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Will partial splenic embolization followed by splenectomy increase intraoperative bleeding?

World Journal of Gastrointestinal Surgery 2024年第2期16卷 318-330页

作者： long Huang qing-Lin Li qing-Sheng Yu Hui Peng Zhou Zhen Yi Shen qi Zhang Department of No.1 Surgery The First Hospital Affiliated to Anhui University of Traditional Chinese MedicineHefei 230031Anhui ProvinceChina Anhui University of Traditional Chinese Medicine Anhui University of Traditional Chinese MedicineHefei 230038Anhui ProvinceChina Department of Surgery The Second Hospital Affiliated to Anhui University of Traditional Chinese MedicineHefei 230061Anhui ProvinceChina

BACKGROUND Partial splenic embolization(PSE)has been suggested as an alternative to splenectomy in the treatment of ***,some patients may experience recurrence of hypersplenism after PSE and require ***,there is a lack of evidence-based medical support regarding whether preoperative PSE followed by splenectomy can reduce the incidence of *** To investigate the safety and therapeutic efficacy of preoperative PSE followed by splenectomy in patients with cirrhosis and *** Between January 2010 and December 2021,321 consecutive patients with cirrhosis and hypersplenism underwent splenectomy at our *** on whether PSE was performed prior to splenectomy,the patients were divided into two groups:PSE group(n=40)and non-PSE group(n=281).Patient characteristics,postoperative complications,and follow-up data were compared between *** score matching(PSM)was conducted,and univariable and multivariable analyses were used to establish a nomogram predictive model for intraoperative bleeding(IB).The receiver operating characteristic curve,Hosmer-Lemeshow goodness-of-fit test,and decision curve analysis(DCA)were employed to evaluate the differentiation,calibration,and clinical performance of the *** After PSM,the non-PSE group showed significant reductions in hospital stay,intraoperative blood loss,and operation time(all P=0.00).Multivariate analysis revealed that spleen length,portal vein diameter,splenic vein diameter,and history of PSE were independent predictive factors for IB.A nomogram predictive model of IB was constructed,and DCA demonstrated the clinical utility of this *** groups exhibited similar results in terms of overall survival during the follow-up *** Preoperative PSE followed by splenectomy may increase the incidence of IB and a nomogram-based prediction model can predict the occurrence of IB.

关键词： Partial splenic embolization Splenectomy Hypertension,Portal Liver Cirrhosis Intraoperative bleeding

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Unraveling the modulation essence of p bands in Co-based oxide stability on acidic oxygen evolution reaction

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Nano Research 2024年第7期17卷 5922-5929页

作者： Yafei Yang Yihao Xu Haiquan Liu qi Zhang Boling Liu Menghua Yang Huan Dai Zunjian Ke Dong he Xiaobo Feng Xiangheng Xiao Department of Physics Zhongnan Hospital of Wuhan UniversityWuhan UniversityWuhan 430072China School of Physics and Electronic Information Yunnan Normal UniversityKunming 650500China Yunnan Key Laboratory of Opto-electronic Information Technology Kunming 650500China

The oxygen evolution reaction(OER)electrocatalysts,which can keep active for a long time in acidic media,are of great significance to proton exchange membrane water ***,Ru-Co_(3)O_(4)electrocatalysts with transition metal oxide Co_(3)O_(4)as matrix and the noble metal Ru as doping element have been prepared through an ion exchange–pyrolysis process mediated by metal-organic framework,in which Ru atoms occupy the octahedral sites of Co_(3)O_(4).Experimental and theoretical studies show that introduced Ru atoms have a passivation effect on lattice *** strong coupling between Ru and O causes a negative shift in the energy position of the O p-band ***,the bonding activity of oxygen in the adsorbed state to the lattice oxygen is greatly passivated during the OER process,thus improving the stability of matrix *** addition,benefiting from the modulating effect of the introduced Ru atoms on the metal active sites,the thermodynamic and kinetic barriers have been significantly reduced,which greatly enhances both the catalytic stability and reaction efficiency of Co_(3)O_(4).

关键词： p-band modulation oxygen evolution reaction stability acidic oxygen evolution reaction(OER)

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Increased long-distance and homo-trans interactions related to H3K27me3 in Arabidopsis hybrids

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Journal of Integrative Plant Biology 2024年第2期66卷 208-227页

作者： Zhaoxu Gao Yanning Su Le Chang Guanzhong Jiao Yang Ou Mei Yang Chao Xu Pengtao Liu Zejia Wang Zewen qi Wenwen Liu Linhua Sun Guangming he Xing Wang Deng Hang he School of Advanced Agriculture Sciences and School of Life Sciences State Key Laboratory of Protein and Plant Gene ResearchPeking UniversityBeijing 100871China College of Grassland Science Beijing Forestry UniversityBeijing 100083China Peking University Institute of Advanced Agricultural Sciences Shandong Laboratory of Advanced Agricultural Sciences in WeifangWeifang 261325China

