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Identifying the risk factors for pancreatic fistula after laparoscopic pancreaticoduodenectomy in patients with pancreatic cancer

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1609-1617页

作者： Hang Xu qing-cai meng Jie Hua Wei Wang Department of Pancreatic Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China

BACKGROUND Laparoscopic pancreaticoduodenectomy(LPD)is a surgical procedure for treating pancreatic cancer;however,the risk of complications remains high owing to the wide range of organs involved during the surgery and the difficulty of *** fistula(PF)is a major complication that not only increases the risk of postoperative infection and abdominal hemorrhage but may also cause multi-organ failure,which is a serious threat to the patient’s *** study hypothesized the risk factors for PF after *** To identify the risk factors for PF after laparoscopic pancreatoduodenectomy in patients with pancreatic *** We retrospectively analyzed the data of 201 patients admitted to the Fudan University Shanghai Cancer Center between August 2022 and August 2023 who underwent LPD for pancreatic *** the basis of the PF’s incidence(grades B and C),patients were categorized into the PF(n=15)and non-PF groups(n=186).Differences in general data,preoperative laboratory indicators,and surgery-related factors between the two groups were compared and analyzed using multifactorial logistic regression and receiver-operating characteristic(ROC)curve *** The proportions of males,combined hypertension,soft pancreatic texture,and pancreatic duct diameter≤3 mm;surgery time;body mass index(BMI);and amylase(Am)level in the drainage fluid on the first postoperative day(Am>1069 U/L)were greater in the PF group than in the non-PF group(P24.91 kg/m²[odds ratio(OR)=13.978,95%confidence interval(CI):1.886-103.581],hypertension(OR=8.484,95%CI:1.22-58.994),soft pancreatic texture(OR=42.015,95%CI:5.698-309.782),and operation time>414 min(OR=15.41,95%CI:1.63-145.674)were risk factors for the development of PF after LPD for pancreatic cancer(all P<0.05).The areas under the ROC curve for BMI,

关键词： Pancreatic cancer Laparoscopy Pancreaticoduodenectomy Pancreatic fistula Risk factors Receiver-operating characteristic curve

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Electron Beam-Physical Vapor Deposited TiAl-based Laminated Composite Sheet with Nb Layer Toughening

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Chinese Journal of Aeronautics 2006年第B12期19卷 5-8页

作者： ZHANG De-ming CHEN Gui-qing HAN Jie-cai meng Song-he Center for Composite Materials Harbin Institute of Technology Harbin 150080 China

The TiAl-based laminated composite sheet of 150 mm × 100 mm × 0.2 mm, with 24 TiAl layers and 23 Nb layers laid alternately one on another, was successfully fabricated using the electron beam-physical vapor deposition （EB-PVD） method. The microstructure and properties of the sheet were investigated on an atomic force microscope （AFM）, a scanning electron microscope （SEM） and a tensile testing machine. The results indicate that the evenly distributed Nb layers are well joined with the TiAl layers, and the interfaces between layers are transparent, and every interlayer spacing is of about 8μm. The fractures appear to be a mixture of intergranular fractures and somewhat ductile quasi-cleavage ones. Despite its slight influence on ultimate tensile strength, the inserts of Nb layers efficiently increase the room temperature ductility of TiAl-based alloys due to the crack deflection effect.

关键词： EB-PVD TiAl-based alloys sheet TiAl/Nb laminated composites microstructure and properties

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NUMERICAL COMPUTATION OF PRESSURE GRADIENT FOR THE FLOW OF POWER-LAW FLUID IN ANNULUS WITH INNER CYLINDER EXECUTING A PLANETARY MOTION

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Journal of Hydrodynamics 2009年第5期21卷 699-704页

作者： CUI Hai-qing cai meng ZHANG Shu-yun XIU De-yan Key Laboratory for Enhanced Oil and Gas Recovery of Ministry of Education Daqing Petroleum Institute Daqing 163318 China Exploration and Development Research Institute of Jidong Oilfield PetroChina Tangshan 063000 China

With the governing equations for the flow of the power-law fluid in annulus with the inner cylinder executing a planetary motion being transformed by using the undetermined coefficient method, the formula of pressure gradient for this flow under the given flow rate and the relevant numerical calculation method are given in this article. Through the experiments on the flow of Hydrolyzed Polyacrylamide （HPAM） aqueous solution which can be regarded as a power-law fluid, the calculated results of the pressure gradient values are compared with measured data, the mean relative error between them is smaller than 5%, which verifies the results presented in this article.

