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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay shou-shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov serge Bondarenko stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin chen Danping chen Fuqing chen Fusan chen Gang chen guoming chen hua-xing chen Huirun chen Jinhui chen Ji-Yuan chen Kai chen Mali chen mingjun chen mingshui chen Ning chen shanhong chen shanzhen chen shao-Long chen shaomin chen shiqiang chen Tianlu chen Wei chen xiang chen xiaoyu chen xin chen Xun chen Xurong chen Ye chen Ying chen Yukai chen Zelin chen Zilin chen Gang chen Boping chen Chunhui chen Hok Chuen cheng huajie cheng shan cheng tongguang cheng Yunlong chi Pietro chimenti Wen Han chiu Guk Cho ming-Chung Chu xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun Dai xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori chiara De sio Elisa Del Core shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central south university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa chengdu Kaitengsifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geosciences Beijing china university of Geosciences WuhanHubei china university of mining and Technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRs/INP) Marseille Dalian minzu university DalianLiaoning Dalian university of Technology Department of PhysicsDalian Deutsches Elektronen-synchrotron DEsY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential super Proton Proton Collider(sPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(sR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the sR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Homer家族在注意缺陷多动障碍大鼠海马组织中的表达

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实用儿科临床杂志 2009年第18期24卷 1434-1436页

作者：洪琴池霞郭锡熔童梅玲张敏陈荣华费莉郭梅潘晓勤南京医科大学附属南京市妇幼保健院儿保科南京210004 南京医科大学儿科医学研究所南京210029

目的评价Homer家族在注意缺陷多动障碍(ADHD)动物模型幼年自发性高血压大鼠(sHR)及其对照Wistar京都大鼠(WKY)海马中的表达差异,分析其与ADHD患儿学习记忆功能障碍的关系。方法sHR大鼠12只、WKY大鼠11只,平衡数天,断头处死,取其海马组... 详细信息

目的评价Homer家族在注意缺陷多动障碍(ADHD)动物模型幼年自发性高血压大鼠(sHR)及其对照Wistar京都大鼠(WKY)海马中的表达差异,分析其与ADHD患儿学习记忆功能障碍的关系。方法sHR大鼠12只、WKY大鼠11只,平衡数天,断头处死,取其海马组织。取8只sHR大鼠及7只WKY大鼠海马组织,利用反转录聚合酶链反应(RT-PCR)技术检测sHR/WKY大鼠海马组织中Homer1a、Homer1b/c、Homer2a/b mRNA的表达。取其余4只sHR和4只WKY大鼠海马组织,利用Western blot技术检测在2组大鼠海马组织中存在差异表达的上述基因蛋白在sHR/WKY大鼠海马中的表达。结果***大鼠Homer 1a、Ho-mer2a/b mRNA表达量均较WKY大鼠显著降低(t=2.95 P0.05)。***大鼠海马组织中Homer1a、Homer2a/b蛋白表达量均较WKY大鼠显著降低(t=4.31,3.27Pa<0.01)。结论Homer1a、Homer2a/b可能在ADHD发病机制中发挥重要作用。

关键词：注意缺陷多动障碍 Homer 海马

盐酸哌甲酯对自发性高血压大鼠行为及前额叶突触超微结构的影响

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实用儿科临床杂志 2010年第24期25卷 1856-1858页

作者：池霞洪琴郭锡熔童梅玲张敏陈荣华费莉郭梅潘晓勤南京医科大学附属南京市妇幼保健院儿保科南京210004 南京医科大学儿科医学研究所南京210029

目的观察盐酸哌甲酯(MPH)对自发性高血压大鼠(sHR)行为及前额叶突触超微结构的影响,探讨注意缺陷多动障碍(ADHD)可能存在的发病机制。方法将22只ADHD动物模型sHR随机分为2组:MPH给药组(MPH组,n=11)和9g.L-1盐水对照组(sAL组,n=11),分别... 详细信息

