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Long-term Survival Associated with Crizotinib in a Lung Cancer Patient with a Pulmonary Artery Embolism

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Chinese Medical Journal 2018年第1期131卷 111-112页

作者： qian shen Xiao-Qi Dong Jian-Ying Zhou Department of Respiratory Diseases The First Affiliated Hospital of College of Medicine Zhejiang University Hangzhou Zhejiang 310003 China

To the Editor： Venous thromboembolism （VTE）, including deep vein thrombosis and pulmonary embolism, is a common complication in cancer patients, and the overall risk of VTE in patients with a malignancy was 7-fold as high as that for patients without cancer. Herein, we report a case of long-term survival associated with crizotinib in an anaplastic lymphoma kinase （ALK）-positive lung cancer patient with a pulmonary artery embolism.

关键词： Long-term Survival Associated Crizotinib in a Lung Cancer Patient a Pulmonary Artery Embolism

Synergistically enhanced ORR and HER performance on Co-N-C coupled in-situ generated PtCo intermetallic

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Journal of Energy Chemistry 2025年第1期100卷 721-729页

作者： Guanyu Luo Min Song Lulu An Xiao Huang qian Zhang Chenhao Zhang Tao shen Shuang Wang Deli Wang Key Laboratory of Material Chemistry for Energy Conversion and Storage(Huazhong University of Science and Technology)Ministry of Education School of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan 430074HubeiChina

Integrating multi-scale sites in a composite catalyst is vital to realize efficient ***,a synergistic composite catalyst consisting of Co atomic sites and in-situ generated PtCo intermetallic compounds (IMCs)(o-PtCo@CoNC) is proposed through Co pre-anchoring and subsequent impregnation-reduction *** loading of Co atoms provides a chance for in-situ generating PtCo ordered intermetallic *** remaining Co single atoms and PtCo IMCs construct synergistic electrocatalytic *** from the ordered structure,synergistic effect of Pt Co IMCs and Co single atoms,o-PtCo@CoNC exhibits excellent electrocatalytic performance for oxygen reduction reaction (ORR) and hydrogen evolution reaction (HER) with mass activity of 1.21 A mgPt-1(at 0.9 V) and5.70 A mgPt-1(at an overpotential of 100 mV),***,o-PtCo@CoNC delivers negligible loss of half-wave potential and overpotential during long-term stability test in acid solutions,with 13 mV decay after 50,000 potential cycles for ORR and a 2.7 mV decay after 20,000 potential cycles for *** integration strategy of single-atomic sites coupled IMCs paves the way for enhancing the activity and durability of Pt-based electrocatalysts.

关键词： Synergistic effect Intermetallics Single atomic sites Oxygen reduction reaction Hydrogen evolution reaction

Symptomatic adult annular pancreas:report of two cases and a review of the literature

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Hepatobiliary & Pancreatic Diseases International 2005年第3期4卷 468-471页

作者： Pei-Fen Fu Ji-Ren Yu Xiao-Sun Liu qian-Yun shen Shu-Sen Zheng Department of Surgery First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China.

Annular pancreas in adults is a rare embryologic abnormality detected after development of complications. Embryology, diagnosis and treatment strategies for symptomatic adult annular pancreas remain controversial. In this paper we reevaluated these problems in view of the technological and theoretical advances. METHODS: In 2 patients with annular pancreas, one (36-year-old male patient) presenting with duodenal obstruction and duodenal ulcer associated with duodenocolic fistula underwent Billroth II gastrectomy and fistula ectomy and the other(17-year-old male patient) presenting with duodenal obstruction and duodenal ulcer underwent Billroth II gastrectomy. English language literature about annular pancreas etiology, diagnosis and treatment was reviewed. RESULTS:Both of the patients had uneventfully recovered. Abdominal computed tomography, endoscopic retrograde cholangiopancreatography and magnetic resonance cholan-giopancreatography showed typical images of annular pancreas. Duodenal bypass procedure, choledochojejunostomy, endoscopic sphincterotomy or biliary stenting, and pancreatic resection were alternative to treat this sort of anomaly. CONCLUSIONS: Annular pancreas in adults is a rare congenital abnormality, while newer imaging modalities and an index of suspicion may assist in finding more cases. The management of this congenital anomaly should be individualized according to the associated complications.

