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上海市长宁区社区老年人家庭环境跌倒相关因素发生现况的调查

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公共卫生与预防医学 2024年第4期35卷 58-61页

作者：赵倩倩张磊佘艳高慧周方家余力姜玉夏庆华上海市长宁区疾病预防控制中心上海200051

目的了解长宁区社区老年人居家环境安全现况,识别老年人居家环境跌倒相关危险因素,以采取针对性的整改措施,为老年人创造更加安全的适老环境。方法采用分阶段随机抽样方法抽取长宁区十个街道201户老年人家庭,采用自行设计的《老年人... 详细信息

目的了解长宁区社区老年人居家环境安全现况,识别老年人居家环境跌倒相关危险因素,以采取针对性的整改措施,为老年人创造更加安全的适老环境。方法采用分阶段随机抽样方法抽取长宁区十个街道201户老年人家庭,采用自行设计的《老年人居家住宅环境跌倒相关安全性评估表》,由社区医生进行现场调查和评估收集信息,采用Epidata 3.1录入数据和SAS 9.2进行统计学分析。结果调查对象过去一年里跌倒发生率为19.90%,每个家庭的致跌环境危险因素得分/环境危险因素数在0至25之间,平均为9项次(标准差4.71)。多因素logistic回归分析结果显示,在排除了年龄、服药数量等因素的影响外,高致跌环境水平(居家环境致跌危险因素数量≥12个)仍是老年人跌倒的独立危险因素(OR=3.835,95%CI:1.718~8.561)。结论致跌环境危险因素普遍存在于社区老年人居家环境中,应通过重点改善居家环境,降低老年人跌倒发生风险,为老年人打造安全舒适的居家环境。

关键词：老年人跌倒居家环境危险因素

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超疏水棉织物制备及其雾收集性能

西安工程大学学报 2024年第3期38卷 1-7页

作者：王煦漫卢俊龙张彩宁柴柏龙赵倩倩马志豪黄静寰西安工程大学材料工程学院陕西西安710048

为解决水资源短缺问题,以六水合硝酸钴、尿素、氟化铵为原料,通过水热法在棉织物上生长出碱式碳酸钴纳米棒,经硬脂酸表面处理后制备超疏水棉织物。采用XRD、FT-IR及SEM对该棉织物进行表征,研究棉织物种类、收集距离和雾流量等对超疏水... 详细信息

为解决水资源短缺问题,以六水合硝酸钴、尿素、氟化铵为原料,通过水热法在棉织物上生长出碱式碳酸钴纳米棒,经硬脂酸表面处理后制备超疏水棉织物。采用XRD、FT-IR及SEM对该棉织物进行表征,研究棉织物种类、收集距离和雾流量等对超疏水棉织物雾收集性能的影响,同时考察了该织物的雾收集持久性和自清洁性能。实验结果显示,超疏水棉织物具有最佳的雾收集性能,可达1 006.85 mg/(cm^(2)·h);雾收集性能随收集距离减小和雾流量增大而增加,当收集距离和雾流量分别为3 cm和237 mL/h时,集雾效率高达1 514.65 mg/(cm^(2)·h)。此外,超疏水棉织物还具有良好的雾收集持久性和自清洁性能。

关键词：超疏水棉织物雾收集雾流量碱式碳酸钴

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Abiotic stress treatment reveals expansin like A gene OfEXLA1 improving salt and drought tolerance of Osmanthus fragrans by responding to abscisic acid

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Horticultural Plant Journal 2024年第2期10卷 573-585页

作者： Bin Dong qianqian Wang Dan Zhou Yiguang Wang Yunfeng Miao Shiwei Zhong Qiu Fang Liyuan Yang Zhen Xiao Hongbo zhao School of Landscape Architecture Zhejiang Agriculture and Forestry UniversityHangzhouZhejiang 311300China Zhejiang Provincial Key Laboratory of Germplasm Innovation and Utilization for Garden Plants HangzhouZhejiang 311300China Key Laboratory of National Forestry and Grassland Administration on Germplasm Innovation and Utilization for Southern Garden Plants HangzhouZhejiang 311300China

