检索结果-南通市图书馆

Squeezing microwaves by magnetostriction

在线全文

学校读者我要写书评

暂无评论

National Science Review 2023年第5期10卷 208-214页

作者： Jie Li Yi-pu Wang Jian-qiang You Shi-Yao Zhu Interdisciplinary Center of Quantum Information Zhejiang Province Key Laboratory of Quantum Technology and Deviceand State Key Laboratory of Modern Optical InstrumentationSchool of PhysicsZhejiang University

Squeezed light finds many important applications in quantum information science and quantum metrology,and has been produced in a variety of physical systems involving optical non-linear processes.Here,we show how a non-linear magnetostrictive interaction in a ferrimagnet in cavity magnomechanics can be used to reduce quantum noise of the electromagnetic field.We show optimal parameter regimes where a substantial and stationary squeezing of the microwave output field can be achieved.Realization of the scheme is within reach of current technology in cavity electromagnonics and magnomechanics.Our work provides a new and practicable approach for producing s queezed vacuum states of electromagnetic fields,and may find promising applications in quantum information processing and quantum metrology.

关键词： squeezing of quantum noise cavity magnonics magnomechanics

Repair of the portal vein using a hepatic ligamentum teres patch for laparoscopic pancreatoduodenectomy: A case report

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第18期7卷 2879-2887页

作者： qiang Wei qiang-pu Chen Qing-Hai Guan Wen-Tao Zhu Department of Hepatobiliary Surgery and Clinical Nutrition Center Binzhou Medical University Hospital

BACKGROUND Laparoscopic pancreatoduodenectomy (LPD) has been developed gradually with the advances in surgical laparoscopic techniques. It is technically challenging to perform LPD with portal vein resection and reconstruction. CASE SUMMARY A 71-year-old female patient was diagnosed with distal cholangiocarcinoma. After preoperative examination and rigorous preoperative preparation, the patient underwent LPD using 3D laparoscopy on July 17, 2018. During the surgery, we found that the tumor invaded the right wall of the portal vein;thus, pancreaticoduodenectomy combined with partial portal vein wall resection was performed. The defect of the portal vein wall was approximately 2.5 cm × 1.0 cm. The hepatic ligamentum teres was excised by laparoscopy and then recanalized in vitro. Following recanalization, the hepatic ligamentum teres was cut longitudinally and then trimmed into vascular patches that were then used to reconstruct the defect of the portal vein through 3D laparoscopy. The operative time was 560 min, and intraoperative blood loss was 100 mL. The duration of the blood occlusion time was 63 min. No blood transfusion was required. The patient underwent enhanced recovery after surgery procedures after the operation. The patient was discharged on postoperative day 11. Follow-up for 6 months after discharge showed no stenosis of the portal vein and good patency of blood flow. CONCLUSION It is safe and feasible to use the hepatic ligamentum teres patch to repair portal vein in LPD. However, the long-term patency of this technique for venous reconstruction requires further investigation.

关键词： Hepatic ligamentum teres patch Laparoscopic pancreatoduodenectomy Portal vein repair Case report

Identification of Seven Novel Mutations in the Acid Alpha-glucosidase Gene in Five Chinese Patients with Late-onset Pompe Disease

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第4期131卷 448-453页

作者： Hua-Xu Liu Chuan-Qiang Pu qiang Shi Yu-Tong Zhang Rui Ban Department of Neurology Chinese People's Liberation Army General Hospital Beijing 100853 China School of Medicine Nankai University Tianjin 300071 China

Background： Pompe disease is a rare lysosomal glycogen storage disorder linked to the acid alpha-glucosidase gene （GAA）. A wide clinical and genetic variability exists between patients from different ethnic populations, and the genotype-phenotype correlations are still not well understood. The aim of this study was to report the clinicopathological and genetic characteristics of five Chinese patients with late-onset Pompe disease （LOPD） who carried novel GAA gene mutations. Methods： Clinical and pathological data of patients diagnosed with glycogen storage disease at our institution from April 1986 to August 2017 were collected, and next-generation sequencing of frozen muscle specimens was conducted. Results： Of the five patients included in the study, the median disease onset age was 13 years, with a median 5 years delay in diagnosis. The patients mainly manifested as progressive weakness in the proximal and axial muscles, while one patient developed respiratory insufficiency that required artificial ventilation. In muscle biopsies, vacuoles with variable sizes and shapes appeared inside muscle fibers, and they stained positive for both periodic acid-Schiff and acid phosphatase staining. Ten GAA gene mutations, including seven novel ones （c.796C〉A, c. 1057C〉T, c. 1201C〉A, c. 1780C〉T, c. 1799G〉C, c.2051C〉A, c.2235dupG）, were identified by genetic tests. Conclusions： The seven novel GAA gene mutations revealed in this study broaden the genetic spectrum of LOPD and highlight the genetic heterogeneity in Chinese LOPD patients.

