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Journal of Environmental Sciences 2024年第9期143卷 1-11页

作者： xing-xing qiao Yu-Hang Xu Xiang-Ji Liu Sai-Le Chen Zhou Zhong Ya-Feng Li Jian Lü Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002China State Key Laboratory of Photocatalysis on Energy and Environment Fuzhou UniversityFuzhou 350116China

Potential health risks related to environmental endocrine disruptors(EEDs)have aroused research hotspots at the forefront of water treatment technologies.Herein,nitrogen-doped titanium dioxide/schwertmannite nanocomposites(N-TiO_(2)/SCH)have been successfully developed as heterogeneous catalysts for the degradation of typical EEDs via photo-Fenton processes.Due to the sustainable Fe(Ⅲ)/Fe(Ⅱ)conversion induced by photoelectrons,as-prepared N-TiO_(2)/SCH nanocomposites exhibit much enhanced efficiency for the degradation of bisphenol A(BPA;ca.100% within 60 min under visible irradiation)in a wide pH range of 3.0-7.8,which is significantly higher than that of the pristine schwertmannite(ca.74.5%)or N-TiO_(2)(ca.10.8%).In this photo-Fenton system,the efficient degradation of BPA is mainly attributed to the oxidation by hydroxyl radical(·OH)and singlet oxygen(^(1)O_(2)).Moreover,the possible catalytic mechanisms and reaction pathway of BPA degradation are systematically investigated based on analytical and photoelectrochemical analyses.This work not only provides a feasible means for the development of novel heterogeneous photo-Fenton catalysts,but also lays a theoretical foundation for the potential application of mineral-based materials in wastewater treatment.

关键词： Titanium dioxide Schwertmannite Fenton reaction Environmental endocrine disruptors Photocatalysis

Characterization,reactivity,source apportionment,and potential source areas of ambient volatile organic compounds in a typical tropical city

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Journal of Environmental Sciences 2023年第1期123卷 417-429页

作者： Xiaocong Cao qiao xing Shanhu Hu Wenshuai Xu Rongfu Xie Aidan Xian Wenjing Xie Zhaohui Yang Xiaochen Wu Hainan Research Academy of Environmental Sciences Haikou 571126China National Pilot Zone for Ecological Conservation(Hainan)Research Center Haikou 571126China

Based on one-year observation,the concentration,sources,and potential source areas of volatile organic compounds(VOCs)were comprehensively analyzed to investigate the pollution characteristics of ambient VOCs in Haikou,China.The results showed that the annual average concentration of total VOCs(TVOCs)was 11.4 ppb V,and the composition was dominated by alkanes(8.2 ppb V,71.4%)and alkenes(1.3 ppb V,20.5%).The diurnal variation in the concentration of dominant VOC species showed a distinct bimodal distribution with peaks in the morning and evening.The greatest contribution to ozone formation potential(OFP)was made by alkenes(51.6%),followed by alkanes(27.2%).The concentrations of VOCs and nitrogen dioxide(NO_(2))in spring and summer were low,and it was difficult to generate high ozone(O_(3))concentrations through photochemical reactions.The significant increase in O_(3)concentrations in autumn and winter was mainly related to the transmission of pollutants from the northeast.Traffic sources(40.1%),industrial sources(19.4%),combustion sources(18.6%),solvent usage sources(15.5%)and plant sources(6.4%)were identified as major sources of VOCs through the positive matrix factorization(PMF)model.The southeastern coastal areas of China were identified as major potential source areas of VOCs through the potential source contribution function(PSCF)and concentration-weighted trajectory(CWT)models.Overall,the concentration of ambient VOCs in Haikou was strongly influenced by traffic sources and long-distance transport,and the control of VOCs emitted from vehicles should be strengthened to reduce the active species of ambient VOCs in Haikou,thereby reducing the generation of O_(3).

关键词： Volatile organic compounds(VOCs) Ozone Positive matrix factorization(PMF) model Backward trajectory Potential source area

Reliability and Numerical Analysis of a Robot Safety System

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Journal of Systems Science & Complexity 2019年第4期32卷 1072-1092页

作者： qiao xing MA Dan College of Automation Harbin Engineering UniversityHarbin 150001China School of Mathematical Science Daqing Normal UniversityDaqing 163712China

This paper discusses a model for a repairable robot safety system composed of a safety component and two redundant robots according to a semi-group approach.The development of the model is divided into three phases:(Ⅰ)The use of pure analysis to prove the uniqueness of a classical solution to the model;(Ⅱ)The verification of this uniqueness by providing a non-negative solution to the model;and(Ⅲ)the formulation of reliability indices for the model,along with numerical examples to explain the results.The existence,uniqueness,and exponential stability of the solution of the repairable robot safety system is studied using Volterra-type integral-differential-equation theory,and the spectral distribution of the ACP operator is discussed.Moreover,the authors propose a method to investigate the steady-state indicator of the robot safety system with the safety component working,and with or without the component revolving,to make use of the correspondence of the eigenvector to the eigenvalue zero.The authors show that the robot’s operation,with or without the safety component revolving and with fractional motion,is superior to that with the safety component working.The novelty of the approach lies in its examination of a unique solution to the system and its exponential stability based on C0-semi-group theory,the co-final relative theory,and the functional analysis method.

