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Repair of the portal vein using a hepatic ligamentum teres patch for laparoscopic pancreatoduodenectomy: A case report

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World Journal of Clinical Cases 2019年第18期7卷 2879-2887页

作者： Qiang Wei Qiang-Pu Chen qing-hai guan Wen-Tao Zhu Department of Hepatobiliary Surgery and Clinical Nutrition Center Binzhou Medical University Hospital

BACKGROUND Laparoscopic pancreatoduodenectomy (LPD) has been developed gradually with the advances in surgical laparoscopic techniques. It is technically challenging to perform LPD with portal vein resection and reconstruction. CASE SUMMARY A 71-year-old female patient was diagnosed with distal cholangiocarcinoma. After preoperative examination and rigorous preoperative preparation, the patient underwent LPD using 3D laparoscopy on July 17, 2018. During the surgery, we found that the tumor invaded the right wall of the portal vein;thus, pancreaticoduodenectomy combined with partial portal vein wall resection was performed. The defect of the portal vein wall was approximately 2.5 cm × 1.0 cm. The hepatic ligamentum teres was excised by laparoscopy and then recanalized in vitro. Following recanalization, the hepatic ligamentum teres was cut longitudinally and then trimmed into vascular patches that were then used to reconstruct the defect of the portal vein through 3D laparoscopy. The operative time was 560 min, and intraoperative blood loss was 100 mL. The duration of the blood occlusion time was 63 min. No blood transfusion was required. The patient underwent enhanced recovery after surgery procedures after the operation. The patient was discharged on postoperative day 11. Follow-up for 6 months after discharge showed no stenosis of the portal vein and good patency of blood flow. CONCLUSION It is safe and feasible to use the hepatic ligamentum teres patch to repair portal vein in LPD. However, the long-term patency of this technique for venous reconstruction requires further investigation.

关键词： Hepatic ligamentum teres patch Laparoscopic pancreatoduodenectomy Portal vein repair Case report

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Ligamentum teres hepatis as a graft for portal and/or superior mesenteric vein reconstruction:From bench to bedside

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World Journal of Gastrointestinal Surgery 2023年第4期15卷 674-686页

作者： Wen-Tao Zhu hai-Tao Wang qing-hai guan Fan Zhang Chang-Xi Zhang Feng-Ai Hu Bao-Lei Zhao Lei Zhou Qiang Wei hai-Bin Ji Ting-Liang Fu Xing-Yuan Zhang Rui-Tao Wang Qiang-Pu Chen Department of Hepatobiliary Surgery Binzhou Medical University HospitalBinzhou 256600Shandong ProvinceChina Department of Hepatobiliary Surgery Binzhou Medical University Affiliated Yantai HospitalYantai 264110Shandong ProvinceChina Department of Hepatobiliary Surgery and Clinical Nutrition Center Binzhou Medical University HospitalBinzhou 256600Shandong ProvinceChina Department of Clinical Medicine Laboratory Binzhou Medical University HospitalBinzhou 256600Shandong ProvinceChina Department of Pediatric Surgery Binzhou Medical University HospitalBinzhou 256600Shandong ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi'an 710061Shannxi ProvinceChina

BACKGROUND Pancreaticoduodenectomy combined with portal vein(PV)and/or superior mesenteric vein(SMV)resection in patients with pancreaticobiliary malignancy has become a common surgical *** are various grafts currently used for PV and/or SMV reconstruction,but each of these grafts have certain ***,it is necessary to explore novel grafts that have an extensive resource pool,are low cost with good clinical application,and are without immune response rejection or additional damage to *** To observe the anatomical and histological characteristics of the ligamentum teres hepatis(LTH)and evaluate PV/SMV reconstruction using an autologous LTH graft in pancreaticobiliary malignancy *** In 107 patients,the post-dilated length and diameter in resected LTH specimens were *** general structure of the LTH specimens was observed by hematoxylin and eosin(HE)*** fibers(CFs),elastic fibers(EFs),and smooth muscle(SM)were visualized by Verhoeff-Van Gieson staining,and the expression of CD34,factor VIII-related antigen(FVIIIAg),endothelial nitric oxide synthase(eNOS),and tissue type plasminogen activator(t-PA)were detected using immunohistochemistry in LTH and PV(control)endothelial *** and/or SMV reconstruction using the autologous LTH was conducted in 26 patients with pancreaticobiliary malignancies,and the outcomes were retrospectively *** The post-dilated length of LTH was 9.67±1.43 cm,and the diameter at a pressure of 30 cm H2O was 12.82±1.32 mm at the cranial end and 7.06±1.88 mm at the caudal *** cavities with smooth tunica intima covered by endothelial cells were found in HE-stained LTH *** relative amounts of EFs,CFs and SM in the LTH were similar to those in the PV[EF(%):11.23±3.40 vs 11.57±2.80,P=0.62;CF(%):33.51±7.71 vs 32.11±4.82,P=0.33;SM(%):15.61±5.26 vs 16.74±4.83,P=0.32].CD34,FVIIIAg,eNOS,and t-PA were expressed in both LTH and PV endothelial *** PV and

