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公共政策社会影响评估的价值观变革与方法论创新

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江苏社会科学 2024年第2期 103-111,I0004页

作者：陈琛施国庆中国海洋大学国际事务与公共管理学院河海大学公共管理学院

党的十八大以来,党中央高度重视科学决策、民主决策,公共政策评估研究和实践进入快速发展阶段。自第四代评估的概念提出之后,公共政策的外溢效应评估即社会影响评估在国际上呈现三种发展趋势:建构主义、民主协商与伦理约束。从价值观视... 详细信息

党的十八大以来,党中央高度重视科学决策、民主决策,公共政策评估研究和实践进入快速发展阶段。自第四代评估的概念提出之后,公共政策的外溢效应评估即社会影响评估在国际上呈现三种发展趋势:建构主义、民主协商与伦理约束。从价值观视角剖析,三者体现为科学主义与实证主义反思所引领的本体论与认识论的变革;从方法论视角审视,三者体现为多元主体治理与解释学辩证所代表的创新趋势。新趋势是科学化与民主化两种倾向博弈的结果,具体表现为经过管理学派与参与学派近二十年来的争论,后者逐渐取代前者成为主流。对我国而言,社会影响评估理论的引介既符合关口前移的风险治理思路,也从公众参与视角丰富了社会治理的工具箱,有助于提高我国决策的民主性和科学性。

关键词：政策评估社会影响评估建构主义社会责任社会风险

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Influence of extraction voltage on electron and ion behavior characteristics

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Chinese Physics B 2024年第4期33卷 553-559页

作者：徐翱甘娉娉石元杰陈磊 Institute of Electronic Engineering China Academy of Engineering PhysicsMianyang 621999China

The characteristics of the extracted ion current have a significant impact on the design and testing of ion source *** this paper,a 2D in space and 3D in velocity space particle in cell(2D3V PIC)method is utilized to simulate plasma motion and ion extraction characteristics under various initial plasma velocity distributions and extraction voltages in a Cartesian coordinate *** plasma density is of the order of 10^(15)m^(-3)-10^(16)m^(-3)and the extraction voltage is of the order of 100 V-1000 *** study investigates the impact of various extraction voltages on the velocity and density distributions of electrons and positive ions,and analyzes the influence of different initial plasma velocity distributions on the extraction *** simulation results reveal that the main reason for the variation of extraction current is the spacecharge force formed by the relative aggregation of positive and negative net *** lays the foundation for a deeper understanding of extraction beam characteristics.

关键词： extraction voltage plasma ion beam ion current

社会政策助推新质生产力:内在逻辑、现实挑战与实践路径

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社会科学战线 2024年第6期 254-262页

作者：陈仁兴陈钊山东大学政治学与公共管理学院山东青岛266237 南京大学政府管理学院江苏南京210023

新质生产力是高质量发展的内在要求和重要着力点。社会政策作为生产关系的重要构成,可以有效助推新质生产力发展。社会政策与新质生产力之间呈现一种“互嵌式”发展关系。一方面,社会政策通过发挥“助推器”“稳定器”和“安全阀”的作... 详细信息

新质生产力是高质量发展的内在要求和重要着力点。社会政策作为生产关系的重要构成,可以有效助推新质生产力发展。社会政策与新质生产力之间呈现一种“互嵌式”发展关系。一方面,社会政策通过发挥“助推器”“稳定器”和“安全阀”的作用,为新质生产力发展奠定坚实的制度基础;另一方面,新质生产力为社会政策适应性调整和持续性优化提供重要契机。与此同时,新质生产力发展可能衍生的新型风险对社会政策提出了诸多挑战,社会政策体系的碎片化、回应滞后性以及再分配能力不足等问题制约其助推新质生产力发展功能的发挥。社会政策助推新质生产力发展,需遵循社会公民身份与需要本位的社会政策价值理念、坚持发展型社会政策导向、构建系统整合的社会政策体系、提升社会政策福利治理能力,全面推进新质生产力协同性、包容性发展。

关键词：新质生产力社会政策高质量发展社会风险福利治理

Effect of Sintering Temperature on the Microstructure and Mechanical Properties of Nanocrystalline Cemented Carbide