目的观察盐酸哌甲酯(MPH)对自发性高血压大鼠(sHR)行为及前额叶突触超微结构的影响,探讨注意缺陷多动障碍(ADHD)可能存在的发病机制。方法将22只ADHD动物模型sHR随机分为2组:MPH给药组(MPH组,n=11)和9g.L-1盐水对照组(sAL组,n=11),分别予MPH(***-1)、9g.L-1盐水各1mL,2次.d-1,共14d。分别利用Làt迷宫、Morris水迷宫观察2组大鼠自发活动、非选择性注意力和学习记忆能力;完成行为学实验后,每组各随机抽取3只,利用电镜技术观察2组大鼠前额叶皮质突触超微结构。结果 1.Làt迷宫中,给药前MPH组水平活动、直立次数和斜搭次数与sAL组比较差异无统计学意义;给药14d后,MPH组水平活动、直立次数和斜搭次数较sAL组显著降低(Pa=0.00)。Morris水迷宫实验第1天,MPH组潜伏期和总路程与sAL组比较差异无统计学意义;第2天、第3天,MPH组潜伏期和总路程较sAL组显著降低(Pa=0.01,0.02)。2.电镜结果显示MPH组较sAL组突触数目增加,突触间隙增宽,突触后致密物厚度增加,差异有统计学意义(Pa=0.01,0.02,0.01);2组突触活性区长度比较差异无统计学意义。结论 MPH长期用药在改善sHR行为的同时可引起sHR前额叶突触超微结构的变化,提示突触超微结构的异常可能参与ADHD的发病。

关键词：自发性高血压盐酸哌甲酯突触超微结构行为大鼠

Mortality and Morbidity of Extremely Low Birth Weight Infants in the Mainland of china： A Multi-center study

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chinese medical Journal 2015年第20期128卷 2743-2750页

作者： Hui-Jia lin li-Zhong Du xiao-Lu Ma li-Ping shi Jia-hua pan xiao-mei tong Qiu-Ping li Jian-guo Zhou Bing Yi ling liu Yun-Bing chen Qiu-Fen Wei Hui-qing Wu mei li Cui-qing li xi-rong Gao shi-Wen xia Wen-Bin li Chao-Ying Ya ling He Kun liang xiao-Yu Zhou shu-Ping Han qin Lyu Yin-Ping Qiu Wen li Dong-mei chen hong-Ru Lu xiao-hong liu hong liu Zhen-Lang lin li liu Jia-Jun Zhu hong xiong shao-Jie Yue si-Qi Zhuang department of Neonatal Intensive Care Unit Children's Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang 310053 China department of Neonatology Anhui Provincial Hospital Hefei Anhui 230001 China department of pediatrics Peking University Third Hospital Beijing 100191 China department of Neonatology BaYi Children's Hospital of the General Military Hospital of Beijing People's Liberation Army Beijing 100000 China department of Neonatology Children's Hospital of Fudan University Shanghai 200032 China department of Neonatology Gansu Provincial Maternity and Children-care Hospital Lanzhou Gansu 730050 China department of Neonatotogy Guiyang Maternal and Child Health Care Hospital Guiyang Guizhou 550003 China department of Neonatology Women and Children Hospital of Guangdong Province Guangzhou Guangdong 510010 China department of Neonatology Guangxi Maternal and Child Health Hospital Nanning Guangxi 530003 China department of Neonatology The Third Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong 510150 China department of Neonatology Harbin Children's Hospital Harbin Heilongjiang 150010 China department of Neonatology Children's Hospital of Hebei Province Shijiazhuang Hebei 050031 China department of Neonatology Hunan Children's Hospital Changsha Hunan 410007 China department of Neonatology Hubei Maternity and Child Heath Hospital Wuhan Hubei 430070 China department of pediatrics Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China department of Neonatology The First Hospital of Jilin University Changchun Jilin 130021 China department of Neonatology Jiangxi Provincial Children's Hospital Nanchang Jiangxi 330006 China department of Pediatric First Affiliated Hospital of Kunming Medical University Kunming Yunnan 650032 China department of Neonatotogy Nanjing Children's Hospital of Nanjing Medical University Nanjing Jiangsu 320100 China De

