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Coupled effects of pH and kaolinite colloids on antibiotic transport in porous media

Pedosphere 2023年第5期33卷 788-799页

作者： Shuhua JI Xiaowen LIU Xiu MENG Shaohui XU qing lin Department of Environmental Science and Engineering Qingdao UniversityQingdao 266071China

Antibiotics can interact with natural colloids and the surrounding media upon entry into soil and groundwater systems,which significantly alters their dynamic behavior and complicates our understanding of antibiotic fate and transport in porous *** this study,co-transport of antibiotics and kaolinite colloids was systematically investigated using combined column experiments and numerical simulation under different pH ***(SDZ)transport was enhanced by kaolinite colloids under neutral and alkaline conditions,which was attributed to the higher mobility of colloids as SDZ carriers,as well as competitive ***,most injected SDZ was transported in a dissolved form owing to the low sorption capacity of SDZ to kaolinite colloids and quartz *** colloid-facilitated transport model provided a good description of total SDZ transport,but underestimated colloidal SDZ transport using parameters from kinetic sorption *** colloids significantly promoted ciprofloxacin(CIP)transport at pH 4.0,but inhibited it at pH 7.0 ***,enhanced CIP transport was due to the decreased number of effective sorption sites on quartz sand and the increased desorption of CIP from kaolinite *** neutral and alkaline conditions,deposited colloids provided additional sorption sites for CIP,which contributed to CIP ***,CIP significantly inhibited the transport of kaolinite colloids owing to the increases in colloidal aggregate size and zeta ***,our results highlighted the different effects of mobile and immobile colloids on antibiotic transport,in addition to the implications of antibiotic speciation and clay colloids when predicting the transport behavior of these compounds.

关键词： aadvection-dispersion equation ciprofloxacin colloid-facilitated transport model numerical simulation sulfadiazine two-site model

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Twin model-based fault detection and tolerance approach for in-core self-powered neutron detectors

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Nuclear Science and Techniques 2023年第8期34卷 86-99页

作者： Jing Chen Yan-Zhen Lu Hao Jiang Wei-qing lin Yong Xu College of Electrical Engineering and Automation Fuzhou UniversityFuzhou 350108China The Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China Fujian Fuqing Nuclear Power Co. Ltd.Fujian 350318China

The in-core self-powered neutron detector(SPND)acts as a key measuring device for the monitoring of parameters and evaluation of the operating conditions of nuclear *** detection and tolerance of faulty SPNDs are indispensable for reliable reactor *** completely extract the correlated state information of SPNDs,we constructed a twin model based on a generalized regression neural network(GRNN)that represents the common relationships among overall *** SPNDs were determined because of the functional concordance of the twin model and real monitoring sys-tems,which calculated the error probability distribution between the model outputs and real *** detection follows a tolerance phase to reinforce the stability of the twin model in the case of massive failures.A weighted K-nearest neighbor model was employed to reasonably reconstruct the values of the faulty signals and guarantee data *** experimental evaluation of the proposed method showed promising results,with excellent output consistency and high detection accuracy for both single-and multiple-point faulty *** unexpected excessive failures,the proposed tolerance approach can efficiently repair fault behaviors and enhance the prediction performance of the twin model.

关键词： Self-powered neutron detector Twin model Fault detection Fault tolerance Generalized regression neural network Nuclear power plant

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Two-stage cyclic ammonium sulfate roasting and leaching of extracting vanadium and titanium from vanadium slag

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Chinese Journal of Chemical Engineering 2022年第7期35卷 39-47页

作者： qing lin Guoquan Zhang Kun Wang Dongmei Luo Siyang Tang Hairong Yue School of Chemical Engineering Sichuan UniversityChengdu 610065China

Compared with traditional sodium or calcification roasting process for vanadium extraction from raw vanadium slag(V-slag),ammonium sulfate(AS)roasting could reduce about 470℃ roasting temperature and avoid Cl_(2),HCl,sodium-containing waste-water and waste gypsum *** reduce the amount of AS added in vanadium extraction process,an efficient AS two-stage cyclic roasting and acid leaching process was *** result of TG analysis indicates V-slag could be decomposed in 275-380℃ using AS roasting *** 2.03:1 total mass ratio of AS to V-slag,90.86%V and 80.54%Ti could be extracted after 380℃ roasting for 30 min and 8%initial concentration of H_(2)SO_(4) leaching at 70℃ for 100 *** analysis indicates V-containing spinel phase in the 1st stage leaching residue would be efficiently decomposed by the cyclic two-stage roasting and leaching ***,the valence of V(Ⅲ)in raw V-slag was not changed after the 1st AS roasting stage,but a part of V(Ⅲ)in the 1st leaching residue was oxidized to V(V)after 2nd roasting process.

