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Targeted regulation of neuroinflammation via nanobiosignaler for repairing the central nerve system injuries

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Nano Research 2023年第2期16卷 2938-2948页

作者： Xiaoru Sun Huitong Ruan qidong liu Silu Cao Qi Jing Yaru Xu Lize Xiong Wenguo Cui Cheng Li Department of Anesthesiology and Perioperative Medicine Shanghai Fourth People’s HospitalSchool of MedicineTongji UniversityShanghai 200434China Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Translational Research Institute of Brain and Brain-Like Intelligence Shanghai Fourth People’s HospitalSchool of MedicineTongji UniversityShanghai 200434China Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation Shanghai 200434China

Neuroinflammation,commonly associated with various central nervous system(CNS)diseases such as postoperative cognitive dysfunction(POCD),is primarily mediated by the disruption of biological signals in ***,the effective treatment of CNS diseases remains an ongoing challenge as biological signals show limited microglia-targeting *** this study,taking advantage of the highly expressed lipoprotein receptor-related protein-1(LRP1)on the microglia,a nanobiosignal delivery system modified by LRP1 high-affinity peptide ligand RAP12(RAP:receptor-associated protein)was constructed to specifically regulate neuroinflammation via targeting *** uptake of the RAP12 modified-nanobiosignaler by microglia increased significantly,indicating its microglia-targeting *** in vitro/vivo studies proved that the“nanobiosignaler”significantly reduced the secretion of pro-inflammatory cytokines,induced specific M2(anti-inflammatory type)microglia differentiation,and remarkably alleviated cognitive function impairment in the mice model when compared with unmodified *** was indicated that the“nanobiosignaler”could target microglia to deliver the biological signal and inhibit the excessive activation of ***,the cell-targeted biological signal transmission system inspired by“nanobiosignaler”has broad application prospects in the future.

关键词： biosignal nanoparticles microglia neuroinflammation targeted delivery

Selective growth of semiconducting single-walled carbon nanotubes solely from carbon monoxide

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Nano Research 2023年第11期16卷 12720-12726页

作者： Xue Zhao Ningfei Gao Zeyao Zhang qidong liu Jian Sheng Yijie Hu Ruoming Li Haitao Xu Lianmao Peng Yan Li Beijing National Laboratory for Molecular Sciences Key Laboratory for the Physics and Chemistry of NanodevicesState Key Laboratory of Rare Earth Materials Chemistry and ApplicationsCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China Beijing HuaTanYuanXin Electronics Technology Ltd.Co. Beijing 101399China Institute of Carbon-Based Thin Film Electronics Peking UniversityShanxiTaiyuan 030012China Institute of Advanced Functional Materials and Devices Shanxi UniversityTaiyuan 030031China PKU-HKUST ShenZhen-HongKong Institution Shenzhen 518057China

The selective growth of semiconducting single-walled carbon nanotubes(s-SWCNTs)is of great importance in many high-end applications represented by ***,we developed a general approach to grow horizontally aligned s-SWCNT arrays on stable temperature(ST)-cut quartz with bimetallic catalysts using carbon monoxide(CO)as both catalyst reductant and single component carbon feedstock under atmospheric *** disproportionation of CO produces not only carbon species for SWCNT growth but also CO_(2),which could act as an in-situ etchant to remove both amorphous carbon and metallic *** employment of bimetallic catalyst and quartz substrate facilitates the selective etching by narrowing the diameter distribution of as-grown SWCNT *** the optimized conditions,we realized the selective growth of horizontally aligned s-SWCNT arrays with the content above 97%using CoCu catalysts,confirmed by Raman characterization and electrical measurements of the fabricated field effect transistor *** CO-based process in selective growth of s-SWCNTs has demonstrated its feasibility and universality by the broad growth window and applicability for other bimetallic catalysts,such as FeCu and *** possesses a practical potential in obtaining semiconducting channel materials for the scalable fabrication of CNT-based devices.

关键词： carbon monoxide semiconducting single-walled carbon nanotubes arrays bimetallic catalysts

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基于卷积神经网络的风机叶片损伤检测

热力发电 2023年第3期52卷 88-93页

作者：刘启栋青海黄河风力发电有限责任公司青海海南813000

作为捕获风能的关键部件,风机叶片受制造及运行载荷影响,可能存在不同程度的损伤,这会直接影响风机运行可靠性。为防止风机叶片持续损伤发生质量安全事故,需要开发1种快速简便且非植入安装式的检测方法来识别风机叶片的损伤情况。根据... 详细信息

