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Effects of Bivalirudin and Unfractionated Heparin on Liver and Renal Function in Chinese Patients with Coronary Artery Disease Undergoing Coronary Angiography with/without Percutaneous Coronary Intervention

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Journal of Clinical and Translational Hepatology 2021年第4期9卷 477-483页

作者： qiaowei jia jia Hu Wenfeng Ji Liansheng Wang Enzhi jia Department of Cardiovascular Medicine First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Department of Cardiovascular Medicine Liyang People’s HospitalLiyangJiangsuChina

Background and Aims:Unfractionated heparin(UFH)and bivalirudin are widely used as anticoagulants in cardiovascular medicine,including for thrombosis prevention during coronary angiography(CAG)and percutaneous coronary intervention(PCI).Little is known of the effects of UFH and bivalirudin on liver and kidney function in patients subjected to these procedures.This study compared the effects of bivalirudin and UFH on liver/renal function in patients with coronary artery disease who underwent CAG,with or without PCI.Methods:The study comprised 134 consecutive patients(40–89 years-old),who underwent CAG(or CAG and PCI);among them,66 and 68 patients were subject to,respectively,bivalirudin or UFH.The following indicators of liver/renal function were measured before and after the procedures:plasma alanine aminotransferase(ALT),aspartate aminotransferase(AST),blood urea nitrogen,estimated glomerular filtration rate(eGFR),creatinine clearance,and serum creatinine.Patients were further stratified by severity of chronic kidney disease(CKD),based on original eGFR.Results:Relative to baseline,in the bivalirudin group,ALT and AST were higher after CAG(p=0.005,0.025),while blood urea nitrogen and serum creatinine were lower(p=0.049,<0.001).In the UFH group,ALT,AST,eGFR,and creatinine clearance were lower after CAG(p≤0.001,all).Patients given bivalirudin with moderate or severe CKD,but not those with mild CKD,gained significant improvement in kidney function.Conclusions:Relative to UFH,bivalirudin may better safeguard the renal function of patients with coronary artery disease who undergo CAG,especially patients with moderate-to-severe renal insufficiency.UFH may cause less liver damage than bivalirudin.

关键词： Bivalirudin Unfractionated heparin Coronary artery disease Coro-nary angiography Percutaneous coronary intervention Liver function

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Sieving carbons promise practical anodes with extensible low-potential plateaus for sodium batteries

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National Science Review 2022年第8期9卷 118-126页

作者： Qi Li Xiangsi Liu Ying Tao jianxing Huang Jun Zhang Chunpeng Yang Yibo Zhang Siwei Zhang Yiran jia qiaowei Lin Yuxuan Xiang Jun Cheng Wei Lv Feiyu Kang Yong Yang Quan-Hong Yang Nanoyang Group State Key Laboratory of Chemical EngineeringSchool of Chemical Engineering and TechnologyTianjin University Nanoyang Group Joint School of National University of Singapore and Tianjin UniversityInternational Campus of Tianjin University Haihe Laboratory of Sustainable Chemical Transformations State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials and Department of ChemistryCollege of Chemistry and Chemical EngineeringXiamen University Shenzhen Key Laboratory for Graphene-Based Materials Engineering Laboratory for Functionalized Carbon MaterialsTsinghua Shenzhen International Graduate SchoolTsinghua University

Non-graphitic carbons are promising anode candidates for sodium-ion batteries, while their variable and complicated microstructure severely limits the rational design of high-energy carbon anodes that could accelerate the commercialization of sodium-ion batteries, as is the case for graphite in lithium-ion batteries.Here, we propose sieving carbons, featuring highly tunable nanopores with tightened pore entrances, as high-energy anodes with extensible and reversible low-potential plateaus(<0.1 V). It is shown that the tightened pore entrance blocks the formation of the solid electrolyte interphase inside the nanopores and enables sodium clustering to produce the plateau. Theoretical and spectroscopic studies also show that creating a larger area of sodiophilic pore surface leads to an almost linearly increased number of sodium clusters, and controlling the pore body diameter guarantees the reversibility of sodium cluster formation,producing a sieving carbon anode with a record-high plateau capacity of 400 mAh g–1. More excitingly, this approach to preparing sieving carbons has the potential to be scalable for modifying different commercial porous carbons.

关键词： sodium-ion batteries sieving carbons low-potential plateau pore entrance diameter pore surface area

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A Triptycene-Based Porous Organic Polymer that Exhibited High Hydrogen and Carbon Dioxide Storage Capacities and Excellent CO_(2)/N_(2) Selectivity

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中国化学:英文版 2015年第5期33卷 539-544页

作者： Xi-Long Lu Tian-You Zhou Doufeng Wu Qiang Wen Xin Zhao qiaowei Li Qun Xiang jia-Qiang Xu Zhan-Ting Li Department of Chemistry Shanghai UniversityShanghai 200444China Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China Department of Chemistry Fudan UniversityShanghai 200433China

A novel porous organic polymer(POP)has been constructed through the condensation of triptycene tricatechol and 1,3,5-benzenetris(4-phenylboronic acid).This triptycene-based POP exhibited high H2 uptake(up to 1.84 wt%at 77 K,1 bar),large CO_(2) adsorption capacity(up to 18.1 wt%at 273K,1 bar),and excellent CO_(2)/N_(2) adsorption selectivity(up to 120/1).The influence of solvent on the gas adsorption performance of the POP has also been investigated.

关键词： porous organic polymers H_(2)/CO_(2)adsorption CO_(2)/N_(2)selectivity

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一种适用于同塔双回线路的双端故障测距方法

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云南电力技术 2021年第2期49卷 11-14,18页

作者：石恒初卢佳杨远航杨桥伟游昊赵明解良朱青成云南电力调度控制中心昆明650011 云南电网有限责任公司电力科学研究院昆明650217

利用故障录波全量信息的双端测距方法,方法简单可靠,但算法使用了零序分量,测距结果受零序阻抗误差以及零序分量偏差的影响。本文提出一种利用故障正、负序分量的输电线路两侧故障录波测距方法,依据线路两侧同步采集得到的三相故障电压... 详细信息

利用故障录波全量信息的双端测距方法,方法简单可靠,但算法使用了零序分量,测距结果受零序阻抗误差以及零序分量偏差的影响。本文提出一种利用故障正、负序分量的输电线路两侧故障录波测距方法,依据线路两侧同步采集得到的三相故障电压、电流分解出正、负序分量,利用正、负序分量开展双端测距,消除零序分量影响,并提出了滑窗计算测距的具体方法,进一步提高测距精度。该方法较全量测距算法稍显复杂,但从原理上消除了同塔线路互感对测距结果的影响,使得测距结果更加准确,可作为全量测距算法的有益补充。以某一线路单相故障为例对同步方法进行验证。

关键词：数据同步数据窗正负序分量数据处理

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