关键词： power-law fluid planetary motion annulus pressure gradient numerical calculation

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Segment-wise learning control for trajectory tracking of robot manipulators under iteration-dependent periods

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Science China(Information Sciences) 2024年第3期67卷 155-166页

作者： Fan ZHANG Deyuan meng Kaiquan cai The Seventh Research Division Beihang University School of Automation Science and Electrical Engineering Beihang University School of Electronics and Information Engineering Beihang University

This paper is concerned with the amplitude boundedness problem of adaptive iterative learning control(AILC) for robot manipulators operating with iteration-dependent periods. By introducing virtual memory slots for storing historical data, a practical AILC method is proposed to achieve the segmentwise learning. This method requires less memory storage for historical information of previous iterations,especially in comparison with that of the conventional AILC methods using point-wise learning *** is shown that not only the energy boundedness but also the amplitude boundedness of estimates and inputs of practical AILC can be guaranteed. Moreover, the practical AILC method can achieve the perfect tracking objective regardless of iteration-dependent periods when the robot manipulators have a persistent full learning property. In addition, a solution to the visual manipulator platform is provided and deployed based on Coppeliasim and Matlab, which helps to show the amplitude boundedness of learning results and the perfect tracking performances of the proposed practical AILC method for robot manipulators.

关键词： amplitude boundedness iteration-dependent period iterative learning control robot manipulator segment-wise virtual memory slot

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WEAK APPROXIMATIONS OF STOCHASTIC PARTIAL DIFFERENTIAL EQUATIONS WITH FRACTIONAL NOISE

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Journal of Computational Mathematics 2024年第3期42卷 735-754页

作者： meng cai Siqing Gan Xiaojie Wang School of Mathematics and Statistics HNP-LAMACentral South UniversityChangshaChina

This paper aims to analyze the weak approximation error of a fully discrete scheme for a class of semi-linear parabolic stochastic partial differential equations(SPDEs)driven by additive fractional Brownian motions with the Hurst parameter H∈(1/2,1).The spatial approximation is performed by a spectral Galerkin method and the temporal discretization by an exponential Euler *** far as we know,the weak error analysis for approximations of fractional noise driven SPDEs is absent in the literature.A key difficulty in the analysis is caused by the lack of the associated Kolmogorov *** the present work,a novel and efficient approach is presented to carry out the weak error analysis for the approximations,which does not rely on the associated Kolmogorov equations but relies on the Malliavin *** the best of our knowledge,the rates of weak convergence,shown to be higher than the strong convergence rates,are revealed in the fractional noise driven SPDE setting for the first *** examples corroborate the claimed weak orders of convergence.

关键词： Parabolic SPDEs Fractional Brownian motion Weak convergence rates Spec-tral Galerkin method Exponential Euler method Malliavin calculus

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Effect of Fluoride on the Ion-association of Calcium Phosphate and Crystallization of Hydroxyapatite

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Journal of Wuhan University of Technology(Materials Science) 2024年第4期39卷 831-838页

作者：宋昊月 cai meng 袁萍邹朝勇 School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China

Using a titration setup to accurately control the reaction conditions and in situ monitor the reaction,we showed that fluoride exhibited negligible effects on the ion association process of calcium and phosphate and the formation of ACP nanospheres in a buffer solution with constant ionic ***,the stability of ACP increased with increasing fluoride concentration,which was ascribed to the inhibitory effect of fluoride on the aggregation of ACP nanospheres and the nucleation of nanocrystals on the surface of ACP ***,fluoride could inhibit the lateral growth of HAP nanosheets and promote the formation of rod-like *** results further improve our understanding of the crystallization pathway of HAP crystals and the regulatory effects of fluoride.