Background： With the progress ofperinatal medicine and neonatal technology, more and more extremely low birth weight （ELBW） survived all over the world. This study was designed to investigate the short-term ontcomes of ELBW infants during their Neonatal Intensive Care Unit （NICU） stay in the mainland of china. Methods： All infants admitted to 26 NICUs with a birth weight （BW）〈1000 g were included between January 1,2011 and December 31,2011. All the data were collected retrospectively from clinical records by a prospectively designed questionnaire. The data collected from each NICU transmitted to the main institution where the results were aggregated and analyzed. Categorical variables were performed with Pearson chi-square test. Binary Logistic regression analysis was used to detect risk factors. Results： A total of 258 ELBW infants were admitted to 26 NICUs, of whom the mean gestational age （GA） was 28.1 ± 2.2 weeks, and the mean BW was 868 ± 97 g. The overall survival rate at discharge was 50.0%. Despite aggressive treatment 60 infants （23.3%） died and another 69 infants （26.7%） died after medical care withdrawal. Furthermore, the survival rate was significantly higher in coastal areas than inland areas （53.6% vs. 35.3%, P = 0.019）. BW 〈750 g and GA 〈28 weeks were the largest risk factors, and being small for gestational age was a protective factor related to mortality. Respiratory distress syndrome was the most common complication. The incidence of patent ductus arteriosus, intraventricular hemorrhage, periventricular leukomalacia, bronchopulmonary dysplasia, retinopathy of prematurity was 26.2%, 33.7%, 6.7%, 48.1%, and 41.4%, respectively. Ventilator associated pneumonia was the most common hospital acquired infection during hospitalization. Conclusions： Our study was the first survey that revealed the present status of ELBW infants in the mainland of china. The mortality and morbidity of ELBW infants remained high as compared to other developed countries.

关键词： Extremely Low Birth Weight Infant Mortality National survey

Lung-protective Ventilation in Patients with Brain Injury： A Multicenter Cross-sectional study and Questionnaire survey in china

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chinese medical Journal 2016年第14期129卷 1643-1651页

作者： Xu-Ying Luo Ying-hong Hu xiang-Yuan Cao Yan Kang li-Ping liu shou-hong Wang rong-guo Yu xiang-You Yu xia zhang Bao-shan li Zeng-xiang Ma Yi-Bing Weng Heng zhang De-Chang chen Wei chen Wen-Jin chen xiu-mei chen Bin Du mei-li Duan Jin Hu Yun-Feng Hoang Gui-Jun Jia li-hong li Yu-min liang Bing-Yu qin xian-Dong Wang Jian xiong li-mei Yan Zheng-Ping Yang chen-ming Dong Dong-xin Wang qing-Yuan Zhan shuang-lin FU lin Zhao Qi-Bing huang Ying-Guang xie xiao-Bo huang guo-Bin zhang Wang-Bin Xu Yuan Xu Yaling liu He-ling Zhao rong-qing sun ming sun qing-hong cheng xin Qu xiao-Feng Yang ming Xu Zhong-hua shi Han chen Xuan He Yan-lin Yang Guang-Qiang chen xiu-mei sun Jian-xin Zhou department of Critical Care Medicine Beijing Tiantan Hospital Capital Medical University Beijing 100050 China department of Critical Care Medicine Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang 310009 China department of Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan Ningxia 750004 China department of Critical Care Medicine West China Hospital Sichuan University Chengdu Sichuan 610041 China Neurological Intensive Care Unit Beijing Tiantan Hospital Capital Medical University Beijing 100050 China department of Critical Care Medicine Guangdong General Hospital Guangzhou Guangdong 510000 China surgical Intensive Care Unit Fujian Province Hospital Fuzhou Fujian 350000 China department of Critical Care Medicine First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China department of Critical Care Medicine Bethune International Peace Hospital Shijiazhuang Hebei 050000 China department of Critical Care Medicine Yuncheng Central Hospital Yuncheng Shanxi 044000 China department of Emergency and Critical Care Medicine Cangzhou People's Hospital Cangzhou Hebei 061000 China department of Critical Care Medicine Beijing Luhe Hospital Capital Medical University Beijing 101100 China department of Critical Care Medicine First Hospital of China Medical University Shenyang Liaoning 110000 China department of Critical Care Medicine Shanghai Changzheng Hospital Shanghai 200000 China department of Critical Care Medicine Beijing Shijitan Hospital Capital Medical University Beijing 100038 China department of Critical Care Medicine Xuanwu Hospital Capital Medical University Beijing 100053 China department of Critical Care Medicine Miyun County Hospital Beijing 100038 China medical Intensive Care Unit Peking Union Medical College Hospital Beijing 101500 China department of Critical Care Medicine Beijing Friendship Hospital Capital Medical University Beijing 100050 Chin