关键词： Alpha-glucosidase DNA Mutational Analysis Genetic Heterogeneity Glycogen Storage Disease Type Ⅱ

Increased Expression of the NOD-like Receptor Family, Pyrin Domain Containing 3 Inflammasome in Dermatomyositis and Polymyositis is a Potential Contributor to Their Pathogenesis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2016年第9期129卷 1047-1052页

作者： Xi Yin Gen-Cheng Han Xing-Wei Jiang qiang Shi Chuan-Qiang Pu Department of Neurology Chinese People's Liberation Army General Hospital Beijing 100853 China Department of Immunology Institute of Basic Medical Sciences Academy of Military Medical Sciences Beijing 100850 China

Background： Dermatomyositis （DM） and polymyositis （PM） are common inflammatory myopathies whose immunopathogenic mechanisms remain poorly understood. The NOD-like receptor family, pyrin domain containing 3 （NLRP3） inflammasome is a type of cytoplasmic multiprotein inflammasome and is responsible for the activation of inflammatory reactivations. Responding to a wide range of exogenous and endogenous microbial or sterile stimuli, NLRP3 inflammasomes can cleave pro-caspase- 1 into active caspase- 1, which processes the pro-infammatory cytokines pro-interleukin （IL）-1 β and pro-IL-18 into active and secreted IL-1β and I L-18. The NLRP3 inflammasome is implicated in infectious and sterile inflammatory diseases. However, it remains unclear whether it is involved in the pathogenesis of DM/PM, which we aim to address in our research. Methods： In this study, 22 DM/PM patients and 24 controls were recruited. The protein and RNA expression of IL-113, IL-18, NLRP3, and caspase-1 in serum and muscle samples were tested and compared between the two groups. Results： The serum IL-1 β and IL-18 levels were significantly higher in DM/PM patients than those in the controls by enzyme linked immunosorbent assay （EL1SA, DM vs. control, 25.02 ± 8.29 ng/ml vs. 16.49 ± 3.30 ng/ml, P 〈 0.001 ; PM vs. control, 26.49±7.79 ng/ml vs. 16.49 ± 3.30 ng/ml, P 〈 0.001）. Moreover, the real-time quantitative reverse transcription-polymerase chain reaction （qRT-PCR） showed that DM/PM patients exhibited higher RNA expression of IL-lβ, IL-18, and NLRP3 in the muscle （for IL-1 β, DM vs. control, P 0.0012, PM vs. control, P = 0.0021 ; for IL- 18, DM vs. control, P = 0.0045, PM vs. control, P 0.0031 ; for NLRP3, DM vs. control, P = 0.0017, PM vs. control, P 0.0006）. Moreover, the protein expression of NLRP3 and caspase- 1 in muscle samples of DM/PM patients were also significantly elevated compared to that in the muscles of the controls. Conclusions： Our findings demonstrate that the NLRP3 inflammasome is implicated in the pathogenesis of DM/PM. High NLRP

关键词： Autoimmunity Dermatomyositis NOD-like Receptor Family, Pyrin Domain Containing 3 Inflammasome Polymyositis

Dural enhancement detected by magnetic resonance imaging reflecting the underlying causes of cerebral venous sinus thrombosis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2012年第8期125卷 1513-1516页

作者： TIAN Cheng-lin pu Chuan-qiang Department of Neurology Chinese People's Liberation Army General HospitalBeijing 100853China

Dural enhancement detected by magnetic resonance imaging is a common finding in patients with cerebral venous sinus thrombosis （CVST） and is usually interpreted as a change secondary to CVST. We report two cases of CVST with intense and diffuse dural enhancement that resulted from pachymeningitis in one patient and spontaneous intracranial hypotension in another. Pachymeningitis and spontaneous intracranial hypotension were also determined to be the underlying causes of CVST. The clinical data of these two patients are described. In patients with CVST, dural enhancement is not always a secondary change to CVST. It can be a manifestation of the underlying causes of CVST. When diffuse and intense dural enhancement is revealed, sufficient ancillary tests are warranted to rule out other potential patholooical chanoes of the dura mater those can result in CVST.

关键词： cerebral venous sinus thrombosis magnetic resonance imaging pachymeningitis spontaneous intracranial hypotension

Largely Improved Stretch Ductility and β-Form Room-temperature Durability of Poly(vinylidene fluoride) by Incorporating Aliphatic Polyketone

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2018年第11期36卷 1277-1285页

作者： Shui-Qin pu Shuo Guo Ke Wang qiang Fu College of Polymer Science and Engineering Sichuan University State Key Laboratory of Polymer Materials Engineering

In this study, we attempt to prepare a new blending system of poly（vinylidene fluoride）（PVDF） and aliphatic polyketone （POK） by melt compounding, The latter is a promising engineering plastic with comprehensive mechanical performances. When POK acted as minor phase to homogeneously disperse in and intimately contact with PVDF matrix, the brittle tensile behavior of neat PVDF transferred into a remarkably flexible manner （the elongation at break increased for 20 times）, and more interestingly, the room- temperature durability of β-form PVDF in the uniaxially drawn blend film was obviously better than that in the neat PVDF film. Fourier transform infrared spectroscopy revealed that specific dipole interaction existed between CF2 group of PVDF and C=O group of POK. The intermolecular dipolar interaction induced good compatibility in the PVDF/POK blends, as evidently proved by fine two-phase morphology and decreased melting points of POK crystals. Therefore, the good compatibility and interracial enhancement are responsible for the improvement of the stretch ductility and β-form room-temperature durability of the PVDF/POK blends.