关键词： pancreas congenital abnormality annular

Image enhancement of color fundus photographs for age-related macular degeneration:the Shanghai Changfeng Study

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International Journal of Ophthalmology(English edition) 2022年第2期15卷 268-275页

作者： Jing-Jing shen Rui Wang Li-Long Wang Chuan-Feng Lyu Shuo Liu Guo-Tong Xie Hai-Luan Zeng Ling-Yan Chen Min-qian shen Xin Gao Huan-Dong Lin Yuan-Zhi Yuan Department of Ophthalmology Zhongshan HospitalFudan UniversityShanghai 200032China Center for Evidence-based Medicine Fudan UniversityShanghai 200032China Pingan Technology(shenzhen)Co. Ltd.Shenzhen 518029Guangdong ProvinceChina Department of Endocrinology and Metabolism Zhongshan HospitalFudan UniversityShanghai 200032China Fudan Institute for Metabolic Diseases Shanghai 200032China

AIM:To develop and evaluate a new fundus image optimization software based on red,green,blue channels(RGB) for the evaluation of age-related macular degeneration(AMD) in the Chinese ***:Fundus images that were diagnosed as AMD from the Shanghai Changfeng Study database were analyzed to develop a standardized optimization *** brightness,contrast,and color balance were *** between central lesion area and normal retinal area under different image brightness,contrast,and color balance were *** optimal optimization parameters were determined based on the visual system to avoid image distortion.A paired-sample diagnostic test was used to evaluate the enhancement *** optical coherence tomography(OCT) was used as the gold *** performances were compared between original images and optimized images using Mc Nemar’s ***:A fundus image optimization procedure was developed using 86 fundus images of 74 subjects diagnosed with *** observing gray-scale images,choroid can be best displayed in red channel and retina in green channel was *** was limited information in blue *** 104 participants were included in the paired sample diagnostic test to assess the performance of the optimization *** the image enhancement,sensitivity increased from 74% to 88%(P=0.008),specificity decreased slightly from 88% to 84%(P=0.500),and Youden index increased by ***:The standardized image optimization software increases diagnostic sensitivity and may help ophthalmologists in AMD diagnosis and screening.

关键词： age-related macular degeneration image enhancement image optimization retina

维普期刊数据库评论

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论黄宗仰与《频伽藏》的校刊及其贡献

世界宗教研究 2009年第4期 41-49页

作者：沈潜常熟理工学院人文学院

近代爱国名僧黄宗仰本着佛法应时救世的精神,亦为推动近代佛教文化复兴事业的发展,顺应近代佛经刊刻事业发展的需要,在哈同夫妇的大力资助下主持校刊《频伽大藏经》,以其独特的选本、取材的广泛、校勘的严谨,以及僧俗联手合作等特点,对... 详细信息

近代爱国名僧黄宗仰本着佛法应时救世的精神,亦为推动近代佛教文化复兴事业的发展,顺应近代佛经刊刻事业发展的需要,在哈同夫妇的大力资助下主持校刊《频伽大藏经》,以其独特的选本、取材的广泛、校勘的严谨,以及僧俗联手合作等特点,对近代佛教文化的复兴有着重要影响。

关键词：黄宗仰《频伽藏》佛法救世佛教革新

乡村治理现代化背景下复合型治理的生成逻辑--以“三元统合”为分析框架

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南京农业大学学报（社会科学版） 2022年第5期22卷 90-101页

作者：沈迁华中科技大学公共管理学院湖北武汉430074

乡村治理现代化转型推动东部沿海乡村形塑复合型治理结构。田野经验表明,乡村社会呈现治理机制的复合型嵌入:常规型事务的行政化运作,形塑乡村科层组织格局;运动型事务的政治域统筹,奠定乡村党委统合制度;内生型事务的自治性回应,构建... 详细信息

乡村治理现代化转型推动东部沿海乡村形塑复合型治理结构。田野经验表明,乡村社会呈现治理机制的复合型嵌入:常规型事务的行政化运作,形塑乡村科层组织格局;运动型事务的政治域统筹,奠定乡村党委统合制度;内生型事务的自治性回应,构建乡村协商治理机制。复合型治理结构不仅衍生“政治-行政-自治”三元统合的治理机制,而且提升乡村实质治理能力,实现规则之治、稳定生态与治理有效。复合型治理是外生型治理事务结构倒逼和政治型治理责任考核取向共同作用的结果;其合理性来源于国家政权合法性的必然要求,以及乡村治理现代化的困境突破。