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 664-672页

作者：陈先富刘颖 YE Jinwen WANG Lu School of Materials Science and Engineering Sichuan UniversityChengdu 610065China Key Laboratory of Advanced Special Ma-terial&Technology Ministry of EducationChengdu 610065China

WC-Co nanocrystalline nitrogen-containing cemented carbides were prepared by vacuum sintering and low pressure *** sintering processes of Cr_(2)(C,N)doped nano WC-Co powders were studied by using thermogravimetric analysis(TGA)and differential scanning calorimetry(DSC).The effect of sintering temperature on the microstructure and mechanical properties of nanocrystalline cemented carbide was studied by scanning electron microscope(SEM),high resolution transmission electron microscope(HRTEM)and mechanical property *** results showed that the nano WC grains began to grow in the solid phase sintering stage.A high-performance nano-nitrogen-containing cemented carbide with uniform microstructure and good interfacial bonding can be obtained by increasing the sintering temperature to 1380℃.It has a transverse rupture strength(TRS)of 5057 MPa and a hardness of 1956 HV30.

关键词： nano nitrogen cemented carbide sintering temperature microstructure mechanical properties

An overview of pigment gland morphogenesis and its regulatory mechanism

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Journal of Cotton Research 2024年第2期7卷 207-214页

作者： SUN Yue YANG Ping HAN Yifei LI Huazu SUN Deli chen Jinhong ZHU Shuijin ZHAO Tianlun College of Agriculture and Biotechnology Zhejiang UniversityHangzhou 310058China Agricultural Experiment Station Zhejiang UniversityHangzhou 310058China Institute of Hainan Zhejiang UniversitySanyaHainan 572025China

Cotton has enormous economic potential,providing high-quality protein,oil,and *** the comprehensive utilization of cottonseed is limited by the presence of pigment gland and its *** gland is a common characteristic of Gossypium genus and its relatives,appearing as visible dark opaque dots in most tissues and organs of cotton *** metabolites,such as gossypol,synthesized and stored in the cavities of pigment glands act as natural phytoalexins,but are toxic to humans and other monogastric ***,only a few cotton genes have been identified as being associated with pigment gland morphogenesis to date,and the developmental processes and regulatory mechanism involved in pigment gland formation remain largely ***,the research progress on the process of pigment gland morphogenesis and the genetic basis of cotton pigment glands is reviewed,for providing a theoretical basis for cultivating cotton with the ideal pigment gland trait.

关键词： Cotton Pigment gland morphogenesis Transcriptional regulation Terpenoids biosynthesis

C—F Bond Insertion into Indoles with CHBr_(2)F:An Efficient Method to Synthesize Fluorinated Quinolines and Quinolones

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Chinese Journal of Chemistry 2024年第10期42卷 1128-1132页

作者： Chao Li Lei chen Hongye Wang Zixi Yan Bin Lyu Weiping Lyu Changwei Jiang Dehua Lu Jiaxing Li Ning Jiao Song Song State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityXue Yuan Rd.38Beijing 100191China

A mild and practical method for synthesizing fluorinated quinoline derivatives,which have a wide range of applications in pharmaceuticals,materials,and organic synthesis,was described through C—F bond insertion into indoles using CHBr_(2)*** simple conditions,readily availability of CHBr_(2)F,as well as the versatility of the transformations make this strategy very powerful in synthesizing 3-fluoroquinoline and *** mechanistic studies reveal that bromofluorocarbene generated in-situ under basic condition was the key intermediate.

关键词： Skeleton edit Fluorocarbene Ring expansion Quinoline Quinolone

MACF1 deficiency suppresses tooth mineralization through IGF1 mediated crosstalk between odontoblasts and ameloblasts

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Genes & Diseases 2024年第5期11卷 9-12页

作者： Wuxia Qiu Xiao Lin Shaoqing Yang Zhihao chen Kewen Zhang Chaofei Yang Yu Li Zhiping Miao Xiaoni Deng Xiaohong Duan Airong Qian Lab for Bone Metabolism Xi’an Key Laboratory of Special Medicine and Health EngineeringKey Lab for Space Biosciences and BiotechnologyResearch Center for Special Medicine and Health Systems EngineeringNPU-UAB Joint Laboratory for Bone MetabolismSchool of Life SciencesNorthwestern Polytechnical UniversityXi’anShaanxi 710072China State Key Laboratory of Military Stomatology National Clinical Research Center for Oral DiseasesDepartment of Oral BiologyClinic of Oral Rare and Genetic DiseasesSchool of StomatologyThe Fourth Military Medical UniversityXi’anShaanxi 710032China School of Chemical Engineering Sichuan University of Science&EngineeringZigongSichuan 643000China Research&Development Institute of Northwestern Polytechnical University in Shenzhen ShenzhenGuangdong 518063China Puyang Institute of Technology Henan UniversityPuyangHenan 457000China