关键词： Numerical analysis reliability index robot safety system stability

IL-21 accelerates xenogeneic graft-versus-host disease correlated with increased B-cell proliferation

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Protein & Cell 2013年第11期4卷 863-871页

作者： Xiaoran Wu Yi Tan qiao xing Shengdian Wang Key Laboratory of Infection and Immunity Institute of BiophysicsChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China

Graft-versus-host disease(GVHD)is a prevalent and potential complication of hematopoietic stem cell trans-plantation.An animal model,xenogeneic GVHD(X-GVHD),that mimics accurately the clinical presentation of GVHD would provide a tool for investigating the mechanism involved in disease pathogenesis.Murine models indi-cated that inhibiting IL-21 signaling was a good therapy to reduce GVHD by impairing T cell functions.We sought to investigate the effect of exogenous human IL-21 on the process of X-GVHD.In this study,human IL-21 was expressed by hydrodynamic gene delivery in BALB/c-Rag2−/−IL-2Rγc−/−(BRG)immunodeficient mice which were intravenously transplanted human peripheral blood mononuclear cells(hPBMCs).We found that human IL-21 exacerbated X-GVHD and resulted in rapid fatality.As early as 6 days after hPBMCs transplanted to BRG mice,a marked expansion of human CD19+B cells,but not T cells,was observed in spleen of IL-21-treated ***-pared with control group,IL-21 induced robust immuno-globulin secretion,which was accompanied by increased accumulation of CD19+CD38high plasma cells in spleen.In addition,we demonstrated that B-cell depletion was able to ameliorate X-GVHD.These results are the fi rst to fi nd in vivo expansion and differentiation of human B cells in response to IL-21,and reveal a correlation between the expansion of B cells and the exacerbation of xenogeneic GVHD.Our fi ndings show evidence of the involvement of B cells in X-GVHD and may have implications in the treat-ment of the disease.

关键词： IL-21 B cell xenogeneic GVHD immunode-fi cient mice immunoglobulin

生物炭对四环素和铜复合污染土壤生菜生长及污染物累积的影响

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环境科学 2024年第5期45卷 3037-3046页

作者：郑晨格裴欢欢张亚珊李嘉欣刘奋武乔星星秦俊梅山西农业大学资源环境学院太谷030800

通过生菜盆栽试验,研究四环素(TC)和铜(Cu)复合污染胁迫下施用不同生物炭(苹果枝条、玉米秸秆和谷子秸秆生物炭及其改性生物炭)对生菜生长的影响.结果表明,与CK相比,添加生物炭处理的生菜株高、根长、株鲜重和根鲜重均显著增加(P<0.05)... 详细信息

通过生菜盆栽试验,研究四环素(TC)和铜(Cu)复合污染胁迫下施用不同生物炭(苹果枝条、玉米秸秆和谷子秸秆生物炭及其改性生物炭)对生菜生长的影响.结果表明,与CK相比,添加生物炭处理的生菜株高、根长、株鲜重和根鲜重均显著增加(P<0.05).添加不同生物炭可以在不同程度上提高生菜生理指标中硝态氮、叶绿素和可溶性蛋白含量,降低丙二醛、脯氨酸含量以及过氧化氢酶活性,在幼苗期和成熟期生物炭对生菜生理指标的影响趋势一致.与CK相比,添加生物炭后生菜地上部和地下部的TC和Cu含量均有不同程度的降低,生菜地上部TC和Cu分别降低了2.49%~92.32%和12.79%~36.47%,地下部TC和Cu分别降低了12.53%~55.64%和22.41%~42.29%.相关性分析表明,生菜硝态氮、叶绿素和可溶性蛋白含量与生菜TC含量呈显著负相关,丙二醛、脯氨酸含量以及过氧化氢酶活性与生菜TC含量呈显著正相关,生菜抗性基因与TC含量呈显著正相关(P<0.05).总体趋势上,改性生物炭对提高生菜生长及降低污染物累积的效果优于原生物炭,其中改性谷子秸秆生物炭的修复效果最佳.

