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蛋白CXCR7的发现及其作用

中华病理学杂志 2009年第5期38卷 358-360页

作者：沈勤王芳云南省昆明医学院病理学教研室 650031

CXCR7，以前称为RDC1，1989年从狗甲状腺cDNA库筛选出来的，最初报道是一个具有血管活性肠肽（VIP）的受体，接着被确定为与降钙素基因相关肽结合的受体，后来又认为与肾上腺髓质素结合，然而这些定论最终都被否决了。事实上，RDC1与已... 详细信息

CXCR7，以前称为RDC1，1989年从狗甲状腺cDNA库筛选出来的，最初报道是一个具有血管活性肠肽（VIP）的受体，接着被确定为与降钙素基因相关肽结合的受体，后来又认为与肾上腺髓质素结合，然而这些定论最终都被否决了。事实上，RDC1与已知的一些趋化因子受体有高度相似序列，故属于G蛋白耦联受体（G-protein coupled receptor，GPCR）的亚族。然而因为不知道或者认为没有配体故一直将RDC1归类为孤儿GPCR。最近研究提出RDC1与CXCR4分享配体基质细胞衍生因子1／趋化因子配体12（SDF1／CXCL12），

关键词： G蛋白耦联受体趋化因子受体趋化因子配体基质细胞衍生因子1 降钙素基因相关肽 receptor 血管活性肠肽肾上腺髓质素

Customer Value Analysis in the Context of Internet Commerce of Industrial Robots

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International Journal of Plant Engineering and Management 2015年第1期20卷 1-12页

作者： ZHANG Xin-wei TONG Shu-rong wang Ke-qin Institute of Design Management Northwestern Polytechnical University

Internet commerce of industrial robots has the potential to provide higher value to customers in downstream industries. Aiming to transform the potential to a reality, customer values are systematically analyzed on basis of Value-Focused Thinking, which includes five aspects of identification, expression, organization, measurement and utilization. Nine types of heuristic questions are firstly used to identify customers＇ value statements. These statements are then transformed into a common expression. Then means-ends analysis and part- whole analysis are used to infer the relationships among statements, and result in a means-ends network and a hierarchical value tree for organizing them. To measure achievement of customer values, a decision model is used to identify and select the measurable attribute of each value statement, and a value model is then constructed from the set of measurable attributes. Finally, customer values are actively applied to support decision customer procurement, website design, creative or improved design of industrial robots. making of

关键词： customer values value-focused thinking industrial robots internet commerce value model

Picosecond terahertz pump-probe realized from Chinese terahertz free-electron laser

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Chinese Physics B 2020年第8期29卷 127-132页

作者： hao wang Wen Xu Hong-Ying Mei Hua qin Xin-Nian Zhao Hua Wen Chao Zhang Lan Ding Yong Xu Peng Li Dai Wu Ming Li Key Laboratory of Materials Physics Institute of Solid State PhysicsChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China School of Physics and Astronomy and Yunnan Key Laboratory for Quantum Information Yunnan UniversityKunming 650091China Faculty of Information Engineering Huanghuai UniversityZhumadian 463000China Key Laboratory of Nanodevices and Applications Suzhou Institute of Nano-tech and Nano-bionicsChinese Academy of SciencesSuzhou 215123China Institute of Applied Electronics Chinese Academy of Engineering PhysicsMianyang 621900China

Electron energy relaxation timeτis one of the key physical parameters for electronic *** this study,we develop a new technique to measureτin a semiconductor via monochrome picosecond(ps)terahertz(THz)pump and probe *** special THz pulse structure of Chinese THz free-electron laser(CTFEL)is utilized to realize such a technique,which can be applied to the investigation into THz dynamics of electronic and optoelectronic materials and *** measure the THz dynamical electronic properties of high-mobility n-GaSb wafer at 1.2 THz,1.6 THz,and 2.4 THz at room temperature and in free *** obtained electron energy relaxation time for n-GaSb is in line with that measured via,e.g.,four-wave mixing *** major advantages of monochrome ps THz pump-probe in the study of electronic and optoelectronic materials are discussed in comparison with other ultrafast optoelectronic *** work is relevant to the application of pulsed THz free-electron lasers and also to the development of advanced ultrafast measurement technique for the investigation of dynamical properties of electronic and optoelectronic materials.

