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Surgical treatment and pathologic analysis of posterior lentiglobus with cataract

International Journal of Ophthalmology(English edition) 2011年第5期4卷 572-574页

作者： Guo-Yuan Yang long-qian liu and Chun-Ling liu Department of Ophthalmology West China Hospital of Sichuan University. Chengdu 610041 Sichuan Province China

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Association between lumican gene-1554 T/C polymorphism and high myopia in Asian population:a meta-analysis

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International Journal of Ophthalmology(English edition) 2013年第5期6卷 696-701页

作者： Xuan Liao Xu-Bo Yang Meng Liao Chang-Jun Lan long-qian liu Department of Ophthalmology West China School of MedicineSichuan University Department of Ophthalmology and Optometry North Sichuan Medical College Department of Ophthalmology Affiliated Hospital of North Sichuan Medical College

AIMTo investigate the association between lumican gene -1554 T/C polymorphism and high myopia susceptibility.

关键词： lumican high myopia gene polymorphism meta-analysis

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Relationship between higher-order aberrations and myopia progression in schoolchildren: a retrospective study

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International Journal of Ophthalmology(English edition) 2013年第3期6卷 295-299页

作者： Ning Zhang Xu-Bo Yang Wen-Qiu Zhang long-qian liu Guang-Jing Dong Tao-Wen Chen Meng Liao Xuan Liao Department of Ophthalmology West China Hospital Sichuan University

AIM: To investigate the relationship between higher- order aberration (HOA) and myopic progression in schoolchildren. ·METHODS: Between April 23 2011 and August 29, 2011 in the children’s myopia outpatient clinic of the West China Hospital of Sichuan University, 148 eyes of 74 schoolchildren were reviewed. HOAs for a 6 -mm pupil were measured with an aberrometer. Myopic progression rate was defined according to the change in spherical equivalent refraction (SER) divided by the time span (years). Subjects with myopic progression rate of ≥0.50 diopters (D) were classified as the ’fast’group and the subjects with myopic progression rate of longitudinal study, we aim to verify whether HOA is a risk factor for myopic progression.

关键词： aberration myopia children disease progression refractive errors/etiology

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Refraction difference value variations in children and adolescents with different refractive errors

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International Journal of Ophthalmology(English edition) 2024年第12期17卷 2236-2242页

作者： Da-Wen Wu Ze-Yi Yang Yan Nie He-Ya Ye Liang Chen long-qian liu Guo-Yuan Yang Department of Ophthalmology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Laboratory of Optometry and Visual Science West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

AIM:To evaluate the refraction difference value(RDV)variations in children and adolescents with different refractive errors and analyze its correlation with refractive ***:Participants aged 4-16y with different refractive statuses(hyperopia,emmetropia,myopia)underwent comprehensive eye examinations,including spherical equivalent(SE)refraction,axial length(AL),total RDV(TRDV),and RDVs at various eccentricities(0°-15°,15°-30°,30°-45°)and quadrants(inferior,superior,nasal,temporal).Statistical analysis involved one-way ANOVA for group comparisons and Pearson correlation for examining relationships between SE/AL and *** t-tests compared quadrant-specific RDVs within ***:Significant difference was found in TRDV(P<0.001),RDV15°-30°(P=0.033),RDV30°-45°(P<0.001),RDV-inferior(RDV-I,P<0.001)and RDV-temporal(RDV-T,P<0.001)among hyperopia,emmetropia and myopia *** correlation analysis revealed a negative correlation of SE with TRDV(P=0.001),RDV30°-45°(P=0.004),RDV-I(P=0.047),and RDV-T(P<0.001).The differences between RDV-superior(RDV-S)and RDV-I were statistically significant in all groups(P<0.001 for all)and between RDV-T and RDV-nasal(RDV-N)were statistically significant in hyperopia group(P<0.001).Within the premyopic group,the analysis revealed a negative correlation of SE with RDV-I(P=0.009).Pearson correlation analysis revealed a positive correlation of AL with TRDV(P=0.036),RDV15°-30°(P=0.004),RDV30°-45°(P<0.001),RDV-S(P=0.003),RDV-I(P<0.001),RDV-T(P<0.001),RDV-N(P=0.022),while revealed a negative correlation of AL with RDV0-15°(P=0.018).CONCLUSION:Our study indicates TRDV,RDV30°-45°,RDV-I,RDV-T may relate to refractive development,and a negative correlation between SE and RDV-I in pre-myopic children.