In plants,the genome structure of hybrids changes compared with their parents,but the effects of these changes in hybrids remain *** reciprocal crosses between Col×C24 and C24×Col in Arabidopsis using high-throughput chromosome conformation capture assay(Hi-C)analysis,we found that hybrid three-dimensional(3D)chromatin organization had more long-distance interactions relative to parents,and this was mainly located in promoter regions and enriched in genes with heterosis-related *** interactions between euchromatin and heterochromatin were increased,and the compartment strength decreased in *** compartment domain(CD)boundaries,the distal interactions were more in hybrids than their *** the hybrids of CURLY LEAF(clf)mutants clfCol×clfC24and clfC24×clfCol,the heterosis phenotype was damaged,and the long-distance interactions in hybrids were fewer than in their parents with lower ***-seq data revealed higher levels of H3K27me3 in the region adjacent to the CD boundary and the same interactional homo-trans sites in the wild-type(WT)hybrids,which may have led to more long-distance *** addition,the differentially expressed genes(DEGs)located in the boundaries of CDs and loop regions changed obviously in WT,and the functional enrichment for DEGs was different between WT and clf in the longdistance interactions and loop *** findings may therefore propose a new epigenetic explanation of heterosis in the Arabidopsis hybrids and provide new insights into crop breeding and yield increase.

关键词： 3D chromatin organization H3K27me3 homo-trans hybrids long-distanceinteractions

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基于RBF-SVM的拼宽预应力混凝土T梁桥可靠度分析

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内蒙古大学学报（自然科学版） 2018年第4期49卷 431-438页

作者：何启龙邬晓光贺攀殷悦中铁大桥(南京)桥隧诊治有限公司南京210061 长安大学桥梁与隧道陕西省重点实验室西安710064

结合有限元法进行结构可靠度计算时,常采用响应面法和BP神经网络法拟合功能函数的隐式表达式,但这些方法对样本点数量的要求较高,在小样本下的拟合中效果并不理想.因此,结合SVM理论,验证了RBF-SVM法可用于小样本下的功能函数隐式拟合.... 详细信息

结合有限元法进行结构可靠度计算时,常采用响应面法和BP神经网络法拟合功能函数的隐式表达式,但这些方法对样本点数量的要求较高,在小样本下的拟合中效果并不理想.因此,结合SVM理论,验证了RBF-SVM法可用于小样本下的功能函数隐式拟合.研究结果表明:采用SVM法拟合的隐式函数,对规范设计值的预测偏小,但其预测误差符合工程精度要求,可以用于小样本下的拼宽桥隐式函数拟合及可靠度计算;拼宽可有效提高旧梁的结构可靠指标并对拼接附近的旧梁可靠指标增加最为有利.

关键词：拼宽桥支持向量抗弯承载力钢束二次力 T梁可靠指标

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阈值风险下的多企业合作治理污染的演化博弈分析

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运筹与管理 2017年第12期26卷 17-22,45页

作者：王先甲何奇龙全吉武汉大学经济与管理学院湖北武汉430072 武汉理工大学管理学院湖北武汉430072

针对环境污染具有跨区域性,环境资源的公共物品属性,由单一产污企业治理污染物难以取得有效成果,辖区内多个产污企业合作治理是环境保护的必由之路。本文从演化博弈论的研究视角探讨了多个排污企业之间的决策演化过程,建立了多主体演化... 详细信息

针对环境污染具有跨区域性,环境资源的公共物品属性,由单一产污企业治理污染物难以取得有效成果,辖区内多个产污企业合作治理是环境保护的必由之路。本文从演化博弈论的研究视角探讨了多个排污企业之间的决策演化过程,建立了多主体演化博弈模型,并考虑了污染排放总量超过总量阈值时的环境恶化风险,研究阈值风险对产污企业合作治理污染策略选择的影响。研究结果表明,较高的治理成本很大地约束了逐利企业治理污染的行为选择,造成公地悲剧的社会问题。企业治污成本较大背景下,环境阈值风险发生概率越高,越能有效促进合作治理环境策略的演化稳定,合作治理占优于不治理。出于对企业自身初始禀赋的保护,产污企业初始禀赋越大、排污收费率越高,越能有效促进企业治理污染物的积极性。最后,为促进辖区内污染企业合作治理污染提出了政策建议。

关键词：合作治理演化博弈演化稳定策略公共物品博弈

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Functional predictability of universal gene circuits in diverse microbial hosts

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Quantitative Biology 2024年第2期12卷 129-140页

