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Observation of high ionic conductivity of polyelectrolyte microgels in salt-free solutions

Chinese Chemical Letters 2024年第4期35卷 255-259页

作者： qiangwei wang Huijiao Liu Mengjie wang Haojie Zhang Jianda Xie Xuanwei Hu Shiming Zhou Weitai Wu State Key Laboratory for Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy MaterialsThe Key Laboratory for Chemical Biology of Fujian Provinceand Department of ChemistryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China School of Materials Science and Engineering Xiamen University of TechnologyXiamen 361024China Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of ChinaHefei 230026China School of Chemistry and Chemical Engineering Ningxia UniversityYinchuan 750021China

Here, we report an observation that illustrate the potential of polyelectrolyte microgels in salt-free solutions to display a high ionic conductivity. Laser light scattering and ionic conductivity tests on very dilute aqueous dispersions of the microgels indicate that both small size and swollen state of gel particles play vital roles, which should favor the counterions to freely penetrate and leave gel particles, and thus can contribute to the ion-conducting property. Upon discovering this on microgels that are composed of imidazolium-based poly(ionic liquid), we also illustrate the generality of the finding to single lithium-ion polyelectrolyte microgels that are of more technically relevant features for applications, for instance, as injectable liquid “microgel-in-solution” electrolytes of high conductivity(ca. 8.2 × 10^(-2)S/m at 25.0 ℃ for1.0 × 10^(-2)g/m L of microgels in a LiNO_(3)-free 1:1 v/v mixture of 1,2-dioxolane and dimethoxymethane) and high lithium-ion transference number(0.87) for use in the rechargeable lithium-sulfur battery.

关键词： Polyelectrolhyte Stimuli-responsive Single-ion conducting Liquid electrolyte Lithium metal battery

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宫腔镜子宫肌瘤电切术对子宫肌瘤的疗效及对局部微循环、卵巢储备的影响分析

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黑龙江医学 2024年第1期48卷 18-20页

作者：王蔷薇张凤莲黄河科技学院附属医院妇产科河南郑州450000

目的:探讨宫腔镜子宫肌瘤电切术治疗子宫肌瘤的疗效。方法:回顾性分析2019年9月—2021年6月黄河科技学院附属医院妇产科收治的160例子宫肌瘤患者的临床资料,根据手术方案的不同将患者分为对照组(n=80)与研究组(n=80)。对照组采用腹腔镜... 详细信息

目的:探讨宫腔镜子宫肌瘤电切术治疗子宫肌瘤的疗效。方法:回顾性分析2019年9月—2021年6月黄河科技学院附属医院妇产科收治的160例子宫肌瘤患者的临床资料,根据手术方案的不同将患者分为对照组(n=80)与研究组(n=80)。对照组采用腹腔镜子宫肌瘤切除术;研究组采用宫腔镜子宫肌瘤电切术,对比两组的手术指标,治疗前与治疗后3 d的心率(HR)、促黄体生成素(LH)、血氧饱和度(SaO_(2))、促卵泡激素(FSH)、收缩压(SBP)、睾酮(T)水平。结果:两组手术时间差异无统计学意义(t=1.227,P>0.05),研究组患者术中失血量、卧床时间、住院时间小于对照组,差异有统计学意义(t=10.122、5.416、8.632,P<0.05);治疗后研究组患者LH、FSH、SaO_(2)、T水平高于对照组,差异有统计学意义(t=11.623、4.858、7.992、9.479,P<0.05),HR、SBP水平低于对照组,差异有统计学意义(t=10.864、11.093,P<0.05)。结论:宫腔镜子宫肌瘤电切术治疗子宫肌瘤的疗效良好确切,可有效保护子宫肌瘤患者卵巢储备功能,减轻手术对患者循环功能的影响。

关键词：子宫肌瘤腹腔镜宫腔镜子宫肌瘤电切术卵巢功能

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Gut microbiota dysbiosis involves in host non-alcoholic fatty liver disease upon pyrethroid pesticide exposure

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Environmental Science and Ecotechnology 2022年第3期11卷 83-92页

作者： Meng Li Tingting Liu Teng Yang Jiaping Zhu Yunqian Zhou Mengcen wang qiangwei wang Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects Institute of Pesticide and Environmental ToxicologyZhejiang UniversityHangzhou310058China Agricultural Technical Institute The Ohio State UniversityWoosterOH44691USA Global Education Program for AgriScience Frontiers Graduate School of AgricultureHokkaido UniversitySapporo060-8589Japan

