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Tetrahedral framework nucleic acids promote the proliferation and differentiation potential of diabetic bone marrow mesenchymal stem cell

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Chinese Chemical Letters 2024年第9期35卷 284-288页

作者： Yanjing Li Jiayin Li Yuqi Chang Yunfeng lin Lei sui Department of Prosthodontics Tianjin Medical University School and Hospital of StomatologyTianjin 300070China State Key Laboratory of Oral Diseases West China Hospital of StomatologySichuan UniversityChengdu 610041China

Diabetes mellitus considerably affects bone marrow mesenchymal stem cells(BMSCs),for example,by inhibiting their proliferation and differentiation potential,which enhances the difficulty in endogenous bone ***,effective strategies for enhancing the functions of BMSCs in diabetes have farreaching consequences for bone healing and regeneration in diabetes *** framework nucleic acids(tFNAs)are nucleic acid nanomaterials that can autonomously enter cells and regulate their *** this study,we evaluated the effects of tFNAs on BMSCs from diabetic *** found that tFNAs could promote the proliferation,migration,and osteogenic differentiation of BMSCs from rats with type 2 diabetes mellitus,and inhibited cell senescence and ***,tFNAs effectively scavenged the accumulated reactive oxygen species and activated the suppressed protein kinase B(Akt)signaling ***,we show that tFNAs can recover the proliferation and osteogenic potential of diabetic BMSCs by alleviating oxidative stress and activating Akt *** study provides a strategy for endogenous bone regeneration in diabetes and also paves the way for exploiting DNA-based nanomaterials in regenerative medicine.

关键词： Bone marrow mesenchymal stem cell Diabetes mellitus DNA-based nanomaterial Tetrahedral framework nucleic acids Endogenous bone regeneration

Diagnostic discrepancy between colposcopy and vaginoscopy:A case report

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World Journal of Clinical Cases 2021年第21期9卷 5943-5947页

作者： qing Li Hong-Wei Zhang Long sui Ke-Qin Hua Diagnosis and Treatment Center of Cervical Disease OBG Hospital of Fudan UniversityShanghai 200000China Department of Gynecology Obstetrics and Gyncology Hospital of Fudan UniversityShanghai 200090China

BACKGROUND Colposcopy currently plays a vital role in the diagnosis and treatment of lower genital *** and biopsy are two key steps in *** the whole transformation zone or all lesions cannot be observed,we judge colposcopy as *** colposcopic examination may lead to the misdiagnosis of more severe *** combination of colposcopy and vaginoscopy may contribute to accurate diagnosis and clinical *** SUMMARY Here,we introduce a case of posthysterectomy deep vaginal apex not fully exposed by colposcopy,and the biopsy result was a vaginal precancerous *** adopted vaginoscopy to extend the observed area and expose the lesion thoroughly,and the biopsy result was vaginal squamous *** The patient received a precise diagnosis and early surgery due to the combination of colposcopy and vaginoscopy.

关键词： Colposcopy Yaginoscopy Cervicoscopy Hysteroscopy Unsatisfactory Discrepancy Case report

Formation Dynamics and Quantitative Prediction of Hydrocarbons of the Superpressure System in the Dongying Sag

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Acta Geologica Sinica(English Edition) 2008年第1期82卷 164-173页

作者： sui Fenggui HAO Xuefeng LIU qing ZHUO Qin＇gong ZHANG Shouchun Geological Scientific Research Institute Shengli Oilfield Company of SINOPEC. Dongying Shandong 257015

Based on the theory of formation dynamics of oil/gas pools, the Dongying sag can be divided into three dynamic systems regarding the accumulation of oil and gas： the superpressure closed system, the semi-closed system and the normal pressure open system. Based on the analysis of genesis of superpressure in the superpressure closed system and the rule of hydrocarbon expulsion, it is found that hydrocarbon generation is related to superpressure, which is the main driving factor of hydrocarbon migration. Micro fractures formed by superpressure are the main channels for hydrocarbon migration. There are three dynamic patterns for hydrocarbon expulsion： free water drainage, hydrocarbon accumulation and drainage through micro fissures. In the superpressure closed system, the oil-driving-water process and oil/gas accumulation were completed in lithologic traps by way of such two dynamic patterns as episodic evolution of superpressure systems and episodic pressure release of faults. The oil-bearing capacity of lithologic traps is intimately related to reservoir-forming dynamic force. Quantitative evaluation of dynamic conditions for pool formation can effectively predict the oil-bearing capability of traps.

