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Controllability of shock waves in one-dimensional polariton condensates

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Communications in Theoretical Physics 2023年第6期75卷 3-10页

作者： qi-wen wang Jin-ling wang wen wen Ji Lin Hui-jun Li Institute of Nonlinear Physics and Department of Physics Zhejiang Normal UniversityJinhua321004 ZhejiangChina College of Science Hohai UniversityNanjingJiangsu 210098China

In one-dimensional incoherent pumped exciton-polariton condensates,we realize the generation and control of supersonic shock *** choosing a suitable initial input wave,we obtain the region of existence of various shock waves as a function of the phase of the initial wave,the coefficient of polariton interaction,the coefficient of the interaction between polariton and reservoir and the condensation rate and intensity of *** these results,we discuss the effect of different parameters on shock waves composed of two shock waves,and find that the gain and loss will result in a sloping platform between two *** addition,we also consider the effect of the non-adiabatic approximation and the diffusion coefficient of the reservoir on the profiles of the shock *** find that the non-adiabatic approximation will result in some small oscillations on the uniform background,and the platform between two waves becomes flat;however,the diffusion effect of the reservoir will clear these small oscillations and tilt the *** results may pave the way to control shock waves in an incoherent pumped exciton-polariton system.

关键词： shock wave exciton-polariton condensate saturated nonlinearity

Synthesis of ultralong Si_3N_4 nanowires by a simple thermal evaporation method

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Rare Metals 2013年第2期32卷 186-190页

作者： wen-qi wang Xiao-Ping Zou Nan-Jia Zhou Guang Zhu Gui-Ying wang Zhen-Sheng Peng Anhui Key Laboratory of Spintronics and Nano-materials (Cultivating Base) Suzhou University Research Center for Sensor Technology Beijing Key Laboratory for SensorBeijing Information Science and Technology University Department of Materials Science and Engineering Northwestern University Structure Research Laboratory University of Science and Technology of China

Largescale vaporsolid synthesis of ultralong silicon nitride （Si3N4） nanowires was achieved by using simple thermal evaporation of mixture powders of active carbon and monoxide silicon. The products were charac terized by Xray diffraction, scanning electron microscopy, energydispersive Xray spectroscopy, and transmission electron microscopy. The results suggest that the silicon nitride nanowires have a smooth surface, with lengths of up to several hundreds of microns and diameters of 100300 nm. A detailed study of both the chemical and structural composition was performed. Such ultralong sil icon nitride nanowires demonstrate potential applications as materials for constructing nanoscale devices and as reinforcement in advanced composites.

关键词： Si3N4 nanowires Ultralong Thermal evaporation

Structure of a new sterol from the South China sponge Dysidea fragilis

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Chinese Journal of Chemistry 1993年第6期11卷 560-564页

作者： Yong-Li Zhong Jing-Yu Su Long-Mei Zeng Wei Shen qi-wen wang Department of Chemistry Zhongshan University Guangzhou 510275 State Key Laboratory of Bioorganic and Natural Products Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032

A new sterol, 5a-cholesta-8(14),24(25)-diene-3/β, 6a-diol (1) and a known sterol (24Z)- 24-ethyl-cholesta-7(8),24(28)-diene-3β,5a,6β-triol (2) have been isolated from the South China Sea sponge Dysidea fragilis. Th... 详细信息

关键词： Structure of a new sterol from the South China sponge Dysidea fragilis ppm

Fanlian Huazhuo Formula alleviates high-fat diet-induced nonalcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway

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World Journal of Gastroenterology 2024年第30期30卷 3584-3608页

作者： Meng-Yuan Niu Geng-Ting Dong Yi Li qing Luo Liu Cao Xi-Min wang qi-wen wang Yi-Ting wang Zhe Zhang Xi-wen Zhong Wei-Bo Dai Le-Yu Li Pharmacology Laboratory Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese MedicineZhongshan 528400Guangdong ProvinceChina Department of Endocrinology Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese MedicineZhongshan 528400Guangdong ProvinceChina