关键词：复合型治理乡村治理现代化三元统合治理机制

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儿童泌尿道感染诊治规范

中华实用儿科临床杂志 2021年第5期36卷 337-341页

作者：沈茜国家儿童医学中心复旦大学附属儿科医院肾脏科上海201102

泌尿道感染(UTI)是儿童最常见的感染性疾病之一。儿童UTI的临床症状可不典型,需结合尿沉渣分析与尿细菌学检查诊断,必要时需完善影像学评估有无泌尿系统发育畸形等。一旦诊断UTI需给予敏感抗菌药物治疗,抗菌药物选择应结合患儿一般情况... 详细信息

泌尿道感染(UTI)是儿童最常见的感染性疾病之一。儿童UTI的临床症状可不典型,需结合尿沉渣分析与尿细菌学检查诊断,必要时需完善影像学评估有无泌尿系统发育畸形等。一旦诊断UTI需给予敏感抗菌药物治疗,抗菌药物选择应结合患儿一般情况、所在地区耐药发生率、既往用药史、尿细菌学药敏结果综合判断。此外,UTI并膀胱输尿管反流的患儿是否需要预防性抗菌药物治疗仍存在一定争议。现通过查阅、分析儿童UTI的相关指南、共识及临床依据,对儿童UTI的诊断、实验室检查、治疗等进行阐述,旨在为临床医师提供参考。

关键词：泌尿道感染儿童诊断治疗膀胱输尿管反流

村社统筹合作社的嵌入过程、社区基础与治理机制

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北京社会科学 2021年第9期 111-120页

作者：沈迁华中科技大学公共管理学院

当前多数农民合作社与农户生产经营关联度较低,其根源在于没有突破土地细碎化格局、社会化服务壁垒与农户分化结构等关键要素的桎梏。但田野研究发现,村社组织通过政治嵌入、文化嵌入与结构嵌入的方式治理合作社,依托土地集体所有制、... 详细信息

当前多数农民合作社与农户生产经营关联度较低,其根源在于没有突破土地细碎化格局、社会化服务壁垒与农户分化结构等关键要素的桎梏。但田野研究发现,村社组织通过政治嵌入、文化嵌入与结构嵌入的方式治理合作社,依托土地集体所有制、合作社集体经济属性以及村庄层面公共规则,能激活集体治权,回应农户差异化经营需求与村庄产业转型要求,实现组织统筹和分散经营的双重治理机制。作为乡村振兴主体的村社统筹合作社,其功能意义在于保障农户生产的结构性环境;达成三产融合的产业集聚效应;同时解决资源落地的“最后一百米”困境。

关键词：合作社村社组织嵌入治理农村集体经济乡村振兴

功能与伦理兼重:并家婚姻生成的解释机制——基于家庭再生产模式变迁视角

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北京工业大学学报（社会科学版） 2022年第4期22卷 56-67页

作者：沈迁华中科技大学公共管理学院湖北武汉430074

近年来,并家婚姻盛行于中国苏南农村地区,发生于独生子女家庭结构。基于家庭再生产模式变迁视角,选取苏南农村作为田野调研地点,从家庭结构、家庭功能与家庭伦理的互动关系入手,梳理家庭再生产模式的变迁,解释并家婚姻的实践形态、生成... 详细信息

近年来,并家婚姻盛行于中国苏南农村地区,发生于独生子女家庭结构。基于家庭再生产模式变迁视角,选取苏南农村作为田野调研地点,从家庭结构、家庭功能与家庭伦理的互动关系入手,梳理家庭再生产模式的变迁,解释并家婚姻的实践形态、生成逻辑和形成机制。研究发现,并家婚姻是伴随着城市化进程出现的新型婚居模式,既强调简单家庭再生产的伦理导向,也注重扩大化家庭再生产的功能导向,实际上是转型阶段家庭再生产的“功能与伦理兼重”的实践模式。讨论并家婚姻的文化特征和经济理性对社会存在的影响,即孙辈姓氏的争夺、原生家庭差异化关爱与财产“隔代继承”、家庭婚姻的稳定性、原生家庭的权力介入和政策环境的适应问题等。

关键词：家庭功能家庭伦理婚居模式并家婚姻家庭再生产模式