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Research on the prognostic value of adjusting intraperitoneal threedimensional quality evaluation mode in laparoscopic cholecystectomy patients

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1078-1086页

作者： Yuan Zhou zhan.qing Chen Operating Room Lianyungang Hospital of Traditional Chinese MedicineLianyungang 222000Jiangsu ProvinceChina Operating Room The Second People's Hospital of Lianyungang Affiliated to Kangda College of Nanjing Medical UniversityLianyungang 222000Jiangsu ProvinceChina

BACKGROUND Benign gallbladder diseases have become a high-prevalence condition not only in China but also *** main types of benign gallbladder diseases include gallbladder polyps,acute and chronic cholecystitis,and gallstones,with gallstones being the most common,accounting for over 70%of *** the mortality rate of benign gallbladder diseases is low,they carry obvious potential *** have shown that an increased incidence of benign gallbladder diseases can increase the risk of cardiovascular diseases and gallbladder cancer,resulting in a substantial disease burden on patients and their *** To assess the medical utility of the Configuration-Procedure-Consequence(CPC)three-dimensional quality evaluation model in modulating the prognosis of laparoscopic cholecystectomy *** A total of 98 patients who underwent laparoscopic cholecystectomy in our hospital from February 2020 to January 2022 were selected as the *** to the random number table method,they were divided into a study group and a control group,with 49 patients in each *** control group received routine perioperative care,while the study group had the addition of the CPC three-dimensional quality *** postoperative recovery-related indicators(time to first flatus,time to oral intake,time to ambulation,hospital stay),stress indicators(cortisol and adrenaline levels),distinctions in anxiety and RESULTS The time to first flatus,time to oral intake,time to ambulation,and hospital stay of the study group patients were obviously lower than those of the control group patients,with statistical significance(P0.05).However,on the 3rd day after surgery,the cortisol and adrenaline leve

关键词： Configuration-Procedure-Consequence Three-dimensional quality evaluation Laparoscopic Cholecystectomy Recovery process Anxiety and depression Complications

Selective extinction and habitat nestedness are the main drivers of lizard nestedness in the Zhoushan Archipelago

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Current Zoology 2024年第2期70卷 244-252页

作者： Minchu zhan. Chaonan Tang qing zhan. Chengxiu zhan.Chuanwu Chen Yanping Wang Laboratory of Island Biogeography and Conservation Biology College of Life SciencesNanjing Normal UniversityNanjing 210023China

Nested subset pattern(nestedness)is an important part of the theoretical framework of island biogeography and community ***,most previous studies often used nestedness metrics or randomization algorithms that are vulnerable to type I *** this study,we inves-tigated the nestedness of lizard assemblages on 37 islands in the Zhoushan Archipelago,*** used the line-transect method to survey species occurrence,abundance,and habitat types of lizards on 37 islands during 2 breeding seasons in 2021 and *** applied the nested metric WNODF and the conservative rc null model to control for type I error and quantify the significance of *** rank cor relations were used to evaluate the role of 4 habitat variables(island area,2 isolation indices,and habitat diversity)and 4 ecological traits(body size,geographic range size,clutch size,and minimum area requirement)in generating *** results of WNODF analyses showed that lizard assemblages were significantly *** habitat-by-site matrix estimated by the program NODF was also significantly nested,support-ing the habitat nestedness *** nestedness of lizard assemblages were significantly correlated with island area,habitat *** size,and minimum area ***,our results suggest that selective extinction and habitat nestedness were the main drivers of lizard nestedness in our *** contrast,the nestedness of lizard assemblages was not due to passive sampling or selective *** maximize the number of species preserved,our results indicate that we should protect both large islands with diverse habitats and species with largearea requirement and clutch size.

关键词： clutch size habitat nestedness lizards minimum area requirement nestedness selective extinction WNODF Zhoushan Archipelago.

