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A Characterization of the Smallest Suzuki 2-Group

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Acta Mathematica Sinica,English Series 2008年第12期24卷 2011-2014页

作者： qin hai zhang Department of Mathematics Shanxi Normal University Linfen 041004 P. R. China

Let G be a finite nonabelian group which has no abelian maximal subgroups and satisfies that any two non-commutative elements generate a maximal subgroup. Then G is isomorphic to the smallest Suzuki 2-group of order 64.

关键词： metacyclic groups minimal nonabelian groups Suzuki 2-groups

Finite p-Groups with a Class of Complemented Normal Subgroups

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Acta Mathematica Sinica,English Series 2017年第2期33卷 278-286页

作者： Li Fang WANG qin hai zhang Mathematics Department Shanxi Normal University Linfen 041004 P. R. China

Assume G is a finite group and H a subgroup of G. If there exists a subgroup K of G such that G = HK and H ∩ K = 1, then K is said to be a complement to H in G. A finite p-group G is called an NC-group if all its proper normal subgroups not contained in de（G） have complements. In this paper, some properties of NC-groups are investigated and some classes of NC-groups are classified. Keywords Finite p-groups, normal subgroups, subgroup complement

关键词： Finite p-groups normal subgroups subgroup complement

Finite 2-generator equilibrated p-groups

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Science China Mathematics 2007年第6期50卷 814-820页

作者： qin-hai zhang Cui-juan SUN hai-peng QU Ming-yao XU School of Mathematics and Computer Sciences Shanxi Normal UniversityLinfen 041004China

Following Blackburn, Deaconescu and Mann, a group G is called an equilibrated group if for any subgroups H,K of G with HK = KH, either H≤NG(K) or K≤NG(H). Continuing their work and based on the classification of metacyclic p-groups given by Newman and Xu, we give a complete classification of 2-generator equilibrated p-groups in this note.

关键词： equilibrated group metacyclic group finite p-group minimal non-abelian group 20D15

Changes of serum alpha-fetoprotein and alpha-fetoprotein-L3 after hepatectomy for hepatocellular carcinoma: prognostic significance

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Hepatobiliary & Pancreatic Diseases International 2012年第6期11卷 618-623页

作者： Xiao-Feng zhang, Zheng-Feng Yin, Kui Wang, Zong-qin zhang, hai-Hua Qian,Le-Hua ShiAuthor Affiliations: The 4th Department of Hepatic Surgery ,Molecular Oncology Laboratory , Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China [a] The 4th Department of Hepatic Surgery Eastern Hepatobiliary Surgery Hospital Second Military Medical University Shanghai 200438 China [b] Molecular Oncology Laboratory Eastern Hepatobiliary Surgery Hospital Second Military Medical University Shanghai 200438 China

BACKGROUND: Alpha-fetoprotein (AFP) is the most established tumor marker of hepatocellular carcinoma (HCC), but one of its limitations is non-specificity. Many studies have demonstrated that alpha-fetoprotein-L3 (AFP-L3) is more specific than AFP in the early diagnosis and prognosis of HCC. However, there is a lack of knowledge about the post-hepatectomy profiles of serum AFP and AFP-L3 values in HCC patients. To identify the profiles after surgical resection of HCC, we analyzed the correlation between the profiles and postoperative HCC recurrence or survival, and evaluated their utility in predicting postoperative therapeutic efficacy and prognosis. METHODS: From August 2003 to December 2004, 318 patients with positive serum AFP who had received surgical resections were enrolled in this study. Preoperative and postoperative serum AFP and AFP-L3 levels were measured simultaneously and regularly, and their postoperative profiles during a long term follow-up were recorded and summarized. RESULTS: A high ratio of AFP-L3 to total AFP was shown to correlate with pathologic features of aggressiveness. The overall 1-, 3-, and 5-year recurrence rates of the whole series were 28% 57%, and 84%, and the overall survival rates were 86%, 61% and 33%, respectively. The changes of serum AFP and AFP-L3 after hepatectomy for HCC were classified into 3 groups (group A: AFP-L3 undetectable; group B: AFP-L3 10%). Patients with positive postoperative AFP-L3had significantly earlier recurrence than those with negative results. The overall survival was significantly shorter in the positive groups than in the groups negative for postoperative ***: Post-hepatectomy changes in serum AFP and AFP-L3 levels occurred in three distinct patterns, which were closely correlated with HCC recurrence and patient survival with different prognostic values.

