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Identification of forensically important blow fly species （Diptera： Calliphoridae） in China by mitochondrial cytochrome oxidase I gene differentiation

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Insect Science 2011年第5期18卷 554-564页

作者： Qin-Lai Liu Ji-Feng cai Yun-Feng Chang Yan Gu Ya-Dong Guo Xing-Hua Wang Ji-Fang Weng Ming Zhong Xiang Wang Li Yang Kun-Lu Wu Ling-Mei Lan Jiang-Feng Wang Yao-qing Chen School of Basic Medical Sciences Central South University Second Xiang-Ya Hospital of Central South University The Changsha Public Security Bureau in Hunan Changsha Hunan Department of Forensic Science and Technology Guangdong Police College Guangdong China

Unambiguous and rapid sarcosaphagous insect species identification is an essential requirement for forensic investigations. Although some insect species are difficult to classify morphologically, they can be effectively identified using molecular methods based on similarity with abundant authenticated reference DNA sequences in local databases. However, local databases are still relatively incomplete in China because of the large land area with distinct regional conditions. In this study, 75 forensically important blow flies were collected from 23 locations in 16 Chinese provinces, and a 278-bp segment of the cytochrome oxidase subunit I gene of all specimens was successfully sequenced. Phylogenetic analysis of the sequenced segments showed that all Calliphorid specimens were properly assigned into nine species with relatively strong supporting values, thus indicating that the 278-bp cytochrome oxidase subunit one region is suitable for identification of Calliphorid species. The clear difference between intraspecific threshold and interspecific divergence confirmed the potential of this region for Calliphorid species identification, especially for distinguishing between morphologically similar species. Intraspecific geographic variations were observed in Lucilia sericata （Meigen, 1826） and Lucilia caesar （Linnaeus, 1758）.

关键词： Calliphoridae China cytochrome oxidase subunit I (COl) forensic entomology species identification

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移动机器人路径规划强化学习的初始化

控制理论与应用 2012年第12期29卷 1623-1628页

作者：宋勇李贻斌李彩虹山东大学控制科学与工程学院山东济南250061 山东大学(威海)机电与信息工程学院山东威海264209 山东理工大学计算机科学与技术学院山东淄博255012

针对现有机器人路径规划强化学习算法收敛速度慢的问题,提出了一种基于人工势能场的移动机器人强化学习初始化方法.将机器人工作环境虚拟化为一个人工势能场,利用先验知识确定场中每点的势能值,它代表最优策略可获得的最大累积回报.例... 详细信息

针对现有机器人路径规划强化学习算法收敛速度慢的问题,提出了一种基于人工势能场的移动机器人强化学习初始化方法.将机器人工作环境虚拟化为一个人工势能场,利用先验知识确定场中每点的势能值,它代表最优策略可获得的最大累积回报.例如障碍物区域势能值为零,目标点的势能值为全局最大.然后定义Q初始值为当前点的立即回报加上后继点的最大折算累积回报.改进算法通过Q值初始化,使得学习过程收敛速度更快,收敛过程更稳定.最后利用机器人在栅格地图中的路径对所提出的改进算法进行验证,结果表明该方法提高了初始阶段的学习效率,改善了算法性能.

关键词：移动机器人强化学习人工势能场路径规划 Q值初始化

激光与近相对论临界密度薄层相互作用产生大电量高能电子束

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物理学报 2017年第7期66卷 342-348页

作者：王剑蔡达锋赵宗清谷渝秋内江师范学院物理学与电子信息工程学院内江641110 中国工程物理研究院激光聚变研究中心绵阳621900

研究了激光与近相对论临界密度等离子体薄层相互作用时所产生的高能电子束的主要特征,包括平均有效温度以及截止能量等.实验结果表明,电子束的电量超过nC量级,平均有效温度可达8 MeV以上.PIC数值模拟证明,近相对论临界密度等离子体内,... 详细信息

研究了激光与近相对论临界密度等离子体薄层相互作用时所产生的高能电子束的主要特征,包括平均有效温度以及截止能量等.实验结果表明,电子束的电量超过nC量级,平均有效温度可达8 MeV以上.PIC数值模拟证明,近相对论临界密度等离子体内,相对论自透明效应和激光钻孔效应共同形成一条磁化等离子体通道,电子与激光将在角向磁场的协助下发生Betatron共振.激光可将电子直接加速到很高能量,因此电子束平均有效温度("斜坡温度")远远超过Wilks定标率预计的平均温度.该研究为产生高亮度X射线源提供了一种新的可能途径.