作者： Chenrui qin Tong Xu Xuejin Zhao Yeqing Zong Haoqian M.Zhang Chunbo Lou qi Ouyang long qian Peking-Tsinghua Joint Center for Life Sciences Peking UniversityBeijingChina CAS Key Laboratory of Microbial Physiological and Metabolic Engineering Institute of MicrobiologyChinese Academy of SciencesBeijingChina Bluepha Co. LtdBeijingChina Center for Cell and Gene Circuit Design CAS Key Laboratory of Quantitative Engineering BiologyGuangdong Provincial Key Laboratory of Synthetic GenomicsShenzhen Key Laboratory of Synthetic GenomicsShenzhen Institute of Synthetic BiologyShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhenChina Center for Quantitative Biology Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijingChina

Although the principles of synthetic biology were initially established in model bacteria,microbial producers,extremophiles and gut microbes have now emerged as valuable prokaryotic chassis for biological *** the host range in which designed circuits can function reliably and predictably presents a major challenge for the concept of synthetic biology to *** this work,we systematically characterized the cross-species universality of two transcriptional regulatory modules—the T7 RNA polymerase activator module and the repressors module—in three non-model *** found striking linear relationships in circuit activities among different organisms for both *** model fitting revealed host non-specific parameters defining the universality of both ***,a genetic NOT gate and a band-pass filter circuit were constructed from these modules and tested in non-model *** models employing host non-specific parameters were successful in quantitatively predicting circuit behaviors,underscoring the potential of universal biological parts and predictive modeling in synthetic bioengineering.

关键词： circuit predictability host-independent genetic circuits host-nonspecific parameters parts characterization transcriptional regulatory modules

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互联网众筹平台监管策略的演化博弈分析

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当代财经 2017年第4期 57-66页

作者：王先甲何奇龙全吉武汉大学经济与管理学院湖北武汉430072 武汉理工大学管理学院湖北武汉430072

在互联网众筹市场中,由于项目发起人和消费者之间存在事前信息不对称,导致消费者在选择投资项目的过程中面临较大的风险;而作为中介的众筹平台,对发起人监督机制下的惩罚效用可以有效地规避此类问题。运用演化博弈理论分析了互联网众筹... 详细信息

在互联网众筹市场中,由于项目发起人和消费者之间存在事前信息不对称,导致消费者在选择投资项目的过程中面临较大的风险;而作为中介的众筹平台,对发起人监督机制下的惩罚效用可以有效地规避此类问题。运用演化博弈理论分析了互联网众筹中,具有有限理性的众筹平台和项目发起人策略选择的互动机制,得出如下结论:在不考虑平台和发起人受外界声誉激励时,众筹平台的监管惩罚力度越大,发起人策略演化趋于如实揭示策略的可能性越大;项目发起人欺骗的程度越大,众筹平台策略演化趋于监管策略的可能性越大。反之,消费者资金安全问题将由平台承担其损失。有效实施监管,运用不同程度的惩罚策略,可以有效规制众筹平台项目发起人隐藏产品信息欺骗消费者的行为,引导发起人如实揭示项目类型,减少信息不对称带来的逆向选择,提高消费者参与众筹的积极性。

关键词：互联网众筹逆向选择演化博弈复制动态方程

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污染产业转移下府际间合作治理大气污染的演化博弈分析

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运筹与管理 2020年第4期29卷 86-92页

作者：何奇龙李琴英李晶郑州大学商学院河南郑州450001 郑州大学尤努斯社会企业中心中山大学新华学院管理学院广东东莞523133

大气污染具有跨区域性,府际间合作治理是大气污染防治的必由之路,合作治理中存在“搭治污便车”的困境。由于府际间大气污染治理博弈的具有长期性和动态性,由此建立了多人两策略的演化博弈模型。分别研究,无约束机制和有约束机制两种情... 详细信息

大气污染具有跨区域性,府际间合作治理是大气污染防治的必由之路,合作治理中存在“搭治污便车”的困境。由于府际间大气污染治理博弈的具有长期性和动态性,由此建立了多人两策略的演化博弈模型。分别研究,无约束机制和有约束机制两种情况下地方政府演化稳定策略及其影响因素。考虑到政府间污染产业转移,建立了污染产业转移政府对承接方政府治污补偿机制下的演化博弈模型,分别研究无约束和有约束两种情形下(补偿,治理)策略成为演化稳定均衡状态的条件。研究表明:府际间的合作治理策略选择不会受到外部效应的影响,大气污染治理成本、治理时污染物减排量、不治理时污染物排放增加量、中央政府对治理的奖励和对不治理的惩罚力度是影响地方政府决策的重要因素。将大气质量作为政绩考核的重要指标,提高其权重系数,可有效促使地方政府策略向参与合作治理演化。无约束下自主选择时,最优策略(补偿,治理)不会成为稳定均衡策略,引入中央政府约束后,当经济惩罚在一定范围内,(补偿,治理)成为稳定均衡策略。