Sweet osmanthus(Osmanthus fragrans) is a having general approval aromatic tree in China that is widely applied to landscaping and gardening. However, the evergreen tree adaptability is limited by many environmental stresses. Currently, limited information is available regarding the genetic analysis and functional identification of expansin genes in response to abiotic stress in sweet osmanthus. In this study, a total of 29 expansin genes were identified and divided into four groups by genome-wide analysis from the sweet osmanthus genome. Transcriptome and quantitative Real-time PCR analysis showed that the cell wall-localized protein expansin-like A(OfEXLA1) gene was significantly induced by salt and drought treatment. Histochemical GUS staining of transgenic Arabidopsis lines in which GUS activity was driven with the OfEXLA1 promoter, GUS activity was significantly induced by salt, drought, and exogenous abscisic acid(ABA). In yeast, we found OfEXLA1overexpression significantly improved the population of cells compared with wild-type strains after NaCl and polyethylene glycol(PEG)treatment. Additionally, OfEXLA1 overexpression not only promoted plant growth, but also improved the salt and drought tolerance in Arabidopsis. To gain insight into the role of ABA signaling in the regulation of OfEXLA1 improving abiotic tolerance in sweet osmanthus, four differentially expressed ABA Insensitive 5(ABI5)-like genes(OfABL4, OfABL5, OfABL7, and OfABL8) were identified from transcriptome, and dualluciferase(dual-LUC) and yeast one hybrid(Y1H) assay showed that OfABL4 and OfABL5 might bind to OfEXLA1 promoter to accumulate the OfEXLA1 expression by responding to ABA signaling to improve abiotic tolerance in sweet osmanthus. These results provide the information for understanding the molecular functions of expansin-like A gene and molecular breeding of sweet osmanthus in future.

关键词： Osmanthus fragrans Abiotic tolerance Expansin Abscisic acid

Twisted Phosphors that Violate Kasha's Exciton Model in Organic Systems

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Chinese Journal of Chemistry 2024年第11期42卷 1237-1246页

作者： Boyi Fu Guangming Wang Jiuyang Li Junbo Li Xun Li Xiaoya zhao Shuhui Ding Guoping Yan qianqian Yan Kaka Zhang School of Materials Science and Engineering Wuhan Institute of TechnologyWuhanHubei430205 China Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules Shanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesChinese Academy of Sciences345 Lingling RoadShanghai200032 China

Kasha's exciton model proposes that T1 energy levels of organic compounds are insensitive to molecular aggregation and microenvironment change because of negligible small transition dipole moments of T1 *** model holds true in most organic systems till *** we report the fabrication of twisted organic phosphors with intramolecular charge transfer characters and flexible molecular *** doped into different organic matrices,the twisted phosphor adopts different conformation,exhibits distinct phosphorescence colors and T1 energy levels,which violates Kasha's exciton model in organic *** that the change of phosphorescence colors and maxima can be readily distinguished by human eyes and conventional instrument,the twisted phosphors would be exploited as a new type of molecular probe,which would exhibit potential application in optical sensing and stimuli-responsive systems.

关键词： Afterglow Twisted phosphor Triplet excited state Room-temperature phosphorescence Luminescence Spin-orbit coupling

Enhancing crystal integrity and structural rigidity of CsPbBr_(3) nanoplatelets to achieve a narrow colorsaturated blue emission

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Light(Science & Applications) 2024年第5期13卷 985-997页

作者： qianqian Huang Wenxu Yin Bo Gao Qingsen Zeng Dong Yao Hao Zhang Yinghe zhao Weijia Zheng Jiaqi Zhang Xuyong Yang Xiaoyu Zhang Andrey L.Rogach Key Laboratory of Automobile Materials MOE School of Materials Science&Engineeringand Jilin Provincial International Cooperation Key Laboratory of High-Efficiency Clean Energy MaterialsJilin UniversityChangchunChina. State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchunChina. State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhanHubeiChina. Department of Chemistry University of VictoriaVictoriaBCCanada. Key Laboratory of Advanced Display and System Applications of Ministry of Education Shanghai UniversityShanghaiChina. Department of Materials Science and Engineering and Centre for Functional Photonics(CFP)City University of Hong KongHong Kong S.A.RChina

