检索结果-南通市图书馆

A Fault-tolerance Estimating Method for Ionosphere Corrections in Satellite Navigation System

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2011年第6期24卷 749-755页

作者： gao Shuliang LI rui HUANG Zhigang School of Electronics and Information Engineering Beihang University Beijing 100191 China

Aiming to the reliable estimates of the ionosphere differential corrections for the satellite navigation system in the presence of the ionosphere anomaly, a fault-tolerance estimating method, which is based on the distributed Kalman filtering, is proposed. The method utilizes the parallel sub-filters for estimating the ionosphere differential corrections. Meanwhile, an infinite norm （IN） method is proposed for the detection of the ionosphere irregularity in the filter processing. Once the anomaly is detected, the sub-filter contaminated by the anomaly measurements will be excluded to ensure the reliability of the estimates. The simulation is conducted to validate the method and the results indicate that the anomaly can be found timely due to the novel fault detection method based on the infinite norm. Because of the parallel sub-filter architecture, the measurements are classified by the spatial distribution so that the ionosphere anomaly can be positioned and excluded more easily. Thus, the method can provide the robust and accurate ionosphere differential corrections.

关键词： differential corrections ionosphere anomaly Kalman filter fault-tolerance fault detection

The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi Li Jing Xue Yuejia Ma Ke Ye Xue Zhao Fangliang Ge Feifei Zheng Lulu Liu Xu gao Dayong Wang qing Xia Department of Biochemistry and Molecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic Medical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic Medical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Key Laboratory of Heilongjiang Province for Genetically Modified Animals Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational Medicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be a

关键词： Alzheimer's disease cell self-renewal central nervous system memory microglia nerve regeneration neurodegenerative diseases neurogenesis RNA methylation

Multi-scale analysis on the pulverized coal flow behaviors under high,pressure dense-phase pneumatic conveying

在线全文

学校读者我要写书评

暂无评论

Particuology 2022年第1期20卷 107-114页

作者： Heming gao Xiaojuan Wang qi Chang School of Mechanical and Precision Instrument Engineering Xi'an University of TechnologyXi'an 710048China

To deeply knowledge of the flow behaviors of pulverized coal particles in dense gas-solid two-phase flow,a multi-scale analysis method based on electrostatic sensor array is applied for the multi-scale characterization of flow behaviors of dense gas-solid *** experimental results indicate that:for steady flow,with the increment of conveying pressure difference,the individual particles increase and the particle clusters decrease,the individual particle distribution is always inhomogeneous but the particle cluster distribution tends to be more homogeneous over the cross-section of pipe,while the average flow behavior of pulverized coal particles is always in the relatively static *** unsteady flow,the average flow behavior of pulverized coal particles is dynamic,and the flow behaviors of the multi-scale flow structures over the cross-section of pipe are all significantly ***,the effect of particle size on flow behavior of pulverized coal is also investigated and validated.

关键词： Dense-phase pneumatic conveying Pulverized coal Multi-scale Particle charging

Towards designing efficient catalyst for hydrogen oxidation reaction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2020年第10期39卷 1107-1109页

作者： rui-Jie gao Ji-Jun Zou Key Laboratory for Green Chemical Technology of the Ministry of Education School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China Collaborative Innovative Center of Chemical Science and Engineering(Tianjin) Tianjin 300072China

Anion exchange membrane fuel cells(AEMFCs)have attracted increasing research efforts in the past decade due to the advantageous nature of using Pt-free catalysts and cheap components that bring its cost closer to the ... 详细信息

关键词： catalyst closer designing

A triple-exposure color PIV technique for pressure reconstruction

在线全文

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2017年第1期60卷 1-15页

作者： WANG ZhongYi gao qi WANG JinJun Key Laboratory of Fluid Mechanics Ministry of Education Beijing University of Aeronautics and Astronautics Beijing 100191 China

The study developed a triple-exposure color particle image velocimetry(TE-CPIV) technique associated with pressure reconstruction, and validated its feasibility. A light source with the three primary colors of red, green, and blue(R, G, and B) is produced in a time sequence by a liquid crystal display(LCD) projector. Particle images at three different instants under the color illuminations are captured in one snapshot using a color digital single-lens reflex(SLR) camera with a complementary metal-oxide semiconductor(CMOS) sensor. A contamination correction algorithm based on a specific calibration is performed on the different color layers(R layer, G layer, and B layer) of the raw color image to reduce the contaminated intensity of each color illumination on the other two color layers. The corrected intensity generates three new color layers, from which a standard cross-correlation process in the classical PIV method is used to obtain two velocity fields. Eventually, an instantaneous pressure field is reconstructed from the two velocity fields. The feasibility of TE-CPIV was tested by two experiments with a solid body rotation flow and a cylinder wake flow. The results show acceptable accuracy and robustness of the new technique. The idea of the TE-CPIV is believed to provide a simple and effective way of estimating a pressure field with low cost and high convenience.

