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Carcinoma of the gastroesophageal junction in Chinese patients

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World Journal of Gastroenterology 2012年第48期18卷 7134-7140页

作者： qin Huang Department of Pathology Nanjing Drum Tower Hospital Department of Pathology and Laboratory Medicine Veterans Affairs Boston Healthcare System and Harvard Medical School

Carcinoma of the gastroesophageal junction(GEJ) is defined as carcinoma that crosses the GEJ line,irrespective of where the tumor epicenter is *** group of cancer is rare but *** on study results from the majority of epidemiologic and clinicopathologic investigations carried out in Western countries,this cancer is believed to arise from Barrett's esophagus(BE) and includes both distal esophageal and proximal gastric carcinomas because of similar characteristics in epidemiology,clinicopathology,and molecular pathobiology in relation to *** such,the most recent American Joint Committee on Cancer staging manual requires staging all GEJ carcinomas with the rule for esophageal adenocarcinoma(EA).This mandate has been challenged recently by the data from several studies carried out mainly in Chinese *** emerging evidence derivedfrom those studies suggests:(1) both BE and EA are uncommon in the Chinese population;(2) almost all GEJ cancers in Chinese arise in the proximal stomach and show the features of proximal gastric cancer,not those of EA;(3) application of the new cancer staging rule to GEJ cancer of Chinese patients cannot stratify patients' prognosis effectively;and(4) prognostic factors of GEJ cancer in Chinese are similar,but not identical,to those of *** conclusion,the recent evidence suggests that GEJ cancer in Chinese shows distinct clinicopathologic characteristics that are different from *** investigations in molecular pathology may help illustrate the underlying pathogenesis mechanisms of this cancer in Chinese patients and better manage patients with this fatal disease.

关键词： Esophagus Stomach Cancer Gastroesophageal junction Staging Barrett's esophagus

Revised Iterative Solution for Groundstate of Schro^edinger Equation

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Communications in Theoretical Physics 2004年第1X期42卷 37-42页

作者： ZHAOWei-qin ChinaCenterofAdvancedScienceandTechnology(CCAST) (WorldLab.)P.O.Box8730Beijing100080China

A revised iterative method based on Green function defined by quadratures along a single trajectory is proposed to solve the low-lying quantum wave function for Schro^edinger equation. Specially a new expression of the perturbed energy is obtained, which is much simpler than the traditional one. The method is applied to solve the unharmonic oscillator potential. The revised iteration procedure gives exactly the same result as those based on the single trajectory quadrature method. A comparison of the revised iteration method to the old one is made using the example of Stark effect. The obtained results are consistent to each other after making power expansion.

关键词：量子力学格林函数修订迭代解薛定谔方程单轨道求积法

Mass spectrometry profiling of single bacterial cells reveals metabolic regulation during antibiotics induced bacterial filamentation

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Chinese Chemical Letters 2023年第6期34卷 242-246页

作者： Dongxue Zhang qin qin Liang Qiao Department of Chemistry Institutes of Biomedical Sciencesand Shanghai Stomatological HospitalFudan UniversityShanghai 200000China Changhai Hospital The Naval Military Medical UniversityShanghai 200433China

Bacterial antimicrobial resistance(AMR)is a severe threat to global health and *** the stimulation of antibiotics,bacterial cells can undergo filamentation and generate daughter cells with stronger *** current research on bacterial AMR mechanism is mainly conducted with a population of ***,bacterial cells exhibit heteroresistance,making the study at population level not ***,we developed single bacterial cell metabolic profiling by mass spectrometry(MS)to study bacterial AMR at single-cell *** utilizing a microprobe controlled by a microoperation platform,single filamentous extended spectrum beta-lactamase(ESBL)producing Escherichia coli(***)cells generated by ceftriaxone sodium stimulation can be extracted and spray-ionized for MS *** among *** cells under the same antibiotic stimulus condition was observed from mass spectra as well as cell *** metabolic profiles by MS of different individual cells can be clustered into subgroups well in accordance with bacterial cell *** pathways including arginine and proline metabolism,as well as cysteine and methionine metabolism were disclosed to play an important role in the bacterial SOS-associated filamentation against *** microprobe electrospray ionization-MS-based single bacterial cell analysis method is promising in the study of various bacterial AMR mechanism and can reveal the heterogeneity of bacterial AMR from-cell-to-cell.