Background： Over the years, the mechanical ventilation （MV） strategy has changed worldwide. The aim of the present study was to describe the ventilation practices, particularly lung-protective ventilation （LPV）, among brain-injured patients in china. Methods： This study was a multicenter, 1-day, cross-sectional study in 47 Intensive Care Units （ICUs） across china. Mechanically ventilated patients （18 years and older） with brain injury in a participating ICU during the time of the study, including traumatic brain injury, stroke, postoperation with intracranial tumor, hypoxic-ischemic encephalopathy, intracranial infection, and idiopathic epilepsy, were enrolled. Demographic data, primary diagnoses, indications for MV, MV modes and settings, and prognoses on the 60th day were collected. Multivariable logistic analysis was used to assess factors that might affect the use of LPV. Results： A total of 104 patients were enrolled in the present study, 87 （83.7%） of whom were identified with severe brain injury based on a Glasgow Coma scale 〈8 points. synchronized intermittent mandatory ventilation （sIMV） was the most frequent ventilator mode, accounting for 46.2% of the entire cohort. The median tidal volume was set to 8.0 ml/kg （interquartile range [IQR], 7.0-8.9 ml/kg） of the predicted body weight; 50 （48.1%） patients received LPV. The median positive end-expiratory pressure （PEEP） was set to 5 cmH20 （IQR, 5-5 cmH20）. No PEEP values were higher than 10 cmH20. Compared with partially mandatory ventilation, supportive and spontaneous ventilation practices were associated with LPV. There were no significant differences in mortality and MV duration between patients subjected to LPV and those were not. Conclusions： Among brain-injured patients in china, sIMV was the most frequent ventilation mode. Nearly one-half of the brain-injured patients received LPV. Patients under supportive and spontaneous ventilation were more likely to receive LPV.

关键词： Brain Injury Epidemiology Lung-protective Ventilation Mechanical Ventilation