关键词： Blend Aliphatic polyketone Dipole interaction Stretch ductility Uniaxially drawn β-PVDF

Synergistic Effects of Gamma Irradiation,Tensile Stress and Moisture on the Radiolysis of Silicone Foam

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2023年第12期41卷 1969-1978,I0011页

作者： pu-Cheng Wang qiang Liu Bo Liu Wei Huang You An Jian-Yong Liu Hong-Bing Chen Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621000China

The present work involves the investigation of the synergistic effects of gamma irradiation,tensile stress and absorbed moisture on the radiolysis behaviors of silicone foams by experiments and theoretical simulations.For both the pristine and dehydrated samples,the permanent tensile set increases with the initial tensile strain.Further analysis uncovers that the dehydrated samples exhibit greater permanent tensile sets,lower further elongation and higher Young’s modulus than the counterparts of the pristine samples with the same initial tensile strain and gamma dose,verifying the vital synergistic effects on crosslinking network and aggregation structures caused by moisture and gamma radiation.The synergistic effects unveiled by reactive molecular dynamics at the atomic scale are due to the moisture-induced neutralization and stabilization of the macromolecular radicals.The steric hindrance of moisture located at the interface of silica and polymer chains also conduces to the observed synergistic effects due to the inhibited crosslinking reactions.

关键词： Silicone foam Synergistic effect Gamma irradiation Tensile stress Moisture

Application of a modified infratemporal fossa type B approach to the resection of lateral skull base tumors

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2020年第18期133卷 2256-2258页

作者： Yu-Bin Xue pu Wang Yin Xia qiang Liu Wen-Yang Zhang Department of Otolaryngology Head and Neck Surgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China

The infratemporal fossa approach was designed for the removal of large tumors located at the temporal bone and lateral skull base.[1]This approach has several subtypes,including types A,B,C,and D.The infratemporal fossa type B(ITFB)approach exposes the petrous apex,clivus,and horizontal segment of the internal carotid artery(ICA)and is used to remove tumors in this area.[2]The classical ITFB approach to fully exposing the horizontal segment of the ICA includes subtotal resection of the petrous bone,removal of the anterior wall of the external auditory canal and zygomatic arch,resection of the articular disc and condylar process of the mandible,downward traction of the mandible,and transection of the mandibular branch of the trigeminal nerve and middle meningeal artery.

关键词： resection tumors auditory

A Novel Mutation of Mitochondrial T14709C Causes Myoclonic Epilepsy with Ragged Red Fibers Syndrome in a Chinese Patient

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第13期131卷 1569-1574页

作者： Rui Ban Jun-Hong Guo Chuan-Qiang Pu qiang Shi Hua-Xu Liu Yu-Tong Zhang Department of Neurology Chinese People's Liberation Army General Hospital Beijing 100853 China Department of Neurology School of Medicine Nankai University Tianjin 300071 China Department of Neurology The First Hospital of Shanxi Medical University Taiyuan Shanxi 030001 China

Background： Myoclonic epilepsy with ragged red fibers （MERRF） syndrome is characterized by myoclonus, generalized epilepsy, cerebellar ataxia, and ragged red fibers （RRFs） in the muscle. T-to-C transition at nucleotide position 14709 in the mitochondrial tRNA glutamic acid （tRNA^Gla） gene has previously been associated with maternally inherited diabetes and deathess. However, the association between MERRF and mitochondrial T14709C mutation （m.TI4709C） has never been reported before. Methods： Clinical information of a 17-year-old patient was collected; muscle biopsy and next-generation sequencing （NGS） of whole mitochondrial and neuromuscular disease panel were then conducted. Finally, sanger sequencing was carried out to confirm the mutations. Results： The patient presented a typical MERRF phenotype with muscle weakness, epileptic seizure, clonic episodes, cerebellar ataxia, and spinal scoliosis. Muscle biopsy showed RRFs which indicated abnormal mitochondrial functions. NGS of whole mitochondrial gene revealed m.TI4709C mutation, confirmed by Sanger sequencing. Conclusion： We present a sporadic patient with typical MERRF presentation carrying the mutation ofm.T14709C, which expanded the spectrum of re.T14709C.

关键词： m.TI4709C Myoclonic Epilepsy with Ragged Red Fibers Syndrome： Novel Mutation