Optimizing near-carbon-free nuclear energy systems:advances in reactor operation digital twin through hybrid machine learning algorithms for parameter identification and state estimation

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Nuclear Science and Techniques 2024年第8期35卷 177-203页

作者： Li‑zhan.Hong He‑Lin Gong Hong‑Jun Ji Jia‑Liang Lu Han Li qing Li Paris Elite Institute of Technology Shanghai Jiao Tong UniversityShanghai 200240China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of ChinaChengdu 610041China

Accurate and efficient online parameter identification and state estimation are crucial for leveraging digital twin simulations to optimize the operation of near-carbon-free nuclear energy *** previous studies,we developed a reactor operation digital twin(RODT).However,non-differentiabilities and discontinuities arise when employing machine learning-based surrogate forward models,challenging traditional gradient-based inverse methods and their *** study investigated deterministic and metaheuristic algorithms and developed hybrid algorithms to address these *** efficient modular RODT software framework that incorporates these methods into its post-evaluation module is presented for comprehensive *** methods were rigorously assessed based on convergence profiles,stability with respect to noise,and computational *** numerical results show that the hybrid KNNLHS algorithm excels in real-time online applications,balancing accuracy and efficiency with a prediction error rate of only 1%and processing times of less than 0.1 ***,algorithms such as FSA,DE,and ADE,although slightly slower(approximately 1 s),demonstrated higher accuracy with a 0.3%relative L_2 error,which advances RODT methodologies to harness machine learning and system modeling for improved reactor monitoring,systematic diagnosis of off-normal events,and lifetime management *** developed modular software and novel optimization methods presented offer pathways to realize the full potential of RODT for transforming energy engineering practices.

关键词： Parameter identification State estimation Reactor operation digital twin Reduced order model Inverse problem

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Sand control mechanism of radial well filled with phase change material in hydrate reservoir

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Petroleum Science 2024年第4期21卷 2571-2582页

作者： Xiao-Qiang Liu Zhong-Xi Han Zhi-Lin Luo Hai-Long Lu Ying Sun qing You Tian-Kui Guo zhan.qing Qu School of Energy Resources China University of Geosciences (Beijing) Beijing Key Laboratory of Unconventional Natural Gas Geological Evaluation and Development Engineering China University of Geosciences (Beijing) China Research Institute of Petroleum Exploration and Development Engineering Technology Research Institute of Southwest Oil & Gas Field Company PetroChina Beijing International Center for Gas Hydrate School of Earth and Space Sciences Peking University School of Advanced Material Peking University Shenzhen Graduate School School of Petroleum Engineering China University of Petroleum (East China)

Radial well filled with phase change material has been proposed as a novel sand control method for hydrate exploitation. In order to reveal the sand control mechanism, CFD-DEM coupling method is applied to simulate the migration, settlement, and blockage processes of sand particles in the radial *** obtained results indicate that three scenarios have been recognized for sand particles passing through sand control medium, based on the diameter ratio of sand control medium to sand particle（Dd）:fully passing（Dd= 8.75-22.5）, partially passing and partially blocked（Dd= 3.18-5.63）, and completely blocked（Dd= 2.18-3.21）. After being captured by the sand control medium, sand particles can block pores, which increases fluid flow resistance and causes a certain pressure difference in the radial *** pressure in the radial well should be lower than the hydrate phase equilibrium pressure during sand control design, for the purpose of promoting hydrate decomposition, and sand capture. The length of the radial well should be optimized based on the reservoir pore pressure, production pressure difference,bottom hole pressure, and the pressure gradient in the radial well. It should be noticed that the sand control medium leads to a decrease in permeability after sand particles captured. Even the permeability is reduced to several hundred millidarcy, it is still sufficient to ensure the effective flow of gas and water after hydrate decomposition. Increasing fluid velocity reduces the blocking capacity of the sand control medium, mainly because of deterioration in bridging between sand particles.

关键词： Hydrate reservoir Sand control Radial well CFD-DEM

Modeling and Analysis of Risk Propagation and Loss Causing Capacity for Key Nodes in Cyber-Physical Coupled Power Network

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Complex System Modeling and Simulation 2024年第2期4卷 124-136页

作者： Dongqi Liu Qiong zhan. Haolan Liang Tao zhan.rui Wang National Key Laboratory of Disaster Prevention and Reduction for Power Grid Changsha University of Science and TechnologyChangsha 410114China the School of Electrical and Information Engineering Changsha University of Science and TechnologyChangsha 410114China the College of Electrical and Information Engineering Hunan Institute of EngineeringXiangtan 411104China the School of Systems Engineering National University of Defense TechnologyChangsha 410003China