Quantum-confined CsPbBr_(3) perovskites are promising blue emitters for ultra-high-definition displays,but their soft lattice caused by highly ionic nature has a limited ***,we endow CsPbBr_(3) nanoplatelets(NPLs)with atomic crystal-like structural rigidity through proper surface engineering,by using strongly bound N-dodecylbenzene sulfonic acid(DBSA).A stable,rigid crystal structure,as well as uniform,orderly-arranged surface of these NPLs is achieved by optimizing intermediate reaction stage,by switching from molecular clusters to mono-octahedra,while interaction with DBSA resulted in formation of a Cs_(x)O monolayer shell capping the NPL *** a result,both structural and optical stability of the CsPbBr3 NPLs is enhanced by strong covalent bonding of DBSA,which inhibits undesired phase transitions and decomposition of the perovskite phase potentially caused by ligand ***,rather small amount of DBSA ligands at the NPL surface results in a short inter-NPL spacing in their closely-packed films,which facilitates efficient charge injection and *** photoluminescence of the produced CsPbBr_(3) NPLs is bright(nearly unity emission quantum yield)and peaks at 457 nm with an extremely narrow bandwidth of 3.7 nm at 80 K,while the bandwidth of the electroluminescence(peaked at 460 nm)also reaches a record-narrow value of 15 nm at room *** value corresponds to the CIE coordinates of(0.141,0.062),which meets Rec.2020 standards for ultra-high-definition displays.

关键词： temperature stability narrow

Natural variation in the cytochrome c oxidase subunit 5B OsCOX5B regulates seed vigor by altering energy production in rice

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Journal of Integrative Agriculture 2024年第9期23卷 2898-2910页

作者： Chengwei Huang Zhijuan Ji qianqian Huang Liling Peng Wenwen Li Dandan Wang Zepeng Wu Jia zhao Yongqi He Zhoufei Wang Laboratory of Seed Science and Technology/Guangdong Key Laboratory of Plant Molecular Breeding/State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources/South China Agricultural University Guangzhou 510642China National Nanfan Research Institute(Sanya) Chinese Academy of Agricultural SciencesSanya 572025 China National Rice Research Institute Hangzhou 310006China

Seed vigor is a crucial trait for the direct seeding of *** we examined the genetic regulation of seed vigor traits in rice,including germination index(GI)and germination potential(GP),using a genome-wide association study *** major quantitative trait locus,qGI6/qGP6,was identified simultaneously for both GI and *** candidate gene encoding the cytochrome c oxidase subunit 5B(OsCOX5B)was validated for qGI6/*** disruption of OsCOX5B caused the vigor traits to be significantly lower in Oscox5b mutants than in the japonica Nipponbare wild type(WT).Gene co-expression analysis revealed that OsCOX5B influences seed vigor mainly by modulating the tricarboxylic acid cycle *** glucose levels were significantly higher while the pyruvic acid and adenosine triphosphate levels were significantly lower in Oscox5b mutants than in WT during seed *** elite haplotype of OsCOX5B facilitates seed vigor by increasing its expression during seed ***,we propose that OsCOX5B is a potential target for the breeding of rice varieties with enhanced seed vigor for direct seeding.

关键词： cytochrome c oxidase natural variation rice seed vigor

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北京某三甲医院精细化管理方法与实践

中国医院 2022年第6期26卷 88-90页

作者：赵前前首都医科大学附属北京朝阳医院北京市100020

目的:通过医院精细化管理平台建设,为医院医疗管理及经济经营管理提供及时、准确的数据抓手,提升医院的决策水平和管理效率。方法:利用大数据、ETL等技术将医院各信息系统中的数据进行采集、清洗、整合、存储;应用专家法和层次分析法等... 详细信息

目的:通过医院精细化管理平台建设,为医院医疗管理及经济经营管理提供及时、准确的数据抓手,提升医院的决策水平和管理效率。方法:利用大数据、ETL等技术将医院各信息系统中的数据进行采集、清洗、整合、存储;应用专家法和层次分析法等建立各管理主题的指标体系。结果:搭建了医院精细化管理平台;构建了医师临床业务能力评价体系和病种直接可控成本核算分析体系。结论:精细化管理平台可为提高医疗质量、科学评价医师临床业务能力与技术发展能力、实施有效的医疗成本控制等提供科学依据,辅助医院管理决策。先进信息技术的应用可为医院实现精细化管理和可持续发展提供抓手和保障。

关键词：公立医院精细化管理医师评价直接可控成本

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IL-13/IL-13RA2 signaling promotes colorectal cancer stem cell tumorigenesis by inducing ubiquitinated degradation of p53

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Genes & Diseases 2024年第1期11卷 495-508页

