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Real-time Abnormal Detection of GWAC Light Curve based on Wavelet Transform Combined with GRU-Attention

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Research in Astronomy and Astrophysics 2024年第5期24卷 151-168页

作者： Hao Li qing Zhao Long shao Tao Liu Chenzhou Cui Yunfei Xu College of Artifcial Intelligence Tianjin University of Science and TechnologyTianjin 300457China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China

Nowadays, astronomy has entered the era of Time-Domain Astronomy, and the study of the time-varying light curves of various types of objects is of great significance in revealing the physical properties and evolutionary history of celestial bodies. The Ground-based Wide Angle Cameras telescope, on which this paper is based, has observed more than 10 million light curves, and the detection of anomalies in the light curves can be used to rapidly detect transient rare phenomena such as microgravity lensing events from the massive data. However, the traditional statistically based anomaly detection methods cannot realize the fast processing of massive data. In this paper, we propose a Discrete Wavelet(DW)-Gate Recurrent Unit-Attention(GRU-Attention) light curve warning model. Wavelet transform has good effect on data noise reduction processing and feature extraction, which can provide richer and more stable input features for a neural network, and the neural network can provide more flexible and powerful output model for wavelet transform. Comparison experiments show an average improvement of 61% compared to the previous pure long-short-term memory unit(LSTM) model, and an average improvement of 53.5% compared to the previous GRU model. The efficiency and accuracy of anomaly detection in previous paper work are not good enough, the method proposed in this paper possesses higher efficiency and accuracy,which incorporates the Attention mechanism to find out the key parts of the light curve that determine the anomalies. These parts are assigned higher weights, and in the actual anomaly detection, the star is detected with83.35% anomalies on average, and the DW-GRU-Attention model is compared with the DW-LSTM model, and the detection result f1 is improved by 5.75% on average, while having less training time, thus providing valuable information and guidance for astronomical observation and research.

关键词： methods data analysis-stars variables general-techniques photometric

Mapping quantitative trait loci associated with starch paste viscosity attributes by using double haploid populations of rice (Oryza sativa L.)

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Journal of Integrative Agriculture 2020年第7期19卷 1691-1703页

作者： Tahmina SHAR SHENG Zhong-hua Umed ALI Sajid FIAZ WEI Xiang-jin XIE Li-hong JIAO Gui-ai Fahad ALI shao Gao-neng HU Shi-kai HU Pei-song TANG shao-qing State Key Laboratory of Rice Biology/Key Laboratory of Rice Biology and Breeding Ministry of Agriculture/China National Rice Research InstituteHangzhou 310006P.R.China

The paste viscosity attributes of starch,measured by rapid visco analyzer(RVA),are important factors for the evaluation of the cooking and eating qualities of rice in breeding *** determine the genetic roots of the paste viscosity attributes of rice grains,quantitative trait loci(QTLs)associated with the paste viscosity attributes were mapped,using a double haploid(DH)population derived from Zhongjiazao 17(YK17),a super rice variety,crossed with D50,a tropic japonica ***-four QTLs,for seven parameters of the RVA profiles,were identified in three planting *** 54 QTLs were located on all of the 12 chromosomes,with a single QTL explaining 5.99 to 47.11%of phenotypic *** the QTLs identified,four were repeatedly detected under three environmental conditions and the other four QTLs were repeated under two *** of the QTLs detected for peak viscosity(PKV),trough viscosity(TV),cool paste viscosity(CPV),breakdown viscosity(BDV),setback viscosity(SBV),and peak time(PeT)were located in the interval of RM 6775-RM 3805 under all three environmental conditions,with the exception of pasting temperature(PaT).For digenic interactions,eight QTLs with six traits were identified for additivexenvironment interactions in all three planting *** epistatic interactions were estimated only for PKV,SBV and *** present study will facilitate further understanding of the genetic architecture of eating and cooking quality(ECQ)in the rice quality improvement program.

