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The mechanism of the anticancer function of M1 macrophages and their use in the clinic

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Chinese Journal of Cancer 2012年第12期31卷 557-563页

作者： Xing-qing pan College of Pharmacy Ohio State University

M1-type macrophages are capable of inducing lysis in various types of cancer cells, but the mechanism of action is unclear. It has been noted that an "unknown protein" produced together with protease by activated macrophages is responsible for this action. Activated M1 macrophages have been recently reported to produce family 18 chitinases, all of which have been named chitotriosidase. Our experiments have demonstrated that family 18 chitinases work together with proteases and can damage various cancer cells both in vitro and in vivo. Thus, in this article, we suggest that the 50-kDa chitotriosidase is the reported "unknown protein". In addition, we discuss how to properly stimulate activated M1 macrophages to produce 50-kDa chitotriosidases and proteases for destroying cancer cells. Because family 19 chitinase has recently been reported to kill cancer cells, we also discuss the possibility of directly using human family 18 chitotriosidase and the humanized plant family 19 chitinase for cancer treatment.

关键词：巨噬细胞抗癌功能几丁质酶机制蛋白质肿瘤细胞蛋白酶 kDa

Critical review in adsorption kinetic models

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第5期10卷 716-724页

作者： Hui QIU Lu LV Bing-cai pan qing-jian ZHANG Wei-ming ZHANG Quan-xing ZHANG State Key Laboratory of Pollution Control and Resource Reuse Department of Environmental Engineering School of the Environment Nanjing University Nanjing 210093 China

Adsorption is one of the most widely applied techniques for environmental remediation. Its kinetics are of great significance to evaluate the performance of a given adsorbent and gain insight into the underlying mechanisms. There are lots of references available concerning adsorption kinetics, and several mathematic models have been developed to describe adsorption reaction and diffusion processes. However, these models were frequently employed to fit the kinetic data in an unsuitable or improper manner. This is mainly because the boundary conditions of the associated models were, to a considerable extent, ignored for data modeling. Here we reviewed several widely-used adsorption kinetic models and paid more attention to their boundary conditions. We believe that the review is of certain significance and improvement for adsorption kinetic modeling.

关键词： Adsorption kinetics Reaction models Diffusion models Film diffusion Intraparticle diffusion

Synthetic Two-dimensional Organic Structures

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Chinese Journal of Polymer Science 2018年第4期36卷 425-425,426-444页

作者： Hui Liu Xiao-Nan Kan Chen-Yu Wu qing-Yan pan Zhi-Bo Li Ying-Jie Zhao qingdao University of Science and Technology Qingdao 266042China Centre for Advanced Macromolecular Design School of Chemical EngineeringThe University of New South WalesSydneyNSW2052Australia

Synthetic two-dimensional（2 D） polymers have totally different topology structures compared with traditional linear or branched polymers. The peculiar 2 D structures bring superior properties. Although, from linear to 2 D polymers, the study of these new materials is still in its infancy, they already show potential applications especially in optoelectronics, membranes, energy storage and catalysis, etc. In this review, we summarize the recent progress of the 2 D materials from three respects：（1） Chemistry—different types of polymerization reactions or supramolecular assembly to construct the 2 D networks were described;（2） Preparation methods—surface science, crystal engineering approaches and solution synthesis were introduced;（3） Functionalization and some early applications.

关键词： Two-dimensional structures Interracial synthesis 2D crystal Covalent organic frameworks (COFs) Supramolecular assembly

Martensitic transformation and magnetic properties in Mn_(49-x)Cu_(x)Ni_(41)Sn_(10)(x=0-2)

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Rare Metals 2023年第7期42卷 2433-2438页

作者： Meng-Zhe Zhao Hong-Mei Qiu Ze-Ya Zhu Yun-Li Xu Zhu-Hong Liu Li-qing pan Department of Applied Physics University of Science and Technology BeijingBeijing100083China College of Science China Three Gorges UniversityYichang443002China

The crystal structure,phase transition,metamagnetic behavior and magnetic entropy change(ΔS_(M))of the Mn_(49-x)Cu_(x)Ni_(41)Sn_(10)(x=0-2)alloys were systematically *** results of experiment about crystal structure confirm that Mr_(49-x)Cu_(x)Ni_(41)Sn_(10)alloys have a highly ordered cubic L2_(1)Heusler *** Cu element improving,all samples have a martensitic transformation and inverse martensitic transformation by analyzing the result of magnetic *** saturation magnetization of samples decreases gradually,the martensitic transformation temperature(T_(M))of as-annealed samples increases to a high-temperature area,and the Curie temperature(T_(C))of samples moves to a low-temperature area with the content of Cu element increasing from x=0 to x=*** positive values of magnetic entropy change(ΔS_(M))of all alloys were investigated near the martensitic *** the applied magnetic field is 3 T,a worthwhile value ofΔS_(M)can reach up to 32.0 J·kg^(-1)·K^(-1)in Mn_(47)Cu_(2)Ni_(41)Sn_(10)alloy.

