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Acta Mathematicae Applicatae Sinica 2010年第1期26卷 113-124页

作者： qiao-shu zhou Da-qing Jiang Yu Tian Editorial Department of Changchun Normal University Changchun 130032 China School of Mathematics and Statistics Northeast Normal University Changchun 130024 China

This paper deals with the existence and multiplicity of positive solutions to second order period boundary value problems with impulse effects. The proof of our main results relies on a well-known fixed point theorem in cones. The paper extends some previous results and reports some new results about impulsive differential equations.

关键词： Multiple positive solution periodic boundary value problem fixed point theorem in cones Green's function

Co/Co_(7)Fe_(3)heterostructures with controllable alloying degree on carbon spheres as bifunctional electrocatalyst forrechargeable zinc-air batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 476-487页

作者： Junkang Chen Yongyue Zhuang Yanxin qiao Yu Zhang Aihua Yuan Hu zhou School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

Exploring efficient and nonprecious metal electrocatalysts of oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)is crucial for developing rechargeable zinc-air batteries(ZABs).Herein,an alloying-degree control strategy was employed to fabricate nitrogen-doped carbon sphere(NCS)decorated with dual-phase Co/Co_(7)Fe_(3)heterojunctions(CoFe@NCS).The phase composition of materials has been adjusted by controlling the alloying *** optimal CoFe_(0.08)@NCS electrocatalyst displays a half-wave potential of 0.80 V for ORR and an overpotential of 283 mV at 10 mA·cm^(-2)for OER in an alkaline *** intriguing bifunctional electrocatalytic activity and durability is attributed to the hierarchically porous structure and interfacial electron coupling of highly-active Co_(7)Fe_(3)alloy and metallic Co *** the CoFe_(0.08)@NCS material is used as air-cathode catalyst of rechargeable liquid-state zinc-air battery(ZAB),the device shows a high peak power-density(157 mW·cm^(-2))and maintains a stable voltage gap over 150 h,outperforming those of the benchmark(Pt/C+RuO_(2))-based *** particular,the as-fabricated solid-state flexible ZAB delivers a reliable compatibility under different bending *** work provides a promising strategy to develop metal/alloy-based electrocatalysts for the application in renewable energy conversion technologies.

关键词： bifunctional electrocatalysts oxygen reduction reaction oxygen evolution reaction zinc-air battery metal/alloy carbon sphere

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang zhou Ting Li Wei Zhang Jian Wu Hui Hong Wei Quan Xinyu qiao Chun Cui Chenmeng qiao Weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

The protection of beta-carotene against gamma radiation

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The protection of beta-carotene against gamma radiation

The 5th Congress of Toxicology in Developing Countries

作者： Yi-Lan Li, Shan-Shan qiao, Lei zhou, shu-Qing Jiang, Jie Dong Tianjin Centers for Disease Control and Prevention, Hualong Street 76, Hedong District, Tianjin 300011, China

To study the anti-radiation effect of beta-carotene (β-C), different doses of β-C (30, 60 and 90 mg/kg) were orally administered to three separate groups of mice, accompanied by a control group. After the four groups were fed with β-C for 30 days, the mice were exposed to 8.0Gy of Co-γ-radiation and the survival rates over 30 days

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光果翠雀的止血镇痛作用

中国医院药学杂志 2010年第11期30卷 898-900页

作者：费改顺贾正平乔树洲李茂星盛杰兰州军区兰州总医院甘肃兰州730050

目的:研究光果翠雀的止血、镇痛作用。方法:采用兔耳动脉切割止血法及后肢肌肉切割止血法,以云南白药为阳性对照药,用光果翠雀根粉及其水提物、醇提物外敷出血部位进行止血作用研究;分别采用热板法和醋酸扭体法,以对乙酰氨基酚为阳性对... 详细信息

目的:研究光果翠雀的止血、镇痛作用。方法:采用兔耳动脉切割止血法及后肢肌肉切割止血法,以云南白药为阳性对照药,用光果翠雀根粉及其水提物、醇提物外敷出血部位进行止血作用研究;分别采用热板法和醋酸扭体法,以对乙酰氨基酚为阳性对照药研究光果翠雀水提物、醇提物的镇痛作用。结果:光果翠雀粉对兔耳动脉切割后及肌肉切割的止血作用优于云南白药(P<0.05),其水提物、醇提物也有一定的止血作用;水提物、醇提物能显著提高小鼠的热板痛阈,对醋酸引起的小鼠扭体反应具有显著的抑制作用,其镇痛效果与对乙酰氨基酚相当。结论:光果翠雀具有良好的止血镇痛作用。

关键词：光果翠雀止血镇痛作用光果翠雀提取物

不同海拔高度军人气道高反应性咳嗽症候特点分析

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中华中医药杂志 2014年第8期29卷 2466-2468页

作者：乔树洲张印李绍旦杨明会郭建刚中国人民解放军总医院北京100853 兰州军区兰州总医院兰州730050

目的:分析不同海拔高度军人气道高反应性咳嗽中医证候、证型特点。方法:分析观察90例海拔400、1 500、4 500m高度部队官兵气道高反应性咳嗽症状特点,自拟中医四诊证候调查表,对符合纳入标准的病例进行临床症状问卷调查,完成调查,采集数... 详细信息