关键词： multispectral refractive topography refraction difference value degrees of myopia children adolescents

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Prenatal ultrasound diagnosis of congenital infantile fibrosarcoma and congenital hemangioma: Three case reports

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World Journal of Clinical Cases 2023年第30期11卷 7403-7412页

作者： Ru-Na Liang Jue Jiang Jie Zhang Xi liu Miao-Yan Ma qian-long liu Li Ma Lei Zhou Yun Wang JuanWang Qi Zhou Shan-Shan Yu Department of Ultrasound The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi'an 710004Shaanxi ProvinceChina Department of Ultrasound Ankang Central HospitalAnkang 725000Shaanxi ProvinceChina Department of Pathology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Pediatric Surgery The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710004Shaanxi ProvinceChina Department of Pathology The Second Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710004Shaanxi ProvinceChina Department of Ultrasound Xi’an Fourth HospitalXi’an 710005Shaanxi ProvinceChina Department of Ultrasound Xijing HospitalXi'an 710032Shaanxi ProvinceChina Department of Ultrasound The Second Hospital of Xi'an Jiaotong UniversityXi'an 710004Shaanxi ProvinceChina

BACKGROUND Congenital infantile fibrosarcoma(CIF)and congenital hemangioma(CH)have similarities on prenatal ultrasound and are *** SUMMARY We report 3 cases of fetuses with superficial hypervascular tumors,confirmed by postnatal pathology as CIF(1 case)and CH(2 cases,including 1 in a twin fetus).In Case 1,a mass with a rich blood supply in the fetal axilla was discovered by prenatal ultrasound at 28+0 wk of *** postpartum pathological diagnosis was CIF,the mass was surgically removed,and the prognosis of the child was *** Case 2,at 23+1 wk of gestation,a mass was discovered at the base of the fetus’s thigh on prenatal *** postpartum pathological diagnosis was *** conservative treatment,the mass shrank *** 3 occurred in a twin *** 30+0 wk of gestation,prenatal ultrasound revealed a bulging mass with a rich blood supply on the abdominal wall of one of the *** weeks later,the affected fetus died,and the unaffected baby was successfully delivered by emergency cesarean *** affected fetus was pathologically diagnosed with *** Prenatal ultrasound can provide accurate information,such as the location,size and blood supply of a surface mass in a *** found similarities between CIF and CH in prenatal ultrasound *** it is difficult to distinguish these conditions by prenatal ultrasound alone,for superficial hypervascular tumors that rapidly increase in size in a short period,close ultrasound monitoring of the fetus is required to quickly address possible adverse outcomes.

关键词： Congenital infantile fibrosarcoma Congenital hemangiomas Prenatal ultrasound Fetal tumor Case report

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Decreased expression of gap junction delta-2 (GJD2) messenger RNA and connexin 36 protein in form-deprivation myopia of guinea pigs

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Chinese Medical Journal 2019年第14期132卷 1700-1705页

作者： Guo-Yuan Yang Feng-Yang liu Xia Li Qiu-Rong Zhu Bing-Jie Chen long-qian liu Department of Opthalmology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Ophthalmology First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