关键词： Vanadium Titanium Roasting Leaching

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Contributions of aversive environmental stress to migraine chronification:Research update of migraine pathophysiology

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World Journal of Clinical Cases 2021年第9期9卷 2136-2145页

作者： Tang-Hua Liu Zhen Wang Fang Xie Yan-qing Liu qing lin Department of Algology The Third People's Hospital of YibinYibin 644000Sichuan ProvinceChina Department of Psychology University of Texas at ArlingtonArlingtonTX 76019United States Department of Algology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China

Clinical studies have suggested that internal and/or external aversive cues may produce a negative affective-motivational component whereby maladaptive responses(plasticity)of dural afferent neurons are initiated contributing to migraine ***,pathophysiological processes and neural circuitry involved in aversion(unpleasantness)-producing migraine chronification are still *** interdisciplinary team conducted this narrative review aimed at reviewing neuronal plasticity for developing migraine chronicity and its relevant neurocircuits and providing the most cutting-edge information on neuronal mechanisms involved in the processing of affective aspects of pain and the role of unpleasantness evoked by internal and/or external cues in facilitating the chronification process of migraine ***,information presented in this review promotes the understanding of the pathophysiology of chronic migraine and contribution of unpleasantness(aversion)to migraine *** hope that it will bring clinicians’attention to how the maladaptive neuroplasticity of the emotion brain in the aversive environment produces a significant impact on the chronification of migraine headache,which will in turn lead to new therapeutic strategies for this type of pain.

关键词： Migraine chronification Aversive environmental stress Migraine pathophysiology Migraine headache Roles of unpleasantness Emotion brain

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A POTENTIAL MECHANISM OF BREAKTHROUGH BLEEDING ASSOCIATED WITH PROGESTIN:INVOLVEMENT IN ALTERATION OF ENDOMETRIAL ENDOTHELIAL CELLS

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Chinese Medical Sciences Journal 2008年第1期23卷 32-37页

作者： Gui-hua Sha Shou-qing lin Department of Obstetrics and Gynecology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730

Objective To explore the potential mechanism of breakthrough bleeding associated with progestin with in vitro *** The isolation and culture of human endometrial endothelial cells(HEECs)was performed with the method established in our *** content and activity of urokinase-type plasminogen activator(uPA)and the content of plasminogen activator inhibitor-1(PAI-1)in cell supernatants after incubated with different concentrations of progesterone(0-5 μmol/L)and 17β-estradiol(0,0.1,or 1 nmol/L)were measured by method of *** rate of HEECs was measured by flow *** cell count was measured by *** The increased level of progesterone(0.5-5 μmol/L)combined with 17β-estradiol elevated content and activity of uPA while the production of PAI-1 remained *** apoptosis of HEECs was inhibited along with the increment of total viable cell counts at higher concentrations of progesterone with 17β-*** The inhibition of apoptosis and increased content and activity of uPA may contribute to the occurrence of irregular bleeding associated with progestin use to some extent.

关键词： progesterone 17β-estradiol breakthrough bleeding apoptosis urokinase-type plasminogen activator

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Existence and Uniqueness of Solutions to Random Impulsive Differential Systems

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Acta Mathematicae Applicatae Sinica 2006年第4期22卷 627-632页

作者： Shu-jin Wu Xiao-lin Guo Song-qing lin Department of Statistics East China Normal University Shanghai 200062 China Faculty of Information Technology Aihui University of Finance and Trade Bengbu 233041 China

The existence and uniqueness in mean square of solutions to certain random impulsive differential systems is discussed in this paper. Cauchy-Schwarz inequality, Lipschtiz condition and techniques in stochastic analysi... 详细信息

关键词： Random impulsive differential system, existence, uniqueness boundedness

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Humidity Effects on Conductivity of DNA Molecules

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Communications in Theoretical Physics 2006年第2X期46卷 381-384页

作者： YAN Xun-ling DONG Rui-Xin lin qing-De School of Physical Science and Information Engineering Liaocheng University Liaocheng 252059 China College of Radiology Taishan Medical University Taian 271000 China

We present a model related to the humidity to describe the conductivity of homogeneous DNA molecule, where the hydration of phosphate group and bases are taken into account. The calculated results show the oscillation feature of dI/dV-V curves and the semiconductor behavior of DNA. With the relative humidity increasing, the voltage gap becomes narrow and the maximum of conductance increases nonlinearly. The conductivity of DNA approaches to stabilization when the relative humidity reaches a certain value. These results are in agreement with experimental measurements.

关键词： DNA conductivity humidity

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Fast Computation of Sparse Data Cubes with Constraints

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Wuhan University Journal of Natural Sciences 2004年第2期9卷 167-172页

作者： FengYu-cai ChenChang-qing FengJian-lin XiangLong-gang SchoolofComputerScienceandTechnology HuazhongUniversityofScienceandTechnologyWuhan430074HubeiChina

For a data cube there are always constraints between dimensions or among attributes in a dimension, such as functional dependencies. We introduce the problem that when there are functional dependencies, how to use them to speed up the computation of sparse data cubes. A new algorithm CFD (Computation by Functional Dependencies) is presented to satisfy this demand. CFD determines the order of dimensions by considering cardinalities of dimensions and functional dependencies between dimensions together, thus reduce the number of partitions for such dimensions. CFD also combines partitioning from bottom to up and aggregate computation from top to bottom to speed up the computation further. CFD can efficiently compute a data cube with hierarchies in a dimension from the smallest granularity to the coarsest one. Key words sparse data cube - functional dependency - dimension - partition - CFD CLC number TP 311 Foundation item: Supported by the E-Government Project of the Ministry of Science and Technology of China (2001BA110B01)Biography: Feng Yu-cai (1945-), male, Professor, research direction: database system.