关键词： crystallization amorphous calcium phosphate hydroxyapatite fluoride

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Monocyte to High-density Lipoprotein Cholesterol Ratio as a Predictor of Nonalcoholic Fatty Liver Disease in Childhood Obesity

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Current Medical Science 2024年第4期44卷 692-697页

作者： Jun-feng ZHANG Feng-qing cai Xiu-cai ZHANG qing YE Department of Laboratory Medicine Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou310052China

Objective Inflammation is involved in the development and progression of nonalcoholic fatty liver disease(NAFLD).The monocyte to high-density lipoprotein cholesterol ratio(MHR)has emerged as a marker for various inflammation-related *** aim of the present study was to investigate the association between the MHR and NAFLD in a population with childhood *** Based on hepatic ultrasound,a total of 504 children with obesity(357 with NAFLD and 147 without NAFLD)were included in the *** correlation between the MHR and NAFLD risk factors was assessed by Pearson’s and Spearman’s *** stepwise logistic regression analyses were conducted to explore the association between the MHR and the risk of *** The MHR in patients with NAFLD was significantly greater than that in patients without NAFLD[0.52(0.44-0.67)versus 0.44(0.34-0.57),P<0.001].Multivariate stepwise logistic regression analysis demonstrated that the MHR[odds ratio(OR):1.033,95%confidence interval(CI):1.015-1.051;P<0.001]was an independent predictor of NAFLD in childhood obesity patients,as were age(OR:1.205,95%CI:1.059-1.371;P=0.005],waist circumference[OR:1.037,95%CI:1.008-1.067;P=0.012],and alanine transaminase[OR:1.067,95%CI:1.045-1.089;P<0.001].Additionally,MHR quartiles showed a significant positive association with the incidence of NAFLD after adjusting for potential confounding *** The present study showed that the MHR may serve as an available and useful indicator of NAFLD in individuals with childhood obesity.

关键词： nonalcoholic fatty liver disease obesity monocyte-to-high-density lipoprotein ratio marker

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Clustered spikelets 4,encoding a putative cytochrome P450 protein CYP724B1,is essential for rice panicle development

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Chinese Science Bulletin 2014年第31期59卷 4050-4059页

作者： Min Guo Yi-Hao Yang Min Liu qing-cai meng Xiu-Hong Zeng Ling-Xia Dong Shu-Zhu Tang Ming-Hong Gu Chang-Jie Yan Jiangsu Key Laboratory of Crop Genetics and Physiology/ Co-Innovation Center for Modern Production Technology of Grain Crops Key Laboratory of Plant Functional Genomics of the Ministry of EducationYangzhou University

Rice(Oryza sativa L.)inflorescence(panicle)architecture is an important agronomic trait,serving as one of the determinants of rice yield.A number of genes related to panicle development have been cloned and functionally characterized so ***,more information is needed for fully understanding of the mechanism underlying the panicle *** the present study,we identified a clustered spikelets 4(cl4)mutant in the 93-11 genetic *** to its wild-type 93-11,cl4 mutant has a typical clustered spikelets phenotype with all primary branches clustered on the base of the main rachis and 2–3abnormal spikelets clustered on the primary ***,cl4 mutant also shows shorter plant height than that of the wild ***-based cloning strategy is performed to clone the CL4 *** a result,CL4 is demonstrated to encode a putative cytochrome P450 protein CYP724B1,which is involved in brassinosteroid *** confirm our mapping result,the CL4 RNAi transgenic plants are *** the transgenic plants also show similar phenotype as the cl4 *** results provide strong evidence that CL4 plays an important role in rice panicle development as well as plant height regulation.