关键词： hepatocellular carcinoma hepatectomy alpha-fetoprotein alpha-fetoprotein-L3

基于改进干扰观测器的虚拟轴机床滑模控制研究

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工程设计学报 2016年第5期23卷 501-505页

作者：李琴刘海东张祺攀枝花学院机械工程学院四川攀枝花617000 四川大学制造科学与工程学院四川成都610065

圆弧齿轮加工用虚拟轴机床伺服系统存在的不确定性会影响系统的性能,从而降低圆弧齿轮的加工精度;同时,滑模控制中抖动现象会影响控制的精度和稳定性.为提高虚拟轴机床的加工精度和抑制滑模控制中的抖动现象,提出了基于改进观测器的滑... 详细信息

圆弧齿轮加工用虚拟轴机床伺服系统存在的不确定性会影响系统的性能,从而降低圆弧齿轮的加工精度;同时,滑模控制中抖动现象会影响控制的精度和稳定性.为提高虚拟轴机床的加工精度和抑制滑模控制中的抖动现象,提出了基于改进观测器的滑模变结构控制算法来控制虚拟轴机床的伺服电机,算法中采用该干扰观测器对系统中的不确定性进行观测,利用饱和函数代替符号函数来抑制滑模控制中的抖动现象.推导了基于改进观测器的滑模变结构控制律,并证明了所设计控制器的稳定性;为验证算法的有效性,在MATLAB中进行了仿真,仿真结果表明:所提出的算法能够有效地观测系统中存在的不确定性因素,并抑制滑模控制中的抖动现象,系统具有较强的位置跟踪性能和抗干扰能力.

关键词：虚拟轴机床不确定性观测器抖动仿真

The emerging role of nitric oxide in the synaptic dysfunction of vascular dementia

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Neural Regeneration Research 2025年第2期20卷 402-415页

作者： Xiaorong zhang Zhiying Chen Yinyi Xiong qin Zhou Ling-Qiang Zhu Dan Liu Department of Pathology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Jiujiang Clinical Precision Medicine Research Center JiujiangJiangxi ProvinceChina Center for Cognitive Science and Transdisciplinary Studies Jiujiang UniversityJiangxi ProvinceChina Department of Neurology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Rehabilitation Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Pathophysiology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

With an increase in global aging,the number of people affected by cerebrovascular diseases is also increasing,and the incidence of vascular dementia-closely related to cerebrovascular risk-is increasing at an epidemic ***,few therapeutic options exist that can markedly improve the cognitive impairment and prognosis of vascular dementia *** in Alzheimer’s disease and other neurological disorders,synaptic dysfunction is recognized as the main reason for cognitive *** oxide is one of the ubiquitous gaseous cellular messengers involved in multiple physiological and pathological processes of the central nervous ***,nitric oxide has been implicated in regulating synaptic plasticity and plays an important role in the pathogenesis of vascular *** review introduces in detail the emerging role of nitric oxide in physiological and pathological states of vascular dementia and summarizes the diverse effects of nitric oxide on different aspects of synaptic dysfunction,neuroinflammation,oxidative stress,and blood-brain barrier dysfunction that underlie the progress of vascular ***,we propose that targeting the nitric oxide-sGC-cGMP pathway using certain specific approaches may provide a novel therapeutic strategy for vascular dementia.

关键词： endoplasmic reticulum stress endothelial nitric oxide synthase gene therapy nitric oxide NO-sGC-cGMP pathway synaptic dysfunction vascular dementia

Phylogenetic analysis of the species with awnless lemmas in Roegneria(Poaceae,Triticeae) based on single copy of nuclear gene DMC1

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Phylogenetic analysis of the species with awnless lemmas in ...