关键词： RVA profiles eating and cooking quality(ECQ) quantitative trait loci(QTL) DH population rice

Efficacy and safety of oral Chinese herbal medicine combined with nucleoside antiviral drugs against recurrent genital herpes:a systematic review and meta-analysis

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Traditional Medicine Research 2022年第1期7卷 53-63页

作者： Tian-Li Liu Tong Liu Xi-Ming Jin qing-qing shao Wen-Jia Wang Cong Huang Zhuo Chen Ping Yuan Institute of Integrated Traditional Chinese and Western Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Biochemistry and Molecular Biology School of Basic MedicineHuazhong University of Science and TechnologyWuhan 430030China

Background:To compare the efficacy and safety of Chinese herbal medicine combined with nucleoside antiviral drugs and nucleoside antiviral drugs alone in treating recurrent genital ***:PubMed,Embase,Web of Science,Cochrane Library,Chinese Biomedical Literature Database,China National Knowledge Internet,VIP Database,and Wanfang Data were searched from inception to April *** controlled trials on the efficacy and safety of oral Chinese herbal medicine combined with nucleoside antiviral drugs for recurrent genital herpes were *** included trials were independently assessed by two reviewers with the Cochrane risk-of-bias tool,and a meta-analysis was conducted using Review Manager ***:Compared with the use of nucleoside antiviral drugs alone,combination therapy with oral Chinese herbal medicine plus nucleoside antiviral drugs effectively reduced the herpes recurrence rate after the end of treatment(3 months:P=0.0002;6 months:P<0.00001;1 year:P<0.00001)and the number of recurrences each year(P<0.00001),improved the recurrent Genital Herpes Quality of Life Questionnaire score(P<0.00001),and regulated the levels of interferon-γ,interleukin-2,tumor necrosis factor-α,and T lymphocyte subsets in the peripheral blood,and the difference was statistically *** subgroups reported mixed results with respect to the efficacy in the short *** incidence of adverse reactions and the time of symptom disappearance between the two groups were not significantly ***:Chinese herbal medicine combined with nucleoside antiviral drugs can effectively reduce the recurrence rate of recurrent genital herpes,improve the patient’s quality of life and enhance the body’s *** the possible risk of publication bias,more high-quality randomized controlled trials are still needed to verify the conclusions of this article.

关键词： recurrent genital herpes Chinese herbal medicine nucleoside antiviral drugs meta-analysis

艾司氯胺酮对瑞芬太尼麻醉鼻窦手术患者术后疼痛及苏醒的影响

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广东医学 2024年第4期45卷 458-462页

作者：郑少卿陈小淑邓玉萍黄焕森广州医科大学附属第二医院麻醉科广东广州510220

目的探讨艾司氯胺酮联合麻醉诱导对瑞芬太尼麻醉鼻窦手术患者术后疼痛及苏醒质量的影响。方法择期行鼻内镜鼻窦手术患者90例,ASAⅠ~Ⅱ级,按随机数字表法分为3组,每组30例。分别予瑞芬太尼(R组)、瑞芬太尼+0.25 mg/kg艾司氯胺酮(RA1组)... 详细信息

目的探讨艾司氯胺酮联合麻醉诱导对瑞芬太尼麻醉鼻窦手术患者术后疼痛及苏醒质量的影响。方法择期行鼻内镜鼻窦手术患者90例,ASAⅠ~Ⅱ级,按随机数字表法分为3组,每组30例。分别予瑞芬太尼(R组)、瑞芬太尼+0.25 mg/kg艾司氯胺酮(RA1组)以及瑞芬太尼+0.5 mg/kg艾司氯胺酮(RA2组),3组患者术中持续输注瑞芬太尼、丙泊酚维持麻醉。记录患者的一般情况,术后30 min及1、2、6、12、24 h的VAS评分,麻醉前(T0)和诱导后(T1)的平均动脉压(MAP)和心率(HR),拔管时间、拔管时Ramsay评分,术后24 h内曲马多镇痛例数,以及术后呕吐、头晕、精神症状等不良反应发生率。结果RA1组、RA2组术后30 min及1、2、6 h的VAS评分明显低于R组(P0.05);术后24 h内RA1组及RA2组曲马多镇痛例数减少(P0.05)。结论艾司氯胺酮联合麻醉诱导有利于诱导期循环稳定,减轻麻醉术后疼痛,预防大剂量瑞芬太尼痛觉过敏,不影响术后苏醒,且0.25 mg/kg较0.5 mg/kg患者术后不良反应的发生率低。

关键词：艾司氯胺酮瑞芬太尼鼻内镜鼻窦手术术后痛觉

Acupuncture for obesity and related diseases:Insight for regulating neural circuit

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Journal of Integrative Medicine 2024年第2期22卷 93-101页

作者： Lin-yan Jiang Jun Tian Ya-nan Yang shao-hui Jia qing Shu Department of Rehabilitation Medicine Zhongnan HospitalWuhan UniversityWuhan 430071Hubei ProvinceChina School of Sports Medicine Wuhan Sports UniversityWuhan 430079Hubei ProvinceChina Department of Traditional Chinese Medicine China Resources&Wu Gang General HospitalWuhan 430080Hubei ProvinceChina