The first data release(DR1) of the LAMOsT regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-li Luo Yong-Heng Zhao Gang Zhao li-Cai Deng xiao-Wei liu Yi-Peng Jing Gang Wang Hao-tong zhang Jian-rong shi xiang-Qun Cui Yao-Quan Chu guo-Ping li Zhong-Rui Bai Yue Wu Yan Cai shu-Yun Cao Zi-huang Cao Jeffrey L.Carlin Hai-Yuan chen Jian-Jun chen Kun-xin chen li chen Xue-Lei chen xiao-Yan chen Ying chen Norbert Christlieb Jia-Ru Chu chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning Fu Peng Gao Xue-fei Gong Bo-Zhong Gu Yan-xin guo Zhan-Wen Han Bo-liang He Jin-liang Hou Yong-Hui Hou Wen Hou hong-Zhuan Hu Ning-sheng Hu Zhong-Wen Hu Zhi-Ying Huo Lei Jia Fang-hua Jiang xiang Jiang Zhi-Bo Jiang Ge Jin xiao Kong Xu Kong Ya-Juan Lei Ai-hua li Chang-hua li Guang-Wei li Hai-Ning li Jian li Qi li shuang li sha-sha li xin-Nan li Yan li Yin-Bi li Ye-Ping li Yuan liang chien-cheng lin Chao liu Gen-rong liu Guan-Qun liu Zhi-Gang liu Wen-Zhi Lu Yu Luo Yin-Dun Mao Heidi Newberg Ji-Jun Ni Zhao-xiang Qi Yong-Jun Qi shi-Yin shen Huo-ming shi Jing song Yi-Han song Ding-Qiang su hong-Jun su Zheng-hong Tang qing-sheng Tao Yuan Tian Dan Wang Da-Qi Wang Feng-fei Wang guo-min Wang Hai Wang hong-chi Wang Jian Wang Jia-Ning Wang Jian-ling Wang Jian-Ping Wang Jun-xian Wang Lei Wang Meng-xin Wang shou-Guan Wang shu-qing Wang xia Wang Ya-Nan Wang You Wang Yue-fei Wang You-Fen Wang Peng Wei ming-Zhi Wei hong Wu Ke-fei Wu Xue-Bing Wu Yu-Zhong Wu xiao-Zheng xing ling-Zhe Xu xin-Qi Xu Yan Xu Tai-sheng Yan De-hua Yang Hai-Feng Yang Hui-qin Yang ming Yang Zheng-Qiu Yao Yong Yu Hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-min Yuan Chao Zhai En-Peng zhang hua-Wei zhang Jian-Nan zhang li-Pin zhang Wei zhang Yong zhang Yan-xia zhang Zheng-Chao zhang ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu si-cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences department of Astronomy Peking University shanghai Astronomical Observatory Chinese Academy of Sciences nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences university of science and Technology of china department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber spectroscopic Telescope（LAMOsT） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QsOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOsT DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOsT Pilot Data Release in August 2012. The regular survey started in september 2012, and completed its first year of operation in June 2013. The LAMOsT DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（sNR） ≥ 10. All data with sNR ≥ 2 are formally released as LAMOsT DR1 under the LAMOsT data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITs structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients

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chinese medical Journal 2013年第12期126卷 2276-2280页

作者： ZHENG Ying CAI Guang-yan chen xiang-mei FU Ping chen Jiang-hua DING xiao-qiang YU Xue-qing liN hong-li liU Jian xiE Ru-juan WANG li-ning NI Zhao-hui liU Fu-you YIN Ai-ping xiNG Chang-ying WANG li sHI Wei liU Jian-she HE Ya-ni DING guo-hua li Wen-ge WU Guang-li MIAO li-ning chen Nan sU Zhen mei Chang-lin ZHAO Jiu-yang GU Yong BAI Yun-kai LUO Hui-min liN shan chen Meng-hua GONG li YANG Yi-bin YANG xiao-ping li Ying WAN Jian-xin WANG Nian-song li Hai-ying xi Chun-sheng HAO li XU Yan FANG Jing-ai liU Bi-cheng li rong-shan WANG rong zhang Jing-hong WANG Jian-qin LOU Tan-qi sHAO Feng-min mei Feng liU Zhi-hong YUAN Wei-jie sUN shi-ren zhang ling ZHOU Chun-hua chen qin-kai JIA shun-lian GONG Zhi-feng GUAN Guang-ju xia Tian Zhong liang-bao department of Nephrology State key Laboratory of Kidney Disease Chinese PLA General Hospital Beijing 100853 China Nephrology Institute of the chinese People's liberation Army Chinese People's Liberation Army Key Laboratory of Nephrology Beijing 100853 China department of Nephrology West China Hospital of Sichuan University Chengdu Sichuan 610041 China department of Nephrology First Affiliated Hospital School of Medicine Zhejiang University Hangzhou Zhejiang 310003 China department of Nephrology Zhongshan Hospital Fudan University Shanghai 200032 China department of Nephrology First Affiiated Hospital of Sun Yat-sen University Guangzhou Guangdong 510080 China department of Nephrology First Affiliated Hospital of Dalian Medical University Dalian Liaoning 116011 China department of Nephrology First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China department of Nephrology First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China department of Nephrology First Afftiated Hospital of China Medical University Shenyang Liaoning 110001 China department of Nephrology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200025 China department of Nephrology Second Xiangya Hospital Central South University Changsha Hunan 410000 China department of Nephrology First Affiliated Hospital of Medical College Xi'an Jiaotong University Xi'an Shaanxi 710061 China department of Nephrology First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital) Nanjing Jiangsu 210029 China department of Nephrology Sichuan Provincial People's Hospital Chengdu Sichuan 610072 China department of Nephrology Guangdong Provincial People's Hospital Guangzhou Guangdong 510030 China department of Nephrology Affliated Xiehe Hospital Tongji Medical College Huazhong Science and Technology University Wuhan Hubei 430022 China department of Nephrology Daping Hospital Third Military Medi