A growing body of evidence has demonstrated the significance of the gut microbiota in host health,while the association between gut microbiota dysbiosis and multiple diseases is yet elusive in the scenario of exposure to widely used ***,we show that gut microbiota dysbiosis involves in host's abnormal lipid metabolism and consequently the non-alcoholic fatty liver disease in Xenopus laevis upon exposure to cis-bifenthrin,one of the most prevalent pyrethroid insecticides in the *** the guidance of gut microbiota analysis,we found that cis-bifenthrin exposure significantly perturbed the gut microbial community,and the specific taxa that served as biomarkers were *** profiling and association analysis further showed that a significant change of intestinal metabolites involved in lipid metabolic pathways were induced along with the microbiota dysbiosis upon exposure to *** investigation showed an altered functional regulation of lipids in the liver after cis-bifenthrin exposure and the accumulation of lipid droplets in ***,a change in deoxycholic acid alters bile acid hepatoenteral circulation,which affects lipid metabolism in the liver and ultimately causes the development of fatty liver ***,these findings provide novel insight into the gut microbiota dysbiosis upon pesticide exposure and their potential implication in the development of chronic host diseases related to liver metabolic syndrome.

关键词： Pyrethroid Xenopus laevis Metabolic disorders Dysbiosis gut microbiota

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生物质多孔碳复合相变材料制备和热性能研究

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化工新型材料 2024年第7期52卷 78-81页

作者：向德宁库慧益侯忠平林蔚王强伟吴学红湖北中烟工业有限责任公司武汉卷烟厂武汉430050 郑州轻工业大学能源与动力工程学院郑州450000

将木材通过高温碳化的方法制备三维生物质碳基材料用于相变材料载体,制备复合相变材料,并对复合相变材料进行结构表征、性能测试及防泄漏实验。结果表明:多孔碳载体材料导热孔道网络完整,保证了有机相变材料的高效稳定负载量;相比于纯... 详细信息

将木材通过高温碳化的方法制备三维生物质碳基材料用于相变材料载体,制备复合相变材料,并对复合相变材料进行结构表征、性能测试及防泄漏实验。结果表明:多孔碳载体材料导热孔道网络完整,保证了有机相变材料的高效稳定负载量;相比于纯相变材料,70%PA@GNS热导系数达到了0.763W/(m·K),提高了3.18倍;含有20%多孔碳复合材料的潜热值达到了182J/g,比理论值潜热值高了约7%;并能有效防止相变材料泄漏。

关键词：多孔碳复合相变材料导热系数潜热稳定性

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Characteristics of Mechanical Asphyxia:A Retrospective Epidemiological Study in Two Developed Cities in China

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Journal of Forensic Science and Medicine 2023年第1期9卷 57-63,I0001,I0002页

作者： Erwen Huang Guoli Lv Yumei wang qiangwei wang Jing Zhang Lie Liang Ben Liu Wen Yang Chuanyi Tang Chao Liu Jianding Cheng Guangdong Province Translational Forensic Medicine Engineering Technology Research Center Faculty of Forensic MedicineZhongshan School of MedicineSun Yat-Sen UniversityGuangzhouChina Guangzhou Forensic Science Institute GuangzhouChina The Institute of Criminal Science and Technology of Dongguan Public Security Bureau DongguanChina Guangzhou Public Security Bureau GuangzhouChina

Background:Mechanical asphyxia(MA)is *** epidemiological characteristics are shared and the others different among different MA *** and Objectives:To reveal the characteristics of different types of MA and provide reference data for forensic identification of *** and Methods:We analyzed 913 cases to reveal the epidemiological characteristics of MA in Dongguan and Guangzhou,***:Seven types of MA were identified and strangulation accounted for up to 89.2%.Those aged 20-29 were the most susceptible to all types,except for traumatic and positional *** accounted for 96.6%of hanging cases,and accident was the main manner of death in cases of choking,traumatic,and positional *** was the most common in cases of ligature strangulation(LS),manual strangulation(MS),smothering,and asphyxia concomitant with lethal mechanical *** homicide rate in LS was positively correlated with the rate of female victims(P<0.001,OR=21.14).In MS,the ratio of female:male was 101:15 in *** to native residents,migrant workers were more likely to suffer from LS and *** was used in 50.8%of hanging cases,while LS tools were evenly *** marks were mostly found above the thyroid cartilage in both hanging and LS *** U shaped marks were shown in 51.01%of hanging cases but absent in LS *** LS,ligature marks completely encircling the neck,discontinuous marks,as well as≥two marks,were more(P<0.001)than in *** LS and MS cases,abrasion and subcutaneous hemorrhages on the neck were more frequent than in hanging cases(P=0.004 and P<0.001),but the difference in frequency of blister marks was opposite(P<0.001).Conclusion:In summary,this study revealed the epidemiological characteristics of the MA cases in Guangzhou and Dongguan *** characteristics of death scene and autopsy findings are important in differentiation of different types of MA,especially between suicide and homicide.

