检索结果-南通市图书馆

Dynamic Data Updating Algorithm for Image Superresolution Reconstruction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geo-Spatial Information Science 2006年第3期9卷 196-200页

作者： TAN Bing XU qing zhang yan XING Shuai Jiangnan Remote Sensing and Application Research Center 158 Shaoniancun RoadShanghai 200436China.

A dynamic data updating algorithm for image superesolution is proposed. On the basis of Delaunay triangulation and its local updating property, this algorithm can update the changed region directly under the circumstances that only a part of the source images has been changed. For its high efficiency and adaptability, this algorithm can serve as a fast algorithm for image superesolution reconstruction.

关键词： image superresolution image interpolation image registration Delaunay triangulation

Space-occupying lesions of the lacrimal gland at one tertiary eye center in China: a retrospective clinical study of 95 patients

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2012年第2期5卷 208-211页

作者： Xiang-Ning Wang Jiang Qian Yi-Fei Yuan Rui zhang and yan-qing zhang Department of Ophthalmology Eye and ENT Hospital of Fudan University Shanghai 200031 China

AIM: To investigate the treatment status and prognosis of space-occupying lacrimal gland lesions at one tertiary eye center in China. METHODS: A retrospective clinical study was performed on 95 patients with space-occupying lesions of the lacrimal gland surgically treated at the Eye & ENT Hospital of Fudan University from 2003 to 2007. The reviewed clinical data included age, gender, side of the lesion, duration of signs and symptoms, histopathological diagnosis, treatment modality, recurrence (local, regional, and distant metastasis) and survival. RESULTS: Of the 95 cases (99 eyes), pleomorphic adenomas were the most common lesions (43 cases), followed by lymphoid disorders (14), inflammatory pseudotumors (11), carcinoma ex-pleomorphic adenomas (11), and adenoid cystic carcinomas (ACC, 6). There were 8 patients with relapsed pleomorphic adenomas. Five of these 8 cases had malignant pathological changes. All patients with ACC had metastasis and three of them died during their follow-up. CONCLUSION: Our study indicated that the most common lacrimal gland lesions were pleomorphic adenomas. Multiple recurrence and surgical procedures may increase the risk of tumor progression. ACC had a high incidence of tumor metastasis and a poor prognosis.

关键词： lacrimal gland lesions pleomorphic adenomas adenoid cystic carcinoma China

Prokaryotic Expression of Gly-Gln Dipeptide and Its Bioactive Analysis: A Novel Method for Short Peptide Production

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2010年第5期9卷 736-744页

作者： XU Ping-wen FANG Xin-ling SHU Gang ZHU Xiao-tong LUO Zeng-fu JIANG qing-yan GAO Ping zhang Yong-liang College of Animal Science South China Agricultural University Guangzhou 510642 P.R.China

Small bioactive peptides, with diverse biological functions, have received increasing attention as physiologically beneficial substances in animal production. The main obstacle to wide application of small bioactive peptides is a lack of costeffective methods for mass production. In this study, we mass-production method for small bioactive peptides. used glycyl-glutamine （Gly-Gln） as a test case to develop a novel The oligonucleotide encoding Gly-Gln pro-peptide （Gpp） was designed and synthesized. Gpp includes 3 Gly-Gln dipeptides and 2 enzymatic sites for pepsin and trypase, allowing direct digestion and absorption of Gly-Gln in the gastrointestinal tract. The Gpp oligonucleotides were linked to generate an oligomeric oligonucleotide segment containing 12 tandem copies of Gpp. This 12Gpp segment was cloned and expressed in Escherichia coli vector pET32a. By optimizing culture conditions [0.1 mmol L^-1 isopropyl-β-D- thiogalactopyranoside （IPTG）, 50 μg mL^-1 ampicillin （Amp）, 30℃ for 12 h], the thioredoxin fusion peptides reached 40% of total bacterial protein. After purification, the fusion protein was fed to Kunming mice to determine its effect on mouse immune function. The results showed that similar to Gly-Gln dipeptide, Gpp polymer protein could significantly suppress the proliferation of T and B lymphocytes in blood and spleen, and additionally could significantly improve interleukin-2 （IL-2） and interleukin-6 （IL-6） secretion of blood and spleen lymphocytes. These effects were not observed in mice fed a 2 amino acids mix （glycine and glutamine）. These evidences indicated that an efficient digestion of Gpp polymer protein could be achieved when ingested into the animal gut. The expression system in this study provides a potential production method for not only Gly-Gln dipeptide but also other short bioactive peptides.