目的:分析不同海拔高度军人气道高反应性咳嗽中医证候、证型特点。方法:分析观察90例海拔400、1 500、4 500m高度部队官兵气道高反应性咳嗽症状特点,自拟中医四诊证候调查表,对符合纳入标准的病例进行临床症状问卷调查,完成调查,采集数据。结果:不同海拔高度军人气道高反应性咳嗽,临床症状有所不同,低海拔地区,常见症状有咳声频剧(30.00%),干咳、咳声短促(20.00%),咳嗽咽痒(20.00%),中等海拔地区常见症状有咳嗽咽痒(26.67%),咳声频剧(23.33%),高海拔地区常见症状有低热颧红(36.67%),无力气短(30.00%),咳嗽咽痒(30.00%),声音嘶哑(26.67%)。结论:不同海拔高度军人气道高反应性咳嗽特点:高海拔地区以风寒袭肺、肺气虚寒多见,低海拔和中等海拔地区以肺阴亏虚较为常见。

关键词：不同海拔高度气道高反应性咳嗽中医证候特点

≥65岁老年心力衰竭59例的临床特点及治疗

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第四军医大学学报 2007年第18期28卷 1699-1701页

作者：王梅安建平黄慧乔树洲任艳红刘丽华兰州军区兰州总医院干部病房甘肃兰州730050

目的:分析≥65岁老年心力衰竭的临床特点,为诊治老年人心力衰竭提供依据.方法:将心力衰竭患者112例按年龄分为≥65岁组和<65岁组,分别对其临床特点进行对比分析.结果:随着年龄的增加心力衰竭有其特点,≥65岁的老年患者多为冠心病(50.8%)... 详细信息

目的:分析≥65岁老年心力衰竭的临床特点,为诊治老年人心力衰竭提供依据.方法:将心力衰竭患者112例按年龄分为≥65岁组和<65岁组,分别对其临床特点进行对比分析.结果:随着年龄的增加心力衰竭有其特点,≥65岁的老年患者多为冠心病(50.8%),其次为肺心病(20.3%);临床症状不典型,程度以心功能III和Ⅳ级为多,高龄死亡率较高(87.5%).结论:≥65心力衰竭患者主要病因为冠心病,年龄越大,临床症状越不典型,心力衰竭程度越重,预后不良;治疗上要区别对待.

关键词：心力衰竭,充血性老年人临床特点

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方证对应的思考与展望

中医药信息 2014年第1期31卷 6-7页

作者：乔树洲张印张俊修徐睿鑫解放军医学院北京100853 兰州军区兰州总医院甘肃兰州730050

方药是中医治疗疾病的宝库,正确合理的运用方药是中医治疗疾病的基础,依据辨证论治的思路,辨清疾病的症候,然后对证下药,才能药到病除。随着现代医学的发展,中医对疾病的认识与治疗也在不断进步,通过方证对应的方法,可以对诊断明确的疾... 详细信息

方药是中医治疗疾病的宝库,正确合理的运用方药是中医治疗疾病的基础,依据辨证论治的思路,辨清疾病的症候,然后对证下药,才能药到病除。随着现代医学的发展,中医对疾病的认识与治疗也在不断进步,通过方证对应的方法,可以对诊断明确的疾病采取对应的治疗方法,对于提高中医药疗效有一定指导作用。

关键词：方证对应思考展望

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利用苛化沉淀合成铝酸钡实验研究

山东化工 2004年第6期33卷 6-8页

作者：吴瑞巧焦淑红邹若飞中铝山西分公司山西河津043300

通过实验研究 ,探讨了苛化沉淀与Al(OH) 3合成铝酸钡的工艺条件选择及铝酸钡的苛化效果。展望了以天然碳酸钡矿为原料加工钡盐添加剂在氧化铝工业中良好的应用前景。

关键词：苛化沉淀铝酸钡合成

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儿童心血管介入术的特殊并发症

临床军医杂志 2011年第3期39卷 532-533页

作者：鲁轩浩王梅张明旭乔淑洲解放军第1医院甘肃兰州730000 解放军兰州军区兰州总医院甘肃兰州730050

目的深入了解儿童在心脏介入术中出现的特殊类型并发症。方法收集2004—2009年346例实行心脏介入治疗患儿的病例资料,总结分析。结果手术不成功率为2%;非介入相关的其他血管出血者2例(0.5%);出现神经系统症状者46例(13%);血液系统异常者... 详细信息

目的深入了解儿童在心脏介入术中出现的特殊类型并发症。方法收集2004—2009年346例实行心脏介入治疗患儿的病例资料,总结分析。结果手术不成功率为2%;非介入相关的其他血管出血者2例(0.5%);出现神经系统症状者46例(13%);血液系统异常者2例(0.5%);不明原因腹痛者27例(7.8%);尿储留者16例(4.6%)。结论术中应对患儿的头部及相关部位进行射线防护,避免X线的长时间照射;重视患儿的术后临床症状。

关键词：儿童心血管介入并发症