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Laryngopharyngeal reflux disease:Updated examination of mechanisms,pathophysiology,treatment,and association with gastroesophageal reflux disease

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World Journal of Gastroenterology 2024年第16期30卷 2209-2219页

作者： Na Cui Ting Dai Yang Liu Ya-Yu Wang Jia-Yu Lin qing-fan zheng Dong-Dong Zhu Xue-Wei Zhu Department of Otorhinolaryngology Head and Neck Surgery China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Ultrasound China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Gastroenterology China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

Laryngopharyngeal reflux disease(LPRD)is an inflammatory condition in the laryngopharynx and upper aerodigestive tract mucosa caused by reflux of stomach contents beyond the *** commonly presents with symptoms such as hoarseness,cough,sore throat,a feeling of throat obstruction,excessive throat *** complex condition is thought to involve both reflux and reflex mechanisms,but a clear understanding of its molecular mechanisms is still ***,there is no standardized diagnosis or treatment *** strategies for LPRD mainly include lifestyle modifications,proton pump inhibitors and endoscopic *** paper seeks to provide a comprehensive overview of the existing literature regarding the mechanisms,pathophysiology and treatment of *** also provide an in-depth exploration of the association between LPRD and gastroesophageal reflux disease.

关键词： Laryngopharyngeal reflux Gastroesophageal reflux Head neck surgery Laryngitis Otolaryngology

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空间拦截器半实物仿真系统设计

计算机仿真 2023年第12期40卷 74-79页

作者：王婷崔毅楠罗汝斌范青正北京宇航系统工程研究所北京100076

为了精确地评估空间拦截器拦截空间远程目标的拦截效能,降低试验成本,研究了针对于远程空间目标的空间拦截器半实物仿真技术,构建了半实物系统。系统将拦截器内部的动能拦截器(大气层外)导引头实物置于仿真回路,真实模拟了二维导引头探... 详细信息

为了精确地评估空间拦截器拦截空间远程目标的拦截效能,降低试验成本,研究了针对于远程空间目标的空间拦截器半实物仿真技术,构建了半实物系统。系统将拦截器内部的动能拦截器(大气层外)导引头实物置于仿真回路,真实模拟了二维导引头探测和跟踪目标过程。采用该系统对远程空间目标进行拦截仿真,结果表明,上述系统实现了对空间拦截系统的细粒度实时仿真,再现了其拦截过程,为拦截远程空中目标论证和性能评估提供数据支撑。

关键词：空间拦截器远程空间目标半实物

Enhancing sulfur cathode process via a functionalized complex molecule

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Nano Research 2023年第6期16卷 8385-8393页

作者： qingyi zheng Xiaoxiang fan Guoqing Liu qing Hou Jingmin fan Mingsen zheng Quanfeng Dong Department of Chemistry College of Chemistry and Chemical EngineeringCollaborative Innovation Centre of Chemistry for Energy Materials(iChEM)and State Key Laboratory of Physical Chemistry of Solid SurfacesXiamen UniversityXiamen 361005China

Lithium-sulfur batteries are regarded as promising next-generation energy storage batteries for their ultra-high theoretical energy ***,the complex sulfur electrode process with sluggish sulfur conversion reactions is a critical issue for lithiumsulfur batteries,in which catalytic interfacial reactions and accelerated lithium-ion diffusion are the key *** previous work has shown that implanting functional molecules with multiple redox properties in the electrode can break through the conventional diffusion layer constraints and achieve forced *** this work,a functionalized complex molecule,methylene blue anthraquinone-2-sulfonate(MB-AQ),with multiple redox activities as well as abundant active sites,was synthesized and introduced into the sulfur *** addition to accelerating the transport of lithium ions by reversible inhaling and exhaling lithium ions,the MB-AQ can combine polysulfides by its active sites to accelerate sulfur conversion *** from two functions of accelerating ion diffusion and catalyzing interfacial reactions,MB-AQ/reduced graphene oxide(rGO)/S cathode can achieve high initial capacities of 884 and 674 mAh·g^(−1)with stable cycling of 700 and 1,000 times at 1 and 4 C,*** is worth mentioning that the capacity of 462 mAh·g^(−1)can be achieved even at a high current density of 6 *** work provides a new approach to enhancing the sulfur cathode process.