关键词： sparse data cube functional dependency dimension partition CFD

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支架外固定与钢板内固定治疗桡骨远端粉碎性骨折的Meta分析

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中国组织工程研究 2025年第21期29卷 4602-4611页

作者：林晴刘峘成永忠姜俊杰李永耀李光耀北京中医药大学北京市100020 中国中医科学院中医临床基础医学研究所北京市100010 中国中医科学院望京医院创伤一科北京市100020

目的:外固定支架和钢板内固定作为桡骨远端粉碎性骨折的常用治疗方法,在临床上各有利弊。系统评价外固定支架与钢板内固定治疗粉碎性桡骨远端骨折的临床疗效及安全性,为桡骨远端骨折中西医结合诊疗指南研制提供论证依据。方法:系统检索P... 详细信息

目的:外固定支架和钢板内固定作为桡骨远端粉碎性骨折的常用治疗方法,在临床上各有利弊。系统评价外固定支架与钢板内固定治疗粉碎性桡骨远端骨折的临床疗效及安全性,为桡骨远端骨折中西医结合诊疗指南研制提供论证依据。方法:系统检索PubMed、Web of Science、Embase、Cochrane Library、中国知网、中国生物医学文献数据库、维普和万方数据库,纳入2013年10月至2023年10月发表的关于外固定支架和钢板内固定治疗粉碎性桡骨远端骨折的随机对照试验文献,按照纳入标准和排除标准筛选文献,使用Review Manager进行文献质量评价和Meta分析。结果:(1)纳入8篇文献,其中中文文献4篇,英文文献4篇、总样本量648例,外固定支架组328例,钢板内固定组320例;(2)术后3个月,钢板内固定组的背伸、掌屈、旋后范围优于外固定支架组;术后12个月,钢板内固定组的握力、掌倾角、掌屈、旋前和旋后范围优于外固定支架组;钢板内固定组在术后感染方面优于外固定支架组,其余结局指标两组差异均无显著性意义。结论:现有8项证据表明,在粉碎性桡骨远端骨折的治疗方式选择上,外固定支架与切开钢板内固定都有良好的治疗效果,综合其他因素钢板内固定更胜一筹,但是对于一些高度严重的粉碎性桡骨远端骨折、骨质较差、严重污染的开放性骨折以及软组织肿胀而无法进行切开手术的特殊患者,外固定支架才是首选。此次研究结果具有局限性,未来还需要开展更多高质量、大样本、多中心的随机对照试验研究,另外需重视远期疗效、其他次要指标的观察,补充优化当前研究结果。

关键词：粉碎性桡骨远端骨折外固定支架内固定临床疗效安全性荟萃分析

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Correlation of Photosensitization and Binding Mode of Methylene Blue and DNA

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Chinese Physics Letters 2011年第1期28卷 115-118页

作者： LIU Tao ZHANG Feng CHEN Ping TANG Guo-qing lin Lie Key Laboratory of Optoelectronic Information Science and Technology (Ministry of Education) Institute of Modern Optics Nankai University Tianjin 300071

Binding of methylene blue （MB） and DNA, photosensitization of MB in DNA, and correlation of photosensiti- zation and binding mode are studied at different concentration ratios of DNA and MB. The absorption spectra indicate that the electrostatic binding is the main mode at low γ ratios （γ≤ 2）, while at high γ ratios （γ 〉 2） the intercalative binding is dominated. Mudies on dynamics of photosensitization formation of singlet oxygen （102） for MB in DNA are carried out by using＂ time-resolved technology. There are no obvious changes of the singlet oxygen lifetime and the triplet state MB molecule （MB3＋＊） lifetime at low ratios, they are about 4 μs and 1 μs, respectively. However, we could not obtain the 1 O2 lifetime and MB3＋＊ lifetime due to the great decrease of 1 O2 phosphorescence signals at high ratios. These results show that the photosensitization and binding mode of MB in DNA possess high correlation. When MB binds with DNA by electrostatic interaction, type-lI photosen- sitization of MB plays a major role in photodynamic effect, the damage of DNA probably could be ascribed to 1 O2. However, at high ratios, binding mode between MB and DNA turns to intercalative binding, which greatly weakens the type-Ⅱ photosensitization process. Charge transfer between MB and DNA possibly becomes the main damage mechanism.

关键词： Instrumentation and measurement Medical physics Biological physics

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