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检索条件"作者=Qimin zhan"
91 条 记 录,以下是1-10 订阅
Exploring the role of microRNAs in tumorigenesis
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Chinese Science Bulletin 2014年 第19期59卷 2221-2222页
作者: qimin zhan Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College
Recent years,one of the most striking findings in the field of biomedical science is the identification of miRNAs,which are small endogenous non-coding transcripts of**** are thought to bind to the complementary sites... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Transcriptional activation of Nlp by estrogen-ERa in breast cancer
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Science Bulletin 2017年 第21期62卷 1445-1454页
作者: jia li jie chen liyan xue qimin zhan State Key Laboratory of Molecular Oncology Cancer Institute and HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBejing 100021China Laboratory of Molecular Oncology Peking University Cancer HospitalBeijing 100142.China Department of Pathology Cancer Institute and HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China
Estrogen Receptor-a (ERa) is the key transcription factor that regulates cell proliferation and homeosta- sis. In this pathway, estrogen plays an important role in genomic instability and cell cycle regulation pro- ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Cdk phosphorylation licenses Kif4A chromosome localization required for early mitotic progression
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Journal of Molecular Cell Biology 2018年 第4期10卷 358-370页
作者: Zhixiong Dong Changjun Zhu qimin zhan Wei Jiang State Key Laboratory of Molecular Oncology National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China Key Laboratory of Molecular and Cellular Systems Biology Tianjin Normal University Tianjin 300387 China Tianjin Key Laboratory of Animal and Plant Resistance College of Life Sciences Tianjin Normal University Tianjin 300387 China
The chromokinesin Kif4A controls proper chromosome condensation, congression/alignment, and cytokinesis to ensure faithful genetic inheritance. Here, we report that Cdk phosphorylation of human Kif4A at T1161 licenses... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Dynamic analysis of DNA damage induced miRNAs in colon cancer cells
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Chinese Science Bulletin 2014年 第19期59卷 2254-2265页
作者: Weimin zhang Fang Yang qimin zhan State Key Laboratory of Molecular Oncology Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Sir Run Run Shaw Hospital (SRRSH) Zhejiang University School of Medicine
It is known that microRNAs(miRNAs)expression profile shows substantial changes in cells under DNA ***,we did miRNA microarray and quantitative real-time PCR to comprehensively identify the differentially expressed miR... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
p53 functional activation is independent of its genotype infive esophageal squamous cell carcinoma cell lines
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Frontiers of Medicine 2010年 第4期4卷 412-418页
作者: Junfang JI Kun WU Min WU qimin zhan State Key Laboratory of Molecular Oncology Cancer InstituteChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China
p53 mutations have been found in many esophageal squamous cell carcinoma(ESCC)clinical specimens and cell *** reasoned that functional inactivation of wild-type p53 or the functional activation of mutant-type p53 migh... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
ZNF292 suppresses proliferation of ESCC cells through ZNF292/SKP2/P27 signaling axis
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Chinese Journal of Cancer Research 2021年 第6期33卷 637-648页
作者: Wei Gong Jiancheng Xu Guangchao Wang Dan Li qimin zhan State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Laboratory of Molecular OncologyPeking University Cancer Hospital&InstituteBeijing 100142China
Objective:Increasing evidence has demonstrated that ZNF292 plays a suppressive role in cancer,however,little is known about its function and exact mechanism in esophageal squamous cell carcinoma(ESCC).Methods:Bioinfor... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings:A positive feedback loop regulation
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Journal of Genetics and Genomics 2017年 第12期44卷 557-565页
作者: Yunwei Ou Qingnan Wu Chuanyue Wu Xuefeng Liu Yongmei Song qimin zhan Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China Beijing Neurosurgical Institute Capital Medical UniversityBeijing 100050China State Key Laboratory of Molecular Oncology National Cancer Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Pathology University of PittsburghPittsburgh 15261USA Department of Biology and Shenzhen Key Laboratory of Cell Microenvironment South University of Science and Technology of ChinaShenzhen 518055China china National Clinical Research Center for Neurological Diseases BeUing 100050China
Glioma is the most common type of primary brain tumors in the central nervous system(CNS). Migfilin occurs in human glioma and enhances cellular motility via the epidermal growth factor receptor(EGFR)pathway. Howe... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Understanding metabolic reprogramming in tumor microenvironment
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Medical Review 2021年 第2期1卷 111-113页
作者: Shaokun Shu Ying Xu qimin zhan Peking University International Cancer Institute Beijing100191China Department of Biochemistry and Molecular Biology and Institute of BioinformaticsUniversity of GeorgiaAthensGAUSA
Cancer ranks as a leading cause of death and is a most important barrier to increasing life expectancy in the *** were estimated 19.3 million new cases and 9.6 million cancer deaths worldwide in *** accounted for 24%o... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Downregulation of miR-503 Promotes ESCC Cell Proliferation,Migration,and Invasion by Targeting Cyclin D1
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Genomics, Proteomics & Bioinformatics 2017年 第3期15卷 208-217页
作者: Lanfang Jiang Zitong Zhao Leilei Zheng Liyan Xue qimin zhan Yongmei Song State Key Laboratory of Molecular Oncology National Cancer Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive cancers in China, but the underlying molecular mechanism of ESCC is still unclear. Involvement of micro- RNAs has been demonstrated in cancer i... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Deregulated expression and subcellular localization of CPSF6,a circRNA-binding protein,promote malignant development of esophageal squamous cell carcinoma
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Chinese Journal of Cancer Research 2022年 第1期34卷 11-27页
作者: Shichao Guo Guangchao Wang Zitong Zhao Dan Li Yongmei Song qimin zhan State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Laboratory of Molecular OncologyPeking University Cancer Hospital&InstituteBeijing 100142China
Objective:Cleavage and polyadenylation specific factor 6(CPSF6)has been documented as an oncoprotein in different types of ***,functions of CPSF6 have not been investigated yet in esophageal squamous cell carcinoma(ES... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论