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Current status of Mycoplasma pneumoniae infection in China

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World Journal of Pediatrics 2024年第1期20卷 1-4页

作者： Chao Yan guan-Hua Xue Han-qing Zhao Yan-Ling feng Jing-Hua Cui Jing Yuan Department of Bacteriology Capital Institute of PediatricsNo.2Yabao RoadBeijing 100020People's Republicof China

Mycoplasma pneumoniae(M.pneumoniae)is one of the most important pathogens for community-acquired pneumonia worldwide,especially in children and adolescents[1,2].M.pneumoniae is easily transmitted through droplets or direct contact in densely populated,enclosed,or poorly ventilated environments.The incubation period is 1-3 weeks,and it is contagious from the incubation period to a few weeks after clinical symptom relief.M.pneumoniae infection can occur in any season,and there are differences in the epidemic seasons among regions in China[3].The most suitable culture temperature for M.pneumoniae is between 35℃C and 37 C,and therefore,hot weather may make it survive longer in the environment and spread further.Infection is more common in autumn and winter in northern China,while it is more prevalent in summer and autumn in southern China.

关键词： winter weather autumn

Thermal stability of permafrost under U-shaped crushed rock embankment of the qinghai-Tibet Railway

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Advances in Climate Change Research 2024年第1期15卷 158-169页

作者： Kun-Ming XU guan-Li JIANG Ji CHEN qing-Bai WU State Key Laboratory of Frozen Soil Engineering Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China Beiluhe Observation Station of Frozen Soil Environment and Engineering Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China

The U-shaped crushed rock embankment(UCRE),of which widely utilized in the permafrost regions along the qinghai-Tibet Railway,has the capability to rapidly reduce the ground temperature of the underlying permafrost.However,there remains uncertainty regarding the adaptation of UCRE to climate change and its long-term cooling trend.This study focuses on nine UCRE monitoring sites along the qinghai-Tibet Railway to analyze the dynamic variations of the ground temperature underlying permafrost from 2006 to 2020.The efficiency of UCRE in stabilizing permafrost temperature in different permafrost zones is evaluated by considering the permafrost table,ground temperature,and MAGT,as well as the temperature difference between the top and bottom of the crushed rock layer and the ground temperature variation index(GTVI).The results show that UCRE is suitable for application in extremely unstable warm permafrost regions where the MAGT is higher than-0.5℃.Moreover,UCRE effectively diminishes the disparity in permafrost thermal stability between the sunny and shaded shoulders of the embankment.The short-term and long-term effect of cooling permafrost is experiencing a change related with permafrost stability.Notably,in stable cold permafrost regions with MAGT lower than-1.5℃,the long-term cooling effect of UCRE on permafrost seems to gradually di-minishes,but UCRE continues to fulfill the role of stabilizing the underlying permafrost thermal state over the long-term.These results show that UCRE can quickly restore and stabilize the thermal state of permafrost in the early stages of construction,and adapt to the influence of future climate change.The findings provide important guidance for understanding the variations of permafrost thermal stability beneath the embankment in permafrost regions,as well as for improving the embankment stability and operational safety of the qinghai-Tibet Railway.

关键词： qinghai-Tibet Railway U-shaped crushed rock embankment Climate change Permafrost zone Ground temperature variation index Long-term coolingrole

How Does Urban Shrinkage Affect Land Use Efficiency?A Case Study of Shrinking Cities in Northeast China

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Chinese Geographical Science 2024年第1期34卷 34-51页

作者： XIE Mingke feng Zhangxian SONG Yang guan Haoming WANG Shijun School of Geographical Sciences Northeast Normal UniversityChangchun130024China

The effect of urban shrinkage has gradually become a new topic.Theoretically,urban shrinkage may exert great influence on land use efficiency(LUE)through various urban subsystems,but there is currently limited research examining these pathways.Using the Super-SBM-Undesirable model and the Structural Equation Model(SEM),this study calculates the LUE of shrinking cities in Northeast China and simulates the process of urban shrinkage affecting LUE.To quantify the process of urban shrinkage affecting LUE,three mediation variables,namely the economy,public services,and innovation,are used as latent variables to apply SEM.The results show that urban shrinkage will affect LUE through a direct path and indirect paths.In the direct path,urban shrinkage leads to an improvement in LUE.In the indirect paths,the economy and innovation will transmit the negative effect of urban shrinkage on LUE,while public services will reverse this effect.An important contribution of this study is that it quantifies the paths of urban shrinkage affecting LUE,thereby expanding the understanding of urban shrinkage effect and laying a foundation for the sustainable development of shrinking cities.