关键词：生物炭四环素(TC) 铜(Cu) 四环素类抗生素抗性基因(TC ARGs) 生菜

Anti-TOSO antibody treatment promotes T cell activation-induced cell death(AICD) in vitro and in vivo

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Chinese Science Bulletin 2014年第13期59卷 1374-1385页

作者： Yi Tan Xue Han Xiaoran Wu qiao xing Lieping Chen Shengdian Wang Key Laboratory of Infection and Immunity Institute of Biophysics Chinese Academy of Sciences University of Chinese Academy of Sciences Department of Immunobiology Yale University School of Medicine

T cell activation-induced cell death(AICD),that involves the induction of Fas-mediated apoptosis,is very important for the maintenance of immune homeostasis.TOSO was firstly described as an inhibitor of Fasmediated apoptosis and overexpressed in chronic lymphocytic leukemia.Recently,TOSO was identified as IgM FcR.In this study,we produced anti-TOSO monoclonal antibody(mAb)that could block the binding of IgM to TOSO and found that T cell apoptosis is negatively correlated with TOSO expression during T cell activation.Treatment of activated T cells with anti-TOSO blocking mAb promoted T cell AICD in in vitro AICD model,and treatment of xenogeneic-GVHD mice with the antibody also increased the sensitivity of activated T cells to Fasinduced apoptosis,which was accompanied by reduction of c-FLIPL expression and up-regulation of AP-1 complex.In summary,our data indicate the anti-apoptotic effect of TOSO in T cell AICD and open up new therapeutic prospects for the treatment of hematologic malignancies and immune disorders.

关键词： T细胞活化单克隆抗体细胞死亡治疗诱导体外 Fas介导淋巴细胞白血病

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基于退款保证的线上零售商体验渠道策略研究

中国管理科学 2024年第2期32卷 178-187页

作者：刘茹彭健程永生邓正华乔星军事科学院系统工程研究院北京100166 深圳职业技术大学经济学院广东深圳518055 江西财经大学工商管理学院江西南昌330032 重庆第二师范学院经济与工商管理学院重庆400044

在由制造商和线上零售商组成的O2O供应链中,考虑消费者退货行为,构建了基于退款保证的供应链博弈模型,探究线上零售商选择体验渠道的动机及其影响。研究发现:当线上零售商选择体验渠道策略时,各企业均会改变各自的定价策略,其中制造商... 详细信息

在由制造商和线上零售商组成的O2O供应链中,考虑消费者退货行为,构建了基于退款保证的供应链博弈模型,探究线上零售商选择体验渠道的动机及其影响。研究发现:当线上零售商选择体验渠道策略时,各企业均会改变各自的定价策略,其中制造商会提高批发价格,线上零售商则根据其退货损失来调整零售价格,但体验渠道策略能提升二者的利润水平;随着体验渠道的引入,能够激励部分消费者放弃退货(即退货率降低),从而有利于提升消费者福利。然而,从利润最大化的视角,线上零售商可能不会有动机选择体验渠道策略,这取决于产品退货率以及产品退货对消费者造成的退货损失,但退款保证能增大线上零售商引入体验渠道的动机。

关键词：线上零售商体验渠道消费者退货退款保证

Unraveling waterlogging tolerance-related traits with QTL analysis in reciprocal intervarietal introgression lines using genotyping by sequencing in rapeseed(Brassica napus L.)

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Journal of Integrative Agriculture 2020年第8期19卷 1974-1983页

作者： DING Xiao-yu XU Jin-song HUANG He qiao xing SHEN Ming-zhen CHENG Yong ZHANG Xue-kun Key Laboratory of Oil Crop Biology and Genetic Improvement Ministry of Agriculture and Rural Affairs/Oil Crops Research InstituteChinese Academy of Agricultural SciencesWuhan 430070P.R.China

Soil waterlogging is a major environmental stress that suppresses the growth and productivity of rapeseed(Brassica napus L.).Natural genetic variations in waterlogging tolerance(WT)were observed but no QTL mapping has been done for WT related traits in rapeseed.In this study,QTL associated with three WT related traits including relative root length(RRL),relative hypocotyl length(RHL)and relative fresh weight(RFW)were dissected using a set of reciprocal introgression lines(ILs)derived from the cross GH01×ZS9,which showed significant difference in WT.Genotyping-by-sequencing(GBS)of the populations were performed,totally 1468 and 1450 binned SNPs were identified for GIL(GH01 as the recurrent parent)and ZIL(ZS9 as the recurrent parent)population,respectively.A total of 66 distinct QTLs for WT at the seedling establishment stage including 31 for RRL,17 for RHL and 18 for RFW were detected.Among the 66 QTLs,20(29.4%)QTLs were detected in both genetic backgrounds and then they were integrated into six QTL clusters,which can be targeted in rapeseed breeding for improvement of WT through marker-assisted selection(MAS).Based on the physical positions of SNPs and the functional annotation of the Arabidopsis thaliana genome,56 genes within the six QTL cluster regions were selected as preliminary candidate genes,then the resequencing and transcriptome information about parents were applied to narrow the extent of candidate genes.Twelve genes were determined as candidates for the six QTL clusters,some of them involved in RNA/protein degradation,most of them involved in oxidation-reduction process.These findings provided genetic resources,candidate genes to address the urgent demand of improving WT in rapeseed breeding.