关键词： Ligamentum teres hepatis Pancreaticoduodenectomy Portal vein Superior mesenteric vein Vascular grafting Pancreaticobiliary malignancy

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Investigating the pharmacological basis and mechanisms of the anti-thrombotic effects of Paeoniae Radix Rubra， both pre- and post-stir-frying with rice wine

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Food Science and Human Wellness 2025年

作者： Jiaxu Zhang Jian guan Ajiao Hou Wenying Niu haixue Kuang Liu Yang hai Jiang Key Laboratory of Basic and Application Research of Beiyao， Heilongjiang University of Chinese Medicine， Ministry of Education

Paeoniae Radix Rubra (PRR) is a commonly used traditional Chinese medicine known for promoting blood circulation and alleviating pain. Stir-frying PRR with rice wine enhances its effectiveness in improving blood flow and resolving stasis. To explore the pharmacodynamic basis and mechanisms behind PRR's anti-thrombotic effects—both pre- and post-stir-frying—a comprehensive approach combining pharmacological research， metabolomics， and chemistry was employed. Fraction inter-cross validation experiments， pharmacological assessments， and metabolomic analyses confirm the efficacy of the fraction separation process. Wine-stir-fried PRR (WPRR) shows superior blood activation compared to PRR. PRR mainly affects the TCA cycle and sphingolipid metabolism pathways through its small molecules， enhancing coagulation and fibrinolysis systems' functionality. All the subdivided components of WPRR have anti-thrombotic effects， especially polysaccharides and oligosaccharides. WPRR improves thrombotic conditions in rat blood stasis by modulating arachidonic acid metabolism， TCA cycle， lipid status enhancement， and angiogenesis stimulation while regulating platelet adhesion and aggregation. In conclusion， compared with PRR， the main material basis for the blood-activating efficacy of WPRR has transformed from small molecule compounds to polysaccharide and oligosaccharide components. The action pathways of WPRR in exerting anti-thrombotic efficacy have increased. The polysaccharide components in WPRR might possess considerable potential for being developed into natural anti-thrombotic drugs.

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Well-posedness of two-phase local/nonlocal integral polar models for consistent axisymmetric bending of circular microplates

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Applied Mathematics and Mechanics(English Edition) 2022年第5期43卷 637-652页

作者： hai qing State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Previous studies have shown that Eringen’s differential nonlocal model would lead to the ill-posed mathematical formulation for axisymmetric bending of circular *** on the nonlocal integral models along the radial and circumferential directions,we propose nonlocal integral polar models in this *** proposed strainand stress-driven two-phase nonlocal integral polar models are applied to model the axisymmetric bending of circular *** governing differential equations and boundary conditions(BCs)as well as constitutive constraints are *** is found that the purely strain-driven nonlocal integral polar model turns to a traditional nonlocal differential polar model if the constitutive constraints are ***,the purely strain-and stress-driven nonlocal integral polar models are ill-posed,because the total number of the differential orders of the governing equations is less than that of the BCs plus constitutive *** nominal variables are introduced to simplify the mathematical expression,and the general differential quadrature method(GDQM)is applied to obtain the numerical *** results from the current models(CMs)are compared with the data in the *** is clearly established that the consistent softening and toughening effects can be obtained for the strain-and stress-driven local/nonlocal integral polar models,*** proposed two-phase local/nonlocal integral polar models(TPNIPMs)may provide an efficient method to design and optimize the plate-like structures for microelectro-mechanical systems.

