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Comparison of Rotating Stall Warning by Different Methods for Variable Speed Configurations in a Contra-Rotating Compressor

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Journal of Thermal Science 2024年第4期33卷 1379-1393页

作者： XUE Fei WANG Yan'gang LIU qian WU Tong LIU Hanru School of Power and Energy Northwestern Polytechnical UniversityXi’an710072China

Stall in compressors can cause performance degradation and even lead to *** unacceptable consequences can be avoided by timely monitoring stall inception and taking effective *** paper focused on the rotating stall warning in a low-speed axial contra-rotating ***,the stall disturbance characteristics under different speed configurations were *** results showed that as the speed ratio(RR)increased,the stall disturbance propagation speed based on the rear rotor speed gradually ***,the standard deviation(SD)method,the cross-correlation(cc)method,and the discrete wavelet transform(DWT)method were employed to obtain the stall initiation moments of three different speed *** was found that the SD and cc methods did not achieve significant stall warning results in all three speed ***,the stall initiation moment obtained by the DWT method at RR=1.125 was one period after the stall had fully developed,which was ***,a stall warning method was developed in the present work based on the long short-term memory(LSTM)regression *** applying the LSTM model,the predicted stall initiation moments of three speed configurations were at the 557th,518th,and 333rd revolution,which were44,2,and 74 revolutions ahead of stall onset moments,***,in scenarios where a minor disturbance preceded the stall,the stall warning effect of the LSTM was greatly improved in comparison with the aforementioned three *** contrast,when the pressure fluctuation before the stall was relatively small,the differences between the stall initiation moments predicted by these four methods were not significant.

关键词： contra-rotating compressor stall disturbance stall initiation moment long short-term memory(LSTM) stall warning

Enhancing alkaline water oxidation with NiFe alloy-encapsulated nitrogen-doped vertical graphene array

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Nano Research 2024年第6期17卷 4790-4796页

作者： Jue Nan Beirong Ye Xun He Chen Li Wanli Zhang qian Liu Luming Li Wei Chu Xuping Sun Yongqi Zhang School of Integrated Circuit Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Institute of Fundamental and Frontier Science University of Electronic Science and Technology of ChinaChengdu 611731China Institute for Advanced Study Chengdu UniversityChengdu 610106China College of Chemistry Chemical Engineering and Materials ScienceShandong Normal UniversityJinan 250014China

Advancing efficient and affordable electrocatalysts to boost the oxygen evolution reaction(OER)is pivotal for sustainable green hydrogen ***,we propose the fabrication of nickel-iron alloy nanoparticles-encapsulated on N-doped vertically aligned graphene array on carbon cloth(NiFe@NVG/cc)as a highly active three-dimensional(3D)catalyst electrode for *** 1 M KOH,such NiFe@NVG/cc demonstrates outstanding catalytic performance,necessitating merely overpotential of 245 mV for achieving a current density of 10 mA·cm^(−2),a remarkably low Tafel slope of 36.2 mV·dec^(−1).Furthermore,density functional theory calculations validate that the incorporate of N species into graphene can reinforce the electrocatalytic activity though reducing the reaction energy barrier during the conversion of*O to*OOH *** outstanding performance and structural benefits of NiFe@NVG/cc offer valuable insights for the development of innovative and efficient electrocatalysts for water oxidation.

关键词： NiFe alloy N-doped vertical graphene array electrocatalyst oxygen evolution reaction density functional theory

Prediction of Porous Media Fluid Flow with Spatial Heterogeneity Using Criss-Cross Physics-Informed Convolutional Neural Networks

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1323-1340页

作者： Jiangxia Han Liang Xue Ying Jia Mpoki Sam Mwasamwasa Felix Nanguka Charles Sangweni Hailong Liu qian Li State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China Department of Oil-Gas Field Development Engineering College of Petroleum EngineeringChina University of PetroleumBeijing102249China Exploration Production Research Institute SinopecBeijing102249China Ministry of Energy Tanzania Petroleum Development CorporationTowerDar es Salaam2774Tanzania Ministry of Energy Building Petroleum Upstream Regulatory Authority in Tanzania(PURA)Dar es Salaam11439Tanzania

Recent advances in deep neural networks have shed new light on physics,engineering,and scientific *** the data-centered viewpoint with physical simulation is one of the research *** physicsinformedneural network(PINN)is currently the most general framework,which is more popular due to theconvenience of constructing NNs and excellent generalization *** automatic differentiation(AD)-basedPINN model is suitable for the homogeneous scientific problem;however,it is unclear how AD can enforce fluxcontinuity across boundaries between cells of different properties where spatial heterogeneity is represented bygrid cells with different physical *** this work,we propose a criss-cross physics-informed convolutionalneural network(cc-PINN)learning architecture,aiming to learn the solution of parametric PDEs with spatialheterogeneity of physical *** achieve the seamless enforcement of flux continuity and integration ofphysicalmeaning into CNN,a predefined 2D convolutional layer is proposed to accurately express transmissibilitybetween adjacent *** efficacy of the proposedmethodwas evaluated through predictions of several petroleumreservoir problems with spatial heterogeneity and compared against state-of-the-art(PINN)through numericalanalysis as a benchmark,which demonstrated the superiority of the proposed method over the PINN.