作为捕获风能的关键部件,风机叶片受制造及运行载荷影响,可能存在不同程度的损伤,这会直接影响风机运行可靠性。为防止风机叶片持续损伤发生质量安全事故,需要开发1种快速简便且非植入安装式的检测方法来识别风机叶片的损伤情况。根据叶片损伤和叶片运行噪声间存在的物理相关性,提出了一种基于声学信号和卷积神经网络(convolutional neural network,CNN)的风机叶片损伤检测方法,将时序声学信号转换成二维频谱图片,结合健康频谱图生成残差频谱图,并通过训练卷积神经网络来识别风机叶片是否存在损伤。分析结果表明:该算法消除了叶轮旋转产生的固有叶片扫风声音对损伤识别的影响,提高了识别精度;以某地风机的实测数据为例进行算法分析,结果表明该算法的分类精度达到了96.9%,验证了基于卷积神经网络的检测方法的有效性和精确性。

关键词：风机叶片损伤检测声信号卷积神经网络

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Carbon-Involved Near-Surface Evolution of Cobalt Nanocatalysts:An in Situ Study

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CCS Chemistry 2021年第11期3卷 154-167页

作者： Feng Yang Haofei Zhao Wu Wang qidong liu Xu liu Yuecong Hu Xinrui Zhang Sheng Zhu Dongsheng He Yingying Xu Jiaqing He Rongming Wang Yan Li Beijing National Laboratory for Molecular Science Key Laboratory for the Physics and Chemistry of NanodevicesState Key Laboratory of Rare Earth Materials Chemistry and ApplicationsCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871 Department of Chemistry Guangdong Provincial Key Laboratory of Catalytic ChemistrySouthern University of Science and TechnologyShenzhenGuangdong 518055 Beijing Advanced Innovation Center for Materials Genome Engineering Center for Green InnovationBeijing Key Laboratory for Magneto-Photoelectrical Composite and Interface ScienceSchool of Mathematics and PhysicsUniversity of Science and Technology BeijingBeijing 100083 Department of Physics Southern University of Science and TechnologyShenzhenGuangdong 518055 Core Research Facilities Southern University of Science and TechnologyShenzhenGuangdong 518055

When carbon-containing species are involved in reactions catalyzed by transition metals at high temperature,the diffusion of carbon on or in catalysts dramatically influences the catalytic *** information on the carbon-diffusioninvolved evolution of catalysts at the atomic level is crucial for understanding the reaction mechanism yet also *** the chemical vapor deposition process of single-walled carbon nanotubes(SWCNTs),we recorded in situ the catalyst state(solid and molten)composition as well as near-surface structural and chemical evolution at the cobalt catalyst-tube interface with carbon permeation using aberration-corrected environmental transmission electron microscopy and synchrotron X-ray absorption *** nucleation of SWCNTs was linked with an alternating dissolving and precipitating cycle of carbon in catalysts close to the nucleation *** the dynamics of carbon atoms in catalysts brings deeper insight into the growth mechanism of SWCNTs and facilitates inferring mechanisms of other *** methodologies developed here will find broad applications in studying catalytic and other processes.

关键词： carbon nanotube catalysts chemical vapor deposition structure evolution aberrationcorrected environmental transmission electron microscopy

Ultrafast fiber laser based on gold nanoparticle supported on carbon black saturable absorber

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Optoelectronics Letters 2024年

作者： JI Yubo WANG Zhenyu YANG Yatao liu qidong DU Geguo College of Electronics and Information Engineering， Shenzhen University Beijing Wedge System Company Limited

Due to their unique physical properties， nonlinear materials are gradually demonstrating significant potential in the field of optics. Gold nanoparticles supported on carbon black (Au/CB) ， possessing low loss and high nonlinear characteristics， serves as an excellent material for saturable absorbers (SA) in ultrafast fiber lasers. In this study， we investigated the performance of Au/CB material and designed an ultrafast fiber laser based on Au/CB SA， successfully observing stable fundamental mode-locking and pulse bunch phenomena. Specifically， when the fiber laser operates in fundamental mode-locking state， the center wavelength of optical spectrum is 1558.82 nm， with a 3dB bandwidth of 2.26 nm. Additionally， to investigate the evolution of real-time spectra， the dispersive Fourier transform (DFT) technology is employed. On the other hand， the pulse bunch emitted by the laser is actually composed of numerous random sub-pulses， exhibiting high-energy characteristics. The number of sub-pulses increases with the increase in pump power. These findings contribute to further exploring the properties of Au/CB material and reveal its potential applications in ultrafast optics.