Obesity is defined as abnormal or excessive fat accumulation that may impair *** is associated with numerous pathological changes including insulin resistance,fatty liver,hyperlipidemias,and other obesity-related *** comorbidities comprise a significant public health *** anti-obesity drugs have been limited by side effects that include depression,suicidal thoughts,cardiovascular complications and *** treatment has been shown to be effective for treating obesity and obesity-related conditions,while avoiding side ***,the mechanisms of acupuncture in treating obesity-related diseases,especially its effect on neural circuits,are not well understood.A growing body of research has studied acupuncture’s effects on the endocrine system and other mechanisms related to the regulation of neural *** this article,recent research that was relevant to the use of acupuncture to treat obesity and obesity-related diseases through the neuroendocrine system,as well as some neural circuits involved,was *** on this,acupuncture’s potential ability to regulate neural circuits and its mechanisms of action in the endocrine system were reviewed,leading to a deeper mechanistic understanding of acupuncture’s effects and providing insight and direction for future research about obesity.

关键词： Obesity Acupuncture Neural circuit Appetite Energy metabolism

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复合分散药的性能及对FAE燃料分散的影响

含能材料 2006年第4期14卷 244-247,256页

作者：肖绍清厦门爆破工程公司福建厦门361012

设计了一种新型结构的复合分散药,用以取代常规燃料空气炸药(FAE)分散药,对复合分散药爆轰波传播模型、装药结构尺寸、芯药和外层炸药爆速、复合分散药占燃料质量分数对FAE爆炸云雾的形成和传播进行了分析研究。在此基础上,进行了以压... 详细信息

设计了一种新型结构的复合分散药,用以取代常规燃料空气炸药(FAE)分散药,对复合分散药爆轰波传播模型、装药结构尺寸、芯药和外层炸药爆速、复合分散药占燃料质量分数对FAE爆炸云雾的形成和传播进行了分析研究。在此基础上,进行了以压装密度为1.72 ***-3、爆速为8400 m.s-1的8701炸药为芯药,以低密度硝基胍(NQ)为外层炸药,以环氧丙烷(PO)和宏观固态燃料为FAE燃料分散与引爆实验。结果表明,采用复合分散药,分散药燃料比超过1.3%,云雾未发生窜火,云雾形状基本为类草帽形,并可靠爆轰,这说明采取复合装药结构是完全可行的。

关键词：爆炸力学燃料空气炸药(FAE) 复合分散药爆轰波传播方向燃料分散控制

Identification of QTLs associated with cadmium concentration in rice grains

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Journal of Integrative Agriculture 2018年第7期17卷 1563-1573页

作者： HU Da-wei SHENG Zhong-hua LI Qian-long CHEN Wei WEI Xiang-jin XIE Li-hong JIAO Gui-ai shao Gao-neng WANG Jian-long TANG shao-qing HU Pei-song State Key Laboratory of Rice Biology Ministry of Science and Technology/Key Laboratory of Rice Biology and Breeding Ministry of Agriculture/China National Rice Research Institute College of Agronomy Hunan Agricultural University

Cadmium（Cd） contamination in rice has been a hot topic of research because of its potential risk to human health. In this study, a double haploid（DH） population derived from Zhongjiazao 17（YK17）（an early-season indica cultivar）×D50（a tropical japonica cultivar） was used to identify quantitative trait loci（QTLs） associated with Cd concentration in brown rice（CCBR） and Cd concentration in milled rice（CCMR）. Continuous and wide variation for CCBR and CCMR were observed among the DH population. Correlation analysis revealed a positive and highly significant correlation between the two traits. A total of 18 QTLs for CCBR and 14 QTLs for CCMR were identified in five different pot and field trials. Two pairs of QTLs for CCBR（qCCBR2-1 and qCCBR2-2, qCCBR9-1 and qCCBR9-2） and one pair of QTLs for CCMR（qCCMR5-1 and qCCMR5-2） were detected in multiple trials. The alleles increasing CCBR at the qC CBR2-1/qC CBR2-2 and qC CBR9-1/qC CBR9-2 QTLs were contributed by YK17 and D50, respectively, whereas the D50 allele at the qCCMR5-1/qCCMR5-2 QTLs increased CCMR. Eight pairs of QTLs for CCBR and CCMR, qCCBR2-2 and qCCMR2-2, qCCBR3 and qCCMR3, qCCBR4-2 and qCCMR4-1, qCCBR4-3 and qCCMR4-2, qCCBR4-4 and qCCMR4-3, qCCBR5 and qCCMR5-2, qCCBR7 and qCCMR7, and qCCBR11-1 and qCCMR11-2, co-localized on chromosomes 2, 3, 4, 5, 7, and 11, respectively. For all of these QTL pairs, except qCCBR5/qCCMR5-2, the additive effects came from YK17. In addition, four CCMR QTLs showing significant additive×environment interaction and two pairs of CCMR QTLs with bi-allelic epistatic interactions were identified. The results of this study could facilitate marker-assisted selection of breeding rice varieties with low Cd accumulation in grain.

