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Amplification effect of intra-seasonal variability of soil moisture on heat extremes over Eurasia

Advances in Climate Change Research 2024年第1期15卷 1-8页

作者： Yi-Nuo WANG Zhi-Yan ZUO Liang qiao Kai-Wen ZHANG Mei-Yu CHANG Dong XIAO zou-Xing LIN Huan WANG Department of Atmospheric and Oceanic Sciences Institute of Atmospheric SciencesFudan UniversityShanghai 200438China CMA-FDU Joint Laboratory of Marine Meteorology Shanghai 200438China Key Laboratory of Cites Mitigation and Adaptation to Climate Change in Shanghai China Meteorological AdministrationShanghai 200030China Collaborative Innovation Centeron Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjing 211800China Shanghai Frontiers Science Center of Atmosphere-Ocean Interaction Shanghai 200123China College of Geography and Resources Science Sichuan Normal UniversityChengdu 610101China National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary Shanghai 202183China Chinese Academy of Meteorological Sciences China Meteorological AdministrationBeijing 100081China

Drying soil has been conducive to a high frequency of extreme high-temperature events over many regions worldwide in recent ***,changes in the intraseasonal variability of soil moisture can also influence the likelihood of extremely high *** previous investigators have examined the association between extremely high temperatures and large-scale atmospheric circulation variability,the role of land-atmosphere coupling dominated by soil moisture variability in extremely high temperatures,particularly over the Eurasian continent,is not well *** this study,on the basis of the Land Surface,Snow,and Soil Moisture Model Intercomparison Project,we found that land-atmosphere feedback amplified the variability of soil moisture in most regions of Eurasia during summer from 1980 to *** amplification of soil moisture variability is closely correlated with more intensive intraseasonal variability of surface air temperature and more frequent occurrences of extreme high-temperature events,particularly in Europe,Siberia,Northeast Asia,and the Indochina *** correlation implies that increasing the intraseasonal variability of soil moisture results in a high likelihood of heat extremes during summer in most parts of Eurasia except Asian desert *** the intraseasonal timescale,the land-atmosphere coupling increases the variability of surface sensible heat flux and net long-wave radiation heating the atmosphere by intensifying the soil moisture variability,thus amplifying the variability of surface air temperature and enhancing the extreme high-temperature *** finding demonstrates the importance of changes in intraseasonal soil moisture variability for the increasing likelihood of heat extremes in summer.

关键词： Soil moisture Intraseasonal variability Land-atmosphere coupling Heat extremes

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Effect of sintering temperature on luminescence properties of borosilicate matrix blue–green emitting color conversion glass ceramics

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Chinese Physics B 2019年第10期28卷 550-555页

作者： qiao-Yu Zheng Yang Li Wen-Juan Wu Ming-Ming Shi Bo-Bo Yang Jun zou School of Science Shanghai Institute of TechnologyShanghai 201418China School of Material Science and Engineering Shanghai Institute of TechnologyShanghai 201418China Institute of Beyond Lighting Academy for Engineering and TechnologyFudan UniversityShanghai 200433China Institute of New Materials&Industrial Technology Wenzhou UniversityWenzhou 325024China

The color conversion glass ceramics which were made of borosilicate matrix co-doped(SrBaSm)Si2O2N2:(Eu^3+Ce^3+) blue-green phosphors were prepared by two-step method in co-sintering. The change in luminescence properties and the drift of chromaticity coordinates(CIE) of the(SrBaSm)Si2O2N2:(Eu^3+Ce^3+) blue-green phosphors and the color conversion glass ceramics were studied in the sintering temperature range from 600℃ to 800℃. The luminous intensity and internal quantum yield(QY) of the blue-green phosphors and glass ceramics decreased with the sintering temperature increasing. When the sintering temperature increased beyond 750℃, the phosphors and the color conversion glass ceramics almost had no peak in photoluminescence(PL) and excitation(PLE) spectra. The results showed that the blue-green phosphors had poor thermal stability at higher temperature. The lattice structure of the phosphors was destroyed by the glass matrix and the Ce^3+ in the phosphors was oxidized to Ce^4+, which further caused a decrease in luminescent properties of the color conversion glass ceramics.