关键词： softening effect toughening effect circular microplate nonlocal integral model general differential quadrature method(GDQM)

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Quantum dynamics of Gaudin magnets

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Communications in Theoretical Physics 2022年第9期74卷 39-48页

作者： Wen-Bin He Stefano Chesi hai-qing Lin Xi-Wen guan Beijing Computational Science Research Center Beijing 100193China State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsAPMChinese Academy of SciencesWuhan 430071China The Abdus Salam International Center for Theoretical Physics Strada Costiera 11I-34151 TriesteItaly Department of Physics Beijing Normal UniversityBeijing 100875China NSFC-SPTP Peng Huanwu Center for Fundamental Theory Xi’an 710127China Department of Theoretical Physics Research School of Physics and EngineeringAustralian National UniversityCanberra ACT 0200Australia

Quantum dynamics of many-body systems is a fascinating and significant subject for both theory and *** question of how an isolated many-body system evolves to its steady state after a sudden perturbation or quench still remains *** this paper,using the Bethe ansatz wave function,we study the quantum dynamics of an inhomogeneous Gaudin *** derive explicit analytical expressions for various local dynamic quantities with an arbitrary number of flipped bath spins,such as:the spin distribution function,the spin-spin correlation function,and the Loschmidt *** also numerically study the relaxation behavior of these dynamic properties,gaining considerable insight into coherence and entanglement between the central spin and the *** particular,we find that the spin-spin correlations relax to their steady value via a nearly logarithmic scaling,whereas the Loschmidt echo shows an exponential relaxation to its steady *** results advance the understanding of relaxation dynamics and quantum correlations of long-range interacting models of the Gaudin type.

关键词： Gaudin magnets central spin model Bethe ansatz spin polarization spin-spin correlation Loschmidt echo

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Finite Element Analysis of the Microstructure–Strength Relationships of Metal Matrix Composites

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Acta Metallurgica Sinica(English Letters) 2014年第5期27卷 844-852页

作者： hai qing State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and Astronautics

The influence of the shape and spatial distribution of reinforced particles on strength and damage of metal matrix composite （MMC） is investigated through finite element method under uniaxial tensile, simple shear, biaxial tensile, as well as combined tensile/shear loadings. The particle shapes change randomly from circular to regular n-sided polygon （3 ≤ n ≤ 10）; the particle alignments are determined through a sequentially random number stream and the particle locations are defined through the random sequential adsorption algorithm. The ductile failure in metal matrix and brittle failure in particles are described through damage models based on the stress triaxial indicator and maximum principal stress criterion, respectively, while the debonding behavior of interface between particles and matrix is simulated through cohesive elements. The simulation results show that, under different loadings, interface debonding is the dominated failure mechanism in MMCs and plastic deformation and ductile failure of matrix also play very important roles on the failure of MMCs.

关键词： Metal matrix composites Finite element analysis Damage Strength

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碱性介质中腐植酸电化学氧化动力学研究

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现代化工 2025年第1期45卷 207-213页

作者：冯晴晴何德民范玉强关珺大连理工大学化工学院辽宁大连116024

采用三电极体系的H型隔膜电解池对腐植酸(humic acid,HA)在碱性条件下的电化学氧化过程进行动力学研究,考察了温度、阳极电位、碱液质量浓度对电化学氧化反应的影响。结果表明,HA电化学氧化符合二级反应动力学模型,活化能为19.94 kJ/mol... 详细信息

采用三电极体系的H型隔膜电解池对腐植酸(humic acid,HA)在碱性条件下的电化学氧化过程进行动力学研究,考察了温度、阳极电位、碱液质量浓度对电化学氧化反应的影响。结果表明,HA电化学氧化符合二级反应动力学模型,活化能为19.94 kJ/mol,各反应条件对HA进一步氧化成高附加值的煤酸(CA)有不同程度的影响。对各反应条件下的氧化过程进行分析发现,温度影响分子间键能和双电层充放电速率;阳极电位影响相应的电流密度,进而影响电子转移效率;碱液质量浓度改变溶液的电导性。HA电化学氧化后分子结构发生改变,可为进一步研究煤电化学氧化这一复杂反应提供参考。