关键词： triple exposures color PIV pressure reconstruction

Nanomaterials-mediated lysosomal regulation:a robust protein-clearance approach for the treatment of Alzheimer’s disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 424-439页

作者： Mengqi Hao Jianjian Chu Tinglin Zhang Tong Yin Yuankai Gu Wendanqi Liang Wenbo Ji Jianhua Zhuang Yan Liu Jie gao You Yin Department of Neurology Second Affiliated Hospital of Naval Medical University(Shanghai Changzheng Hospital)ShanghaiChina School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Changhai Clinical Research Unit Shanghai Changhai HospitalNaval Medical UniversityShanghaiChina Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Neurology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Alzheimer’s disease is a debilitating,progressive neurodegenerative disorder characterized by the progressive accumulation of abnormal proteins,including amyloid plaques and intracellular tau tangles,primarily within the ***,crucial intracellular organelles responsible for protein degradation,play a key role in maintaining cellular *** studies have suggested a link between the dysregulation of the lysosomal system and pathogenesis of neurodegenerative diseases,including Alzheimer’s *** the normal physiological function of lysosomes hold the potential to reduce the pathological burden and improve the symptoms of Alzheimer’s ***,the efficacy of drugs in treating Alzheimer’s disease is limited,with major challenges in drug delivery efficiency and ***,nanomaterials have gained widespread use in Alzheimer’s disease drug research owing to their favorable physical and chemical *** review aims to provide a comprehensive overview of recent advances in using nanomaterials(polymeric nanomaterials,nanoemulsions,and carbon-based nanomaterials)to enhance lysosomal function in treating Alzheimer’s *** review also explores new concepts and potential therapeutic strategies for Alzheimer’s disease through the integration of nanomaterials and modulation of lysosomal *** conclusion,this review emphasizes the potential of nanomaterials in modulating lysosomal function to improve the pathological features of Alzheimer’s *** application of nanotechnology to the development of Alzheimer’s disease drugs brings new ideas and approaches for future treatment of this disease.

关键词： Alzheimer’s disease autophagy dysfunction lysosomal acidification lysosomal system nanomaterials neurodegenerative diseases

Metal phosphides and borides as the catalytic host of sulfur cathode for lithium–sulfur batteries

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2022年第5期29卷 990-1002页

作者： rui gao Zhenyu Wang Sheng Liu Guangjie Shao Xueping gao College of Environmental and Chemical Engineering Yanshan UniversityQinhuangdao 066004China School of Materials Science and Engineering Nankai UniversityTianjin 300350China

Lithium−sulfur batteries are one of the most competitive high-energy batteries due to their high theoretical energy density of _(2)600 W·h·kg^(−1).However,their commercialization is limited by poor cycle stability mainly due to the low intrinsic electrical conductivity of sulfur and its discharged products(Li_(2)S_(2)/Li_(2)S),the sluggish reaction kinetics of sulfur cathode,and the“shuttle effect”of soluble intermediate lithi-um polysulfides in ether-based *** address these challenges,catalytic hosts have recently been introduced in sulfur cathodes to en-hance the conversion of soluble polysulfides to the final solid products and thus prevent the dissolution and loss of active-sulfur *** this review,we summarize the recent progress on the use of metal phosphides and borides of different dimensions as the catalytic host of sulfur cathodes and demonstrate the catalytic conversion mechanism of sulfur cathodes with the help of metal phosphides and borides for high-en-ergy and long-life lithium-sulfur ***,future outlooks are proposed on developing advanced catalytic host materials to improve battery performance.

关键词： lithium–sulfur batteries sulfur cathode catalytic host metal phosphides metal borides

Cognition-Based Interactive Phases and Strategies in Teaching Academic Reading

在线全文

学校读者我要写书评

暂无评论

Journal of Electronic Science and Technology 2017年第1期15卷 33-40页

作者： Zhao gao Shan gao qi Yang School of Foreign Languages University of Electronic Science and TechnologyChengdu 610054China

Academic English reading requires deeper cognitive involvement in addition to language proficiency and plays a vital role in moulding a critical mindset. However, cognitive progress is seldom targeted in classroom teaching. This study proposed a teaching method of three reading phases in terms of cognitive mechanism and communicative teaching *** university freshmen of non-English major participated in the study, who were taking the course of Academic English Reading in the 2nd semester. The data were collected from self-report Research Skills Assessment twice and semi-structured interview, and analyzed with paired sample t test and Pearson correlation. The results showed that 1） “critical thinking”, “organizing ideas”, and “finding information” were believed to improve significantly at the end of the course; 2） reading skill was associated with writing skill and the sense of “big picture” in self perception; 3） the cognition-based interactive reading instruction was acknowledged to be conducive to academic reading. It complements Academic English reading pedagogy by juxtaposing the need for both individual cognition and group interaction in classroom teaching.

关键词： Reading classroom skill proficiency interview thinking acknowledged instruction comprehension cognition

A lightweight cryptographic algorithm for the transmission of images from road environments in self-driving

在线全文

学校读者我要写书评

暂无评论

Cybersecurity 2018年第1期1卷 1-11页

作者： Runchen gao Shen Li Yuqi gao rui Guo School of Cyberspace Security Xi’an University of Posts&TelecommunicationsXi’an 710121China School of Telecommunication and Information Engineering Xi’an University of Posts&TelecommunicationsXi’an 710121China

With the large-scale application of 5G in industrial production,the Internet of Things has become an important technology for various industries to achieve efficiency improvement and digital transformation with the help of the mobile edge *** the modern industry,the user often stores data collected by IoT devices in the cloud,but the data at the edge of the network involves a large of the sensitive information,which increases the risk of privacy *** order to address these two challenges,we propose a security strategy in the edge *** security strategy combines the Feistel architecture and short comparable encryption based on sliding window(SCESW).Compared to existing security strategies,our proposed security strategy guarantees its security while significantly reducing the computational *** our GRC algorithm can be successfully deployed on a hardware platform.

关键词： 5G Internet of things(IoT) Mobile edge computing Feistel architecture SCESW GRC algorithm