Tooth mineralization is a ubiquitous and tightly regulated process involving complicated interactions between dental epithelium and *** molecules in tooth mineralization remain poorly *** actin cross-linking factor 1(MACF1)is a spectraplakin protein that plays pivotal roles in the brain,muscle,lung,and bone developmental process.1e3 To study the specific functions of MACF1 in bone formation,we established Macf1 conditional knockout mice using the Cre-LoxP system driven by Osxterix promoter(Osx-Cre;Macf1f/f).2 Not surprisingly,Osx-Cre;Macf1f/f mice displayed the phenotypes of delayed ossification and decreased bone ***,the OsxCre;Macf1f/f mice unexpectedly showed a white and opaque appearance of incisors,contrary to the normal yellowbrown and transparent *** Osxterix is expressed in dental mesenchyme during tooth development,the abnormal tooth appearance might imply a new function of MACF1 in odontoblasts,or even ***,the present study aimed to investigate the role of MACF1 during tooth development.

关键词： mineralization linking transparent

Host cyclophilin A facilitates SARS-CoV-2 infection by binding and stabilizing spike on virions

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Signal Transduction and Targeted Therapy 2024年第1期9卷 36-39页

作者： Xiangpeng Sheng Fang Zhu Hong Peng Fan Yang Yi Yang Cong Yang Zhen Wang Wei chen Deyin Guo Ronggui Hu State Key Laboratory of Molecular Biology Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghaiChina MOE Key Laboratory of Tropical Disease Control Centre for Infection and Immunity StudySchool of MedicineSun Yat-sen UniversityShenzhenChina ICU Longhua Hospital Shanghai University of Traditional Chinese MedicineShanghaiChina

Dear Editor,The novel coronavirus SARS-CoV-2 rapidly evolutes to increase its infectivity and transmissibility,facilitates its immune escape,impairs vaccine efficacy,and currently causes repeated infections in human,which is mainly determined by the accumulated mutations in spike(S).1 Transmembrane S is a heavily glycosylated protein on the surface of the virion as homotrimer,responsible for binding to human angiotensin-converting enzyme 2(hACE2)receptor.2 While the architecture of S trimers has been well studied,how the stability of S is regulated by potential host factors remains unknown.

关键词： ACE2 vaccine infection

A Cross-matching Service for Data Center of Xinjiang Astronomical Observatory

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Research in Astronomy and Astrophysics 2024年第1期24卷 119-127页

作者： Hai-Long Zhang Jie Wang Xin-chen Ye Wan-Qiong Wang Jia Li Ya-Zhou Zhang Xu Du Han Wu Ting Zhang Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Key Laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China National Astronomical Data Center Beijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Cross-matching is a key technique to achieve fusion of multi-band astronomical catalogs. Due to different equipment such as various astronomical telescopes, the existence of measurement errors, and proper motions of the celestial bodies, the same celestial object will have different positions in different catalogs, making it difficult to integrate multi-band or full-band astronomical data. In this study, we propose an online cross-matching method based on pseudo-spherical indexing techniques and develop a service combining with high performance computing system(Taurus) to improve cross-matching efficiency, which is designed for the Data Center of Xinjiang Astronomical Observatory. Specifically, we use Quad Tree Cube to divide the spherical blocks of the celestial object and map the 2D space composed of R.A. and decl. to 1D space and achieve correspondence between real celestial objects and spherical patches. Finally, we verify the performance of the service using Gaia 3 and PPMXL catalogs. Meanwhile, we send the matching results to VO tools-Topcat and Aladin respectively to get visual results. The experimental results show that the service effectively solves the speed bottleneck problem of crossmatching caused by frequent I/O, and significantly improves the retrieval and matching speed of massive astronomical data.

关键词： virtual observatory tools astronomical databases:miscellaneous catalogs