关键词： free-electron laser ultrafast measurements picosecond phenomena

A weak allele of TGW5 enables greater seed propagation and efficient size-based seed sorting for hybrid rice production

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Plant Communications 2024年第4期5卷 137-140页

作者： Jiezheng Ying Yaobing qin Fengyong Zhang Liu Duan Peng Cheng Man Yin Yifeng wang Xiaohong Tong Jie Huang Zhiyong Li Xianjun Song Jian Zhang State Key Lab of Rice Biology and Breeding China National Rice Research InstituteHangzhou 311400China State Key Laboratory of Biocatalysis and Enzyme Engineering School of Life SciencesHubei UniversityWuhan 430062China Key Laboratory of Plant Molecular Physiology Institute of Botanythe Chinese Academy of SciencesBeijing 100093China These authors contributed equally to this article

Dear Editors,Heterosis utilization is an effective way to improve crop *** rice typically out-yield inbred rice varieties by 10%and show better stress resistance,and they have been widely adopted in Asian countries since the 1980s(Cheng et al.,2007).To produce rice F1 hybrid seeds(HSDs),male sterile lines(MSLs)are grown side by side with restorer lines(RLs)in order to receive the RL *** seed production system faces challenges in maintaining the seed purity of the HSDs owing to the physical proximity of MSL and RL plants in the ***,MSLs and RLs are planted in alternate rows to enable physical separation of seeds during harvesting.

关键词： planted sterile enable

Next-generation sequencing confirmed the diagnosis of isolated central nervous system infection caused by Talaromyces marneffei in an immunocompetent patient

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Chinese Medical Journal 2020年第3期133卷 374-376页

作者： Dong-Mei wang Hong-Ling Ma Miao-qin Tan Yong-Ming Wu Sheng-Nan wang Department of Neurology Nanfa叩HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China Department of Neurology Liaocheng People's HospitalLiaochengShandong 252000China.

To the Editor:Talaromyces marneffei(***) formerly known as Penicillium marneffei、was first isolated from the liver of a wild Chinese bamboo rat in Vietnam by Capponi et al in the Pasteur Inst让ute in *** et al reported the first case of human natural infection in *** patient was a human immunodeficiency virus(HIV)-negative American missionary with Hodgkin *** main epidemic areas of the disease are Southeast Asia,including Thailand,Vietnam,and *** and Guangxi are the most common areas in China.11厅.marneffei is a conditional pathogenic fungus mostly found in people with low immunity to infections;HIV-positive patients are the most commonly affected.

关键词： diagnosis immunity mostly

Comparison of DNA methylation in developing seeds of yellow-and black-seeded Brassica napus by MSAP

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Comparison of DNA methylation in developing seeds of yellow-...

WAVELET TRANSFORM ASSOCIATED TO THE AFFINE GROUP AGS,

2016年全国植物生物学大会

作者： Yue wang Xia qin wang Jinjin Jiang Youping wang Jiangsu Provincial Key Laboratory of Crop Genetics and Physiology Yangzhou University

DNA methylation is a crucial modification process implicated in epigenetic regulation of gene expression,which may be responsible for variation of agronomic traits. However,the epigenetic regulation of yellow-and black-seeded character in Brassica napus has not been reported. In this study,methylation-sensitive amplification polymorphism(MSAP) analysis was performed to investigate target regions of seed coat variation in B. napus by using yellow-seeded rapeseed line derived from the somatic hybrids of B. napus-Sinapis alba and black-seeded rapeseed as materials. Extensive methylation changes were observed between yellow-and black-seeded B. napus. In particular,0% of demethylation and % of hypermethylation were detected in yellow rapeseeds compared with black seeds. Nonetheless,this variation was barely identified among different developing stages. Relative expression value and 20 polymorphic fragments in MSAP profiles were analyzed. The gene expression of demethylated fragments in yellow rapeseeds was upregulated. F or instance,b HLH,a transcription factor regulating flavonoid biosynthesis,was upregulated at three to five weeks after flowers(WAF) of yellow seeds. In general,epigenetic changes among rapeseed lines with different seed colors likely helped elucidate the formation of yellow seed character.

关键词： Brassica napus yellow seed DNA methylation flavonoid biosynthesis

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Analysis in Theory and Applications 1995年第4期11卷 45-50页

作者： Qianqing qin & Nengchao wang (Huazhong University of Science and Technology, China)

This paper considers wavelet transforms associated to the affine group, which is more general than the paper given by R. Murenzi, and it seems more important in mathematical theory and more natural to be used to analy... 详细信息

关键词： WAVELET TRANSFORM ASSOCIATED TO THE AFFINE GROUP AGS more Morlet than

Improvement in Structural and Magnetic Properties of Electrospun Ni1-xCuxFe2O4Nanofibers

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Soft Nanoscience Letters 2017年第2期7卷 17-26页

作者： Weiwei Pan Xinlei Zhang qin-Fang Liu Jianbo wang School of Physics and Electronic Science Guizhou Normal College Guiyang China Institute of Applied Magnetics Key Laboratory of Magnetism and Magnetic Materials of Ministry of Education Lanzhou University Lanzhou China