作者： Baoyu He Jing Liang qianqian Qin Yuqin Zhang Shuo Shi Jinghe Cao Zhixin Zhang Qingli Bie Rou zhao Li Wei Baogui Zhang Bin Zhang Department of Laboratory Medicine Affiliated Hospital of Jining Medical UniversityJining Medical UniversityJiningShandong 272000China Postdoctoral Mobile Station of Shandong University of Traditional Chinese Medicine JinanShandong 250355China Department of Reproductive Medicine Affiliated Hospital of Jining Medical UniversityJining Medical UniversityJiningShandong 272000China Department of Gastrointestinal Surgery Affiliated Hospital of Jining Medical UniversityJining Medical UniversityJiningShandong 272000China Institute of Forensic Medicine and Laboratory Medicine Jining Medical UniversityJiningShandong 272067China

Cancer stem cells(CSCs)are considered tumor-initiating cells and the main drivers of disease *** these rare cancer cells,however,remains challenging with respect to therapeutic ***,we report the up-regulation of IL-13RA2 expression in colorectal cancer(CRC)tissues and spheroid *** expression of IL-13RA2 was positively correlated with canonical stemness markers in *** further demonstrated that the level of IL-13 was up-regulated in the serum of CRC ***,recombinant IL-13(rIL13)stimulation promoted the sphere formation,proliferation,and migration of CRC cells in vitro and enhanced tumorigenesis in *** phenotype could be reversed by knocking down ***,IL-13 activated autophagy by inducing LC3I/LC3II transformation in CRC-CSCs,which was crucial for the biological functions of *** further demonstrated that IL-13RA2 acted as a modular link of the E3 ligase UBE3C and the substrate p53 protein,enhancing the interaction of UBE3C and p53,thereby inducing the K48-linked ubiquitination of *** conclusion,the IL-13/IL-13RA2 signaling cascade promotes CRC-CSC self-renewal and tumorigenesis by inducing p53 ubiquitination,adding an important layer to the connection between IL-13 and p53,which can be translated into novel targeted therapies.

关键词： Autophagy Colorectal cancer stem cells IL-13/IL-13RA2 signaling p53

Soybean(Glycine max)rhizosphere organic phosphorus recycling relies on acid phosphatase activity and specific phosphorusmineralizing-related bacteria in phosphate deficient acidic soils

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Journal of Integrative Agriculture 2024年第5期23卷 1685-1702页

作者： qianqian Chen Qian zhao Baoxing Xie Xing Lu Qi Guo Guoxuan Liu Ming Zhou Jihui Tian Weiguo Lu Kang Chen Jiang Tian Cuiyue Liang Root Biology Center State Key Laboratory for Conservation and Utilization of Subtropical Agro-BioresourcesCollege of Natural Resources and EnvironmentSouth China Agricultural UniversityGuangzhou 510642China College of Natural Resources and Environment South China Agricultural UniversityGuangzhou 510642China Henan Academy of Crops Molecular Breeding Henan Academy of Agricultural SciencesZhengzhou 450002China

Bacteria play critical roles in regulating soil phosphorus(P) cycling. The effects of interactions between crops and soil P-availability on bacterial communities and the feedback regulation of soil P cycling by the bacterial community modifications are poorly understood. Here, six soybean(Glycine max) genotypes with differences in P efficiency were cultivated in acidic soils with long-term sufficient or deficient P-fertilizer treatments. The acid phosphatase(AcP) activities, organic-P concentrations and associated bacterial community compositions were determined in bulk and rhizosphere soils. The results showed that both soybean plant P content and the soil AcP activity were negatively correlated with soil organic-P concentration in P-deficient acidic soils. Soil P-availability affected the ɑ-diversity of bacteria in both bulk and rhizosphere soils. However, soybean had a stronger effect on the bacterial community composition, as reflected by the similar biomarker bacteria in the rhizosphere soils in both P-treatments. The relative abundance of biomarker bacteria Proteobacteria was strongly correlated with soil organic-P concentration and AcP activity in low-P treatments. Further high-throughput sequencing of the phoC gene revealed an obvious shift in Proteobacteria groups between bulk soils and rhizosphere soils, which was emphasized by the higher relative abundances of Cupriavidus and Klebsiella, and lower relative abundance of Xanthomonas in rhizosphere soils. Among them, Cupriavidus was the dominant phoC bacterial genus, and it was negatively correlated with the soil organic-P concentration. These findings suggest that soybean growth relies on organic-P mineralization in P-deficient acidic soils, which might be partially achieved by recruiting specific phoCharboring bacteria, such as Cupriavidus.

关键词： organic phosphorus acid phosphatase soybean bacterial community phoC-harboring bacteria rhizosphere