The modern power system has evolved into a cyber-physical system with deep coupling of physical and information domains,which brings new security *** at the problem that the“information-physical”cross-domain attacks with key nodes as springboards seriously threaten the safe and stable operation of power grids,a risk propagation model considering key nodes of power communication coupling networks is proposed to study the risk propagation characteristics of malicious attacks on key nodes and the impact on the ***,combined with the complex network theory,a topological model of the power communication coupling network is established,and the key nodes of the coupling network are screened out by Technique for Order Preference by Similarity to Ideal Solution(TOPSIS)method under the comprehensive evaluation index based on topological characteristics and physical ***,a risk propagation model is established for malicious attacks on key nodes to study its propagation characteristics and analyze the state changes of each node in the coupled ***,two loss-causing factors:the minimum load loss ratio and transmission delay factor are constructed to quantify the impact of risk propagation on the coupled ***,simulation analysis based on the IEEE 39-node system shows that the probability of node being breached(α)and the security tolerance of the system(β)are the key factors affecting the risk propagation characteristics of the coupled network,as well as the criticality of the node is positively correlated with the damage-causing *** proposed methodological model can provide an effective exploration of the diffusion of security risks in control systems on a macro level.

关键词： cyber-physical system risk propagation complex network loss causative factor

Design parameter optimization method for a prestressed steel structure driven by multi-factor coupling

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1066-1083页

作者： Guo-Liang SHI zhan.Sheng LIU De-Chun LU qing-Wen zhan. Majid DEZHKAM Ze-Qiang WANG Faculty of Architecture Civil and Transportation EngineeringBeijing University of TechnologyBeijing 100124China The Key Laboratory of Urban Security and Disaster Engineering of the Ministry of Education Beijing University of TechnologyBeijing 100124China Beijing Building Construction Research Institute Co. Ltd.Beijing 100039China

To achieve efficient structural design,it is crucial to reduce the cost of materials while ensuring structural *** study proposes an optimization method for design parameters(DPs)in a prestressed steel structure driven by multi-factor *** accomplish this,a numerical proxy model of prestressed steel structures is established with integration of DPs and mechanical parameters(MPs).A data association-parameter analysis-optimization selection system is established.A correlation between DPs and MPs is established using a back propagation(BP)neural *** correlation provides samples for parameter analysis and optimization *** are used to characterize the safety of the *** on the safety grade analysis,the key DPs that affect the mechanical properties of the structure are obtained.A mapping function is created to match the MPs and the key *** optimal structural DPs are obtained by setting structural materials as the optimization objective and safety energy as the constraint *** theoretical model is applied to an 80-m-span gymnasium and verified with a scale test physical *** MPs obtained using the proposed method are in good agreement with the experimental *** with the traditional design method,the design cycle can be shortened by more than 90%.Driven by the optimal selection method,a saving of more than 20% can be achieved through reduction of structural material ***,the cross-sectional dimensions of radial cables have a substantial influence on vertical *** initial tension and cross-sectional size of the upper radial cable exhibit the most pronounced impact on the stress distribution in that *** initial tension and cross-sectional size of the lower radial cable hold the greatest sway over the stress distribution in that cable.

关键词： structure design association relationship performance analysis optimum selection experimental verification

Different responses of two adjacent artificial beaches to Typhoon Hato in Zhuhai,China

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Journal of Oceanology and Limnology 2024年第2期42卷 511-521页

作者： Jun ZHU qing WANG Chao zhan.Fengjuan SUN Wenhao HUA Jianhui LIU Hongshuai QI Yu YANG Coastal Research Institute Ludong UniversityYantai 264025China Third Institute of Oceanography Ministry of Natural ResourcesXiamen 261005China

Major differences in beach erosion between two neighboring artificial beaches Xiangluwan Beach(XL beach)and Meiliwan Beach(ML beach)in Zhuhai,China,were studied after Super Typhoon *** this study,a fully nonlinear Boussinesq wave model(FUNWAVE)-Total Variation Diminishing(TVD)was used to distinguish the main impact factors,their relative contributions,and the hydrodynamic mechanisms underlying the different beach *** show that compared to the ML beach,the main reason for the relatively weak erosion on Xiangluwan(XL)beach was the smaller beach berm height(accounting for approximately 75.9%of the erosion response).Regarding the beach with a higher berm,the stronger wave-induced undertow flow,along with the higher sediment concentration,led to a higher offshore sediment transport flux,resulting in more severe erosion relative to the beach with a smaller berm *** second most important reason explaining the weak erosion on XL beach was the absence of seawalls(accounting for approximately 17.9%of the erosion response).Wave reflection induced by the seawall could cause higher suspended sediment concentration,resulting in a toe scouring near the *** offshore submerged breakwater protected XL beach slightly(accounting for approximately 6.1%of the erosion response).Due to the higher water level induced by storm surge,most of the wave energy could penetrate through the submerged *** effect of the larger berm width of XL beach was *** to the beach with a larger berm width,the erosion/deposition regions in the beach with a narrower berm width showed shoreward migration,without significant changes in the erosion/deposition *** of this,the larger berm width could reduce the wave energy reaching the *** study of the storm stability of artificial beaches may be applied to beach restoration design.