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牛仔服装清洗废水的处理

工业水处理 2007年第2期27卷 66-68页

作者：刘启东陕西科技大学资源与环境学院陕西西安710021

介绍了以水解酸化—接触氧化为主体的工艺处理牛仔服装清洗废水的工程实例,包括工艺选择、主要单元说明、主要设备与构筑物以及工程的经济和社会效益分析。

关键词：水解酸化接触氧化牛仔服装清洗废水

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Ability of lower teardrop edge to restore anatomical hip center height in total hip arthroplasty

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Chinese Medical Journal 2014年第22期127卷 3915-3920页

作者： Lu Yufeng Cheng Liming Guo Wanshou Yu Qingsheng Gao Fuqiang Zhang qidong liu Zhaohui Sun Wei Shi Zhencai Department of Bone and Joint Surgery China-Japan Friendship Hospital Beijing 100029 China

Background The acetabular teardrop is often used to guide acetabular component placement in total hip arthroplasty （THA）.Placing the lower acetabular component aspect at the same level as the lower teardrop edge was assumed to restore the hip center of *** we radiographically analyzed the relationship between cup center and normal contralateral acetabulum center height on unilateral THA using this placement *** A total of 106 unilateral THA cases with normal contralateral acetabula were reviewed and the vertical and horizontal distances in relation to the lower acetabular teardrop edge from both hip joint centers,cup inclination,and anteversion were measured *** paired t-test was used to compare left and right hip center *** plots and Pearson＇s correlation coefficients were used to evaluate differences in hip center heights,cup anteversion,inclination angles,and medialized cup center distance compared to the contralateral hip *** Cup center height was significantly greater （P ＜0.01） than contralateral hip joint center height （93.4％ in the 0-5 mm range,6.6％＞5 mm）.There was a weak correlation between hip center height difference and inclination （r=0.376,P ＜0.01） and between difference and anteversion （r=0.310,P ＜0.01） but no correlation between difference and outer cup diameter （r=0.184,P=0.058） or difference and medialized cup center distance （r＝-0.098,P=0.318）.Conclusions Although this method did not exactly replicate anatomic hip center height,the clinical significance of cup center height and anatomic hip center height differences is *** acetabular component placement method has high simplicity,reliability,and stability.

关键词： total hip arthroplasty teardrop hip center height inclination anteversion

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Preparation and Characterization of MnOX -CeO2/TiO2 Catalytic Material for SCR of NOX with NH3 at Low Temperature

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Preparation and Characterization of MnOX -CeO2/TiO2 Catalyti...

中国材料大会2012

作者： qidong liu Suping Cui Hongxia Guo Yali Wan Yunfeng Zhang The College of Materials Science and Engineering Beijing University of Technology

ISBN: (纸本)9783037856062

The MnOX-CeO2/TiO2 catalytic material for low temperature SCR of NOX with NH3 was prepared using aqueous solutions of three manganese salt as well as cerous nitrate and TiO2 （anatase） powder by impregnation method. The properties of the catalytic materials were investigated by TG-DSC, XRF, XRD, XPS, BET and SEM. And the low temperature catalytic activity of the catalytic materials was measured. The results showed that, when manganese nitrate and manganese chloride and manganese acetate were used as precursors, respectively, the primary phases of catalytic materials were MnOx/MnO2 , MnO2 /Mn8O10 Cl3 and Mn3O4/MnO2 , the surface Mn/Ti molar ratio were 0.68, 0.19 and 0.88, the surface area were 45.1m2/g, 25.1 m2/g and 48.6 m2/g ,respectively. The optimum NOX conversion rate of catalytic material from manganese nitrate precursor and manganese chloride precursor and manganese acetate precursor were 97.9% at 483K, 86.6% at 513K, 97.2% at 423K, respectively. Consequently, the higher low-temperature activity of MnOX-CeO2/TiO2 from manganese acetate precursor may be attributed to higher surface and higher surface concentration of activity component.

关键词： Low-temperature SCR MnOX -CeO2/TiO2 Catalytic material NO conversion.

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汽车涂装废水处理系统的优化

环境工程 2005年第1期23卷 23-24页

作者：刘启东陕西科技大学资源环境学院咸阳712081

通过对重庆某汽车制造厂涂装车间原废水处理工艺运行状况的调查 ,分析出该废水处理运行中存在的主要问题是 :废水水量与水质很不稳定 ;相同的处理方法加大了对不同废水的处理难度 ;设备腐蚀较为严重。改造后的处理工艺 ,对不同的废水先... 详细信息

通过对重庆某汽车制造厂涂装车间原废水处理工艺运行状况的调查 ,分析出该废水处理运行中存在的主要问题是 :废水水量与水质很不稳定 ;相同的处理方法加大了对不同废水的处理难度 ;设备腐蚀较为严重。改造后的处理工艺 ,对不同的废水先进行不同的物化处理 ,然后进入SBR反应器进一步进行生化处理 ,并且在设备的预制时就采取了一系列的防腐措施 ,很好地解决了原处理工艺中存在的问题。

关键词：废水处理系统废水处理工艺 SBR反应器生化处理物化处理水质水量汽车涂装汽车制造厂预制

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