BACKGROUND Fanlian Huazhuo Formula(FLHZF)has the functions of invigorating spleen and resolving phlegm,clearing heat and purging *** has been identified to have therapeutic effects on type 2 diabetes mellitus(T2DM)in clinical ***-alcoholic fatty liver disease(NAFLD)is frequently diagnosed in patients with ***,the therapeutic potential of FLHZF on NAFLD and the underlying mechanisms need further *** To elucidate the effects of FLHZF on NAFLD and explore the underlying hepatoprotective mechanisms in vivo and in *** HepG2 cells were treated with free fatty acid for 24 hours to induce lipid accumulation cell ***,experiments were conducted with the different concentrations of freeze-dried powder of FLHZF for 24 hours.C57BL/6 mice were fed a high-fat diet for 8-week to establish a mouse model of NAFLD,and then treated with the different concentrations of FLHZF for 10 *** FLHZF had therapeutic potential against lipid accumulation and abnormal changes in biochemical indicators in vivo and in *** experiments verified that FLHZF alleviated abnormal lipid metabolism might by reducing oxidative stress,regulating the AMPKα/SREBP-1C signaling pathway,activating autophagy,and inhibiting hepatocyte *** FLHZF alleviates abnormal lipid metabolism in NAFLD models by regulating reactive oxygen species,autophagy,apoptosis,and lipid synthesis signaling pathways,indicating its potential for clinical application in NAFLD.

关键词： Fanlian Huazhuo Formula Nonalcoholic fatty liver disease Autophagy Apoptosis AMPKα/SREBP-1C signal pathway Oxidative stress

ISOLATION AND STRUCTURES OF FOUR CYCLODIPEPTIDES

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Chinese Chemical Letters 1993年第2期4卷 139-140页

作者： Jing Yu SU Yong Li ZHONG Long Mei ZENG Wei SHEN qi wen wang Department of Chemistry Zhongshan UniversityGuangzhou510275 State Key Laboratory of Bio-organic and Natural Products Chemistry Shanghai Institute of Organic ChemistryShanghai 200032

Three novel interesting polychlorinated cyclodipeptides,designated dyssmide A(1),B(2),C(3)and a known compound,2,3-dihydrodyeamide C(4)were isolated from the sponge Dysidea *** structures were elucidated by spectrosco... 详细信息

关键词： CCI IR ISOLATION AND STRUCTURES OF FOUR CYCLODIPEPTIDES

Enhanced absorption process in the thin active region of GaAs based p-i-n structure

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Chinese Physics B 2021年第9期30卷 542-546页

作者： Chen Yue Xian-Sheng Tang Yang-Feng Li wen-qi wang Xin-Xin Li Jun-Yang Zhang Zhen Deng Chun-Hua Du Hai-qiang Jia wen-Xin wang Wei Lu Yang Jiang Hong Chen Key Laboratory for Renewable Energy Beijing Key Laboratory for New Energy Materials and DevicesBeijing National Laboratory for Condensed Matter PhysicsInstitute of PhysicsChinese Academy of SciencesBeijing 100190China University of Academy of Sciences Beijing 100049China Center of Material and Optoelectronics Engineering University of Academy of SciencesBeijing 100049China Songshan Lake Material Laboratory Dongguan 523808China State Key Laboratory for Infrared Physics Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghai 200083China

The optical absorption is the most important macroscopic process to characterize the microscopic optical transition in the semiconductor materials. Recently, great enhancement has been observed in the absorption of the active region within a p–n junction. In this paper, Ga As based p–i–n samples with the active region varied from 100 nm to 3 μm were fabricated and it was observed that the external quantum efficiencies are higher than the typical results, indicating a new mechanism beyond the established theories. We proposed a theoretical model about the abnormal optical absorption process in the active region within a strong electric field, which might provide new theories for the design of the solar cells,photodetectors, and other photoelectric devices.

关键词： photoelectric p-n junction absorption coefficient

Value of T cell receptor gamma alternate reading frame protein and keratin 5 in endometrial carcinoma

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Chinese Medical Journal 2013年第22期126卷 4260-4264页

作者： ZHAO Li-jun LI Xiao-ping qi wen-juan wang Jian-liu WEI Li-hui Department of Obstetrics & Gynecology Peking University People's Hospital Beijing 100044 China