关键词： (SrBaSm)Si2O2N2:(Eu^3+Ce^3+) phosphors blue-green color conversion glass ceramic luminescent intensity thermal quenching effects sintering temperature

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Bimetallic site substitution of NiCoP nanoneedles as bifunctional electrocatalyst for boosted water splitting

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Nano Research 2024年第11期17卷 9540-9549页

作者： Ya Gao Yuhui qiao Xuanrong Li Chengyu Huang Jing Zhang Yirong Wang Xingli zou Zhonghong Xia Xinxin Yang Xionggang Lu Yufeng Zhao College of Sciences and Institute for Sustainable Energy Shanghai University Shanghai 200444 China School of Materials Science and Engineering Shanghai University Shanghai 200444 China State Key Laboratory of Advanced Special Steel and Shanghai Key Laboratory of Advanced Ferrometallurgy Shanghai University Shanghai 200444 China

The bimetallic nickel-cobalt phosphide (NiCoP) has been confirmed as an efficient electrocatalyst in water splitting. But little attention is paid to the selectivity and affinity of metal sites on hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). Herein, we report a trace-Zn-doping (2.18 wt.%) NiCoP (Zn-NiCoP) whereby the nanoparticles self-aggregated to form elongated nanoneedles. We discover that both Co and Ni sites can be replaced by Zn. The Co substitution improves HER, while the Ni substitution dramatically reduces the energy barrier of the rate-determining step (*O → *OOH). The negative shift of d-band centers after Zn doping ameliorates the intermediate desorption. Therefore, Zn-NiCoP demonstrates superior electrocatalytic activity with overpotentials of 48 and 240 mV for HER and OER at 10 and 50 mA·cm^(−2), respectively. The cell voltage with Zn-NiCoP as both anode and cathode in water splitting was as low as 1.35 V at 10 mA·cm^(−2).

关键词： Zn doping bimetallic phosphides bifunctional electrocatalyst overall water splitting

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Percutaneous microwave ablation and transcatheter arterial chemoembolization for serum tumor markers and prognostics of middle-late primary hepatic carcinoma

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World Journal of Gastrointestinal Surgery 2023年第12期15卷 2783-2791页

作者： Zhi-Peng Lin Da-Bei Huang Xu-Gong zou Yuan Chen Xiao-qun Li Jian Zhang Department of Interventional Medicine Zhongshan People’s HospitalZhongshan 528400Guangdong ProvinceChina

BACKGROUND Primary hepatic carcinoma(PHC)has an insidious onset and is usually diagnosed in the middle and late *** transcatheter arterial chemoembolization(TACE)is the preferred option for treating middle-and advanced-stage PHC,it has limited efficacy in killing tumor cells and poor long-term *** plus percutaneous microwave coagulation therapy(PMCT)is more effective than interventional therapy alone and can improve survival ***,there are few reports on the effects of TACE and PMCT on serum marker levels and the prognosis of patients with advanced *** To investigate the effect of PMCT+TACE on serum tumor markers and the prognosis of middle-late *** This retrospective study included 150 patients with middle-late PHC admitted to Zhongshan People’s Hospital between March 2018 and February *** were divided into a single group(treated with TACE,n=75)and a combined group(treated with TACE+PMCT,n=75).Before and after treatment,the clinical efficacy and serum tumor marker levels[carbohydrate antigen 19-9(CA19-9),alpha-fetoprotein(AFP),and carcinoembryonic antigen(CEA)]of both groups were *** 1-year survival rates and prognostic factors of the two groups were *** The combined group had 21 and 35 cases of complete remission(CR)and partial remission(PR),*** single group had 13 and 25 cases of CR and PR,decreased,with the decrease in the combined group being more significant(P<0.05).The 1-year survival rate of the combined group(80.00%)was higher than that of the single group(60.00%)(P<0.05).The average survival time within 1 year in the combined group was 299.38±61.13 d,longer than that in the single group(214.41±72.97 d,P<0.05).COX analysis revealed that tumor diameter,tumor number,and the treatment method were prognostic factors for patients with middle-late PHC(P<0.05).CONCLUSION TACE+PMCT is effective in treating patients with mid-late *** reduces the levels of tumor markers,prolongs