关键词： ESI-MS Single bacterial cell analysis Metabolome Bacterial antimicrobial resistance Bacterial filamentation

Instability of Taylor-Couette Flow of Electrorheological Fluid

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Chinese Physics Letters 2004年第7期21卷 1388-1390页

作者： PENGJie ZHUKe-qin DepartmentofEngineeringMechanics TsinghuaUniversityBeijing100084

A linearized instability analysis of Taylor–Couette flow between two rotating concentric cylinders of an electrorheological (ER) fluid is carried out. The ER fluid exhibits a yield stress in addition to the plastic viscosity when an extra electric-field is applied. It can be found that the yield stress plays a dual role in the flow instability. The possibility of the yield surface falling between the cylinders is analysed. Although small waves appeared on the yielded surface is considered, the yielded surface, which has been treated as a free surface, has little effect on the flow instability. The effects of axisymmetric perturbation on the flow instability are presented due to the axisymmetric of the basic flow. The parameter β in the yield stress formula of the ER fluid is shown to have distinct effects on the flow instability characteristics.

关键词： Electrorheological fluids

甘肃省农业绿色全要素生产率测算及影响因素研究

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国土与自然资源研究 2025年第1期 59-65页

作者：秦博范国华甘肃农业大学管理学院兰州730070

提升农业绿色全要素生产率对于实现农业可持续发展具有重要的意义。运用SBM-GML指数法对甘肃省各市州2011-2020年的农业绿色全要素生产率及其区域差异进行分析,最后运用Tobit模型对甘肃省农业绿色全要素生产率影响因素进行分析,并在此... 详细信息

提升农业绿色全要素生产率对于实现农业可持续发展具有重要的意义。运用SBM-GML指数法对甘肃省各市州2011-2020年的农业绿色全要素生产率及其区域差异进行分析,最后运用Tobit模型对甘肃省农业绿色全要素生产率影响因素进行分析,并在此基础上提出相应的对策建议。研究结果显示,(1)甘肃省农业绿色全要素生产率总体呈上升趋势,上升的主要动力来源于技术进步。(2)甘肃省农业绿色全要素生产率存在一定的空间差异性,总体呈现出“西低东高”的分布特点。(3)在甘肃省农业绿色全要素生产率的影响因素中,经济发展水平、城镇化水平、财政支农水平和农业产业结构对甘肃省农业绿色全要素生产率的提升具有显著的正向影响,受灾率对甘肃省农业绿色全要素生产率的提升具有显著的负向影响,且不同区域的农业绿色全要素生产率的影响因素也各不相同。最后,在以上分析的基础上提出了相应的对策建议。

关键词：农业绿色全要素生产率影响因素 SBM-GML指数 Tobit模型

Numerical study on the blocking effect of skin on Flash-Ball Impact and damage assessment

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Defence Technology（防务技术） 2024年第3期33卷 532-545页

作者： Dihua Ouyang Chunwei qin Xiaowen qin Qiantao Zhang Xingyu Liu Xi'an University of Architecture and Technology Xi'an 710055China Analysis and Testing Center Xi'an University of Architecture and TechnologyXi'an 710055China Engineering University of PAP Xi'an 710086China

To explore the response law of non-lethal large-size kinetic energy projectiles to blunt attack on skin tissue,and to evaluate the skin injury characteristics of the attacked personnel and the use safety of kinetic energy *** on the LS-DYNA simulation software,a three-layer skin simulation model and a Flash-Ball rubber bullet model are established,and the force-time and deformation-time biomechanical corridors of the Flash-Ball rubber bullet impacting human skin tissue are *** corridor curve and the energy transfer and diffusion are analyzed and *** safety evaluation of the damage caused by the rubber bullet shooting a human body at different distances is carried out using the empirical formula of the penetration ***,the safe shooting distance is *** results show that the model used in the simulation has a good correlation with the experimental data,its biomechanical corridor characteristics are different from those of conventional vehicle impact and smallsize projectile response *** energy transfer and action time of medium and low-speed impact may cause greater *** fat layer is the largest energy absorption *** minimum safe shooting distance to ensure skin tissue from penetrating damage is 15.8 m,and the limit specific kinetic energy of skin damage is 7.88 J/cm^(2).This study can be extended to the study of biomechanical response law and safety evaluation under the impact of the same type of large kinetic energy projectile,which provides an important theoretical reference for the police to use large kinetic energy projectiles to conduct safe shooting in peacekeeping operations.

