and Networks 2024年第2期10卷 282-291页

作者： Jiachen Yang Meng xi Jiabao Wen Yang Li Houbing Herbert song School of Electrical and Information Engineering Tianjin UniversityTianjin300072China Security and Optimization for Networked Globe Laboratory(song Lab) Embry-Riddle Aeronautical UniversityDaytona BeachFL32114USA

The Autonomous Underwater Glider(AUG)is a kind of prevailing underwater intelligent internet vehicle and occupies a dominant position in industrial applications,in which path planning is an essential *** to the complexity and variability of the ocean,accurate environment modeling and flexible path planning algorithms are pivotal *** traditional models mainly utilize mathematical functions,which are not complete and *** existing path planning algorithms depend on the environment and lack *** overcome these challenges,we propose a path planning system for underwater intelligent internet *** applies digital twins and sensor data to map the real ocean environment to a virtual digital space,which provides a comprehensive and reliable environment for path *** design a value-based reinforcement learning path planning algorithm and explore the optimal network structure *** path simulation is controlled by a closed-loop model integrated into the terminal vehicle through edge *** integration of state input enriches the learning of neural networks and helps to improve generalization and *** task-related reward function promotes the rapid convergence of the *** experimental results prove that our reinforcement learning based path planning algorithm has great flexibility and can effectively adapt to a variety of different ocean conditions.

关键词： Digital twins Reinforcement learning Edge computing Underwater intelligent internet vehicle Path planning

Effect of Incoming Vortex on Secondary Flows in Turbine Cascades with Planar and Non-Axisymmetric Endwall

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Journal of Thermal Science 2024年第1期33卷 138-157页

作者： CAO Zhiyuan WANG Chuxuan song Zhigao GAO xi ZHAO Wei LIU Bo School of Power and Energy Northwestern Polytechnical UniversityXi'an 710072China National Key Laboratory of Science and Technology on Aerodynamic Design and Research Northwestern Polytechnical UniversityXi'an 710072China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100080China School of Aeronautics and Astronautics University of Chinese Academy of SciencesBeijing 100080China

Non-Axisymmetric Endwall Profiling(NAEP) is commonly utilized in turbines to eliminate secondary ***,most of the NAEP methods consider a single-blade row environment without incorporating the effect of the stage *** paper aims to investigate the influence mechanism of the incoming vortex on the endwall secondary flow structures of NAEP in a highly loaded turbine *** model the incoming vortex in a stage environment,this study considers a half-delta wing as the vortex generator at the upstream of the turbine *** NAEP is then carried out for a highly loaded turbine cascade with an in-house numerical optimization design platform subject to no incoming *** simulation is also carried out under the influence of the incoming vortex for the turbine cascades with both planar and non-axisymmetric *** paper furthers investigated the pitchwise effect of the incoming vortex on the near endwall secondary *** results indicate that the NAEP effectively improves the endwall secondary flow of the turbine cascade,where the total pressure loss coefficient and the secondary kinetic energy(SKE) are reduced by 7.3%,and 45.7%,*** is further seen that with the incoming vortex,the NAEP achieves a considerable control effect on the endwall secondary flow of the turbine *** incoming vortex,the NAEP can still achieve considerable control effect on the endwall secondary flow of the turbine cascade;the averaged reductions of loss coefficient and SKE are 7.8% and 14.2%,*** some pitchwise locations,incoming vortex can suppress the convection of cross-passage flow toward the suction corner greatly and reduce the loss coefficient of the baseline *** incoming vortex at 4/7 pitch impinged right at the blade leading edge,leading to the generation of low-momentum fluid,which increased the size and the strength of the horseshoe *** all the pitchwise locations,NAEP can suppress the seco

关键词： non-axisymmetric endwall secondary flow incoming vortex passage vortex stage environment

Pyruvate kinase M in germ cells is essential for sperm motility and male fertility but not spermatogenesis

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Asian Journal of Andrology 2024年第2期26卷 212-219页

作者： Gao-qing Qian xiao-Chen Wang xi Zhang Bin Shen Qiang Liu State Key Laboratory of Reproductive Medicine and Offspring Health Nanjing Medical UniversityNanjing 211166China Shanghai Key Laboratory of Reproductive Medicine Department of HistoembryologyGenetics and Developmental BiologyShanghai Jiao Tong University School of MedicineShanghai 200025China State Key Laboratory of Molecular Biology Shanghai Key Laboratory of Molecular AndrologyShanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China

Male germ cells employ specific metabolic pathways throughout their developmental *** a previous study,we discovered heightened expression of pyruvate kinase M(PKM),a pivotal glycolytic enzyme,in spermatogonia and *** gain deeper insights into PKM's roles in spermatogenesis,sperm function,and male fertility,we engineered a conditional-knockout mouse model(Pkm-vkO mice)to selectively disrupt the Pkm gene within germ *** maintaining regular testicular histology and sperm morphology,the male Pkm-vko mice were infertility,characterized by significant impairments in sperm motility and adenosine triphosphate(ATP)*** addition,Pkm-null spermatozoa exhibited similar deficits in protein tyrosine phosphorylation linked to capacitation,as well as compromised performance in in vitro fertilization *** conclude,PKM's presence is not obligatory for the entirety of spermatogenesis in male germ cells;however,it emerges as a critical factor influencing sperm motility and overall male fertility.