关键词：合作治理演化博弈地方政府演化稳定策略

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Quantitative effect of kerogen type on the hydrocarbon generation potential of Paleogene lacustrine source rocks,Liaohe Western Depression,China

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Petroleum Science 2024年第1期21卷 14-30页

作者： Sha-Sha Hui Xiong-qi Pang Fu-Jie Jiang Chen-Xi Wang Shu-Xing Mei Tao Hu Hong Pang Min Li Xiao-long Zhou Kan-Yuan Shi State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Exploration and Development Research Institute PetroChina Liaohe Oilfield CompanyPanjin 124010LiaoningChina

Kerogen types exert a decisive effect on the onset and capacity of hydrocarbon generation of source *** source rocks in the Liaohe Western Depression are characterized by thick deposition,high total organic carbon(TOC)content,various kerogen types,and a wide range of thermal ***,their hydrocarbon generation potential and resource estimation can be *** this study,geochemical tests,numerical analysis,hydrocarbon generation kinetics,and basin modeling were integrated to investigate the differential effects of kerogen types on the hydrocarbon generation potential of lacustrine source *** hydrocarbon generation and expulsion(HGE)models of different kerogen types were established quantitatively upon abundant Rock-Eval/TOC/vitrinite reflectance(R_(o))*** sets of good-excellent source rocks deposited in the fourth(Es4),third(Es3),and first(Es1)members of Paleogene Shahejie Formation,are predominantly types I-II_(1),II_(1)-II_(2),and II-III,*** activation energy of types I-II_(2)kerogen is concentrated(180-230 kcal/mol),whereas that of type III kerogen is widely distributed(150-280 kcal/mol).The original hydrocarbon generation potentials of types I,II_(1),II_(2),and III kerogens are 790,510,270,and 85 mg/g TOC,*** Ro values of the hydrocarbon generation threshold for type I-III source rocks gradually increase from 0.42%to 0.74%,and Ro values of the hydrocarbon expulsion threshold increase from 0.49%to 0.87%.Types I and II_(1)source rocks are characterized by earlier hydrocarbon generation,more rapid hydrocarbon expulsion,and narrower hydrocarbon generation windows than types II_(2)and III source *** kerogen types also affect the HGE history and resource *** types(conventional,tight,and shale oil/gas)and three levels(realistic,expected,and prospective)of hydrocarbon resources of different members in the Liaohe Western Depression are *** suggest that t

关键词： Kerogen type Hydrocarbon generation potential Lacustrine source rocks Liaohe western depression

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Spatial construction of ultrasmall Pt-decorated 3D spinel oxidemodified N-doped graphene nanoarchitectures as high-efficiency methanol oxidation electrocatalysts

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Rare Metals 2024年第1期43卷 186-197页

作者： qi Zhang Min-Min Yan Wen-Fa Du Chen-Yu Yin Jian Zhang Lu Yang Yun-qing Kang Hai-Yan he Hua-Jie Huang College of Mechanics and Materials Hohai UniversityNanjing 210098China New Energy Technology Engineering Lab of Jiangsu Province College of ScienceNanjing University of Posts&Telecommunications(NUPT)Nanjing 210023China International Center for Materials Nanoarchitectonics(WPIMANA) National Institute for Materials ScienceTsukuba 305-0044IbarakiJapan

Direct methanol fuel cell technology recently becomes the focus of both academic and engineering circles,which stimulates the exploitation and utilization of advanced electrode catalysts with high activity and long ***,we demonstrate a robust bottom-up approach to the spatial construction of three-dimensional(3D) spinel manganese-cobalt oxide-modified N-doped graphene nanoarchitectures decorated with ultrasmall Pt nanoparticles(Pt/MnCo_(2)O_(4)-NG) via a controllable selfassembly *** incorporation of MnCo_(2)O_(4)nanocrystals provides abundant hydroxyl sources to promote the oxidative removal of CO-like byproducts on Pt sites,while the existence of 3D porous N-doped graphene networks facilitates the transportation of both ions and electrons in the hybrid system,thus giving rise to remarkable synergetic coupling effects during the methanol oxidation ***,the optimized Pt/MnCo_(2)O_(4)-NG nano architecture expres ses exceptional electrocatalytic properties with a large electrochemically active surface area of 99.5 m^(2)·g^(-1),a high mass activity of1508.3 mA·mg^(-1),strong toxicity resistance and reliable long-term durability,which have obvious competitive advantages over those of conventional Pt/carbon black,Pt/carbon nano tube,Pt/graphene,and Pt/N-doped graphene catalysts with the same Pt usage.

关键词： Platinum MnCo_(2)O_(4) 3D graphene Electrocatalysts Methanol oxidation

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