关键词： Physical-informed neural networks(PINN) flow in porous media convolutional neural networks spatial heterogeneity machine learning

Reversibly size-switchable polyion complex micelles for antiangiogenic cancer therapy

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Chinese Chemical Letters 2024年第7期35卷 377-382页

作者： Mengjuan Sun Muye Zhou Yifang Xiao Hailei Tang Jinhua Chen Ruitao Zhang Chunjiayu Li Qi Ya qian Chen Jiasheng Tu Qiyue Wang Chunmeng Sun NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparations and Excipients China Pharmaceutical UniversityNanjing 210009China State Key Laboratory of Natural Medicines China Pharmaceutical UniversityNanjing 211198China Department of Pharmaceutics School of PharmacyChina Pharmaceutical UniversityNanjing 211198China Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics China Pharmaceutical UniversityNanjing 210009China School of Pharmaceutical Science Nanjing Tech UniversityNanjing 211816China

Size is one of the most important characteristics of nanoparticles to influence their biodistribution and antitumoral *** with large sizes have difficulty in deep tumor penetration,while small particles are easily removed from tumor tissues due to the high tumor interstitial fluid *** address these issues,an intelligent core-crosslinked polyion complex micelle(cPCM)with a reversibly sizeswitchable feature was engineered in this *** micelles are consisting of methoxy poly(ethylene glycol)-poly(D,L-lactide)copolymer(mPEG-PLA),mPEG-PLA-(HE)6cc,and mPEG-PLA-(RG)6cc at an optimal mass ratio of 6:1:1 with an antiangiogenic compound,dabigatran etexilate(DE),*** net charge inside the micelles is switchable when exposed to different pH conditions,thereby leading to revisable size-change of ***-loaded micelles(DE@cPCM)can swell and release drugs at the tumor sites with a mildly acidic pH,while they shrink and protect the cargo from leaking into the blood circulation with a neutral *** indicated that DE@cPCM can inhibit tumor angiogenesis in vitro and in vivo,thereby efficiently restraining tumor growth in a 4T1-bearing mouse ***,the sizeswitchable cPCM is a promising nanoplatform for targeting delivery of anticarcinogens into the matrix of tumor tissues.

关键词： Polyion complex micelle Size-switchable Revisable size-change pH response Antiangiogenic cancer

The prognostic value of collateral circulation in coronary chronic total occlusion underwent percutaneous coronary intervention

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Journal of Geriatric Cardiology 2024年第2期21卷 232-241页

作者： Xiao-Ying HU Wei-Xian YANG Chang-Dong GUAN Li-Hua XIE Ke-Fei DOU Yong-Jian WU Jin-Qing YUAN Jie qian Yue-Jin YANG Shu-Bin QIAO Lei SONG Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina National Clinical Research Center for Cardiovascular Diseases BeijingChina Catheterization Laboratories Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

BACKGROUND The prognostic value of coronary collateral circulation(cc)in patients undergoing chronic total occlusion(CTO)percutaneous coronary intervention(PCI)is *** purpose of the study was to assess the prognostic value of current two cc grading systems and their association with long-term outcomes in patients with CTO underwent *** We consecutively enrolled patients with single-vessel CTO underwent PCI between January 2010 and *** patients were categorized into well-developed or poor-developed collaterals group according to angiographic Werner's cc(grade 2 *** 0–1)or Rentrop(grade 3 *** 0–2)grading *** primary endpoint was 5-year cardiac *** Of 2452 enrolled patients,the overall technical success rate was 74.1%.Well-developed collaterals were present in686 patients(28.0%)defined by Werner's cc grade 2,and in 1145 patients(46.7%)by Rentrop grade *** to Werner's cc grading system,patients with well-developed collaterals had a lower rate of 5-year cardiac death compared with those with poordeveloped collaterals(1.6%vs.3.3%,P=0.02),those with suboptimal recanalization was associated with higher rate of 5-year cardiac death compared with optimal recanalization(4.7%vs.0.8%,P=0.01)and failure patients(4.7%vs.1.6%,P=0.12).However,the similar effect was not shown in Rentrop grading *** In patients with the single-vessel CTO underwent PCI,well-developed collaterals by Werner's cc definition were associated with lower rate of 5-year cardiac ***'s cc grading system had a greater prognostic value than Rentrop grading system in patients with CTO underwent PCI.