关键词： Middle-late primary hepatic carcinoma Percutaneous microwave coagulation therapy Transcatheter arterial chemoembolization Effect Tumor markers Prognosis Survival

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Tim-3 promotes cell aggressiveness and paclitaxel resistance through NF-κB/STAT3 signalling pathway in breast cancer cells

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Chinese Journal of Cancer Research 2020年第5期32卷 564-579页

作者： Yizi Cong Yuxin Cui Shiguang Zhu Jianqiao Cao Haidong zou Tracey AMartin Guangdong qiao Wenguo Jiang Zhigang Yu Department of Breast Surgery The Second HospitalCheeloo College of MedicineShandong UniversityJinan 250033China Department of Breast Surgery The Affiliated Yantai Yuhuangding Hospital of Qingdao UniversityYantai 264001China Cardiff China Medical Research Collaborative School of MedicineCardiff UniversityCardiffCF144XNUK

Objective:Although T-cell immunoglobulin and mucin-domain containing molecule-3(Tim-3)has been recognized as a promising target for cancer immunotherapy,its exact role in breast cancer has not been fully ***:Tim-3 gene expression in breast cancer and its prognostic significance were *** mechanisms were then explored in vitro by establishing Tim-3-overexpressing breast cancer ***:In a pooled analysis of The Cancer Genome Atlas(TCGA)database,Tim-3 gene expression levels were significantly higher(P<0.001)in breast cancer tissue,compared with normal ***-3 was a prognosis indicator in breast cancer patients[relapse-free survival(RFS),P=0.004;overall survival(OS),P=0.099].Tim-3 overexpression in Tim-3 low breast cancer cells promoted aggressiveness of breast cancer cells,as evidenced by enhanced proliferation,migration,invasion,tight junction deterioration and tumor-associated tubal ***-3 also enhanced cellular resistance to ***,Tim-3 exerted its function by activating the NF-κB/STAT3 signalling pathway and by regulating gene expression[cyclin D1(CCND1),C-Myc,matrix metalloproteinase-1(MMP1),TWIST,vascular endothelial growth factor(VEGF)upregulation,concomitant with Ecadherin downregulation).Lastly,Tim-3 downregulated tight junction-associated molecules zona occludens(ZO)-2,ZO-1 and occludin,which may further facilitate tumor ***:Tim-3 plays an oncogenic role in breast cancer and may represent a potential target for antitumor therapy.

关键词： Breast neoplasm hepatitis A virus cellular receptor 2 tight junction aggression chemoresistance

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Potent anti-angiogenesis and anti-tumor activity of a nove human anti-VEGF antibody, MIL60

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Cellular & Molecular Immunology 2014年第3期11卷 285-293页

作者： Jing Yang qun Wang Chunxia qiao Zhou Lin Xinying Li Yifei Huang Tingting Zhou Yan Li Beifen Shen Ming Lv Jiannan Feng Laboratory of Immunology Institute of Basic Medical Sciences Beijing China Department of Pathogens and Immunology Logistics College of Chinese People's Armed Police Forces Tianjin China Department of Ophthalmology General Hospital of People's Liberation Army Beijing China These authors contributed equally to this work

Angiogenesis is crucial for tumor development, growth and metastasis. Vascular endothelial growth factor （VEGF） has been implicated in promoting solid tumor growth and metastasis via stimulating tumor-associated angiogenesis, and blocking the activity of VEGF can starve tumors. Avastin, which is a humanized anti-VEGF antibody, has been successfully applied in clinics since 2004. However, the price of Avastin is extremely high for Chinese people. Here, we report a novel human anti-VEGF neutralizing antibody, MIL60, which shows an affinity comparable to that of Avastin （the KD value of MIL60 was 44.5 pM, while that of Avastin was 42.7 pM）. MIL60 displays favorable actions in inhibiting VEGF-triggered endothelial cell proliferation （the IC5o value of M IL60 was 31-6.4 ng/ml and that of Avastin was 47--.8.1 ng/ml）, migration （8 pg/ml or 0.8 pg/ml MIL60 versusthe control： P〈O.05） and tube formation （2 I^g/ml or 0.2 lzg/ml MIL60 versusthe control： P〈O.05） viathe VEGFR2 signaling pathway. Moreover, MIL60 was shown to inhibit tumor growth and angiogenesis in vivo in xenograft models of human colon carcinoma and ovarian cancer using immunotherapy and immunohistochemistry analysis （MIL60 versus N.S.： P=0.0007; Avastin versus N.S.： P=0.00046）. These data suggest that MIL60 is a potential therapeutic, anti-angiogenic agent. Our work provides a novel anti-VEGF antibody, which can be considered an anti-tumor antibody candidate and a new option for patients with various cancers.