关键词： Brassica napus candidate genes marker-assisted selection quantitative trait loci mapping waterlogging tolerance

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基于三维网格卷积的布料仿真模拟

计算机工程与设计 2024年第4期45卷 1264-1271页

作者：靳雁霞刘亚变杨晶史志儒张翎乔星宇中北大学计算机科学与技术大数据学院山西太原030051

针对当前布料仿真中模拟成本高且耗时长的问题,提出一种直接对三维布料网格卷积的布料模拟方法。对三维布料网格进行螺旋卷积,使用点填充方法增加采样点,存储局部域;采用顶点抽取算法对局部块进行池化,使用基于Gauss-Bonnet定理曲率的... 详细信息

针对当前布料仿真中模拟成本高且耗时长的问题,提出一种直接对三维布料网格卷积的布料模拟方法。对三维布料网格进行螺旋卷积,使用点填充方法增加采样点,存储局部域;采用顶点抽取算法对局部块进行池化,使用基于Gauss-Bonnet定理曲率的惩罚因子对顶点抽取算法进行增强,当局部块数量小于开始时数量的60%时停止顶点抽取;最后训练神经细分网络对抽取后的整体网格进行上采样,其中使用改进的蝶形细分算法生成新顶点。实验结果表明,与目前已有方法相比,该布料模拟方法能够保留丰富真实的褶皱,减少模拟成本和时间,是一种高效的布料模拟方法。

关键词：布料仿真螺旋卷积局部域惩罚因子顶点抽取神经细分网络蝶形细分算法

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鸭源马尿气球菌的鉴定及全基因组测序分析

中国预防兽医学报 2024年第2期46卷 128-139页

作者：张菡舒静超张晓静董青彭志锋边传周乔宏兴河南省动物肠道疫病防控国际联合实验室河南郑州450046 河南炎黄生物工程有限公司河南郑州453822 郑州安图生物工程股份有限公司河南郑州450016 河南牧业经济学院动物医药学院河南郑州450046

为鉴定一株鸭源分离菌,并探究其生物信息学特性,本研究分别通过Pacbio Sequel三代测序技术和Illumina NovaSeq二代测序技术对该株鸭源分离菌进行全基因组测序;基于该分离菌16S rRNA基因序列构建进化树;通过GTDB基于基因组之间的平均核... 详细信息

为鉴定一株鸭源分离菌,并探究其生物信息学特性,本研究分别通过Pacbio Sequel三代测序技术和Illumina NovaSeq二代测序技术对该株鸭源分离菌进行全基因组测序;基于该分离菌16S rRNA基因序列构建进化树;通过GTDB基于基因组之间的平均核苷酸相似性及采用infer软件构建120个单拷贝基因序列进化树并对其分类;利用NR数据库比对分离菌全基因组蛋白编码基因序列;采用VFDB数据库分析该分离菌相关毒力基因;采用K-B纸片法测定分离菌对21种药物的药敏性试验;采用CARD数据库分析分离菌的耐药基因;利用GO、KEGG、COG数据库对分离菌进行基因功能、信号通路及基因的注释。测序结果显示分离菌由一个环形染色体和一个环形质粒组成,大小分别为2 133 811 bp和37 505 bp,GC含量分别为39.04%和35.03%;通过GTDB分类及NR数据库比对分析显示,该菌为马尿气球菌亚种;VFDB数据库比对发现6种致病毒力基因;药敏试验结果显示分离菌对红霉素、多西环素、庆大霉素、卡那霉素等多种药物耐药,CARD数据库比对发现6种耐药基因;基因功能分析显示,1 277个基因参与25类代谢通路,1 767个基因编码蛋白质,3 304个基因与分子功能相关,1 977个基因与细胞组分相关,4 421个基因与生物学过程相关。本研究对鸭源分离菌进行全基因组测序及基因组结构、功能分析,丰富了鸭源马尿气球菌全基因组数据库资料,完善了该菌的系统进化信息,分析了其毒力因子和相关耐药基因,为后续对该菌株分子生物学特征、致病性和耐药基因筛选提供了基因组信息和基因资源。

关键词：马尿气球菌全基因组序列耐药性致病性