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湖南大源洞金矿床地质特征及成因浅析

世界有色金属 2024年第5期 52-54页

作者：曾乐黄小强柳清琦湖南省地质灾害调查监测所湖南长沙410100

大源洞金矿地处扬子准地台江南地轴中段之湘东台拱区,属湖南省重要的黄金洞-万古金矿集区。矿区金矿脉赋存于新元古界冷家溪群坪原组地层中,受北西向构造控制,矿石类型主要为蚀变破碎板岩型,与金矿化关系密切的蚀变主要有硅化、毒砂化... 详细信息

大源洞金矿地处扬子准地台江南地轴中段之湘东台拱区,属湖南省重要的黄金洞-万古金矿集区。矿区金矿脉赋存于新元古界冷家溪群坪原组地层中,受北西向构造控制,矿石类型主要为蚀变破碎板岩型,与金矿化关系密切的蚀变主要有硅化、毒砂化、黄铁矿化。通过对矿区赋矿地层、含矿构造、矿脉特征、矿石特征以及深部矿化富集规律等分析研究,认为区内新元古界冷家溪群坪原组是金矿的主要矿源层与赋矿层位,区内的深大断裂为导岩导矿构造,次一级的近东西向断裂构造则起容矿构造作用,深部矿体具有变富变厚趋势。大源洞金矿经历了沉积成岩-区域变质-构造热液作用三个阶段,构造成矿作用是主要成矿作用,矿床成因类型为中(低)温热液型,并总结了地层标志、构造标志、岩浆岩标志、蚀变标志及化探标志等五类找矿标志,为区域金矿勘查提供地质依据。

关键词：大源洞金矿地质特征控矿因素矿床成因找矿标志

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Nootkatone Improves Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors by Repressing NF-κB/NLRP3-Mediated Neuroinflammation

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Chinese Journal of Integrative Medicine 2023年第1期29卷 37-43页

作者： ZHAO Xin-hua AN Na XIA Meng-huan LIU Wen-ping WANG qing-qi BAO Ji-zhang Basic Medical College Shanghai University of Traditional Chinese MedicineShanghai201203China Geriatrics Department Shanghai Mental Health CenterShanghai200030China Hematological Department Shanghai Municipal Hospital of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineShanghai200071China

Objective:To explore the effect of nootkatone(NKT) on chronic unpredictable mild stress(CUMS)-induced depressive-like behaviors and the mechanism underlying NKT improving the depressivelike behaviors.Methods:The CUMS-induced depression model was established in mice.Fifty mice were randomized into 5 groups(n=10) in accordance with a random number table:control group,CUMS group,CUMS+NKT(6 mg/kg) group,CUMS+NKT(12 mg/kg) group,and CUMS+ketamine group.From the 22th day,NKT(6 or 12 mg/kg) or ketamine(0.5 mg/kg) was given with intragastric administration every day for21 days.Behavioral tests including forced swimming test(FST),tail suspension test(TST),sucrose preference test(SPT) and open-field test(OFT) were carried out.The mRNA and protein expressions of interleukin(IL)-1β,IL-18,IL-6,and tumor necrosis factor(TNF)-α in hippocampus were assessed using quantitative realtime polymerase chain reaction(PCR),Western blot analysis,and enzyme linked immunosorbent assay.The nuclear factor-κB(NF-κB)/NOD-like receptor 3(NLRP3) inflammasome pathway was analyzed using Western blot and immunofluorescence analysis.Results:NKT treatment improved CUMS-induced depressivelike behaviors in mice(P<0.05 or P<0.01).NKT significantly decreased the mRNA and protein levels of IL-1β,IL-18,IL-6,and TNF-α in hippocampus of CUMS mice(P<0.05 or P<0.01).Furthermore,NKT repressed CUMS-induced activation of NF-κB signaling and NLRP3 inflammasome(P<0.01).More important,Nigericin,a NLRP3 activator,destroyed the effect of NKT on repressing neuroinflammation and improving depressive-like behaviors(P<0.05 or P<0.01).Conclusion:NKT ameliorates the depressive-like symptoms,in part by repressing NF-κB/NLRP3-mediated neuroinflammation.

关键词： nootkatone depressive disorder nuclear factor-κB NOD-like receptor 3 nuroinflammation

基于数字孪生技术的航海模拟器实践教学改革研究

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青岛远洋船员职业学院学报 2024年第2期45卷 62-65,69页

作者：徐进李博邱其清李凯刘乔广东海洋大学广东湛江524088

航海模拟器实践教学是航海类专业人才培养的重要环节。基于国内航海模拟器实践教学现状分析,以数字孪生技术为依托,探讨数字孪生技术在航海模拟器实践教学的应用与研发,满足新时代背景下航海模拟器实操训练的教学需求,提升我国海事类专... 详细信息