关键词： angiogenesis anti-VEGF antibody cancer

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The Impact of Relative Humidity and Atmospheric Pressure on Mortality in Guangzhou, China

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Biomedical and Environmental Sciences 2014年第12期27卷 917-925页

作者： OU Chun Quan YANG Jun OU qiao qun LIU Hua Zhang LIN Guo Zhen CHEN Ping Yan QIAN Jun GUO Yu Ming State Key Laboratory of Organ Failure Research Department of Biostatistics School of Public Health and Tropical Medicine Southern Medical University National Institute for Communicable Disease Control and Prevention Chinese Center for Disease Control and Prevention Guangzhou First People's Hospital Guangzhou Medical University Guangzhou Center for Disease Control and Prevention Department of Mathematics and Physics School of Biomedical Engineering Southern Medical University Department of Epidemiology and Biostatistics School of Population Health The University of Queensland

Objective Although many studies have examined the effects of ambient temperatures on mortality, little evidence is on health impacts of atmospheric pressure and relative humidity. This study aimed to assess the impacts of atmospheric pressure and relative humidity on mortality in Guangzhou, China. Methods This study included 213,737 registered deaths during 2003-2011 in Guangzhou, China. A quasi-Poisson regression with a distributed lag non-linear model was used to assess the effects of atmospheric pressure/relative humidity. Results We found significant effect of low atmospheric pressure/relative humidity on mortality. There was a 1.79% （95% confidence interval： 0.38%-3.22%） increase in non-accidental mortality and a 2.27% （0.07%-4.51%） increase in cardiovascular mortality comparing the 5th and 25th percentile of atmospheric pressure. A 3.97% （0.67%-7.39%） increase in cardiovascular mortality was also observed comparing the 5th and 25th percentile of relative humidity. Women were more vulnerable to decrease in atmospheric pressure and relative humidity than men. Age and education attainment were also potential effect modifiers. Furthermore, low atmospheric pressure and relative humidity increased temperature-related mortality. Conclusion Both low atmospheric pressure and relative humidity are important risk factors of mortality. Our findings would be helpful to develop health risk assessment and climate policy interventions that would better protect vulnerable subgroups of the population.

关键词： Relative humidity Atmospheric pressure Temperature Mortality

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Enhanced mechanical performance of gradient-structured CoCrFeMnNi high-entropy alloys induced by industrial shot-blasting

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Rare Metals 2023年第3期42卷 982-993页

作者： Ming-Zhi Zhang Kun Zhang Kai-Kai Song Xiao-Yu zou Wei-Dong Song Ke-Feng Li Li-Na Hu Ze-qun Zhang Jürgen Eckert Shenzhen Research Institute of Shandong University Shenzhen 518057China CAS Key Laboratory of Microgravity(National Microgravity Laboratory) Institute of MechanicsChinese Academy of SciencesBeijing100190China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China School of Mechanical Electrical and Information EngineeringShandong UniversityWeihai 264209China Guangdong Institute of Materials and Processing Guangdong Academy of SciencesGuangzhou 510650China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJinan 250061China Erich Schmid Institute of Materials Science Austrian Academy of SciencesLeoben 8700Austria Department of Materials Science Montanuniversitat LeobenLeoben 8700Austria