Background Tumors with different gene expression develop and progress in different ways. To deepen our understanding of the progression in endometrial cancer, and provide a useful tool for accurate diagnosis and prognosis assessment, we identified the new molecular prognostic markers in endometrial carcinoma and analyzed the relationship of them with clinical and pathological features of endometrial carcinoma. Methods Ninety-four cases of endometrial endometrioid adenocarcinoma with complete data from the Peking University People＇s Hospital from 2000 to 2008 and 40 cases of normal endometrium were enrolled. Among these, 30 endometrial endometrioid adenocarcinoma samples of different International Federation of Gynecology and Obstetrics （FIGO） stage were selected for further Agilent genome-wide microarray analysis. Significance analysis of microarrays （SAM） was used to identify genes that are significantly associated with tumor progress. Immunohistochemistry was utilized to identify the genes of interest in endometrial carcinoma and normal endometrium. The relationship between the genes and the age, clinical stage, histological grade, myometrium invaded depth, lymph node metastasis status, and the expression of ER, PR, P53, and PTEN were analyzed by X2 test. Results Analysis between FIGO 1988 stage I and stage III identified a 362-gene ＂progress signature＂; 171 downregulated and 191 up-regulated genes. Among the alterative genes, TARP （T cell receptor gamma alternate reading frame protein） and KRT5 （keratin 5） decreased 3.57 fold and 5.8 fold in FIGO stage III patients. The expression of TARP in endometrial carcinoma increased compared to normal endometrium, while that of KRT5 decreased （P〈0.05）. The expression of TARP and KRT5 decreased when stage, histological grading, myometrium invaded depth increased （P〈0.05）. In the cases with lymph node metastasis, the expression of TARP decreased, while the expression of KRT5 did not differ （both P〈0.05） both. The expression

关键词： endometrial cancer T cell receptor gamma alternate reading frame protein keratin 5

Effects of insulin, insulin-like growth factor-I and -II on proliferation and intracellular signaling in endometrial carcinoma cells with different expression levels of insulin receptor isoform A

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Chinese Medical Journal 2013年第8期126卷 1560-1566页

作者： wang Chun-fang ZHANG Guo ZHAO Li-jun LI Xiao-ping qi wen-juan wang Jian-liu WEI Li-hui Department of Obstetrics and Gynecology Peking UniversityPeople's Hospital Beijing 100044 China

Background Hyperinsulinemia, insulin-like growth factor （IGF）-I and -Ⅱ （IGF-Ⅱ） are associated with increased risk of endometrial carcinoma. Insulin receptor isoform A （IR-A） is more frequently expressed in endombtrial carcinoma than in normal endometrial tissues. To better understand their roles in endometrial carcinoma, we investigated the effects of insulin, IGF-I, and IGF-II in endometrial carcinomas cells with different IR-A expression levels. Methods To explore the role of IR-A in mediating the activity of IGF-I, IGF-II, and insulin, we investigate the cellular proliferation of endometrial carcinoma cell lines RL95-2 and RL95-2-1R-A by MTS assays. Then we examined the protein kinase Akt phosphorylation and extracellular signal-regulated kinase （ERK） 1/2 phosphorylation in both cell lines by Western blotting. The effect of IGF-II and AG1024 on cell cycle progression and apoptosis was assessed by fiowcytometry. To examine whether the effects of IGFs were mediated by IR-A, we blocked IGF-I receptor （IGF-IR） in both cell lines using AG1024, an IGF-IR-specific inhibitor. Results IGF-I and IGF-II significantly enhanced proliferation of both cell lines （P 〈0.05）. By contrast, insulin significantly increased proliferation of RL95-2-1R-A cells only （P 〈0.05）. IGF-I and IGF-II significantly increased pAkt levels in RL95-2 cells and pERK1/2 levels in RL95-2-1R-A cells （all, P 〈0.05）. Insulin increased pERK1/2 levels in RL95-2-1R-A cells only （P 〈0.05）. LY294002 and PD98059 inhibited the specific signaling activities and cellular proliferation. After AG1024 pretreatment, neither IGF-I nor IGF-II affected pAkt levels in RL95-2 cells. IGF-II, but not IGF-I, increased pERK1/2 levels in RL95-2-1R-A cells. After AG1024 pretreatment, the proliferation rate and DNA content corresponding to the S phase increased and apoptosis decreased significantly in IGF-II-treated RL95-2-1R-A cells only （P 〈0.05）. Conclusions The proliferation effect of insulin is mediated by IR-A. When IR-A do

关键词： endometrial carcinoma, insulin receptor isoform A insulin, insulin-like growth factor-I insulin-like growth factor-Ⅱ

Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles

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Neural Regeneration Research 2025年第4期20卷 1124-1134页

作者： Yanting Liu Wei Huang Jiayi wen Xin Xiong Ting Xu qi wang Xiusheng Chen Xianxian Zhao Shihua Li Xiaojiang Li Weili Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan UniversityJinan UniversityGuangzhouGuangdong ProvinceChina

The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal ***,it remains largely unclear how PINK1 and Parkin are expressed in mammalian *** has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small *** this issue is critical for elucidating the in vivo roles of PINK1 and ***,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate *** the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate *** found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey ***1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable *** double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial *** findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage.

关键词： neurodegeneration Parkin Parkinson’s disease PINK1 subcellular distribution