航海模拟器实践教学是航海类专业人才培养的重要环节。基于国内航海模拟器实践教学现状分析,以数字孪生技术为依托,探讨数字孪生技术在航海模拟器实践教学的应用与研发,满足新时代背景下航海模拟器实操训练的教学需求,提升我国海事类专业人才培养水平。

关键词：航海模拟器数字孪生实践教学

Skeleton Marching-based Parallel Vascular Geometry Reconstruction Using Implicit Functions

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国际自动化与计算杂志：英文版 2020年第1期17卷 30-43页

作者： Quan qi qing-De Li Yongqiang Cheng qing-qi Hong College of Information Science and Technology Shihezi UniversityShihezi 832003China Department of Computer Science and Technology University of HullHull HU67RXUK Software School Xiamen UniversityXiamen 361005China

Fast high-precision patient-specific vascular tissue and geometric structure reconstruction is an essential task for vascular tissue engineering and computer-aided minimally invasive vascular disease diagnosis and surgery.In this paper,we present an effective vascular geometry reconstruction technique by representing a highly complicated geometric structure of a vascular system as an implicit function.By implicit geometric modelling,we are able to reduce the complexity and level of difficulty of this geometric reconstruction task and turn it into a parallel process of reconstructing a set of simple short tubular-like vascular sections,thanks to the easy-blending nature of implicit geometries on combining implicitly modelled geometric forms.The basic idea behind our technique is to consider this extremely difficult task as a process of team exploration of an unknown environment like a cave.Based on this idea,we developed a parallel vascular modelling technique,called Skeleton Marching,for fast vascular geometric reconstruction.With the proposed technique,we first extract the vascular skeleton system from a given volumetric medical image.A set of sub-regions of a volumetric image containing a vascular segment is then identified by marching along the extracted skeleton tree.A localised segmentation method is then applied to each of these sub-image blocks to extract a point cloud from the surface of the short simple blood vessel segment contained in the image block.These small point clouds are then fitted with a set of implicit surfaces in a parallel manner.A high-precision geometric vascular tree is then reconstructed by blending together these simple tubular-shaped implicit surfaces using the shape-preserving blending operations.Experimental results show the time required for reconstructing a vascular system can be greatly reduced by the proposed parallel technique.

关键词： Vascular geometric reconstruction implicit modelling parallel computing high-performance high-accuracy

基于颗粒非连续变形法的路基桩网结构土拱效应

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科学技术与工程 2024年第7期24卷 2917-2926页

作者：刘启清李诚豪张凌之夏斌靳昆马建军黄林冲广东珠肇铁路有限责任公司广州510000 中山大学土木工程学院珠海519082

桩网路基由于其施工工期短和沉降变形小等优点在中国铁路和公路建设中得到了广泛的应用。为研究桩网路基中土拱效应的机理和影响因素,采用非连续变形分析方法(discontinuous deformation analysis, DDA),通过改变路基高度、桩间净距和... 详细信息

桩网路基由于其施工工期短和沉降变形小等优点在中国铁路和公路建设中得到了广泛的应用。为研究桩网路基中土拱效应的机理和影响因素,采用非连续变形分析方法(discontinuous deformation analysis, DDA),通过改变路基高度、桩间净距和土工格栅参数建立了九种不同模型。结果表明:数值结果与实验结果吻合良好,验证了非连续变形分析方法在模拟路基桩网结构土拱效应上的可行性;随着路基高度的增加,土拱产生的作用逐渐显著,等沉面高度稳定为0.8~0.85倍桩间净距;桩间净距对桩土应力比峰值时刻有明显影响,随着桩间净距的减小,桩顶接受来自路基荷载传递的压力增大,桩土应力比达到峰值的速度加快。桩间净距的减小会导致等沉面高度的下降;加入土工格栅后,桩网结构所产生的桩土应力比与未加入土工格栅的相比更大,说明土工格栅可有效提高路基强度。

关键词：非连续变形分析法路基高度桩间净距桩网路基土拱效应

Rheological Behaviors of Polymers with Nanoparticles Tethered at Each End

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Chinese Journal of Polymer Science 2024年第3期42卷 400-406,I0009页

作者： Song-qi Zhang Wen-qing Wang Jia-Ping Lin Li-Quan Wang Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China

The polymer with nanoparticles tethered at each end is a unique model for unraveling the effect of chain ends on the polymer dynamics. We investigated the rheological behavior of this kind of polymer by using nonequilibrium molecular dynamics simulation. The effect of polymer lengths and nanoparticle radii on the complex moduli and viscosity was examined. The dependence of complex moduli on the frequency becomes less pronounced as the polymer is short or the nanoparticle is large. The shear thinning behavior was revealed for these systems, and the scaling exponent of complex viscosity with respect to the frequency was found to change from-1/2 to-3/4 as the polymer shortens or the nanoparticle enlarges. The rheological behavior was further explained by analyzing the mean square distance of nanoparticles. The simulation results were compared with the existing experimental finding, showing an agreement. The work provides information for understanding the chain end effect on polymer rheology.