关键词： coronary collateral occlusion

结肠癌术后化疗感染与细胞免疫及肠道菌群的关系

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中华医院感染学杂志 2024年第5期34卷 738-742页

作者：钱亚萍路芳芳王凌菲汪倩倩雷海云解放军联勤保障部队第903医院血液肿瘤科浙江杭州310013

目的探讨结肠癌(cc)术后化疗感染患者细胞免疫指标变化与肠道菌群构成和多样性的关系。方法回顾性分析2020年1月-2022年1月解放军联勤保障部队第903医院行cc根治术和化疗的107例cc患者的临床资料,根据化疗期间感染情况分为感染组23例... 详细信息

目的探讨结肠癌(cc)术后化疗感染患者细胞免疫指标变化与肠道菌群构成和多样性的关系。方法回顾性分析2020年1月-2022年1月解放军联勤保障部队第903医院行cc根治术和化疗的107例cc患者的临床资料,根据化疗期间感染情况分为感染组23例和非感染组84例。分别于化疗前和化疗3个月后,无菌采集患者痰液、中段尿、粪便及皮肤创面分泌物行病原菌分离鉴定,收集患者化疗3个月后首次新鲜粪便行肠道菌群检测,应用流式细胞仪检测CD_(3)^(+)、CD_(4)^(+)和CD_(8)^(+)表达水平,计算CD_(4)^(+)/CD_(8)^(+)值。比较感染组和非感染组cc术后化疗患者一般资料和化疗前后细胞免疫功能指标水平、肠道菌群构成及多样性。结果化疗后,感染组CD_(3)^(+)、CD_(4)^(+)水平和CD_(4)^(+)/CD_(8)^(+)值低于非感染组,CD_(8)^(+)高于非感染组(P cc术后化疗感染患者细胞免疫功能指标水平降低,肠道有益菌群丰度下降,致病菌丰度升高,肠道菌群多样性下降。

关键词：结肠癌术后化疗感染细胞免疫功能肠道菌群构成和多样性

A citrullinated antigenic vaccine in treatment of autoimmune arthritis

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SCIENCE BULLETIN 2024年第18期69卷 2920-2929页

作者： Jin, Xu Dong, Tianya Wang, qian Xie, Yang Fang, Xiangyu Wei, Chaonan Liu, Shuyan Zheng, Xi Wang, Ping Zhu, Danxue Cao, Lulu Dong, Suwei Fang, Kechi Zhong, Chao Wang, Jing Hu, Fanlei Li, Zhanguo Peking Univ Peoples Hosp Dept Rheumatol & Immunol Beijing 100044 Peoples R China Beijing Key Lab Rheumatism Mech & Immune Diag Beijing 100044 Peoples R China Peking Univ Peking Tsinghua Ctr Life Sci Beijing 100871 Peoples R China Peking Univ Sch Pharmaceut Sci State Key Lab Nat & Biomimet Drugs Beijing 100191 Peoples R China Peking Univ Sch Basic Med Sci Dept Integrat Chinese & Western Med Beijing 100191 Peoples R China Peking Univ Sch Pharmaceut Sci Dept Chem Biol Beijing 100191 Peoples R China Chinese Acad Sci Inst Psychol CAS Key Lab Mental Hlth Beijing 100101 Peoples R China Univ Chinese Acad Sci Dept Psychol Beijing 100049 Peoples R China Peking Univ NHC Key Lab Med Immunol Beijing Key Lab Tumor Syst Biol Inst Syst BiomedDept ImmunolHlth Sci Ctr Beijing 100191 Peoples R China

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease triggered by antigenic peptides with environmental and genetic risk factors. It has been shown that antigen-specific targeting could be a promising therapeutical strategy for RA by restoring immune tolerance to self-antigens without compromising normal immunity. Citrullination of antigens enhances antigenic properties and induces autoimmune responses. Here, we showed that citrullinated antigenic (citAg) vaccine ameliorated collagen-induced arthritis with decreased T-helper 1 (Th1) and Th17 cells, downregulated proinflammatory cytokines including interlukin-6 and tumor necrosis factor-alpha, and inhibited antigen recall responses. B cell receptor sequencing further revealed that citAg vaccine could dampen the dysregulated V(D)J recombination, restoring the immune repertoire. Taken together, the results demonstrated that citAg vaccine might have a therapeutic effect on RA. (c) 2024 Science China Press. Published by Elsevier B.V. and Science China Press. This is an open access article under the cc BY license (http://***/licenses/by/4.0/).