关键词： glycolysis male fertility pyruvate kinase M sperm motility spermatogenesis

Compound extreme inundation risk of coastal wetlands caused by climate change and anthropogenic activities in the Yellow River Delta,China

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Advances in Climate Change Research 2024年第1期15卷 134-147页

作者： xiao-Li WANG Ai-qing FENG xi-Yong HOU qing-Chen CHAO Bai-Yuan song Yu-Bin LIU Qi-Guang WANG He XU Yu-xin ZHANG Dong Li Li-Jie DONG Yu GUO CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation Yantai Institute of Coastal Zone ResearchChinese Academy of SciencesYantai 264003China Shandong Key Laboratory of Coastal Environmental Processes Yantai 264003China China Meteorological Administration Key Laboratory for Climate Prediction Studies National Climate CentreBeijing 100081China Tongji Urban Planning Design Research Institute Shanghai 200092China School of Geography and Tourism Qilu Normal UniversityJinan 250200China China Meteorological Administration Training Centre China Meteorological AdministrationBeijing 10008China University of Chinese Academy of Sciences Beijing 100049China Marine Science and Technology College Zhejiang Ocean UniversityZhoushan 316022China

The coastal wetlands of the Yellow River Delta(YRD)in China are crucial for their valuable resources,environmental significance,and economic ***,these wetlands are also vulnerable to the dual threats of climate change and human *** substantial attention to the historical shifts in YRD's coastal wetlands,uncertainties remain regarding their future trajectory in the face of compound risks from climate change and anthropogenic *** on a range of remote sensing data sources,this study undertakes a comprehensive investigation into the evolution of YRD's coastal wetlands between 2000 and ***,the potential fate of coastal wetlands is thoroughly analyzed through the Land Use/Cover Change(LUCC)simulation using System Dynamic-Future Land Use Simulation(SD-FLUS)model and the extreme water levels projection integrated future sea-level rise,storm surge,and astronomical high tide in 2030,2050,and 2100 under scenarios of SSP1-2.6,SSP2-4.5,and *** revealed that YRD's coastal wetlands underwent a marked reduction,shrinking by 1688.72 km²from 2000 to *** decline was mostly attributed to the substantial expansion in the areas of artificial wetlands(increasing by 823.78 km2),construction land(increasing by 767.71 km²),and shallow water(increasing by 274.58 km²).Looking ahead to 2030-2100,the fate of coastal wetlands appears to diverge based on different *** the SSP1-2.6 scenario,the area of coastal wetland is projected to experience considerable *** contrast,the SSP5-8.5 scenario anticipates a notable decrease in coastal *** to the inundated area suffered from the current extreme water levels,the study projects a decrease of 6.8%-10.6%in submerged coastal wetlands by 2030 and 9.4%-18.2%by 2050 across all *** 2100,these percentages are projected to decrease by 0.4%(SSP2-4.5)and 27.1%(SSP5-8.5),but increase by 35.7%(SSP1-2.6).Results suggest that coastal wetlands in th

关键词： Climate change Anthropogenic activities Compound extreme risk Coastal wetlands Yellow River Delta

Study on a probabilistic algorithm for the forming and 3D characterization of special-shaped surfaces under profile grinding

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Advances in Manufacturing 2024年第2期12卷 288-299页

作者： Zhao-qing Zhang Kai-Ning Shi Yao-Yao Shi Yi-Hui song Zhe He Ya-song Pu School of Mechanical Engineering Northwestern Polytechnical UniversityXi’an710072People’s Republic of China Key Laboratory of High Performance Manufacturing for Aero Engine(Northwestern Polytechnical University) Ministry of Industry and Information TechnologyXi’an710072People’s Republic of China Engineering Research Center of Advanced Manufacturing Technology for Aero Engine(Northwestern Polytechnical University) Ministry of EducationXi’an710072People’s Republic of China

Profile grinding is the most crucial method for the ultra-precision machining of special-shaped ***,profile grinding produces a unique machining profile,and many random factors in the machining process lead to complex surface *** this study,the structural and probabilistic characteristics of the profile grinding of a special-shaped surface were analyzed,and a probabilistic algorithm for the forming and 3D characterization of special-shaped surfaces under profile grinding was *** forming process of a GH738 blade tenon tooth surface was considered as an example to demonstrate the *** comparison results showed that the simulation results had similar surface characteristics to the measurement results,and the relative error range of the 3D roughness parameter was 0.21%–19.76%,indicating an accurate prediction and characterization of the complex special-shaped surface under the action of multiple factors.

关键词： Special-shaped surface Profile grinding Surface morphology 3D characterization

Corrosion evaluation and resistance study of alloys in chloride salts for concentrating solar power plants

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Rare Metals 2024年第3期43卷 1222-1233页

作者： Dong-Mei Han Yong Shuai Bachirou Guene Lougou Bo-xi Geng xi-Bo He Tian-Tian Yan Jia-Meng song School of Energy Science and Engineering Harbin Institute of TechnologyHarbin150001China

Thermal energy storage(TES)systems based on molten salt are widely used in concentrating solar power(CSP)*** investigation of the corrosion behavior of alloy materials in molten salt is crucial for the correct selection of alloy materials and the design of TES *** this study,the corrosion behavior of 304,310S,316,and In625 alloys in molten chloride salts(27 mol%NaCl-22 mol%KCl-51 mol%MgCl,)was *** evolution of mass loss of the alloy samples with corrosion time and temperature and the analysis of the experimental results by scanning electron microscopy(SEM),energy dispersive spectrometer(EDS),and X-ray diffraction(XRD)revealed the corrosion mechanism of the alloy samples in molten chloride *** main factors affecting the corrosion of the alloy samples were further *** was found that the loose multi-layer corrosion was formed on the surface of the corroded alloy samples with the increase in corrosion ***,the experimental *** that Mo played a positive role in improving the corrosion resistance of the alloy samples because the presence of Mo could inhibit the outward diffusion of alloying element *** work enriches the molten salt corrosion database and provides a reference for the selection of alloy materials for TES systems with potential application in CSP plants.

关键词： Thermal energy storage Molten chloride salt Alloy materials Corrosion mechanism Corrosion resistance