关键词： Polymer rheology Modulus Viscosity Molecular dynamics

Significantly Enhanced Energy Storage Performances of PEI-based Composites Utilizing Surface Functionalized ZrO_(2) Nanoparticles for High-Temperature Application

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Chinese Journal of Polymer Science 2024年第3期42卷 322-332,I0006页

作者： qing-qing Liu qiu-Hao Lin Xiao-Dong qi Nan Zhang Ting Huang Jing-Hui Yang Yong Wang School of Chemistry Southwest Jiaotong UniversityChengdu 610031China Key Laboratory of Advanced Technologies of Materials Ministry of Education of ChinaSouthwest Jiaotong UniversityChengdu 610031China

Polymer dielectrics with a high energy density and an available energy storage capacity have been playing an important role in advanced electronics and power systems. Nevertheless, the use of polymer dielectrics in harsh environments is limited by their low energy density at high temperatures. Herein, zirconium dioxide(ZrO_(2)) nanoparticles were decorated with amino group utilizing 4,4-methylenebis(phenyl isocyanate)(AMEO) and successfully incorporated into polyetherimide(PEI) matrix. The dielectric properties, breakdown strength, and energy storage performances of PEI/ZrO_(2)-AMEO nanocomposites were investigated from 25 ℃ to 150 ℃. It is found that the combination of moderate bandgap ZrO_(2) with modest dielectric constant and polar groups at interface with deep trap can offer an available strategy to simultaneously increase the dielectric constant and breakdown strength of polymer dielectrics. As a result, the composites containing ZrO_(2)-AMEO exhibit excellent energy storage performance at elevated temperatures. Specially, the PEI-based composites with 3 vol% ZrO_(2)-AMEO display a maximum discharged energy density(U_(d)) of 3.1 J/cm^(3) at 150 ℃, presenting 90% higher than that of neat PEI. This study may help to better develop the polymer-based dielectric composite applied at elevated temperatures.

关键词： Polyetherimide High temperature dielectric ZrO_(2) Interface

同种异体富血小板血浆治疗肠造口周围皮肤损伤的探讨--附2例报道

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中国输血杂志 2024年第2期37卷 209-213页

作者：姚红林齐清王淑君沈硕栾建凤叶向红东部战区总医院全军普通外科研究所江苏南京210002 东部战区总医院输血医学科江苏南京210002

目的探讨同种异体富血小板血浆(platelet rich plasma,PRP)应用于肠造口周围皮肤损伤治疗的可行性。方法分析2例应用PRP治疗肠造口周围皮肤损伤患者的治疗及护理过程,并对使用的PRP进行血小板、细菌检测和5种生长因子检测。结合治疗难... 详细信息

目的探讨同种异体富血小板血浆(platelet rich plasma,PRP)应用于肠造口周围皮肤损伤治疗的可行性。方法分析2例应用PRP治疗肠造口周围皮肤损伤患者的治疗及护理过程,并对使用的PRP进行血小板、细菌检测和5种生长因子检测。结合治疗难点与文献内容复习,探讨肠内营养支持治疗的同时予以同种异体PRP治疗肠造口周围损伤的临床治疗效果。结果患者在清洁肠造口周围皮肤后,予以每日1次PRP治疗5 d后调整为隔日1次,分别于15 d和18 d达到治愈。结论异体PRP是1种安全、有效的促进肠造口周围皮肤损伤的治疗方法,为临床治疗提供新的思路。

关键词：富血小板血浆肠造口造口周围皮肤损伤

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固体环氧树脂固化特性研究

广州化工 2024年第6期52卷 88-90,103页

作者：田井速李娟罗恒艾吉祥秦数张启青贵州省材料技术创新基地贵州贵阳550014 贵州省材料产业技术研究院贵州贵阳550014 贵州至当科技有限公司贵州贵阳550000

固体环氧树脂是一种广泛应用于各个领域的聚合物材料。本研究采用Gelprof518树脂反应行为分析仪研究了固体环氧E20树脂在不同固化剂添加量、不同种类固化剂及其不同固化温度条件下的固化特性,探究固化温度、固化剂添加量及固化剂种类对... 详细信息

固体环氧树脂是一种广泛应用于各个领域的聚合物材料。本研究采用Gelprof518树脂反应行为分析仪研究了固体环氧E20树脂在不同固化剂添加量、不同种类固化剂及其不同固化温度条件下的固化特性,探究固化温度、固化剂添加量及固化剂种类对固化反应速率的影响。结果表明:固化剂类型、温度和时间对固化反应速率和反应程度有显著影响。不同的固化条件下,固化反应的速率和程度存在差异,随着固化温度的升高,固化时间缩短;随着固化剂添加量的增加固化时间也相应的缩短;四氢邻苯二甲酸酐反应活性较邻苯二甲酸酐高,表现为在相同固化剂添加量下反应时间较短。在实际应用中需要根据具体应用需求进行选择。

关键词：固体环氧树脂固化特性固化温度固化剂添加量固化剂种类