关键词： CitAg Citrullination Collagen type II Therapeutic vaccine Immune tolerance Rheumatoid arthritis RHEUMATOID-ARTHRITIS LUNGS SUPPRESSION TOLERANCE PROTEINS

World Federation of Acupuncture-Moxibustion Societies (WFAS) Clinical Practice Guideline on Acupuncture and Moxibustion: Gastroesophageal Reflux Disease (GERD) recommendation summaries

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WORLD JOURNAL OF ACUPUNCTURE-MOXIBUSTION 2024年第3期34卷 197-203页

作者： Zhang, Xue-ping Zhou, Juan Pan, Wei-bing Huang, Xue Chen, Ruo-han Liu, Zhen-wen Lan, Xin Chen, Chen-chen Fan, qian Kazemi, Amir Hooman Bai, Xing-hua Beijing Univ Chinese Med Sch Acupuncture Moxibust & Tuina Beijing 100105 Peoples R China Andingmen Community Hlth Serv Ctr Beijing 100007 Peoples R China Beijing Univ Chinese Med Dongzhimen Hosp Beijing 100700 Peoples R China Gen Hosp Peoples Liberat Army China Beijing 100094 Peoples R China Beijing Fengtai Dist Hosp Tradit Chinese Med Beijing 100076 Peoples R China Changshu Hosp Chinese Med Changshu 215516 Jiangsu Peoples R China Univ Tehran Med Sci Tehran Iran

The Clinical Practice Guideline on Acupuncture and Moxibustion: Gastroesophageal Reflux Disease (GERD) (WFAS 007.9-2023), officially released by the World Federation of Acupuncture-Moxibustion Societies (WFAS) on October 9, 2023, represents the inaugural acupuncture and moxibustion clinical practice guideline dedicated to GERD globally. This guideline outlines its purpose, scope, target audience, and relevant environments, along with detailing the acupuncture and moxibustion treatment methodology for GERD, as well as the guideline development process and recommendations. This article specifically emphasizes the recommendations of the guideline, highlighting the crucial importance of both the dissemination and adherence to this guideline to standardize acupuncture and moxibustion treatments for GERD. Such standardization plays a pivotal role in the advancement and widespread utilization of acupuncture and moxibustion in the management of GERD. (c) 2024 World Journal of Acupuncture - Moxibustion House. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the cc BY-NC-ND license

关键词： Clinical practice guideline Gastroesophageal reflux disease Esophageal and gastrointestinal motility Acid suppression Acupuncture and moxibustion DISEASE

长江流域不同植被对2022年极端气象干旱事件的响应

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中国环境科学 2024年第9期44卷 5134-5144页

作者：赵乾佐张璇费俊源许杨李冲郝芳华北京师范大学水科学研究院北京100875 北京林业大学水土保持学院北京100083

基于植被对气象干旱事件的响应特征构建了植被敏感性及脆弱性的评估方法:基于长序列降水及潜在蒸散发数据和日诱导叶绿素荧光指数构建日尺度标准化指数,以2022年长江特大气象干旱事件为例,计算相关系数(cc)、累积响应时间(RT)及响应敏感... 详细信息

基于植被对气象干旱事件的响应特征构建了植被敏感性及脆弱性的评估方法:基于长序列降水及潜在蒸散发数据和日诱导叶绿素荧光指数构建日尺度标准化指数,以2022年长江特大气象干旱事件为例,计算相关系数(cc)、累积响应时间(RT)及响应敏感度(RS)评估植被对干旱响应的敏感性;利用历时响应比(DRR)和烈度响应比(IRR)评估植被对干旱事件响应的脆弱性.结果表明:对于2022年长江流域特大气象干旱事件,(1)上游常绿针叶林及草甸敏感性低(中位cc=0.36,0.44;中位RS=-1.72,-1.58);中下游耕地敏感性最高(中位cc=0.68,中位RS=-1.37),稀树及多树草原敏感性高于林地(中位cc:林地=0.41~0.49,多树草原=0.64,稀树草原=0.61;中位RS:林地=-1.61~-1.57,多树草原=-1.44,稀树草原=-1.40).(2)上游常绿针叶林脆弱性高于其他林地(中位DRR:针叶林=1.04,其他林地=0.85~0.97;中位IRR:针叶林=0.94,其他林地:IRR=0.76~0.88);草甸脆弱性高于中下游多树及稀树草原(中位DRR:草甸=1.28,多树草原=0.74,稀树草原=0.88;中位IRR:草甸=1.24,多树草原=0.74,稀树草原=0.80);耕地脆弱性低(中位DRR=0.77IRR=0.72).(3)空间分布上,上游金沙江流域是高脆弱性热点区域;中下游的四川盆地及汉江流域耕地聚集,是高敏感性热点区域.基于研究结论,当极端干旱事件发生时,可根据不同植被的响应特点开展植被监测和恢复措施,从而保护植被不发生退化和永久性损害.

关键词：气象干旱敏感性脆弱性植被响应长江流域