关键词： Heusler alloys Arc melting X-ray diffraction Magnetic properties

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满足G^1边界条件的混合细分曲面设计

计算机辅助设计与图形学学报 2014年第6期26卷 956-962页

作者：潘青湖南师范大学数学与计算机科学学院高性能计算与随机信息处理省部共建教育部重点实验室长沙410081

自由曲面设计从工业制造到建筑设计都有着广泛的应用.文中将细分算法与几何偏微分方程方法相结合,构建一种统一的自由曲面设计方法.该方法将曲面扩散流作为演化方程,曲面的控制网格是三角形和四边形混合型网格;数值模拟采用Loop和Catmul... 详细信息

自由曲面设计从工业制造到建筑设计都有着广泛的应用.文中将细分算法与几何偏微分方程方法相结合,构建一种统一的自由曲面设计方法.该方法将曲面扩散流作为演化方程,曲面的控制网格是三角形和四边形混合型网格;数值模拟采用Loop和Catmull-Clark混合细分的有限元方法,通过方程演化得到混合细分曲面的控制网格.数值实验结果表明,文中方法能构造高质量的曲面.此研究呈现出一种新颖的构造几何偏微分方程细分曲面的技术.

关键词：自由曲面设计细分算法曲面扩散流 G1边界条件

Investigation of plasmonic whispering gallery modes of graphene equilateral triangle nanocavities

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Science China(Information Sciences) 2016年第4期59卷 172-180页

作者： Yixin HUANG Weibin QIU Shangxin LIN Jing ZHAO Houbo CHEN Jia-Xian WANG Qiang KAN Jiao-qing pan College of Information Science and Engineering Huaqiao University Institute of Semiconductors Chinese Academy of Sciences

In this paper, a graphene-based equilateral triangle nanocavity is proposed and numerically investigated. The relationship between the mode characteristics and the nanocavity parameters, such as the geometry of nanocavity and the chemical potential of graphene, is systematically explored. A high-order plasmonic WGM(whispering gallery mode) with a high quality factor of 147.93 is obtained in our nanocavity with a wavelength of around 1.415 μm in free space, with a corresponding Purcell factor as high as 7.067×108. The proposed plasmonic WGM nanocavity could be a key component of the high density plasmonic integrated circuits due to its ultra-compactness and performances.

关键词： graphene nanocavity resonator surface plasmonic polaritons whispering gallery mode plasmonic integrated circuits

Preparation of magnetic anion exchange resin and their adsorption kinetic behavior of reactive blue

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Chinese Chemical Letters 2011年第9期22卷 1091-1094页

作者： Chen Dong Shuang Feng Yang Fei pan qing Zhou Wei Ben Yang Ai Min Li State Key Laboratory of Pollution Control and Resources Reuse School of the Environment Nanjing University Nanjing 210093 China

Magnetic anion exchange resin （MD-1） was prepared from quaternization of magnetic copolymeric resin （glycidyl methacry- late-co-divinylbenzene）. For comparison, magnetic resin MD-0 without quaternization and non-magnetic resin （D-l） were also synthesized for the adsorption process. It was found that the adsorption was mainly contributed to the chemical interaction between quaternary ammonium groups and reactive blue RXHC. Due to the smaller size, MD- 1 had faster adsorption and desorption kinetics than D-1. Coupled with the advantage of easy separation, the magnetic anion exchange resin was considered to be superior to common anion exchange resin in removal of reactive dye.

关键词： Magnetic resin Glycidyl methacrylate Reactive blue RXHC Anion exchange Adsorption kinetics

Softev: UML-Based PSEE Environment

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Wuhan University Journal of Natural Sciences 2001年第Z1期6卷 524-530页

作者： pan Qiu ling, Liu Zong tian, Jia Liang, Xiu qing,pan Biao Research Institute of Microcomputer, Hefei University of Technology, Hefei 230009, China Research Institute of Microcomputer Hefei University of Technology Hefei 230009 China

Software development processes, as a mean to ensure software quality and productivity, have been widely accepted within the software development community. This research introduces how to assist developers to establish quality management plan and monitor the implementation of software processes quantitatively in a CASE environment. A PSEE (process centered software engineering environment) named Softev has been brought forward to provide developers the environment to define, execute and monitor their processes. As UML is becoming a standard diagrammatic notation for object oriented modeling and is spreading rapidly, it has been chosen to express the artifacts developed during the requirement analysis and system design stages. In the early products of software process engineering, most research mainly focus on the representations of complex organizational processes and architectures for process centered application support environment. However, the metrics of software processes and artifacts was not paid sufficient attention to. This research proposes the attributes to be measured during the development period which enable managers to predict and supervise the software project more precisely.

关键词： software process quality control UML metrics

Rheological　Characteristics　of　Domestic　Honeys

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农业工程学报 1996年第2期 146-150页

作者： Chen qing chun ① pan Jun zheng (Nanjing Agricultural University,Nanjing)

采用流变学方法对国产蜂蜜流变特性进行了研究。流变试验数据分析表明国产蜂蜜流变模型为Ｎｅｗｔｏｎ体，而非过去所认为的Ｂｉｎｇｈａｍ体。影响国产蜂蜜粘度的诸因素中，水分的影响最为显著。建立了国产蜂蜜ｗ－ｔ－η图，以充分描... 详细信息

采用流变学方法对国产蜂蜜流变特性进行了研究。流变试验数据分析表明国产蜂蜜流变模型为Ｎｅｗｔｏｎ体，而非过去所认为的Ｂｉｎｇｈａｍ体。影响国产蜂蜜粘度的诸因素中，水分的影响最为显著。建立了国产蜂蜜ｗ－ｔ－η图，以充分描述其水分、温度与粘度之间的各种关系

关键词：蜂蜜流变模型水分-温度-粘度图