In this study,CoCrFeMnNi high-entropy alloys(HEAs)with a surface gradient nanostructure were produced using industrial shot blasting,which improved their mechanical properties compared to the untreated *** severely plastically deformed(SPD)surface layer had a multi-scale hierarchical structure with a high density of stacking faults,deformation nanotwins,and amorphous *** depth of the SPD layer steadily increased as the shot-blasting time *** differences in the microhardness and tensile strength before and after shotblasting demonstrated the significant effect of the SPD layer on the mechanical *** microhardness of the homogenized HEA was~5 *** comparison,the maximum microhardness of the specimens after 20 min of shot blasting was~8.0 GPa at the *** yield strength also improved by 178%,and a large ductility of~36%was *** nanograin boundary,stacking fault,and twin strengthening within the gradientnanostructured surface layer caused the strength to *** tensile deformation,strain concentration began at the surface of the specimen and gradually spread to the ***,the gradient-nanostructured surface layer with improved strain hardening can prevent early necking and ensure steady plastic deformation so that high toughness is achieved.

关键词： High-entropy alloy Shot blasting Gradient structure Mechanical property Deformation mechanism

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A precise velocity field of tectonic deformation in China as inferred from intensive GPS observations

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Science China Earth Sciences 2012年第5期55卷 695-698页

作者： LI Qiang YOU XinZhao YANG ShaoMin DU RuiLin qiao XueJun zou Rong WANG Qi National Infrastructure of Earthquake Centre Beijing 100036 China Institute of Seismology China Earthquake Administration Wuhan 430071 China＂ Planetary Science Institute China University of Geosciences Wuhan 430074 China

Active tectonics, e.g., faulting, folding, and rifting are clearly manifested over the vast territory of China. The in-tensive crustal deformation with long-lived structures has given rise to numerous highly-elevated mountains in the western China with the Yangtze and Yellow rivers downstreaming to the east,as well as resulting in catastrophicearthquakes with huge fatalities in the historical times. Quantifying crustal deformation into its amount, distribu- tion, and timing is prerequisite for an understanding of the nature of geological evolution, climate-tectonics interaction, and ultimately the geodynamic aspects that control these processes. Moreover, monitoring active deformation with great precision is of fundamental importance in trying to forecast earthquake or assess seismic hazard for an earth- quake-prone country like China.

关键词：中国西部构造变形场 GPS观测速度场地震危险性评估密集地球动力学活动构造

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Fecal microbiota reveal adaptation of herbivores to the extreme environment of the Qinghai–Tibet Plateau

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Grassland Research 2024年第2期3卷 155-170页

作者： Hao zou Qi Li Jie Liu Xiangtao Wang qun Gao Yunfeng Yang Xinquan Zhao State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems Center for Grassland MicrobiomeCollege of Pastoral Agriculture Science and TechnologyLanzhou UniversityLanzhouGansuChina Qiangtang Alpine Grassland Ecosystem Research Station&College of Animal Science Xizang Agricultural and Animal Husbandry UniversityLinzhiXizangChina Institute of Environment and Ecology Tsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhenGuangdongChina State Key Laboratory of Plateau Ecology and Agriculture Qinghai UniversityXiningQinghaiChina

Background:Gut microbiota is pivotal in regulating hosts'biological processes and maintaining homeostasis,but knowledge about its role in wild herbivores in extreme environments remains ***:Gut bacteria and fungi were sequenced in ruminant(Chiru and Yak)and nonruminant(Kiang)herbivores on the Qinghai–Tibet Plateau,and their community structure,co-occurrence networks,functions,and assembly mechanisms were investigated using multivariate ecological and statistical ***:Kiang had lower gut microbial diversity than Chiru and *** host-specific exclusivity was greater than that of *** addition to the evidence of glycan biosynthesis and carbohydrate metabolism,Chiru had a high Firmicutes/Bacteroidetes ratio and low animal pathogen abundance,suggesting better adaptation to the plateau's harsh ***,members of gut microbiota tended to co-occur rather than co-exclude in all *** network complexity and stability patterns were observed between bacterial and fungal ***,gut bacterial assembly was primarily controlled by stochastic dispersal limitation and drift,whereas fungal assembly was primarily controlled by deterministic homogeneous selection except in ***:On the Qinghai–Tibet Plateau,Chiru and Yak exhibit more diverse gut microbiota and more diverse metabolic functions than Kiang,and gut bacteria are more divergent than gut fungi in these herbivores.

关键词： community assembly composition and diversity gut microbiota Qinghai-Tibet Plateau ruminant and nonruminant herbivores

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