关键词：近临界密度等离子体薄层泡沫靶 Betatron共振加速

Research progress of yoga in symptom management of cancer patients

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TMR Non-Drug Therapy 2022年第2期5卷 29-33页

作者： Guo-qing Liu Jing-Yi Han Wen-Jing song Ying Wang Graduate School Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Critical Medicine Tianjin First Central HospitalTianjin 300192China Nursing Department Tianjin First Central HospitalTianjin 300192China.

The survival rate of cancer patients is rising,but the treatment of cancer will bring a series of physiological and psychological symptoms to patients,which will seriously affect the quality of life of *** a complementary and alternative therapy,yoga is more and more used in symptom management and quality of life improvement of cancer *** paper introduces the overview,implementation methods and application status of yoga,summarizes the application effect of yoga in the symptom management of cancer patients,analyzes the shortcomings in the application process at this stage,and puts forward the prospect,in order to provide a reference for the better application of yoga in the symptom management of cancer patients in the future.

关键词： yoga cancer symptom management review

Development of Simple Functional Markers for Low Glutelin Content Gene 1 (Lgc1) in Rice (Oryza sativa)

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Rice science 2010年第3期17卷 173-178页

作者： CHEN Tao TIAN Meng-xiang ZHANG Ya-dong ZHU Zhen ZHAO Ling ZHAO qing-yong LIN Jing ZHOU Li-hui WANG cai-lin Jiangsu High Quality Rice Research and Development Center Institute of Food Crops Jiangsu Academy of Agricultural SciencesNanjing 210014 China＂ #These authors contributed equally to this paper

Rice with low glutelin content is suitable as functional food for patients affected by kidney failure. Low glutelincontent gene Lgc1 in rice has a 3.5-kb deletion between two highly similar glutelin genes GluB4 and GluB5, which locates on the short arm of chromosome 2. To improve the selection efficiency in low glutelin-content rice breeding, two molecular markers designated as InDel-Lgc1-1 and InDel-Lgc1-2 were developed to detect the low glutelin-content gene Lgc1. A double PCR detection indicated that combined use of the two markers could easily distinguish the genotypes of Lgc1 from different rice varieties. Therefore, as a simple and low-cost technique, the molecular marker could be widely used to identify different varieties with Lgc1 gene and applied in marker-assisted selection of low glutelin-content rice.

关键词： Oryza sativa low glutelin-content gene functional marker double polymerase chain reaction

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适用于弹黏塑性本构模型的修正切面算法

岩土工程学报 2020年第2期42卷 253-259页

作者：李舰蔡国庆尹振宇北京交通大学城市地下工程教育部重点实验室北京100044 北京交通大学土木建筑工程学院北京100044 香港理工大学土木与环境工程学系香港

针对弹黏塑性本构模型将原始切面算法进行了修正。该弹黏塑性本构模型结合了修正剑桥模型和过应力理论。首先对弹黏塑性本构模型的应力–应变关系式进行了调整,基于过应力理论给出了动态加载面硬化参数的演化方程。其次,利用切面算法对... 详细信息

针对弹黏塑性本构模型将原始切面算法进行了修正。该弹黏塑性本构模型结合了修正剑桥模型和过应力理论。首先对弹黏塑性本构模型的应力–应变关系式进行了调整,基于过应力理论给出了动态加载面硬化参数的演化方程。其次,利用切面算法对整理后应力–应变关系式进行了数值实现。在弹性试算过程中,该算法假设黏塑性应变率为常数,以此确保时间增量引起的当前应力点与动态加载面间的偏离。在塑性修正过程中,对动态加载面函数进行泰勒级数展开,依此获得黏塑性应变率增量。再次,提出了一种自动分步方法,有效地稳定了大应变步情况下算法的计算精度和收敛性。最后,对变应变率的固结试验和三轴剪切不排水试验进行了模拟,分析了修正切面算法的计算能力。