Background Data on the epidemiology of hypertension in chinese non-dialysis chronic kidney disease （CKD） patients are *** aim of the present study was to investigate the prevalence,awareness,treatment,and control of hypertension in the non-dialysis CKD patients through a nationwide,multicenter study in *** The survey was performed in 61 tertiary hospitals in 31 provinces,municipalities,and autonomous regions in china （except hong Kong,Macao,and Taiwan）.Trained physicians collected demographic and clinical data and measured blood pressure （BP） using a standardized *** was defned as systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg,and/or use of antihypertensive *** 〈140/90 mmHg and 〈130/80 mmHg were used as the 2 thresholds of hypertension *** multivariate logistic regression with adjustment for sex and age,we analyzed the association between CKD stages and uncontrolled hypertension in non-dialysis CKD *** The analysis included 8927 non-dialysis CKD *** prevalence,awareness,and treatment of hypertension in non-dialysis CKD patients were 67.3%,85.8%,and 81.0%,*** hypertensive CKD patients,33.1% and 14.1% had controlled BP to 〈140/90 mmHg and 〈130/80 mmHg,*** successive CKD stages,the prevalence of hypertension in non-dialysis CKD patients increased,but the control of hypertension decreased （P〈0.001）.When the threshold of BP 〈130/80 mmHg was considered,the risk of uncontrolled hypertension in CKD 2,3a,3b,4,and 5 stages increased 1.3,1.4,1.4,2.5,and 4.0 times compared with CKD 1 stage,respectively （P〈0.05）.Using the threshold of 〈140/90 mmHg,the risk of uncontrolled hypertension increased in advanced stages （P〈0.05）.Conclusions The prevalence of hypertension chinese non-dialysis CKD patients was high,and the hypertension control was *** successive CKD stages,the risk of uncontrolled hypertension increased.

关键词： non-dialysis chronic kidney disease chronic kidney disease stages hypertension epidemiology

南京市322例2岁幼儿贝利发育量表调查分析

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实用儿科临床杂志 2010年第11期25卷 832-834页

作者：池霞洪琴姚天红徐亚琴戴家振张敏陈宁川郭锡熔童梅玲柯晓燕邓慧华陆祖宏南京医科大学附属南京市妇幼保健院儿保科南京210004 南京医科大学附属脑科医院儿童心理卫生研究中心南京210029 东南大学儿童发展与学习科学教育部重点实验室南京210096

目的通过分析南京322例2岁幼儿智能发育状况及特征,为合理指导婴幼儿早期综合发展提供科学依据。方法采用贝利婴幼儿发育量表对随访的322名2岁南京城区幼儿进行智能发育评估,并对其结果进行研究分析。结果 1.幼儿322例中智力发展指数(M... 详细信息

目的通过分析南京322例2岁幼儿智能发育状况及特征,为合理指导婴幼儿早期综合发展提供科学依据。方法采用贝利婴幼儿发育量表对随访的322名2岁南京城区幼儿进行智能发育评估,并对其结果进行研究分析。结果 1.幼儿322例中智力发展指数(MDI)≤69占3.1%,精神运动发展指数(PDI)≤69占5.6%;***均值为114.34±19.65,显著高于PDI均值(101.73±21.53)(t=9.71,P0.05)。结论本研究人群智能发育迟滞发生率与WHO报道的精神发育迟滞发病率基本一致;幼儿智能发育存在运动发展和智力发展的差异及性别差别。因此,在儿童保健工作中应切实落实儿童早期智能筛查,指导家长进行智力与运动发育并重的科学养育方法 ,促进儿童的早期全面发展。