关键词： Hanging ligature strangulation manual strangulation mechanical asphyxia smothering

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Intratumor heterogeneity,microenvironment,and mechanisms of drug resistance in glioma recurrence and evolution

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Frontiers of Medicine 2021年第4期15卷 551-561页

作者： Zhaoshi Bao Yongzhi wang qiangwei wang Shengyu Fang Xia Shan Jiguang wang Tao Jiang Beijing Neurosurgical Institute Capital Medical UniversityBeijing 100050China Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China Divison of Life Science Department of Chemical and Biological EngineeringCenter for Systems Biology and Human Healthand State Key Laboratory of Molecular NeuroscienceThe Hong Kong University of Science and TechnologyHong KongChina China National Clinical Research Center for Neurological Diseases Beijing 100050China Division of Life Science Hong Kong University of Science and TechnologyHong KongChina Center of Brain Tumor Beijing Institute for Brain DisordersBeijing 100069China Department of Radiotherapy Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China

Glioma is the most common lethal tumor of the human *** median survival of patients with primary World Health Organization grade IV glioma is only 14.6 *** World Health Organization classification of tumors of the central nervous system categorized gliomas into lower-grade gliomas and *** primary glioblastoma that usually develop de novo in the elderly,secondary glioblastoma enriched with an isocitrate dehydrogenase mutant typically progresses from lower-grade glioma within 5-10 years from the time of *** on various evolutional trajectories brought on by clonal and subclonal alterations,the evolution patterns of glioma vary according to different *** important features distinguish the normal brain from other tissues,e.g.,the composition of the microenvironment around the tumor cells,the presence of the blood-brain barrier,and *** underlying mechanism of glioma recurrence and evolution patterns of glioma are different from those of other types of *** studies correlated tumor recurrence with tumor heterogeneity and the immune ***,the detailed reasons for the progression and recurrence of glioma remain *** this review,we introduce the different mechanisms involved in glioma progression,including tumor heterogeneity,the tumor microenvironment and drug resistance,and their pre-clinical implements in clinical *** review aimed to provide new insights into further clinical strategies for the treatment of patients with recurrent and secondary glioma.

关键词： glioma evolution mechanism strategies tumor heterogeneity secondary glioma

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Reprogramming of phytopathogen transcriptome by a non-bactericidal pesticide residue alleviates its virulence in rice

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Fundamental Research 2022年第2期2卷 198-207页

作者： Haruna Matsumoto Yuan Qian Xiaoyan Fan Sunlu Chen Yanxia Nie Kun Qiao Dandan Xiang Xinzhong Zhang Meng Li Bo Guo Peilin Shen qiangwei wang Yunlong Yu Tomislav Cemava Mengcen wang State Key Laboratory of Rice Biology&Ministry of Agricultural and Rural Affairs Laboratory of Molecular Biology of Crop Pathogens and Insects Institute of Pesticide and Environmental ToxicologyZhejiang UniversityHangzhou 310058China Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province College of Agriculture and BiotechnologyZhejiang UniversityHangzhou 310058China Institute of Environmental Biotechnology Graz University of TechnologyPetersgasse 128010 GrazAustria Global Education Program for AgriScience Frontiers Graduate School of AgricultureHokkaido UniversitySapporo 0608589Japan State Key Laboratory of Crop Genetics and Germplasm Enhancement Nanjing Agricultural UniversityNanjing 210095China Ecology and Environmental Sciences Center South China Botanical GardenChinese Academy of SciencesGuangzhou 510650China Key laboratory of South Subtropical Fruit Biology and Genetic Resource Uilization(MOA) Instiute of Fruit Tree ResearchGuangdong Acadermy of Agricultural SciencesGuangzhou 510640China Tea Research Instiute Chinese Academy of Agriculural SciencesHangzhou 310008China Shanghai Intermnational Studies University Shanghai 200083China Xiaoshan Agricultural Comprehensive Development Zone&Management Committee Hangzhou 311200China

Bacteria equipped with virulence systems based on highly bioactive small molecules can circumvent their host's defense *** employing this strategy are currently threatening global rice *** the present study,variations in the virulence of the highly destructive Barkholderiaplantarii were observed in different rice-producing *** environment-linked variation was not attributable to any known host-related or external ***-occurrence analyses indicated a connection between reduced virulence and 5-Amino-l,3,4-thiadiazole-2-thiol(ATT),a non-bactericidal organic ***,which accumulates in rice plants during metabolization of specific agrochemicals,was found to reduce virulence factor secretion by *** up to 88.8%and inhibit pathogen virulence by hijacking an upstream signaling *** assessment of the newly discovered virulence inhibitor resulted in mechanistic insights into positive effects of ATT accumulation in plant *** of virulence alleviation were deciphered by integrating high-throughput data,gene knockout mutants,and molecular interaction ***,a histidine protein kinase in a two-component system that regulates virulence factor secretion,is likely the molecular target antagonized by *** findings provide novel insights into virulence modulation in an important plant-pathogen system that relies on the host's metabolic activity and subsequent signaling interference.