Background:More than ten genome-wide association studies have identified the significant association between the gap junction delta-2 (GJD2) gene and ***,no functional studies have been performed to confirm that this gene is correlated with *** study aimed to observe how this gene changed in mRNA and protein level in the form-deprivation myopia (FDM) animal ***:Four-week-old guinea pigs were randomly divided into two groups:control and FDM groups (n =12 for each group).The right eyes of the FDM group were covered with opaque hemispherical plastic lenses for 3 *** all the animals,refractive status,axial length (AL),and corneal radius of curvature were measured at baseline and 3 weeks later by streak retinoscope,A-scan ultrasonography,and keratometer,*** GJD2 mRNA expression and connexin 36 (Cx36) levels in FDM and control groups were measured by quantitative real-time PCR and Western blot analyses,*** results were compared using independent t test,Mann-Whitney U test,or paired t test.A significance level of P < 0.05 was ***:Three weeks later,the FDM group (form-deprived eyes) showed about a myopic shift of approximately-6.75 (-7.94 to -6.31) D,while the control group remained hyperopic with only a shift of-0.50 (-0.75 to 0.25) D (Z =-3.38,P < 0.01).The AL increased by 0.74 (0.61-0.76) and 0.10 (0.05-0.21) mm in FDM and control groups,respectively (Z =-3.37,P < 0.01).The relative mRNA expression of GJD2 in the FDM group decreased 31.58% more than the control group (t =11.44,P < 0.01).The relative protein expression of CX36 on the retina was lowered by 37.72% in form-deprivation eyes as compared to the controls (t=17.74,P < 0.01).Conclusion:Both the mRNA expression of GJD2 and Cx36 protein amount were significantly decreased in the retina of FDM guinea *** indicates that Cx36 is involved in FDM development,providing compensating evidence for the results obtained from genome-wide associati

关键词： Connexin 36 Myopia Guinea pigs Gap junction

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间歇性外斜视术后中远期眼位的相关因素分析

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国际眼科杂志 2020年第8期20卷 1448-1451页

作者：曾俊刘陇黔四川大学华西医院眼科中国四川省成都市610041 中国四川省自贡市第三人民医院眼科 643020

目的:探讨间歇性外斜视患者术后中远期眼位的影响因素。方法:回顾性分析我院眼科2017-01/2018-08收治的间歇性外斜视患者78例的临床资料,收集患者的斜视类型、手术年龄、术前有无近立体视和斜视度及术后第1d斜视度等资料,探讨术后中远... 详细信息

目的:探讨间歇性外斜视患者术后中远期眼位的影响因素。方法:回顾性分析我院眼科2017-01/2018-08收治的间歇性外斜视患者78例的临床资料,收集患者的斜视类型、手术年龄、术前有无近立体视和斜视度及术后第1d斜视度等资料,探讨术后中远期眼位的影响因素。结果:本研究纳入患者术后中远期眼位正位者47例(60%),其中术前集合不足型患者43例,术后中远期眼位正位者18例(42%);基本型患者31例,术后中远期眼位正位者26例(84%);分开过强型患者4例,术后中远期眼位正位者3例(75%)。单因素分析结果显示,术后中远期眼位正位者与无效者斜视类型、术前视近斜视度具有差异(P<0.05);多因素Logistic回归分析显示,斜视类型(基本型)是影响间歇性外斜视患者术后中远期眼位的危险因素(OR=5.769,95%CI:1.790~18.595,P<0.05)。结论:斜视类型是间歇性外斜视患者术后中远期眼位的独立影响因素,临床应引起足够重视。

关键词：间歇性外斜视术后眼位斜视类型斜视度影响因素

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婴儿眼球震颤综合征的研究进展

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国际眼科杂志 2021年第10期21卷 1716-1719页

作者：潘佳幸刘陇黔四川大学华西医院眼科中国四川省成都市610041 四川大学华西临床医学院中国四川省成都市610041

婴儿眼球震颤综合征(infantile nystagmus syndrome,INS)是一种先天性病理性眼球震颤,以双眼非自主性的共轭摆动和反向视动性眼球震颤为特征表现。INS患者可合并弱视、斜视及斜颈等,常有不同程度的视功能障碍。该病病因尚不明确,且无法... 详细信息

婴儿眼球震颤综合征(infantile nystagmus syndrome,INS)是一种先天性病理性眼球震颤,以双眼非自主性的共轭摆动和反向视动性眼球震颤为特征表现。INS患者可合并弱视、斜视及斜颈等,常有不同程度的视功能障碍。该病病因尚不明确,且无法完全治愈,应尽早对INS进行检查和适当干预。基于国内外对INS的研究成果,本文首先总结了INS目前所知的病因及发生机制;其次,介绍了INS近年提出的检查方法与治疗方案,总结了相关临床实践中存在的问题,并在此基础上,对未来可能的研究方向给出了建议,旨在为临床应用及未来研究方向提供参考。