关键词：贝利婴幼儿发育量表智能发育早期干预儿童

新思路·新技术——中药复方新药研发相关重大科学和技术问题

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中国药理学与毒理学杂志 2020年第4期34卷 241-260页

作者：蒋宁杜保民杜冠华段大跃方坚松高兴华高秀梅顾金辉郭彦飞侯悦黄晏李琦林志彬刘建勋陆茵吕圭源聂红庞晓斌齐晓甜秦雪梅任巧任远任周新茹祥斌申竹芳石京山孙建宁孙蓉孙晓波王陈王梅王同兴吴春福谢宗杰徐惠波薛云丽杨宝学杨奎余林中张丹参张兰张林张永鹤张永祥赵勤实周玉枝朱焰周文霞军事科学院军事医学研究院毒物药物研究所北京100850 北京北大维信生物科技有限公司北京100094 中国医学科学院北京协和医学院药物研究所北京100050 西南医科大学附属中医医院中医药表型组学中心四川泸州646000 广州中医药大学科技创新中心广东广州510006 中国药科大学江苏南京210009 天津中医药大学天津301617 国家卫生健康委员会科技教育司重大专项处北京100044 东北大学辽宁沈阳110819 中国中医科学院中药研究所北京100700 北京大学基础医学院北京100191 中国中医科学院西苑医院北京100091 南京中医药大学药学院江苏南京210023 浙江中医药大学现代中药与健康产品研究所浙江杭州310053 广东省药效物质基础和创新药物研究重点实验室广东广州510632 河南大学药学院河南开封475004 山东大学高等医学研究院山东济南250012 山西大学中医药现代研究中心山西太原030006 甘肃中医药大学甘肃兰州730000 河南中医药大学河南郑州450046 遵义医科大学贵州遵义563003 北京中医药大学北京100029 中国医学科学院药用植物研究所北京100193 莱顿大学-欧洲中医药和天然化合物中心荷兰莱顿天士力国际基因网络药物创新中心有限公司天津300410 沈阳药科大学辽宁沈阳110016 吉林省中医药科学院吉林长春130012 山东绿叶制药有限公司山东烟台264003 成都中医药大学四川成都611137 南方医科大学广东广州510515 河北科技大学河北石家庄050018 首都医科大学宣武医院北京100053 中国科学院昆明植物研究所云南昆明650201 复旦大学上海200433

"第十二届全国中药与天然药物药理学术会议"于2019年10月11-13日在天津市社会山国际会议中心酒店举行。会议期间,中国药理学会中药与天然药物药理专业委员会召开了"中药复方新药研发相关重大科学和技术问题"专题研讨会。研讨会分为主题... 详细信息

"第十二届全国中药与天然药物药理学术会议"于2019年10月11-13日在天津市社会山国际会议中心酒店举行。会议期间,中国药理学会中药与天然药物药理专业委员会召开了"中药复方新药研发相关重大科学和技术问题"专题研讨会。研讨会分为主题报告和综合讨论2部分。主题报告由中国药理学会中药与天然药物药理专业委员会副主任委员吴春福教授主持,刘建勋、孙晓波、段大跃和吕圭源教授作主题报告。中国药理学会理事长兼中药与天然药物药理专业委员会主任委员张永祥研究员主持综合讨论,国家卫生健康委员会科技教育司重大专项处顾金辉处长全程参加。与会专家围绕中药复方新药研发相关重大科学和技术问题进行了广泛、深入的讨论。本文整理了专家们的主要观点和建议,希望能为中药复方新药研发提供新思路和新技术,为提高我国中药复方新药的研发水平发挥积极的推动作用。

关键词：中药复方新药研发新思路新技术