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Prevalence and outcomes of pancreatic cystic neoplasms in liver transplant recipients

World Journal of Gastroenterology 2017年第48期23卷 8526-8532页

作者： Ken Liu Vikram Joshi Louise van Camp qi-wei yang Judith E Baars Simone I Strasser Geoffrey W McCaughan Avik Majumdar Payal Saxena Arthur J Kaffes Sydney Medical School The University of Sydney AW Morrow Gastroenterology and Liver Centre Royal Prince Alfred Hospital Department of Radiology Royal Prince Alfred Hospital

AIM To determine the prevalence,characteristics and clinical course of pancreatic cystic neoplasms(PCNs) in liver transplantation(LT) *** We retrospectively studied consecutive patients who underwent LT between January 1998 to April 2016. Clinical and laboratory data were obtained from patient medical records. Imaging findings on computed tomography and magnetic resonance cholangiopancreatography were reviewed by two *** During the study period,872 patients underwent cadaveric LT. Pancreatic cysts were identified in 53/872(6.1%) and 31/53(58.5%) were PCNs [28 intraductal papillary mucinous neoplasm(IPMN),2 mucinous cystic neoplasm(MCN),1 serous cystadenoma]. Patients with PCNs exhibited less male predominance(55% vs 73%,P = 0.03) compared to patients without pancreatic cysts. Thirteen patients(42%) were diagnosed with PCN pre-LT while 18 patients(58%) developed PCN post-LT. The median size of PCNs was 13 mm [interquartile range(IQR) 10-20 mm]. All IPMNs were side-branch type. Most PCNs were found in the head and body of pancreas(37% each),followed by the tail(25%). Five patients underwent further evaluation with endoscopic ultrasound. Progress imaging was performed on 81% of patients. PCNs remained stable in size and number in all but 2 patients. During a median follow up of 39 mo(IQR 26-58 mo),the 2(6%) patients with MCN underwent pancreatectomy. No PCN patient developed pancreatic adenocarcinoma,while 5 died from illnesses unrelated to the PCN. Among patients without PCN,1/841(0.1%) developed pancreatic *** The prevalence of PCNs in LT recipients was similar to the general population(3.6%,31/872). Side-branch IPMNs do not appear to have accelerated malignant potential in post-LT patients,indicating the current surveillance guidelines are applicable to this group.

关键词： Pancreatic cystic neoplasm Intraductal papillary mucinous neoplasm Mucinous cystic neoplasm Liver transplantation Pancreatic adenocarcinoma Immunosuppression

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Brain Abscess Caused by Bacillus megaterium in an Adult Patient

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Chinese Medical Journal 2015年第11期128卷 1552-1554页

作者： Fu-Ping Guo Hong-wei Fan Zheng-Yin Liu qi-wei yang Yi-Jia Li Tai-Sheng Li Department of Infectious Disease Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing 100730 China Department of Laboratory Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing 100730 China

Bacillus megaterium, a Gram-positive, aerobic, spore-forming, rod-shaped bacterium, has been found in widely diverse habitats and has been widely used as a source of recombinant protein in the industry. With a cell le... 详细信息

关键词： Bacillus Megaterium Infection Brain Abscess

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Improved closure techniques for laparoscopic partial nephrectomy in moderately complex renal cell carcinoma

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Chinese Medical Journal 2021年第2期134卷 228-230页

作者： qi-wei yang Xiu-Wu Pan Jian-qing Ye Chuan-Min Chu Fa-Jun Qu Lin Li wei yang Lei Wang Si-Shun Gan Xin-Gang Cui Department of Urology The Third Affiliated Hospital of Naval Military Medical University(Eastern Hepatobiliary Surgery Hospital)Shanghai 201805China Department of Urology Gongli HospitalShanghai 200135China Department of Urology Changzheng HospitalNaval Military Medical UniversityShanghai 200003China

Laparoscopic partial nephrectomy(LPN)as a minimally invasive nephron-sparing surgery is gradually becoming the preferred surgical treatment for T1a renal carcinoma since it yields faster post-operative recovery and equivalent oncological outcomes to radical nephrectomy.[1]However,it is difficult to perform LPN for complex renal tumors,resulting in a longer warm ischemic time(WIT),which consequently affects the recovery of post-operative renal function.[2]With the development of laparoscopic instruments and techniques and the accumulating experience of surgeons,the WIT during LPN may be shortened using anatomy-based early unclamping(EUC)[1]after the placement of one or two running sutures on the tumor *** this study,we improved the closure techniques for LPN using EUC in patients with complex renal tumors and assessed their effectiveness.