关键词： Phytopathogen Virulence factor Transcriptome reprogramming Agrochemical Pesticide Rice

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Chinese Glioma Genome Atlas(CGGA):A Comprehensive Resource with Functional Genomic Data from Chinese Glioma Patients

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Genomics, Proteomics & Bioinformatics 2021年第1期19卷 1-12页

作者： Zheng Zhao Ke-Nan Zhang qiangwei wang Guanzhang Li Fan Zeng Ying Zhang Fan Wu Ruichao Chai Zheng wang Chuanbao Zhang Wei Zhang Zhaoshi Bao Tao Jiang Beijing Neurosurgical Institute Capital Medical UniversityBeijing 100070China Department of Neurosurgery The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009China Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Center of Brain Tumor Beijing Institute for Brain DisordersBeijing 100069China China National Clinical Research Center for Neurological Diseases Beijing 100070China

Gliomas are the most common and malignant intracranial tumors in *** studies have revealed the significance of functional genomics for glioma pathophysiological studies and ***,access to comprehensive genomic data and analytical platforms is often ***,we developed the Chinese Glioma Genome Atlas(CGGA),a user-friendly data portal for the storage and interactive exploration of cross-omics data,including nearly 2000 primary and recurrent glioma samples from Chinese ***,open access is provided to whole-exome sequencing data(286 samples),mRNA sequencing(1018 samples)and microarray data(301 samples),DNA methylation microarray data(159 samples),and microRNA microarray data(198 samples),and to detailed clinical information(age,gender,chemoradiotherapy status,WHO grade,histological type,critical molecular pathological information,and survival data).In addition,we have developed several tools for users to analyze the mutation profiles,mRNA/microRNA expression,and DNA methylation profiles,and to perform survival and gene correlation analyses of specific glioma *** database removes the barriers for researchers,providing rapid and convenient access to high-quality functional genomic data resources for biological studies and clinical *** is available at http://***.

关键词： Glioma Functional genomics Chinese Glioma Genome Atlas Chinese cohort Database

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氧化石墨烯复合相变微胶囊制备及传热特性研究

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工程热物理学报 2023年第12期44卷 3414-3419页

作者：吴学红王凯王强伟陈亚南刘鹤王燕令常志娟桂阳海郑州轻工业大学能源与动力工程学院郑州450000

本文采用原位聚合法以氧化石墨烯物理改性密胺树脂为壳材,包覆石蜡制备石蜡@密胺树脂/氧化石墨烯相变微胶囊。石蜡@密胺树脂/氧化石墨烯复合相变微胶囊在保存了石蜡高储能密度的同时有效防止了石蜡泄漏,并且提高了其导热性。当质量分数... 详细信息

本文采用原位聚合法以氧化石墨烯物理改性密胺树脂为壳材,包覆石蜡制备石蜡@密胺树脂/氧化石墨烯相变微胶囊。石蜡@密胺树脂/氧化石墨烯复合相变微胶囊在保存了石蜡高储能密度的同时有效防止了石蜡泄漏,并且提高了其导热性。当质量分数ω为6%时,导热系数为1.25 W·m^(-1)·K^(-1),提高了7.8倍,潜热略有降低,潜热焓值为185.4 J·g^(-1),包覆率为70.4%。将制备的改性微胶囊进行防泄漏测试研究,展现出优异的热稳定性能。

关键词：相变微胶囊氧化石墨烯导热系数防泄漏

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“先知”:马克斯·韦伯的视角

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世界宗教文化 2021年第6期 105-111页

作者：王强伟山东大学犹太教与跨宗教研究中心山东大学儒学高等研究院

马克斯·韦伯将宗教"先知"视为其"克里斯玛"概念的典型代表,他对一般的宗教先知进行了系统研究。最为显著的是,韦伯在借鉴圣经学成果的基础上,以社会学方法创新性地集中研究了犹太教先知,在先知-预言的可理解性和易实践性、预言和律法... 详细信息

马克斯·韦伯将宗教"先知"视为其"克里斯玛"概念的典型代表,他对一般的宗教先知进行了系统研究。最为显著的是,韦伯在借鉴圣经学成果的基础上,以社会学方法创新性地集中研究了犹太教先知,在先知-预言的可理解性和易实践性、预言和律法之间的符合关系、预言的"理性化"升华趋向,以及先知行为本质的宗教性根源等方面提出了自己的洞见。他还采用比较宗教研究的方式进一步呈现了犹太教先知的独特性。通过对韦伯先知研究存在问题的反思,可以为我们的进一步研究提供启示和借鉴。

关键词：先知犹太教克里斯玛理性化比较研究

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