A series of Ni1-xCuxFe2O4 (0.0 ≤ x ≤ 1.0) nanofibers have been synthesized employing electrospinning method at 650°C. The effect of Cu substitution on structural, morphology and magnetic properties of NiFe2O4 nanofibers is reported. The XRD analysis showed the formation of single-phase cubic spinel Ni-Cu ferrite and an increasing behavior of lattice constant. The surface morphology is characterized by SEM, it is investigated that nanofibers have uniform and continuous morphology. The VSM results showed Cu substitution played an important role in magnetic properties of Ni1-xCuxFe2O4. The saturation magnetization (Ms) decreases linearly with increasing Cu2+ content, while coercivity (Hc) has slowly decreased before x ≤ 0.5, and then sharply increased to 723.9 Oe for x = 1.0. The magnetic properties of Ni1-xCuxFe2O4 can be explained in Neel’s model, cation distribution and shape anisotropy.

关键词： NiCu Ferrite Electrospinning Magnetic Properties Nanostructures

Exploring age and gender disparities in cardiometabolic phenotypes and lipidomic signatures among Chinese adults: a nationwide cohort study

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Life Metabolism 2024年第5期3卷 61-74页

作者： Xiaojing Jia Hong Lin Ruizhi Zheng Shuangyuan wang Yilan Ding Chunyan Hu Mian Li Yu Xu Min Xu Guixia wang Lulu Chen Tianshu Zeng Ruying Hu Zhen Ye Lixin Shi qing Su Yuhong Chen Xuefeng Yu Li Yan Tiange wang Zhiyun Zhao Guijun qin qin Wan Gang Chen meng Dai Di Zhang Bihan Qiu Xiaoyan Zhu Jie Zheng Xulei Tang Zhengnan Gao Feixia Shen Xuejiang Gu Zuojie Luo Yingfen qin Li Chen Xinguo Hou Yanan Huo Qiang Li Yinfei Zhang Chao Liu Youmin wang Shengli Wu Tao Yang Huacong Deng Jiajun Zhao Yiming Mu Shenghan Lai Donghui Li Weiguo Hu Guang Ning Weiqing wang Yufang Bi Jieli Lu for theC Study Group Department of Endocrine and Metabolic Diseases Shanghai Institute of Endocrine and Metabolic DiseasesRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai National Clinical Research Center for Endocrine and Metabolic Diseases Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the People's Republic of ChinaShanghai National Center for Translational MedicineRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Endocrine and Metabolic Diseases The First Hospital of Jilin UniversityChangchunJilin 130021China Department of Endocrine and Metabolic Diseases Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Zhejiang Provincial Center for Disease Control and Prevention HangzhouZhejiang 310051China Department of Endocrine and Metabolic Diseases Affiliated Hospital of Guiyang Medical CollegeGuiyangGuizhou 550004China Department of Endocrine and Metabolic Diseases Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Endocrine and Metabolic Diseases Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China Department of Endocrine and Metabolic Diseases Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdong 510120China Department of Endocrine and Metabolic Diseases The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Endocrine and Metabolic Diseases The Affiliated Hospital of Southwest Medical UniversityLuzhouSichuan 646000China Department of Endocrine and Metabolic Diseases Fujian Provincial HospitalFujian Medical UniversityFuzhouFujian 350003China Department of Endocrine and Metabolic Diseases The First Hospital of Lanzhou UniversityLanzhouGansu 730000China Department of Endocrine and Metabolic Diseases Dalian Municipal Central HospitalDalianLiao

Understanding sex disparities in modifiable risk factors across the lifespan is essential for crafting individualized intervention *** aim to investigate age-related sex disparity in cardiometabolic phenotypes in a large nationwide Chinese cohort.A total of 254,670 adults aged 40 years or older were selected from a population-based cohort in *** sex disparities in the prevalence of metabolic diseases were observed across different age strata,particularly for dyslipidemia and its com*** additive models were employed to characterize phenotype features,elucidating how gender differences evolve with advancing *** of the 16 phenotypes consistently exhibited no sex differences,while four(high-density lipoprotein[HDL]cholesterol,apolipoprotein A1,diastolic blood pressure,and fasting insulin)displayed significant sex differences across all age ***,apolipoprotein B,non-HDL cholesterol,and total cholesterol demonstrated significant age-dependent sex dis***,premenopausal females exhibited significant age-related differences in lipid levels around the age of 40-50 years,contrasting with the relatively stable associations observed in males and postmenopausal *** played an important but not sole role in age-related sex differences in blood *** duration also had an age-and sex-dependent impact on *** analysis and K-means clustering further revealed that 58.6%of the 263 measured lipids varied with sex and age,with sphingomyelins,cholesteryl esters,and triacylglycerols being the most profoundly influenced lipid species by the combined effects of age,sex,and their *** findings underscore the importance of age consideration when addressing gender disparities in metabolic diseases and advocate for personalized,age-specific prevention and management.

关键词： sex difference aging metabolic diseases modifiable risk factors lipidomics