关键词： anatomy operative closure

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Catalytic properties of Cu-ZSM-5 in the trichloroethylene （TCE） combustion with air in fixed-bed system

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Journal of Environmental Science and Engineering 2009年第3期3卷 17-23页

作者： XU Cheng-hua LIU Chuan-qi HAO Tian-wei yang Wen LIU Jian-ying LIU Sheng-yu College of Resources and Environment Chengdu University of lnformation Technology Chengdu 610225 China

Cu-ZSM-5 molecular sieves were prepared by the ion-exchange of NH4-ZSM-5 with Cu^2＋ ions in Cu（NO3）2 solution, and was characterized by diffuse reflectance ultraviolet-visible spectroscopy （DRS-UV-vis）, fourier transform infrared spectroscopy （FT-IR） and X-ray powder diffraction （XRD） techniques. And at same time, the catalytic activity of the obtained Cu-ZSM-5 in the trichloroethylene （TCE） combustion with air in the fixed-bed system was also investigated in the present work. The results indicated that the copper content in Cu-ZSM-5 was increased with the increasing Cu2＋ concentration in ion-exchange solution, and however the catalytic activity was not always increased with the copper content in Cu-ZSM-5. It was found that Cu-ZSM-5, prepared with 0.091mol/L of Cu^2＋ solution, exhibited the best catalytic activity in TCE combustion. In combination with the characterization results by DRS-UV-vis and FT-IR techniques, it was deduced that the catalytic active species of Cu-ZSM-5 in TCE combustion with air was the skeletal copper of molecular sieves.

关键词： triehloroethylene (TCE) catalytic combustion ion-exchange Cu-ZSM-5 skeletal copper

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Surgical treatment for Nevin stage IV and V gallbladder carcinoma: report of 70 cases

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Hepatobiliary & Pancreatic Diseases International 2005年第4期4卷 589-592页

作者： wei-Dong Xiao,Cheng-Hong Peng,Guang-Wen Zhou,wei-Ding Wu, Bo-Yong Shen, Ji-qi Yan,wei-Ping yang and Hong-wei Li Department of Surgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China First author’s present address: Deparment of General Surgery, the First Affiliated Hospital, Nanchang University, Nanchang 330006, China Department of Surgery Ruijin Hospital Shanghai Second Medical University Shanghai 200025 China.

BACKGROUND: The role of aggressive surgery for end-stage gallbladder carcinoma is controversial. This retrospective study was designed to evaluate the outcome of surgical treatment for Nevin stage Ⅳ and Ⅴ gallbladder carcinoma at a single institution. METHODS: A retrospective analysis was made on 70 patients with Nevin stage Ⅳ and Ⅴ gallbladder carcinoma undergoing surgical treatment from January 1993 to June 2004. RESULTS: There were 22 cases of stage Ⅳ and 48 of stage V. Cholecystectomy was performed in 37 cases with a resection rate of 53%,9 cases received radical resection, 13 extended radical resection, and 15 palliative resection. The curative resection rate was 31% and the morbidity rate was 36%. Postoperative 1-, 3-, 5-year survival rates of curative and palliative resection were 69%, 33%, 8% and 27%, 13%, 0, respectⅣely (P <0.01). The 1- and 3-year survival rates of patients undergoing exploratory laparotomy only were 3% and 0, respectively. CONCLUSIONS: Nevin stage Ⅳ and Ⅴ gallbladder carcinoma should be treated by aggressive surgery. Curative resection is promising in the improvement of long-term survⅣal rate.

关键词： gallbladder carcinoma surgical procedure

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Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles

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Neural Regeneration Research 2025年第4期20卷 1124-1134页

作者： Yanting Liu wei Huang Jiayi Wen Xin Xiong Ting Xu qi Wang Xiusheng Chen Xianxian Zhao Shihua Li Xiaojiang Li weili yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan UniversityJinan UniversityGuangzhouGuangdong ProvinceChina

The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal ***,it remains largely unclear how PINK1 and Parkin are expressed in mammalian *** has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small *** this issue is critical for elucidating the in vivo roles of PINK1 and ***,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate *** the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate *** found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey ***1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable *** double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial *** findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage.

关键词： neurodegeneration Parkin Parkinson’s disease PINK1 subcellular distribution

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基于熵权-模糊综合评价法的众包物流服务质量评价模型构建

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中小企业管理与科技 2020年第16期4卷 164-170页

作者：韦齐阳上海大学上海200444

众包物流模式作为解决各大电商与物流企业的“最后三公里”配送运力问题的钥匙,其在蓬勃发展的同时也出现了很多服务质量问题。为帮助众包物流企业提升服务质量,促进众包物流行业健康发展,论文结合众包物流服务流程与特点,系统地分析了... 详细信息

众包物流模式作为解决各大电商与物流企业的“最后三公里”配送运力问题的钥匙,其在蓬勃发展的同时也出现了很多服务质量问题。为帮助众包物流企业提升服务质量,促进众包物流行业健康发展,论文结合众包物流服务流程与特点,系统地分析了众包物流服务质量的影响因素。最终构建了以可靠性、信息性、便利性、移情性、时效性、经济性、安全性、创新性为一级评价指标,内含29个二级评价指标的众包物流服务质量评价指标体系。以此为基础,构建了基于熵权-模糊综合评价法的综合评价模型,并选取美团为研究对象进行了实证分析。结果表明,基于熵权-模糊综合评价法的众包物流服务质量评价模型能够有效应用于实践,评价结果科学合理,具有较强的实用性。