关键词： superpressure closed system hydrocarbon expulsion dynamics dynamic patterns for pool formation quantitative prediction Dongying sag

Two new megastigmane O-glucopyranosides from the leaves of Broussonetia papyrifera

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Chinese Chemical Letters 2007年第12期18卷 1518-1520页

作者： Wei Sheng Feng Hong Wei Li Xiao Ke Zheng sui qing Chen Henan College of Traditional Chinese Medicine Zhengzhou 450008 China

Two new megastigmane O-glucopyranosides, named （2R,3R,5R,6S,9R）-3-hydroxy-5,6-epoxy-β-ionol-2-O-β-D-glucopyrano- side （1） and （2R,3R,5R,6S,9R）-3-hydroxyl-5,6-epoxy-acety-β-ionol-2-O-β-D-glucopyranoside （2） together with six known mega- stigmanes, were isolated from the leaves of Broussonetia papyrifera （linn.） Vent. Their structures were established by chemical methods and spectroscopic techniques including 2D NMR.

关键词： Broussonetia papyrifera Megastigmane O-glucopyranosides

Patterned glass ceramic design for high-brightness high-color-quality laser-driven lightings

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Journal of Advanced Ceramics 2022年第6期11卷 862-873页

作者： Qiugui HUANG Hang lin Bo WANG Shisheng lin Pengfei WANG Ping sui Ju XU Yao CHENG Yuansheng WANG Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350007China Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou 350108China School of Applied Physics and Materials Wuyi UniversityJiangmen 529020China

Up-to-date laser-driven lightings confront a challenge of simultaneously achieving good photometric and chromatic ***,the coupling of“patterned package design”and“phosphor wheel”was proposed and demonstrated effectively to deal with this tough issue,based on a new architecture of CaAlSiN3:Eu2+(CASN:Eu)glass ceramic film(GCF)on Y_(3)Al_(5)O_(12):Ce^(3+)(YAG:Ce)GC *** fabricated composite has no interface between the two functional layers and retains the admirable luminescent features from CASN:Eu and YAG:Ce for the microstructural integrity during *** studies on laser-microcrystalline interactions reveal that the luminescence saturation is almost determined by thermal quenching for YAG:Ce,but is ascribed to thermal/intensity quenching which are equally crucial for CASN:*** from the elaborate architecture design,good color chromaticity tunability was obtained,and severe photon reabsorption was ***,accompanied with the rotation induced increase of thermal convection to air and pulse-like excitation,the constructed lighting engine under blue laser driven shows bright white light with luminous flux(LF)higher than 1000 lm,adjustable chromaticity from cool to warm,and improved color rendering index(CRI)approaching to 70.

关键词： laser lightings glass ceramics(GCs) white light garnets nitrides

Yield penalty of maize(Zea mays L.) under heat stress in different growth stages: A review

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Journal of Integrative Agriculture 2022年第9期21卷 2465-2476页

作者： LI Teng ZHANG Xue-peng LIU qing LIU Jin CHEN Yuan-quan sui Peng Key Laboratory of Farming Systems Ministry of Agriculture and Rural Affairs/College of Agronomy and BiotechnologyChina Agricultural UniversityBeijing 100193P.R.China

Maize(Zea mays L.) can exhibit yield penalties as a result of unfavorable changes to growing conditions. The main threat to current and future global maize production is heat stress. Maize may suffer from heat stress in all of the growth stages, either continuously or separately. In order to manage the impact of climate driven heat stress on the different growth stages of maize, there is an urgent need to understand the similarities and differences in how heat stress affects maize growth and yield in the different growth stages. For the purposes of this review, the maize growth cycle was divided into seven growth stages, namely the germination and seedling stage, early ear expansion stage, late vegetative growth stage before flowering, flowering stage, lag phase, effective grain-filling stage, and late grain-filling stage. The main focus of this review is on the yield penalty and the potential physiological changes caused by heat stress in these seven different stages. The commonalities and differences in heat stress related impacts on various physiological processes in the different growth stages are also compared and discussed. Finally, a framework is proposed to describe the main influences on yield components in different stages, which can serve as a useful guide for identifying management interventions to mitigate heat stress related declines in maize yield.