关键词： urban shrinkage land use efficiency Super-SBM-Undesirable model Structural Equation Model(SEM) Northeast China

Multi-scale data joint inversion of minerals and porosity in altered igneous reservoirs—A case study in the South China Sea

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Petroleum Science 2024年第1期21卷 206-220页

作者： Xin-Ru Wang Bao-Zhi Pan Yu-Hang Guo qing-Hui Wang Yao guan College of Geo-exploration Science and Technology Jilin UniversityChangchun130046JilinChina Research Institute CNOOC Ltd.-ShenzhenShenzhen518000GuangdongChina

There are abundant igneous gas reservoirs in the South China Sea with significant value of research,and lithology classification,mineral analysis and porosity inversion are important links in reservoir evaluation.However,affected by the diverse lithology,complicated mineral and widespread alteration,conventional logging lithology classification and mineral inversion become considerably difficult.At the same time,owing to the limitation of the wireline log response equation,the quantity and accuracy of minerals can hardly meet the exploration requirements of igneous formations.To overcome those issues,this study takes the South China Sea as an example,and combines multi-scale data such as micro rock slices,petrophysical experiments,wireline log and element cutting log to establish a set of joint inversion methods for minerals and porosity of altered igneous rocks.Specifically,we define the lithology and mineral characteristics through core slices and mineral data,and establish an igneous multi-mineral volumetric model.Then we determine element cutting log correction method based on core element data,and combine wireline log and corrected element cutting log to perform the lithology classification and joint inversion of minerals and porosity.However,it is always difficult to determine the elemental eigenvalues of different minerals in inversion.This paper uses multiple linear regression methods to solve this problem.Finally,an integrated inversion technique for altered igneous formations was developed.The results show that the corrected element cutting log are in good agreement with the core element data,and the mineral and porosity results obtained from the joint inversion based on the wireline log and corrected element cutting log are also in good agreement with the core data from X-ray diffraction.The results demonstrate that the inversion technique is applicable and this study provides a new direction for the mineral inversion research of altered igneous formations.

关键词： Joint inversion Altered igneous rock Element correction method Lithology identification Multi mineral volume model

Clinical practice of sepsis-induced immunosuppression:Current immunotherapy and future options

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Chinese Journal of Traumatology 2024年第2期27卷 63-70页

作者： Fei Pei Bin Gu Shu-Min Miao Xiang-Dong guan Jian-feng Wu Department of Critical Care Medicine The First Affiliated HospitalSun Yat-sen UniversityGuangzhou510080China guangdong Clinical Research Center for Critical Care Medicine Guangzhou510080China

Sepsis is a potentially fatal condition characterized by the failure of one or more organs due to a disordered host response to infection.The development of sepsis is closely linked to immune dysfunction.As a result,immunotherapy has gained traction as a promising approach to sepsis treatment,as it holds the potential to reverse immunosuppression and restore immune balance,thereby improving the prognosis of septic patients.However,due to the highly heterogeneous nature of sepsis,it is crucial to carefully select the appropriate patient population for immunotherapy.This review summarizes the current and evolved treatments for sepsis-induced immunosuppression to enhance clinicians'understanding and practical application of immunotherapy in the management of sepsis.

关键词： Sepsis Sepsis-induced immunosuppression Immunotherapy Enrichment Classifier

Dynamic Equivalent Modeling for Black-box Microgrids Under Multi-operating-point by Using LSTM

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 639-648页

作者： Yunlu Li Josep M.Guerrero Junyou Yang Yajuan guan Guiqing Ma Jiawei feng School of Electrical Engineering Shenyang University of TechnologyShenyang 110819China Department of Energy Technology Center for Research on Microgrids(CROM)Aalborg University9220 Aalborg EastDenmark

Since the high penetration of distributed energy sources complicates the dynamics of electrical power systems,accurate dynamic models are indispensable for study on the transient behavior of the microgrid(MG).In some practices,the lack of full detailed information results in failure of dif-ferential equation based dynamic modeling,which leads to a demand for a black-box MG modeling method.It is a critical challenge to maintain the effectiveness of the black-box model under a wide operating range and various fault conditions.In this paper,inspired by the mathematical equivalence between the recurrent neural network(RNN)and differential-algebraic equations(DAEs),a dynamic equivalent modeling method,using long short-term memory(LSTM),is presented to tackle this challenge.At first,the modeling equivalence and advantages of our basic idea are explained.Then,modeling procedures,including data preparation and design guidelines,are presented.Finally,the proposed method is applied to a multi-microgrid testing system for performance evaluation.The results,under various scenarios,reveal that the proposed modeling method has an adequate capability for representing the dynamic behaviors of a black-box MG under grid fault and operating point changing conditions.Index Terms-Deep learning,dynamic behavior,dynamic equivalent model,microgrid,neural network.