关键词：众包物流服务质量熵权-模糊综合评价法评价模型美团

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白马河特大桥大直径钻孔桩施工

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桥梁建设 2006年第A01期36卷 74-76页

作者：卫启阳熊南京中铁大桥局集团第三工程有限公司广东广州510800

白马河特大桥是温福铁路上的一座特大桥,该桥水中基础多,工程地质复杂,介绍在复杂地质条件下大直径钻孔桩的施工。

关键词：钻孔桩钢护筒冲孔桥梁施工

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Prediction and stratification for the surgical adverse events after minimally invasive esophagectomy:A two-center retrospective study

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World Journal of Gastroenterology 2025年第3期31卷 50-61页

作者： qi-Hong Zhong Jiang-Shan Huang Fei-Long Guo Jing-Yu Wu Mao-Xiu Yuan Jia-Fu Zhu Wen-wei Lin Sui Chen Zhen-yang Zhang Jiang-Bo Lin Department of Thoracic Surgery Fujian Medical University Union HospitalFuzhou 350001Fujian ProvinceChina The Graduate School Fujian Medical UniversityFuzhou 350001Fujian ProvinceChina Department of Thoracic Surgery Affiliated Hospital of Jinggangshan UniversityJi’an 343000Jiangxi ProvinceChina

BACKGROUND Minimally invasive esophagectomy(MIE)is a widely accepted treatment for esophageal cancer,yet it is associated with a significant risk of surgical adverse events(SAEs),which can compromise patient recovery and long-term *** preoperative identification of high-risk patients is critical for improving *** To establish and validate a risk prediction and stratification model for the risk of SAEs in patients with *** This retrospective study included 747 patients who underwent MIE at two centers from January 2019 to February *** were separated into a train set(n=549)and a validation set(n=198).After screening by least absolute shrinkage and selection operator regression,multivariate logistic regression analyzed clinical and intraoperative variables to identify independent risk factors for SAEs.A risk stratification model was constructed and validated to predict the probability of *** SAEs occurred in 10.2%of patients in train set and 13.6%in the validation *** with SAE had significantly higher complication rate and a longer hospital stay after *** key independent risk factors identified included chronic obstructive pulmonary disease,a history of alcohol consumption,low forced expiratory volume in the first second,and low albumin *** stratification model has excellent prediction accuracy,with an area under the curve of 0.889 for the training set and an area under the curve of 0.793 for the validation *** The developed risk stratification model effectively predicts the risk of SAEs in patients undergoing MIE,facilitating targeted preoperative interventions and improving perioperative management.

关键词： Surgical adverse events Minimally invasive esophagectomy Esophageal cancer Stratification model Perioperative management

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Correlation analyse between thyroid hormone levels and severity of schizophrenia symptoms

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World Journal of Psychiatry 2025年第1期15卷 63-71页

作者： qi-Hui Jiang wei-Dong Gong Department of Endocrinology and Metabolism Hengyang Central HospitalHengyang 421000Hunan ProvinceChina Breast Tumor Surgical Outpatient Hengyang Central HospitalHengyang 421000Hunan ProvinceChina

BACKGROUND The imbalance of hormone levels in the body is closely related to the occurrence and progression of schizophrenia,especially thyroid *** To study the relationship between triiodothyronine(T3),thyroxine(T4),free T3(FT3),free T4(FT4),thyroid stimulating hormone(TSH)and *** In this study,100 schizophrenia patients were selected from our hospital between April 2022 and April *** clinical data were analyzed *** on the Positive and Negative Syndrome Scale(PANSS)score,patients were divided into mild(1-3 points,n=39),moderate(4 points,n=45),and severe groups(5-7 points,n=16).Additionally,55 healthy individuals served as a control *** blood samples were collected to measure T3,T4,FT3,FT4,TSH,and cortisol concentrations,analyzing their relationship with PANSS *** The serum levels of T3,FT3,FT4,TSH and cortisol in the schizophrenia group were lower than those in the control group(P<0.05).With the increase of the severity of the disease,the concentrations of T3 and T4 decreased,while the con-centrations of TSH and cortisol increased(P<0.05).The concentrations of TSH and cortisol were positively correlated with the PANSS score,while T3 and T4 were negatively correlated with the PANSS score(P<0.05).The receiver ope-rating characteristic curve results showed that T3,T4,TSH,and cortisol had good efficacy in the diagnosis of *** results showed that decreased T3 level,decreased T4 level,decreased TSH level and increased cortisol level may be independent risk factors for *** Thyroid hormone levels are associated with the severity of schizophrenia symptoms,which can provide new solutions for the diagnosis and treatment of schizophrenia.

关键词： Thyroid hormone Schizophrenia Symptom severity Positive and Negative Syndrome Scale score Cortisol

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