关键词： growth stage heat stress maize yield penalty

Toward a rapid and convenient nanoplastic quantification method in laboratory-scale study based on fluorescence intensity

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Frontiers of Environmental Science & Engineering 2024年第5期18卷 117-126页

作者： Ruiqi Yan Sen lin Qian Ding Lei Zhang Xia Yu Wentao Zhao Qian sui State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process School of Resources and Environmental EngineeringEast China University of Science and TechnologyShanghai200237China State Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and EngineeringTongji UniversityShanghai200092China Shanghai Institute of Pollution Control and Ecological Security Shanghai200092China

The thorough investigation of nanoplastics(NPs)in aqueous environments requires efficient and expeditious quantitative analytical methods that are sensitive to environmentally relevant NP concentrations and convenient to *** analysis-based quantitative methods have been acknowledged as effective and rapid approaches for quantifying NP concentrations in laboratory-scale ***,we compared three commonly used optical response indicators,namely fluorescence intensity(FI),ultraviolet absorbance,and turbidity,to assess their performance in quantifying ***,orthogonal experiments were conducted to evaluate the influence of various water quality parameters on the preferred indicator-based quantification *** results revealed that FI exhibits the highest correlation coefficient(>0.99)with NP ***,the limit of quantification(LOQ)for various types of NPs is exceptionally low,ranging from 0.0089 to 0.0584 mg/L in ultrapure water,well below environmentally relevant *** variations in water quality parameters such as pH,salinity,suspended solids(SS),and humic acid,a robust relationship between detectable FI and NP concentration was ***,an increased matrix,especially SS in water samples,results in an enhanced LOQ for ***,the quantitative method remains applicable in real water bodies,especially in drinking water,with NP LOQ as low as 0.0157–0.0711 mg/*** exceeds the previously reported detectable concentration for 100 nm NPs at 40µg/mL using surface-enhanced Raman *** study confirms the potential of FI as a reliable indicator for the rapid quantification of NPs in aqueous environments,offering substantial advantages in terms of both convenience and cost-effectiveness.

关键词： Nanoplastic quantification Fluorescence intensity Drinking water Limit of quantification(LOQ) Matrix effects

Spatially strain-induced and selective preparation of Mo_(x)N(x=1,2)as a highly effective nanoarchitectonic catalyst for hydrogen evolution reaction in a wide pH range

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Rare Metals 2023年第5期42卷 1446-1452页

作者： Chao Huang Xiao-lin Zhang Jing Tang Dan Li qing-Dong Ruan Liang-Liang Liu Fang-Yu Xiong Bin Wang Yue Xu sui-Han Cui Yang Luo qing-Wei Li Paul K.Chu Department of Physics Department of Materials Science and EngineeringCity University of Hong KongHong Kong999077China Department of Biomedical Engineering City University of Hong KongHong Kong999077China State Key Laboratory of Powder Metallurgy Central South UniversityChangsha410011China School of Mechanical Engineering Liaoning Petrochemical UniversityFushun113001China Advanced Research Institute for Multidisciplinary Science Qilu University of Technology(Shandong Academy of Sciences)Jinan250307China

Developing highly efficient catalysts for the hydrogen evolution reaction(HER)is crucial to commercial water splitting in the global efforts to mitigate fossil fuel combustion and combat global climate *** nitrides(Mo... 详细信息

关键词： catalyst splitting preparation

FLOATING RATE OF FRAZIL ICE PARTICLES IN FLOWING WATER IN BEND CHANNELS——A THREE-DIMENSIONAL NUMERICAL ANALYSIS

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Journal of Hydrodynamics 2010年第1期22卷 19-28页

作者： WANG Jun LI qing-gang sui Jue-yi School of Civil Engineering Hefei University of Technology Hefei 230009 China Environmental Engineering Program University of Northern British Columbia British Columbia Canada V2N4V9

In this article, based on the theory of two-phase flow and laboratory data, a three-dimensionally model is developed to simulate the floating rates of frazil ice particles in water under covered condition. The Lagrangian trajectory method is used in the three dimensional simulation for floating rates of fxazil ice particles along a 180° bend channel. The velocity profiles in longitudinal and transverse directions, the turbulence intensity, and the residual pressure are simulated. Under the condition of gravitational similarity, the simulated floating rates of frazil ice particles in the model bend channel and the prototype bend channels are compared. Results indicate that the profiles for floating rates of ice particles for flows in the model channel are similar to those in the prototype bend channels. The simulated floating rates of ice particles are clearly higher along the convex bank than along the concave bank at each cross section. For the prototype bend channel in a large model scale, the variation of floating rate across each cross section is relatively small.

关键词： frazil ice particles model scale floating rate two-phase flow bend channel ice accumulation (ice jam)