关键词： beach erosion berm height berm width seawall fully nonlinear Boussinesq wave model(FUNWAVE)

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Integrative transcriptome analysis identifies MYBL2 as a poor prognosis marker for osteosarcoma and a pan-cancer marker of immune infiltration

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Genes & Diseases 2024年第3期11卷 351-367页

作者： Xinzhu Quiu Hongbo He Hao Zeng Xiaopeng Tongg Can zhan. Yupeng Liu zhan.Liao qing Liu Department of Orthopaedics Xiangya HospitalCentral South UniversityChangshaHunan 410008China National Clinical Research Center for Geriatric Disorders Xiangya HospitalChangshaHunan 410008China Department of Sports Medicine Research Center of Sports MedicineXiangya HospitalCentral South UniversityChangshaHunan 410008China

MYBL2(MYB proto-oncogene like 2)is an emerging prognostic marker for malignant tumors,and its potential role in osteosarcoma and its relationship with immune infiltration in pan-cancer is yet to be *** constructed a transcription factor activity profile of os-teosarcoma using the single-cell regulatory network inference algorithm based on single-cell RNA sequencing data obtained from the Gene Expression ***,we calcu-lated the extent of MYBL2 activation in malignant proliferative *** also explored the association between MYBL2 and chemotherapy resistance in ***,we systematically correlated MYBL2 with immunological signatures in the tumor microenviron-ment in pan-cancer,including immune cell infiltration,immune checkpoints,and tumor immu-notherapy ***,we developed and validated a risk score(MRGS),derived an osteosarcoma risk score nomogram based on MRGS,and tested its ability to predict ***2 and gene enrichment analyses in osteosarcoma and pan-cancer revealed that MYBL2 was positively correlated with cell proliferation and tumor immune ***2 expres-sion positively correlated with SLC19A1 in pan-cancer and osteosarcoma cell ***-cancer immune infiltration analysis revealed that MYBL2 was correlated with myeloid-derived sup-pressor cells,Th2 cell infiltration,CD276,RELT gene expression,and tumor mutation burden.

关键词： Biomarker Immunecheckpoint MYBL2 Osteosarcoma Pan-cancer

Fe-N-C heterogeneous Fenton-like catalyst for the degradation of tetracycline:Fe-N coordination and mechanism studies

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Chinese Chemical Letters 2024年第9期35卷 309-314页

作者： Weichen Zhu Wei Zuo Pu Wang Wei zhan.Jun zhan. Lipin Li Yu Tian Hong Qi rui Huang State Key Laboratory of Urban Water Resource and Environment(SKLUWRE) School of EnvironmentHarbin Institute of TechnologyHarbin 150090China Guangdong Yuehai Water Investment Co. Ltd.Shenzhen 518021China National Engineering Research Center of Urban Water Resources Co. Ltd.Harbin Institute of TechnologyHarbin 150090China

Fe-N-C materials have received increasing attention,due to its distinctive catalytic ***,the Fe-N coordination number dependence of catalytic ability and mechanism for H_(2)O_(2)activation remain ***,a series of Fe-N-C heterogeneous Fenton-like catalysts with different Fe-N coordination number were prepared for tetracycline *** results demonstrated that samples with Fe-N4 structure exhibited high *** excellent performance was mainly ascribed to the high adsorption capacity and the formation of superoxide radicals(•O_(2)^(−))catalyzed by Fe linked to pyridinic *** intermediates and degradation pathways of tetracycline degradation by Fe-N-C/H_(2)O_(2)system were analyzed by liquid chromatography coupled to tandem mass spectrometry(LC-MS/MS).Furthermore,we applied our Fe-N-C catalysts to treat simulated pharmaceutical wastewater with high tetracycline degradation capacity despite high concentrations of organic matter such as oxalic acid and various ionic *** work reveals the dependence of the activation H_(2)O_(2)on the Fe-N coordination environment and the degradation mechanism of these *** provides insights into the prospects for tuning the catalyst in practical applications.

关键词： H_(2)O_(2)activation Advanced oxidation process Superoxide radicals Degradation pathways EXAFS

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