尾叶桉COMT和CCoAOMT基因定向调控木质素单体合成的烟草转化研究

第六届全国小麦基因组学及分子育种大会

作者： Ying-Xia Lei Xing Fan Yi Wang Li-Na Sha Hou-Yang Kang Yong-Hong Zhou hai-qin zhang Triticeae Research Institute Sichuan Agricultural University Key Laboratory of Crop Genetic Resources and Improvement Ministry of EducationSichuan Agricultural University

To investigate the phylogenetic relationships among species with awnless lemmas in Roegneria and related diploid genera,the possible genomic constitution and genome donor of species with awnless lemmas in *** analyses of cDNA1(DMC1) sequences,our results showed that:(1) Roegneria grandis has StStYY,However the St genome from *** is different from St genome and is homologous with Y genome.(2) Roegneria alashanica has StStYY.(3) Roegneria elytrigioides has StStStSt genomes and should therefore be classified as Pseudoroegneria elytrigioides.(4)The species with awnless lemmas in Roegneria have different St genome donor from species of Pseudoroegneria.(5)We prefer the suggestion that the Y genome is closely related to the St genome,however,the data do not certify that the St and Y genomes have the same origin.

关键词： awnless lemmas Roegneria DMC1 Phylogeny Polyploid

来源： cnki会议评论

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中国生物工程杂志 2018年第3期38卷 24-32页

作者：陈博雯刘海龙肖玉菲覃子海张烨张晓宁广西壮族自治区林业科学研究院国家林业局中南速生材繁育实验室广西优良用材林资源培育重点实验室

目的：利用烟草遗传转化体系,研究尾叶桉（Eucalyptus urophylla）咖啡酸氧甲基转移酶基因（Eu COMT）和咖啡酰Co A氧甲基转移酶基因（Eu CCo AOMT）对木质素单体合成的定向调控效果。方法：分别利用Eu COMT的正义片段、Eu CCo AOMT的全... 详细信息

目的：利用烟草遗传转化体系,研究尾叶桉（Eucalyptus urophylla）咖啡酸氧甲基转移酶基因（Eu COMT）和咖啡酰Co A氧甲基转移酶基因（Eu CCo AOMT）对木质素单体合成的定向调控效果。方法：分别利用Eu COMT的正义片段、Eu CCo AOMT的全长RNAi片段进行单基因和二价基因的烟草转化研究,并对转基因烟草植株中目标基因表达水平、木质素和纤维素的含量、茎部解剖结构及木质素单体含量进行检测。结果：分别获得了转基因植株C-S（转Eu COMT正义片段）、CR（转Eu CCo AOMT全长RNAi片段）、C-CR（Eu COM和Eu CCo AOMT二价基因转化）。烟草中转入的正义Eu COMT的片段能够正常表达,而Eu CCo AOMT的全长RNAi片段对烟草CCo AOMT基因引发了强烈的抑制。转基因烟草的生长形态、木质素、纤维含量及解剖结构与野生型无显著差异。转基因植株C-S中G木质素含量升高17.72%,S/G值降低17.99%;CR中S/G值升高61.62%,CCR中G木质素降幅达到57.38%,S/G比值升幅达到114.94%。结论：抑制CCo AOMT对G木质素合成具有显著的抑制效果,Eu COMT和Eu CCo AOMT二价基因转化对S/G比值的定向调控效果最为理想。

关键词：二价基因转化木质素单体合成定向调控烟草转化

Non-coding RNAs in acute ischemic stroke:from brain to periphery

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Neural Regeneration Research 2025年第1期20卷 116-129页

作者： Shuo Li Zhaohan Xu Shiyao zhang Huiling Sun Xiaodan qin Lin Zhu Teng Jiang Junshan Zhou Fuling Yan Qiwen Deng Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Zhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsu ProvinceChina General Clinical Research Center Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina

Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and *** predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain *** innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental *** expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic ***,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and *** particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic *** this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and *** from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.

关键词： acute ischemic stroke apoptosis blood–brain barrier damage circular RNAs excitatory toxicity long non-coding RNAs microRNAs neuroinflammation non-coding RNAs oxidative stress