关键词： Deep learning dynamic behavior dynamic equivalent model microgrid neural network

Revealing the role of pyramidal slip in the high ductility of Mg-Li alloy

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Journal of Magnesium and Alloys 2024年第3期12卷 1021-1025页

作者： Jing Xu Bo guan Yunchang Xin guangjie Huang Peidong Wu qing Liu International Joint Laboratory for Light Alloys College of Materials Science and EngineeringChongqing UniversityChongqing 400030China Key Laboratory for Light-weight Materials Nanjing Tech UniversityNanjing 210009China Department of Mechanical Engineering McMaster UniversityHamiltonON L8S 4L7Canada

The high ductility of Mg-Li alloy has been mainly ascribed to a high activity of pyramidalslip to accommodate plastic strain.In the present study,however,a quantitative analysis reveals that Li-addition can only slightly stimulate the activation of pyramidalslip under compression along the normal direction of a hot-rolled Mg-4.5 wt.%Li plate,with a relative activity of approximately 18%.Although the limited activity of pyramidalslip alone cannot accommodate a large plastic strain,it effectively reduces the number of{10.11}−{10.12}double twins,which are believed to be favorable sites for crack initiation.The evidently reduced activity of double twins leads to a lower cracking tendency,and therefore improves ductility.

关键词： Mg alloy Plasticity Plastic deformation Slip Twinning.

The reservoir characteristics and their controlling factors of the sublacustrine fan in the Paleogene Dongying Formation, Bohai Sea,China

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Journal of Palaeogeography 2024年第1期13卷 127-148页

作者： Xiao-Jun Pang guan-Min Wang Meng Zhao qing-Bin Wang Xue-Fang Zhang School of Geosciences China University of Petroleum(East China)QingdaoShandong 266580China Tianjin Branch of China National Offshore Oil Corporation Limited Tianjin 300459China

Sublacustrine fan is an important element in continental lacustrine basins and is significant for reservoir exploration. Oil and gas resources have been found in the sublacustrine fan sandstone reservoirs of the Paleogene Dongying Formation in the Bohai Sea. In this study, the characteristics of the sublacustrine fan reservoirs and the controlling factors are studied using information from logging, cores, physical properties,casting thin sections, X-ray diffraction of clay minerals, vitrinite reflectance, rock pyrolysis, manometry data,and 3D seismic data. The sublacustrine fans of the Dongying Formation in the LD10, QHD34, and BZ21 structures show high-quality reservoirs with porosity >15 % and permeability >5 m D. The main controlling factors of the high-quality reservoirs are attributed to the favorable sedimentary facies type and negligible compaction,and cementation, substantial dissolution of K-feldspar, overpressure, and the development of faults and fractures. A high-quality sublacustrine fan reservoir model has been established to explain how these factors affected the physical properties. The favorable targets for oil and gas exploration in the Dongying Formation of Bohai Sea include undercompacted sandy debris flow reservoirs showing the dissolution of K-feldspar, and the reservoirs which are connected to the source rocks by faults. This study provides insights to establish the relationship between sedimentology, diagenesis and reservoir quality. The results of this study are significant for the exploration and development of the sublacustrine fan sandstone reservoirs in the Bohai Sea and analogous sandstone reservoirs elsewhere.

关键词： Sublacustrine fan High-quality reservoir Dissolution Overpressure Fault Bohai Sea

Emulsifying property,antioxidant activity,and bitterness of soybean protein isolate hydrolysate obtained by Corolase PP under high hydrostatic pressure

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Food Science and Human Wellness 2024年第3期13卷 1271-1278页

作者： Haining guan Chunmei feng Min Ren Xiaojun Xu Dengyong Liu Xiaoqin Diao College of Food Science and Technology Bohai UniversityJinzhou 121013China

Enzymatic hydrolysis of proteins can enhance their emulsifying properties and antioxidant activities.However,the problem related to the hydrolysis of proteins was the generation of the bitter taste.Recently,high hydrostatic pressure(HHP)treatment has attracted much interest and has been used in several studies on protein modification.Hence,the study aimed to investigate the effects of enzymatic hydrolysis by Corolase PP under different pressure treatments(0.1,100,200,and 300 MPa for 1-5 h at 50℃)on the emulsifying property,antioxidant activity,and bitterness of soybean protein isolate hydrolysate(SPIH).As observed,the hydrolysate obtained at 200 MPa for 4 h had the highest emulsifying activity index(47.49 m^(2)/g)and emulsifying stability index(92.98%),and it had higher antioxidant activities(44.77%DPPH free radical scavenging activity,31.12%superoxide anion radical scavenging activity,and 61.50%copper ion chelating activity).At the same time,the enhancement of emulsion stability was related to the increase of zeta potential and the decrease of mean particle size.In addition,the hydrolysate obtained at 200 MPa for 4 h had a lower bitterness value and showed better palatability.This study has a broad application prospect in developing food ingredients and healthy foods.

关键词： Soybean protein isolate High hydrostatic pressure Emulsification Antioxidant Bitter taste