关键词： lithium-sulfur batteries organic molecule dual-function sulfur conversion shuttle effect

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碳酸盐岩储集层定量评价——以塔河油田为例

新疆石油地质 2003年第2期24卷 146-148页

作者：张诗青樊政军柳建华高秋涛刘杰新疆石油管理局测井公司新疆克拉玛依834000 中石化新星石油公司西北石油局测井站新疆乌鲁木齐830011

塔河油田奥陶系碳酸盐岩是一套低孔、低渗缝洞型、非均质性强、流体性质多样化的复杂储集层,断层多、构造形态复杂。对于裂缝性储集层,电成像资料可以很直观、形象地反映裂缝的倾向、倾角,孔洞和溶蚀洞的发育程度,是目前最先进和最优越... 详细信息

塔河油田奥陶系碳酸盐岩是一套低孔、低渗缝洞型、非均质性强、流体性质多样化的复杂储集层,断层多、构造形态复杂。对于裂缝性储集层,电成像资料可以很直观、形象地反映裂缝的倾向、倾角,孔洞和溶蚀洞的发育程度,是目前最先进和最优越的适于裂缝地层的测井技术。另外,双侧向幅度差异在一定程度上也能反映裂缝的特征。因而,可综合利用常规、电成像资料、多极子声波XMAC等资料识别孔、洞、缝储集层。在结合生产实际的基础上,提出了利用“权重”评价法对塔河油田奥陶系储集层进行分类定量评价研究,经试油验证,符合率达92.3%.在此基础上,又对奥陶系I类储集层发育厚度进行了横向展布预测,结果表明,符合塔河油田的地区规律,应用效果很好。

关键词：塔河油田碳酸盐岩储集层测井技术裂缝地层定量评价 “权重”评价法横向预测电成像

Discordance between family report and clinical assessment of suicide attempts: a prospective study from the emergency department

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General Psychiatry 2021年第6期34卷 24-33,I0007页

作者： Yue zheng Haiyin Zhang qing fan East China University of Science and Technology ShanghaiChina Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineShanghaiChina Shanghai Key Laboratory of Psychotic Disorders ShanghaiChina

background Developing accurate identification methods for individuals with suicide attempts and providing them with follow-up care and supports can be a vital component of all comprehensive suicide prevention ***,because of the difficulties concerning one’s intentions behind injurious behaviour,identifying suicide attempts is a challenge for families and *** The aim of this study was to investigate the differences between family report and clinical assessment for suicide attempts in the emergency department(ED).Methods A total of 148 patients with suspected suicide attempts(SSAs)and 148 family caregivers in the ED were *** suicide risk module of the Chinese version of the MINI International Neuropsychiatric Interview and the self-report measure were used to assess those with SSA’s suicidal *** Family Adaptability and Cohesion Evaluation Scales and semi-structured interviews were used to investigate the characteristics of suicide risk and demographics of patients with SSA,as well as the rate and influencing factors of omitted suicide attempts reported by family *** The underreporting rate for family reported suicide attempts in the ED was 69.0%.The suicide attempts group indicated lower mean scores on perceptions of family resources,adaptability and ***'suicide risk rating(OR=0.152,95%CI:0.037 to 0.620,p=0.009),adult-children relationship(OR=5.037,95%CI:1.478 to 17.167,p=0.010)and caregiver’s age(OR=0.279,95%CI:0.103 to 0.757,p=0.012)might be associated with underreporting by *** patients committed suicide attempts through a falling injury or medication overdose,their families may have misreported the suicide *** The discordance of suicide attempt records between family report and clinical assessment reveals the limitations of family self-reports when identifying suicide *** and observations,together with information from certain diagnoses,should be com

关键词： prevention department assessment

Joint regression and learning from pairwise rankings for personalized image aesthetic assessment

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Computational Visual Media 2021年第2期7卷 241-252页

作者： Jin Zhou qing Zhang Jian-Hao fan Wei Sun Wei-Shi zheng School of Electronics and Information Technology Sun Yat-sen UniversityGuangzhou 510006China. School of Computer Science and Engineering Sun Yat-sen UniversityGuangzhou 510006China Key Laboratory of Machine Intelligence and Advanced Computing Ministry of Education(Sun Yat-sen University)Guangzhou 510006China Peng Cheng Laboratory Shenzhen 518000China

Recent image aesthetic assessment methods have achieved remarkable progress due to the emergence of deep convolutional neural networks(CNNs).However,these methods focus primarily on predicting generally perceived preference of an image,making them usually have limited practicability,since each user may have completely different preferences for the same *** address this problem,this paper presents a novel approach for predicting personalized image aesthetics that fit an individual user’s personal *** achieve this in a coarse to fine manner,by joint regression and learning from pairwise ***,we first collect a small subset of personal images from a user and invite him/her to rank the preference of some randomly sampled image *** then search for the K-nearest neighbors of the personal images within a large-scale dataset labeled with average human aesthetic scores,and use these images as well as the associated scores to train a generic aesthetic assessment model by CNN-based ***,we fine-tune the generic model to accommodate the personal preference by training over the rankings with a pairwise hinge *** demonstrate that our method can effectively learn personalized image aesthetic preferences,clearly outperforming state-of-the-art ***,we show that the learned personalized image aesthetic benefits a wide variety of applications.