关键词： KIPs Blunt strike Biomechanical response Damage analysis

Two-dimensional finite element modeling of seepage-erosion coupled process within unsaturated soil slopes

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Journal of Mountain Science 2022年第2期19卷 446-460页

作者： LEI Xiao-qin Key Laboratory of Mountain Hazards and Surface Process Institute of Mountain Hazards and EnvironmentChinese Academy of SciencesChengdu 610041China Center for Excellence in Tibetan Plateau Earth Sciences Chinese Academy of SciencesBeijing 100101China State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengduSichuan 610059China

Fines migration along with rainfall infiltration is a possible cause of failures of slopes composed of loose *** investigate the intrinsic mechanisms,a rigid mathematical model which can fully capture the multi-phasic and multiphysical process is *** this research,the macro and micro physical phenomena of fines migration process within deposited soil slopes under rainfall infiltration were *** on the mixture theory,a seepage-erosion model for unsaturated erodible soils capable to capture these phenomena mathematically was built based on a rigid theoretical *** model was used to simulate a set of rainfall flume tests involving fines migration phenomena with the finite element *** distinct slope failure modes observed experimentally,which were induced by the soil erosion-deposition properties,can be well reproduced by our numerical *** seepage-erosion coupled process during the rainfall infiltration,as well as the intrinsic mechanism responsible for the slope failures,was illustrated in detail based on the numerical *** was shown that the fines migration process can affect the hydro-mechanical response within unsaturated slopes significantly,and therefore special attention should be paid to those soil slopes susceptible to internal erosion.

关键词： Internal erosion Fines migration Rainfall infiltration Slope stability Finite element method

非货币激励因素对中小学教师工作满意度的影响——基于云贵川渝的调查

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教师教育学报 2025年第1期12卷 106-115页

作者：周琴郭瑜琦西南大学教师教育学院重庆400715

教师工作满意度是影响教师工作效能、促进教师可持续发展的重要因素。研究采用TALIS 2018教师问卷对云贵川渝4个省份的中小学教师展开抽样调查。数据分析显示,该地区教师工作满意度处于较高水平,但内部群体间存在显著性差异。回归分析发... 详细信息

教师工作满意度是影响教师工作效能、促进教师可持续发展的重要因素。研究采用TALIS 2018教师问卷对云贵川渝4个省份的中小学教师展开抽样调查。数据分析显示,该地区教师工作满意度处于较高水平,但内部群体间存在显著性差异。回归分析发现,云贵川渝4省份中小学教师工作满意度受工资薪酬以及其他非货币因素的影响。比较分析发现,云贵川渝初中教师对工资薪酬的接受度高于上海同行,但对社会认可、媒体关注等非货币激励因素的认可程度却低于上海教师,从而使其工作满意度整体水平低于上海。研究认为,坚持教育家精神铸魂强师的同时提升教师工作满意度,需要在巩固提高工资薪酬水平的基础上,进一步从优化教师工作体验、提高教师学历、打通职业晋升渠道、营造尊师重教良好氛围等非货币因素着手,在满足教师内在需求的同时,为加快教育现代化、建设教育强国、办好人民满意的教育提供有力支撑。

关键词：中小学教师工作满意度工资非货币激励双因素理论

Viscosity approximation methods with weakly contractive mappings for nonexpansive mappings

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第10期8卷 1691-1694页

作者： WANG Ya-qin Mathematics and Sciences College Shanghai Normal University Shanghai 200234 China

Let K be a closed convex subset of a real reflexive Banach space E, T：K→K be a nonexpansive mapping, and f：K→K be a fixed weakly contractive （may not be contractive） mapping. Then for any t∈（0, 1）, let x1∈K be the unique fixed point of the weak contraction x1→tf（x）＋（1-t）Tx. If T has a fixed point and E admits a weakly sequentially continuous duality mapping from E to E^＊, then it is shown that {xt} converges to a fixed point of T as t→0. The results presented here improve and generalize the corresponding results in （Xu, 2004）.

关键词： Viscosity approximation methods Weakly contractive mapping Fixed point Weakly sequentially continuous duality mapping