关键词：婴儿眼球震颤综合征先天性眼球震颤发病机制检查治疗

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Beneficial Effect of Moderately Increasing Hypothermic Machine Perfusion Pressure on Donor after Cardiac Death Renal Transplantation

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Chinese Medical Journal 2018年第22期131卷 2676-2682页

作者： Chen-Guang Ding Pu-Xun Tian Xiao-Ming Ding He-Li Xiang Yang Li Xiao-Hui Tian Feng Han qian-Hui Tai qian-long liu Jin Zheng Wu-Jun Xue Department of Renal Transplantation Nephropathy HospitalThe First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxi 710061China Institute of Organ Transplantation Xi'an Jiaotong UniversityXi'anShaanxi 710061China

Background:Vascular resistance and flow rate during hypotherrnic machine perfusion (HMP)of kidneys is correlated with graft function. We aimed to determine the effects of increasing HMP pressure versus maintaining the initial pressure on kidney transplantation outcomes. Methods:We retrospectively reviewed the data of 76 primary transplantation patients who received HMP-preserved kidneys from 48 donors after cardiac death between September 1,2013,and August 31,*** pressure was increased from 30 to 40mmHg (1mmHg =0.133kPa)in kidneys with poor flow and/or vascular resistance (increased pressure [IP]group;36 patients);otherwise,the initial pressure was maintained (constant pressure group;40 patients).Finally,the clinical characteristics and transplantation outcomes in both groups were assessed. Results:Delayed graft function (DGF)incidence,1-year allograft,patient survival,kidney function recovery time,and serum creatinine level on day 30 were similar in both groups,with improved flow and resistance in the IP *** patients with DGF,kidney function recovery time and DGF duration were ameliorated in the IP *** logistic regression analysis revealed that donor hypertension (odds ratio [OR]:1.43,95%confidence interval [CI]:1.02-2.06,P =0.035),donor terminal serum creatinine (OR:1.27,95%C7:1.06-1.62,P =0.023),warm ischemic time (OR:3.45,95%CI:1.97-6.37,P =0.002),and terminal resistance (OR:3.12,95%CI:1.76-6.09,P =0.012)were independent predictors of *** proportional hazards analysis showed that terminal resistance (hazard ratio:2.06,95%C1:1.32-5.16,P =0.032)significantly affected graft survival. Conclusion:Increased HMP pressure improves graft perfusion but does not affect DGF incidence or 1-year graft survival.

关键词： Delayed Graft Function Donor after Cardiac Death Hypothermic Machine Perfusion Kidney Transplantation

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Rational modulation of fluorophosphate cathode by anionic groups to reduce the polarization behavior for fast-charging sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 509-521页

作者： Xinyuan Wang Fan Zhang Xingyu Zhou qian Wang Changyu liu Yangyang liu Hui Wang Xiaojie liu Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education College of Chemistry & Materials Science Northwest University

Na3V2（PO4）2O2F （VP） is recognized as a promising cathode material for sodium-ion batteries due to its stable structural framework and high specific *** functional theory （DFT） and finite element simulations show that incorporating SO42-into VP decreases its band gap,lowers the migration energy barrier,and ensures a uniform Na+concentration gradient and stress distribution during charge and discharge ***,the average Na+diffusion coefficient of Na3V2（PO4）1.95（SO4）0.05O2F（VPS-1） is roughly double that of VP,leading to enhanced rate capability (80 C,75.5 mAh g-1) and cycling stability (111.0 mAh g-1capacity after 1000 cycles at 10 C current density) for ***-1 exhibits outstanding fast-charging capabilities,achieving an 80%state of charge in just 8.1 *** assembled VPS-1//SbSn/NPC full cell demonstrated stable cycling over 200 cycles at a high 5 C current,maintaining an average coulombic efficiency of 95.35%.

关键词： Anionic group modulation Polarization behavior Fast-charging Sodium-ion battery Fluorophosphate Cathode

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