关键词： glycyl-glutamine tandem expression gastrointestinal tract

Upregulation of MiR-126 Delays the Senescence of Human Glomerular Mesangial Cells Induced by High Glucose via Telomere-p53-p21-Rb Signaling Pathway

在线全文

学校读者我要写书评

暂无评论

Current Medical Science 2018年第5期38卷 758-764页

作者： Dong-wei CAO Chun-ming JIANG Cheng WAN Miao ZHANC qing-yan zhang Min ZHAO Bo yanG Da-long ZHU Xiao HAN Department of Nephrology Nanjing Drum Tower HospitalClinical College of Nanjing Medical UniversityNanjing 210008China Department of Nephrology Nanjing Drum Tower Hospitalthe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210008China Department of Dermatology Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China Department of Endocrinology Nanjing Drum Tower HospitalClinical College of Nanjing Medical UniversityNanjing 210008China Basic Medical School Naniing Medical UniversityNanjing 210000China

Diabetic kidney disease (DKD)is a microvascular complication of type 2 *** study of DKD mechanisms is the most important target for the prevention of *** senescence is one of the important pathogeneses for DKD,but the mechanism of renal and cellular senescence is *** expression of circulating miR-126 is associated with the development of DKD and may be a promising blood-based biomarker for *** study is to probe the effect and mechanism of miR-126 on the aging of human glomerular mesangial cells (HGMCs)induced by high *** were cultured with Roswell Park Memorial Institute (RPMI-1640)in *** effect of high glucose on morphology of HGMCs was observed 72h after *** cell cycle was examined by flow *** telomere length was measured by Southern *** expression levels of p53,p21 and Rb proteins in p53-p21-Rb signaling pathway and p-statl,p-stat3 in JAK/STAT signaling pathway were detected by Western blotting *** expression of miR-126 was examined by ***-126 mimics was transfected into *** effects of miR-126 mimics transfection on cell morphology,cell cycle,telomere length,p53,p21,Rb,p-stat1 and p-stat3 were observed. The results showed that high glucose not only arrested the cell cycle in G1phase but also shortened the telomere *** glucose led to high expression of p53,p21,Rb,p-statl and p-stat3 and premature senescence of HGMCs by activating the telomere-p53-p21-Rb and JAK/STAT signaling ***,the miR-126 was decreased in HGMCs induced by high *** was suggested that the transfection of miR-126 mimics could inhibit the telomere-p53-p21-Rb and JAK/STAT signaling pathway activity in vitro and delay the senescence of *** results may serve as a new strategy for the treatment of DKD.

关键词： diabetic kidney disease miR-126 human glomerular mesangial cells senescence telomere-p53-p21-Rb signaling pathway

Global Warming Impacts on Alpine Vegetation Dynamic in qinghai-Tibet Plateau of China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geoscience and Environment Protection 2014年第3期2卷 54-59页

作者： yan qing zhang Jeffery M. Welker Department of Geography School of Computing Science Simon Fraser University Burnaby Canada Environment and Natural Resources Institute University of Alaska Anchorage Anchorage USA

This study is to illustrate alpine vegetation dynamics in qinghai-Tibetan Plateau of China from simulated filed experimental climate change, vegetation community dynamic simulation integrated with scenarios of global temperature increase of 1 to 3°C, and simulated regional alpine vegetation distribution changes in responses to global warming. Our warming treatment increased air temperatures by 5°C on average and soil temperatures were elevated by 3°C at 5 cm depth. Above- ground biomass of grasses responded rapidly to the warmer conditions whereby biomass was 25% greater than that of controls after only 5 wk of experimental warming. This increase was accompanied by a simultaneous decrease in forb biomass, resulting in almost no net change in community biomass after 5 wk. Under warmed conditions, peak community bio-mass was extended into October due in part to continued growth of grasses and the postponement of senescence. The Vegetation Dynamic Simulation Model calculates a probability surface for each vegetation type, and then combines all vegetation types into a composite map, determined by the maximum likelihood that each vegetation type should distribute to each raster unit. With scenarios of global temperature increase of 1°C to 3°C, the vegetation types such as Dry Kobresia Meadow and Dry Potentilla Shrub that are adapted to warm and dry conditions tend to become more dominant in the study area.

关键词： Global Warming Alpine Vegetaion qinghai-Tibet Plateau

Correlation between Histone Deacetylase 9 and Regulatory T Cell in Patients with Chronic Heart Failure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Medical Science 2018年第2期38卷 199-203页

作者： Ping-ping LIAO Li-hua LIU Bin WANG Xin FANG Shao-qiong ZHOU Wei LI yan-qing zhang Si-ming GUAN Department of Geriatrics the Affiliated Hospital of Qingdao University Qingdao 266003 China Department of Geriatrics Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