关键词：细胞色素P450 水稻产量小穗集群蛋白编码稻穗转基因植物

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Validation and head-to-head comparison of four models for predicting malignancy of intraductal papillary mucinous neoplasm of the pancreas: A study based on endoscopic ultrasound findings

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World Journal of Gastrointestinal Oncology 2019年第11期11卷 1043-1053页

作者： Jie Hua Bo Zhang Xiu-Jiang Yang Yi-Yin Zhang Miao-Yan Wei Chen Liang qing-cai meng Jiang Liu Xian-Jun Yu Jin Xu Si Shi Department of Pancreatic Surgery Fudan University Shanghai Cancer CenterDepartment of OncologyFudan University Shanghai Medical CollegeShanghai Pancreatic Cancer InstituteShanghai 200032China Department of Endoscopy Fudan University Shanghai Cancer CenterShanghai 200032China

BACKGROUND Several models are currently available for predicting the malignancy of pancreatic intraductal papillary mucinous neoplasm(IPMN),namely,the Pancreatic Surgery Consortium(PSC),the Japan Pancreas Society(JPS),the Johns Hopkins Hospital(JHH),and the Japan-Korea(JPN-KOR)***,a head-to-head comparison that shows which model is more accurate for this individualized prediction is *** To perform a head-to-head comparison of the four models for predicting the malignancy of pancreatic *** A total of 181 patients with IPMN who had undergone surgical resection were identified from a prospectively maintained *** characteristics of IPMN in patients were recorded from endoscopic ultrasound imaging data and report *** performance of all four models was examined using Harrell’s concordance index(C-index),calibration plots,decision curve analyses,and diagnostic *** Of the 181 included patients,94 were categorized as having benign disease,and the remaining 87 were categorized as having malignant *** C-indexes were 0.842[95%confidence interval(CI):0.782-0.901],0.704(95%CI:0.626-0.782),0.754(95%CI:0.684-0.824),and 0.650(95%CI:0.483-0.817)for the PSC,JPS,JHH,and JPN-KOR models,*** plots showed that the PSC model had the least pronounced departure from ideal *** the remaining three models,the JPS and JHH models underestimated the probability of malignancy,while the JPN-KOR model overestimated the malignant potential of branch *** curve analysis revealed that the PSC model resulted in a better clinical net benefit than the three other *** tests also showed a higher accuracy(0.801)for the PSC *** The PSC model exhibited the best performance ***,the PSC model should be considered the best tool for the individualized prediction of malignancy in patients with pancreatic IPMN.

关键词： Intraductal papillary mucinous neoplasms Prediction model Endoscopic ultrasound Mural nodules Malignancy

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Tailoring sulfur-doped and nitrogen-defective carbon nitride nanosheets for efficient photo-controlled radical polymerizations

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Science China Chemistry 2024年第7期67卷 2325-2334页

作者： Xue Li meng Kai Xu Yuan Huang Tao cai Key Laboratory of Biomedical Polymers of Ministry of Education College of Chemistry and Molecular SciencesWuhan UniversityWuhan 430072China Wuhan University Shenzhen Research Institute Shenzhen 518057China

Despite the challenges that remain,the synergistic adjustment of various microstructures and photochemical parameters of graphitic carbon nitride(g-C_(3)N_(4))in photocatalytic reactions holds promises for improving catalytic efficiency and reducing energy ***,sulfur-doped and nitrogen-defective g-C_(3)N_(4)(n-SC_(3)N_(x))nanosheets were designed and elaborately *** resultant n-SC_(3)N_(x)possessed a precisely defined 2D layer structure with extensive porosity and incremental specific surface *** photoinduced electron transfer-reversible addition-fragmentation chain transfer(PET-RAFT)polymerization of vinyl monomers with low dispersity,excellent temporal control and high chain-end fidelity was achieved under mild blue light irradiation in a nondegassed *** to their ultrathin nanostructures with nitrogen defects and sulfur dopants,n-SC_(3)N_(x)was capable of catalyzing RAFT polymerization in aqueous solutions at significantly accelerated rates,which were nearly 8 times faster compared to bulk g-C_(3)N_(4).The ease of separation and efficient reusability in subsequent polymerizations was enabled by the heterogeneous nature of n-SC_(3)N_(x).The appeal of this approach was illustrated by the fact that utilizing a reusable and metal-free photocatalyst in aqueous environments allowed for the synthesis of polymers with molecular weight up to 300 kg mol^(-1) and a dispersity of 1.32.

关键词： graphitic carbon nitride nitrogen defects sulfur dopants PET-RAFT polymerization recyclability

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