关键词：腐植酸碱性电化学氧化动力学反应条件

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On the consistency of two-phase local/nonlocal piezoelectric integral model

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Applied Mathematics and Mechanics(English Edition) 2021年第11期42卷 1581-1598页

作者： Yanming REN hai qing State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China

In this paper,we propose general strain-and stress-driven two-phase local/nonlocal piezoelectric integral models,which can distinguish the difference of nonlocal effects on the elastic and piezoelectric behaviors of *** nonlocal piezoelectric model is transformed from integral to an equivalent differential form with four constitutive boundary conditions due to the difficulty in solving intergro-differential equations *** nonlocal piezoelectric integral models are used to model the static bending of the Euler-Bernoulli piezoelectric beam on the assumption that the nonlocal elastic and piezoelectric parameters are coincident with each *** governing differential equations as well as constitutive and standard boundary conditions are *** is found that purely strain-and stress-driven nonlocal piezoelectric integral models are ill-posed,because the total number of differential orders for governing equations is less than that of boundary ***,the traditional nonlocal piezoelectric differential model would lead to inconsistent bending response for Euler-Bernoulli piezoelectric beam under different boundary and loading *** nominal variables are introduced to normalize the governing equations and boundary conditions,and the general differential quadrature method(GDQM)is used to obtain the numerical *** results from current models are validated against results in the *** is clearly established that a consistent softening and toughening effects can be obtained for static bending of the Euler-Bernoulli beam based on the general strain-and stress-driven local/nonlocal piezoelectric integral models,respectively.

关键词： nonlocal piezoelectric integral model softening effect toughening effect general differential quadrature method(GDQM)

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Nonlocal stress gradient formulation for damping vibration analysis of viscoelastic microbeam in thermal environment

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Applied Mathematics and Mechanics(English Edition) 2023年第5期44卷 773-786页

作者： hai qing Huidiao SONG State Key Laboratory of Mechanics and Control for Aerospace Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China

An integral nonlocal stress gradient viscoelastic model is proposed on the basis of the integral nonlocal stress gradient model and the standard viscoelastic model,and is utilized to investigate the free damping vibration analysis of the viscoelastic BernoulliEuler microbeams in thermal ***'s principle is used to derive the differential governing equations and corresponding boundary *** integral relations between the strain and the nonlocal stress are converted into a differential form with constitutive *** size-dependent axial thermal stress due to the variation of the environmental temperature is derived *** Laplace transformation is utilized to obtain the explicit expression for the bending deflection and *** the boundary conditions and constitutive constraints,one can get a nonlinear equation with complex coefficients,from which the complex characteristic frequency can be determined.A two-step numerical method is proposed to solve the elastic vibration frequency and the damping *** effects of length scale parameters,viscous coefficient,thermal stress,vibration order on the vibration frequencies,and critical viscous coefficient are investigated numerically for the viscoelastic Bernoulli-Euler microbeams under different boundary conditions.

关键词： damping vibration size effect integral nonlocal stress gradient model standard viscoelastic model Laplace transformation

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Two-phase nonlocal integral models with a bi-Helmholtz averaging kernel for nanorods

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Applied Mathematics and Mechanics(English Edition) 2021年第10期42卷 1379-1396页

作者： Pei ZHANG hai qing State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China

In this work,the static tensile and free vibration of nanorods are studied via both the strain-driven(Strain D)and stress-driven(Stress D)two-phase nonlocal models with a bi-Helmholtz averaging *** adjusting the limits of integration,the integral constitutive equation of the Fredholm type is converted to that of the Volterra type and then solved directly via the Laplace transform *** unknown constants can be uniquely determined through the standard boundary conditions and two constrained conditions accompanying the Laplace transform *** the numerical examples,the bi-Helmholtz kernel-based Strain D(or Stress D)two-phase model shows consistently softening(or stiffening)effects on both the tension and the free vibration of nanorods with different boundary *** effects of the two nonlocal parameters of the bi-Helmholtz kernel-based two-phase nonlocal models are studied and compared with those of the Helmholtz kernel-based models.

关键词： two-phase nonlocal integral model bi-Helmholtz kernel tensile analysis free vibration exact solution Laplace transform

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