关键词： s personalized image aesthetic assessment deep convolutional neural networks pairwise ranking regression

基于IWOA-LSTM算法的预应力钢筋混凝土梁损伤识别

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江苏大学学报（自然科学版） 2025年第1期46卷 105-112,119页

作者：范旭红章立栋杨帆李青郁董凯江苏大学土木工程与力学学院江苏镇江212013 河南省公路工程局集团第二公路工程有限公司河南郑州450015 中国葛洲坝集团第二工程有限公司四川成都610091

为准确识别桥梁结构的损伤程度,制作了桥梁的关键构件——预应力钢筋混凝土梁,进行三点弯曲加载试验.收集了损伤破坏全过程的声发射(AE)信号,通过AE信号参数分析,将梁的损伤破坏过程划分为4个典型阶段.构建了长短时记忆神经网络(LSTM)模... 详细信息

为准确识别桥梁结构的损伤程度,制作了桥梁的关键构件——预应力钢筋混凝土梁,进行三点弯曲加载试验.收集了损伤破坏全过程的声发射(AE)信号,通过AE信号参数分析,将梁的损伤破坏过程划分为4个典型阶段.构建了长短时记忆神经网络(LSTM)模型,根据经验设置LSTM模型的超参数容易导致网络陷入局部最优而影响了分类结果,提出采用Sine混沌映射和自适应权重来改进鲸鱼优化算法(WOA),对LSTM进行超参数寻优.设计了IWOA-LSTM算法模型,训练识别试验梁各损伤阶段的AE信号特征参数.定型网络结构,并识别同种工况下其他梁的AE信号.结果表明:IWOA-LSTM算法模型识别准确率均超过或接近92%,相较于普通LSTM模型,IWOA-LSTM模型识别准确率提高了约7%.

关键词：预应力钢筋混凝土梁声发射损伤识别长短时记忆神经网络改进的鲸鱼优化算法

A new method for computing the uniaxial modulus of articular cartilages using modified inhomogeneous triphasic model

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Acta Mechanica Sinica 2010年第1期26卷 121-126页

作者： Haijun Niu qing Wang Yongping zheng Yubo fan Department of Biomedical Engineering Beihang University 100191 Beijing China HT1 The Hong Kong Polytechnic University00852 Hong Kong China

It is well known that subtle changes in structure and tissue composition of articular cartilage can lead to its degeneration. The present paper puts forward a modified layered inhomogeneous triphasic model with four parameters based on the inhomogeneous triphasic model proposed by Narmoneva et al. Incorporating a piecewise fitting optimization criterion, the new model was used to obtain the uniaxial modulus Ha, and predict swelling pattern for the articular cartilage based on ultrasound-measured swelling strain data. The results show that the new method can be used to provide more accurate estimation on the uniaxial modulus than the inhomogeneous triphasic model with three parameters and the homogeneous mode, and predict effectively the swell- ing strains of highly nonuniform distribution of degenerated articular cartilages. This study can provide supplementary information for exploring mechanical and material properties of the cartilage, and thus be helpful for the diagnosis of osteoarthritis-related diseases.

关键词： Articular cartilage Triphasic model Inhomogeneous Osmotic pressure Unaxial module

Design and performance study of a dielectric-filled cavity beam current monitor for HUST-PTF

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Nuclear Science and Techniques 2023年第8期34卷 75-85页

作者： Ji-qing Li Kuan-Jun fan zheng-zheng Liu Jian Wang Qu-Shan Chen Jin-Feng Yang State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074China The Institute of Scientific and Industrial Research Osaka University8-1 MihogaokaIbarakiOsaka 567-0047Japan

To guarantee the exact proton dose applied to patients and ensure treatment safety while disrupting and destroying tumor cells,it is essential to accurately monitor the proton beam current in real time during patient *** clinical treatment requires a proton beam current in the∼nA range,nondestructive beam current monitors(BCMs)are preferred to minimize the degradation of beam ***,this poses significant challenges in accurately monitoring such extremely low beam *** study proposes a cavity-type BCM equipped with a dielectric plate to reduce its dimensions and achieve sufficient measurement sensitivity for practical requirements.A prototype cavity BCM was fabricated,and off-line testing was performed using a metal wire to simulate the beam to study its *** the simulation and experi-mental results showed that the cavity BCM could measure ultralow proton beam currents with a resolution up to 0.03 nA.

关键词： Proton therapy Beam current Cavity BCM Nondestructive