关键词： Cd concentration in grain QTL mapping brown rice milled rice

Simulation of jet-flow solid fraction during spray forming

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International Journal of Minerals,Metallurgy and Materials 2017年第6期24卷 657-669页

作者： Zi-qiang Pi Xin Lu Yuan Wu Lu-ning Wang Cheng-chang Jia Xuan-hui Qu Wei Zheng Li-zhi Wu qing-li shao Institute for Advanced Materials and Technology University of Science and Technology Beijing Beijing 100083 China State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Beijing 100083 China Heye Special Steel Co. Ltd. Shijiazhuang 052165 China

A numerical model was developed to simulate the jet-flow solid fraction of W18Cr4 V high-speed steel during spray forming. The whole model comprises two submodels: one is an individual droplet model, which describes the motion and thermal behaviors of individual droplets on the basis of Newton's laws of motion and the convection heat transfer mechanism; the other is a droplet distribution model, which is used to calculate the droplet size distribution. After being verified, the model was used to analyze the effects of parameters, including the initial gas velocity, deposition distance, superheat degree, and the ratio of gas-to-metal mass flow rates, on the jet-flow solid fraction. Finally, an equation to predict the jet-flow solid fraction directly and conveniently according to the parameters was presented. The values predicted by the equation show good agreement with those calculated by the numerical model.

关键词： modeling steel spray forming solid fraction

Continuous glucose monitoring defined time-in-range is associated with sudomotor dysfunction in type 2 diabetes

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World Journal of Diabetes 2020年第11期11卷 489-500页

作者： qing-Yu Guo Bin Lu Zhan-Hong Guo Zhou-Qin Feng Yan-Yu Yuan Xu-Guang Jin Pu Zang Ping Gu Jia-qing shao Department of Endocrinology Jinling HospitalSchool of MedicineNanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Endocrinology Jinling HospitalNanjing Medical UniversityNanjing 210002Jiangsu ProvinceChina Department of Endocrinology Jinling HospitalSouthern Medical UniversityNanjing 210002Jiangsu ProvinceChina

BACKGROUND Time in range(TIR),as a novel metric for glycemic control,has robust relevance with diabetic *** peripheral neuropathy(DPN)is characterized by sudomotor *** To explore the relationship between TIR obtained from continuous glucose monitoring(CGM)and sudomotor function detected by SUDOSCAN in subjects with type 2 *** The research enrolled 466 inpatients with type 2 *** subjects underwent 3-d CGM and *** was assessed with electrochemical skin conductance in hands(HESC)and feet(FESC).Average feet ESC<60μS was defined as sudomotor dysfunction(+),otherwise it was sudomotor dysfunction(-).TIR refers to the percentage of time when blood glucose is between 3.9-10 mmol/L during 1 d *** Among the enrolled subjects,135(28.97%)presented with sudomotor *** with sudomotor dysfunction(+)showed a decreased level of TIR(P<0.001).Compared to the lowest tertile of TIR,the middle and the highest tertiles of TIR was associated with an obviously lower prevalence of sudomotor dysfunction(20.51%and 21.94%vs 44.52%)(P<0.001).In addition,with the increase of TIR,HESC and FESC increased(P<0.001).Regression analysis demonstrated that TIR was inversely and independently linked with the prevalence of sudomotor dysfunction after adjusting for confounding values(odds ratio=0.979,95%CI:0.971-0.987,P<0.001).CONCLUSION The tight glycemic control assessed by TIR is of vitally protective value for sudomotor dysfunction in type 2 diabetes mellitus.

关键词： Time in range Sudomotor dysfunction SUDOSCAN Diabetic peripheral neuropathy Continuous glucose monitoring Diabetes mellitus Type 2