关键词：黏塑性本构模型切面算法半隐式算法数值积分

基于自适应高斯混合模型特征映射的说话人确认

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模式识别与人工智能 2009年第3期22卷 417-421页

作者：杨世清戴蓓蒨许敏强刘青松中国科学技术大学电子科学与技术系合肥230027

为了解决电话语音说话人确认系统中信道非线性失真导致系统性能下降的问题,提出一种消除信道影响的特征映射方法.采用高斯混合模型建立语音模型,通过最大后验概率自适应某种信道的语音模型,两种模型间相应高斯类的差异描述了该信道对于... 详细信息

为了解决电话语音说话人确认系统中信道非线性失真导致系统性能下降的问题,提出一种消除信道影响的特征映射方法.采用高斯混合模型建立语音模型,通过最大后验概率自适应某种信道的语音模型,两种模型间相应高斯类的差异描述了该信道对于不同语音的影响.由此得出信道映射规则进行参数补偿,消除训练和测试语音中不匹配的影响.在NIST 1999年和2004年男性说话人的数据库上进行的实验表明,此方法使系统的等错误率分别改善了14.7%和15.18%.

关键词：说话人确认信道失配特征映射(FM) 最大后验概率(MAP) 信道映射规则

Relationship between Tissue Distributions of Modified Wuzi Yanzong Prescription(加味五子衍宗方) in Rats and Meridian Tropism Theory

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Chinese Journal of Integrative Medicine 2018年第2期24卷 117-124页

作者： WANG Lin-lin LI Wei-wei WU cai-sheng ZHANG Jin-lan song Yi-xiang song Fang-jiao FU Hong LIU Geng-xin WANG Xue-mei Integrated Laboratory of Traditional Chinese Medicine and Western Medicine Peking University First Hospital Beijing 100034 China Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100050 China

Objective： To investigate the relationship between tissue distributions of modified Wuzi Yanzong prescription（加味五子衍宗方, MWP） in rats and meridian tropism theory. Methods： A high-performance liquid chromatography with Fourier transform-mass spectrometry（HPLC-FT） method was used to identify the metabolites of MWP in different tissues of rats after continued oral administration of MWP for 7 days. The relationship between MWP and meridian tropism theory was studied according to the tissue distributions of the metabolites of MWP in rats and the relevant literature. Results： Nineteen metabolites, mainly flavanoid compounds, were detected in the different rat tissues and classified to each herb in MWP. Further, it was able to establish that the tissue distributions of the metabolites of MWP were consistent with the descriptions of meridian tropism of MWP available in literature, this result might be useful in clarifying the mechanism of MWP on meridian tropism. In the long run, these data might provide scientific evidence of the meridian tropism theory to further promote the reasonable, effective utilization, and modernization of Chinese medicine. Conclusion： The tissue distributions of MWP in vivo were consistent with the descriptions of meridian tropism of MWP.

关键词： modified Wuzi Yanzong Prescription Chinese medicine tissue distributions meridian tropism high-performance liquid chromatography Fourier transform mass spectrometry

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基于知识的中药制药企业MES

系统工程理论与实践 2012年第1期32卷 164-172页

作者：黄海松谢庆生李少波袁庆霓贵州大学教育部现代制造技术重点实验室贵阳550003

针对中药制造企业生产运行、管理很大程度上依赖于经验,信息传递不及时、不全面,管理与生产脱节,生产指挥滞后等问题,首先分析了中药制药企业对MES系统的需求,并在此基础上,提出了以优化整个生产过程为核心的基于知识的中药制药企业MES... 详细信息

针对中药制造企业生产运行、管理很大程度上依赖于经验,信息传递不及时、不全面,管理与生产脱节,生产指挥滞后等问题,首先分析了中药制药企业对MES系统的需求,并在此基础上,提出了以优化整个生产过程为核心的基于知识的中药制药企业MES系统,给出了系统的功能模型并详细阐述了各功能模块.然后重点研究了系统构建的关键技术:知识的提取、知识的融合、知识的重用、生产过程优化等.该系统采用开放性的、可扩展的、模块化的、面向对象的体系结构,能实现生产过程的最优计划与调度、药品批次的跟踪、设备的预测性维护等功能,已在贵州某中药厂进行了应用验证,应用效果良好.

关键词：中药知识获取知识重用实时数据库模块 MES 生产过程优化