Heart failure （HF） is the end stage of various kinds of cardiovascular diseases and leads to a high mortality worldwide. Numerous studies have demonstrated that frequencies of CD4＋CD25＋Foxp3＋ regulatory T cells （Tregs） are reduced in HF patients and properly expanding Tregs attenuates HF progression. Histone deacetylase （HDAC） 9 has been revealed to contribute to several cardiovascular and cerebrovascular diseases. Plenty of studies showed that HDAC9 negatively regulated the number and function of Tregs. Thus, we aim to investigate the expression of HDAC 9 in patients with chronic heart failure （CHF） and the relationship among HDAC9, Tregs and CHF. Our research showed a reduced number of Tregs and an increased expression of HDAC9 mRNA in CHF patients. Patients with CHF were divided into two groups by heart function grade of New York Heart Association （NYHA）, we found that the HDAC9 mRNA expression level in NYHA grade Ⅱ -Ⅲ group were lower than that in NYHA grade IV group. More importantly, the correlation study suggested that the expression of HDAC9 mRNA was negatively correlated to Tregs frequency and left ventricular ejection fraction （LVEF）, whereas positively correlated to larger left ventricular end-diastolic dimension （LVEDD） and B-type natriuretic peptide （BNP） in patients with CHF. The correlation studies also showed a positive correlation between HDAC9 and the severity of CHF. Our research suggests that HDAC9 may be a new indicator for assessing CHF and it may offer a new direction for research of CHF.

关键词： histone deacetylase 9 heart failure regulatory T cells B-type natriuretic peptide

Microstructures and mechanical properties of AZ91D/0Cr19Ni9 bimetal composite prepared by liquid-solid compound casting

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2019年第1期29卷 51-58页

作者： Jian-hua ZHAO Wen-qun ZHAO Shen QU yan-qing zhang State Key Laboratory of Mechanical Transmission Chongqing University Chongqing 400044 China College of Materials Science and Engineering Chongqing University Chongqing 400044 China

The liquid-solid compound casting technology was used to produce the AZ91D/0Cr19Ni9 bimetal composite without and with hot dipping aluminium, respectively. The influences of Al coating on microstructures and mechanical properties of AZ91D/0Cr19Ni9 interface were investigated. The results showed that the mechanical bonding was obtained between AZ91D and bare steel 0Cr19Ni9 where a gap existed at the interface; the metallurgical bonding was formed between AZ91D and Al-coated 0Cr19Ni9, which could be divided into two different intermetallic layers: layer Ⅰ was mainly composed of α-Mg+β-Mg17Al12 eutectic structure and a small amount of MgAl2O4, and layer Ⅱ mainly comprised of Fe2Al5 intermetallic compound. Furthermore, the hardness value of interface was obviously higher than that of AZ91D matrix, and the average hardness values of layers Ⅰ and Ⅱ were HV 158 and HV 493, respectively. The shear strength of AZ91D/Al-coated 0Cr19Ni9 interface was higher than that of AZ91D/bare 0Cr19Ni9 interface, which confirmed that Al coating could improve the adhesive strength between AZ91D and 0Cr19Ni9 during liquid-solid compound casting process.

关键词： AZ91D 0Cr19Ni9 liquid-solid compound casting interface bonding shear strength

Application of data warehouse in power transformer diagnosis system

在线全文

学校读者我要写书评

暂无评论

通讯和计算机（中英文版） 2009年第11期6卷 17-20页

作者： ZHAO Wen-qing zhang yan-fang WANG Xiao-hui School of Computer Science and Technology North China Electric Power University Baoding 071003 China

产品伤害危机下搜索引擎用户持续使用行为影响因素分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

情报科学 2017年第2期35卷 63-68页

作者：张敏唐国庆张艳武汉大学信息管理学院湖北武汉430072 中国科学院大学公共政策与管理学院北京100049

【目的/意义】为探究产品伤害危机情境下搜索引擎用户的持续使用行为的影响因素及其内在作用机理。【方法/过程】在整合信息系统持续使用的期望确认理论、感知风险理论、归因理论、计划行为理论和习惯理论的基础上,提出研究假设并构建... 详细信息

【目的/意义】为探究产品伤害危机情境下搜索引擎用户的持续使用行为的影响因素及其内在作用机理。【方法/过程】在整合信息系统持续使用的期望确认理论、感知风险理论、归因理论、计划行为理论和习惯理论的基础上,提出研究假设并构建了理论模型,同时进行了实证研究。【结果/结论】研究结果显示,期望确认正向刺激搜索引擎用户的感知有用性和使用满意度,感知有用性能促进使用满意度,使用满意度能促进持续使用意愿;责任归因对感知使用风险具有促进作用,感知使用风险对使用满意度和持续使用意愿均具有抑制作用;持续使用态度正向影响持续使用意愿,持续使用意愿和使用习惯均正向影响持续使用行为。

关键词：产品伤害危机搜索引擎持续使用