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Deep learning for electrolysis process anode effect prediction based on long short-term memory network and stacked denoising autoencoder

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Rare Metals 2024年第12期43卷 6730-6741页

作者： gang yin Yi-Hui Li Fei-Ya Yan Peng-Cheng Quan Min Wang Wen-qi Cao heng-Quan Xu Jian Lu Wen he School of Resource and Safety Engineering and State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing University Guiyang Aluminium Magnesium Design and Research Institute Co. Ltd. Aba Aluminium Factory Chongqing qineng Electric Aluminium Co. Ltd. Bomei qimingxing Aluminium Co. Ltd.

The anode effect is a common failure in the aluminium electrolysis *** the anode effect cannot be accurately predicted,it will cause increased energy consumption,harmful gas generation and even equipment damage in the aluminium *** this paper,an anode effect prediction framework using multi-model merging based on deep learning technology is *** models are used to process aluminium electrolysis cell condition parameters with high dimensions and different characteristics,and hidden key fault information is deeply mined.A stacked denoising autoencoder is utilized to denoise and extract features from a large number of longperiod parameter data.A long short-term memory network is implemented to identify the intrinsic links between the realtime voltage and current time series and the anode *** setting the model time step,the anode effect can be predicted precisely in advance,and the proposed method has good robustness and ***,the traditional Adam algorithm is improved,which enhances the performance and convergence speed of the *** experimental results show that the classification accuracy and F1score of the model are 97.14% and 0.9579%,*** prediction time can reach 15 min.

关键词： Aluminium electrolysis Anode effect prediction Deep learning Improved Adam algorithm Merging model

Androgen signaling inhibits de novo lipogenesis to alleviate lipid deposition in zebrafish

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Zoological Research 2024年第2期45卷 355-366页

作者： Jing-Yi Jia Guang-Hui Chen Ting-Ting Shu qi-Yong Lou Xia Jin Jiang-Yan he Wu-Han Xiao gang Zhai Zhan yin College of Fisheries Huazhong Agriculture UniversityWuhanHubei 430070China State Key Laboratory of Freshwater Ecology and Biotechnology Institute of HydrobiologyChinese Academy of SciencesWuhanHubei 430072China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China Hubei Key Laboratory of Three Gorges Project for Conservation of Fishes Chinese Sturgeon Research InstituteChina Three Gorges CorporationYichangHubei 443100China Hubei Hongshan Laboratory Huazhong Agriculture UniversityWuhanHubei 430070China Innovative Academy of Seed Design Chinese Academy of SciencesBeijing 100049China

Testosterone is closely associated with lipid metabolism and known to affect body fat composition and muscle mass in ***,the mechanisms by which testosterone acts on lipid metabolism are not yet fully understood,especially in *** this study,cyp17a1-/-zebrafish(Danio rerio)exhibited excessive visceral adipose tissue(VAT),lipid content,and up-regulated expression and activity of hepatic de novo lipogenesis(DNL)*** assay for transposase accessible chromatinwithsequencing(ATAC-seq)results demonstrated that chromatin accessibility of DNL genes was increased in cyp17a1-/-fish compared to cyp17a1+/+male fish,including stearoyl-CoA desaturase(scd)and fatty acid synthase(fasn).Androgen response element(ARE)motifs in the androgen signaling pathway were significantly enriched in cyp17a1+/+male fish but not in cyp17a1-/-*** androgen receptor(ar)-/-and wildtype(WT)zebrafish administered with Ar antagonist flutamide displayed excessive visceral adipose tissue,lipid content,and up-regulated expression and activity of hepatic de novo lipogenesis *** Ar agonist BMS-564929 reduced the content of VAT and lipid content,and down-regulated acetyl-CoA carboxylase a(acaca),fasn,and scd ***,the rescue effect of testosterone on cyp17a1-/-fish in terms of phenotypes was abolished when ar was additionally ***,these findings reveal that testosterone inhibits lipid deposition by down-regulating DNL genes via Ar in zebrafish,thus expanding our understanding of the relationship between testosterone and lipid metabolism in teleosts.

关键词： Cyp17a1 Testosterone Androgen receptor De novo lipogenesis Fatty acid synthesis

Prognostic factors in non-malignant and non-cirrhotic patients with portal cavernoma: An 8-year retrospective single-center study

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World Journal of Gastroenterology 2013年第42期19卷 7447-7454页

作者： Xing-Shun qi Ming Bai Chuang-Ye he Zhan-Xin yin Wen-gang Guo Jing Niu Fei-Fei Wu Guo-Hong Han Department of Liver Diseases and Digestive Interventional Radiology Xijing Hospital of Digestive DiseasesFourth Military Medical University

AIM:To evaluate the outcome of non-malignant and non-cirrhotic patients with portal cavernoma and to determine the predictors for ***:Between July 2002 and June 2010,we retrospectively enrolled all consecutive patients admitted to our department with a diagnosis of portal cavernoma without abdominal malignancy or liver *** primary endpoint of this observational study was death and cause of *** predictors of survival were identified using the Cox regression ***:A total of 64 patients were enrolled in the *** a mean follow-up period of 18±2.41mo,7 patients *** of death were pulmonary embolism(n=1),acute leukemia(n=1),massive esophageal variceal hemorrhage(n=1),progressive liver failure(n=2),severe systemic infection secondary to multiple liver abscesses(n=1)and accident(n=1).The cumulative 6-,12-and 36-mo survival rates were 94.9%,86%and 86%,*** Cox regression analysis demonstrated that the presence of ascites(HR=10.729,95%CI:1.209-95.183,P=0.033)and elevated white blood cell count(HR=1.072,95%CI:1.014-1.133,P=0.015)were independent prognostic factors of non-malignant and non-cirrhotic patients with portal *** cumulative 6-,12-and 36-mo survival rates were significantly different between patients with and without ascites(90%,61.5%and 61.5%vs 97.3%,97.3%and 97.3%,respectively,P=0.0008).CONCLUSION:The presence of ascites and elevated white blood cell count were significantly associated with poor prognosis in non-malignant and non-cirrhotic patients with portal cavernoma.

关键词： Extrahepatic portal vein obstruction Portal cavernoma Survival Prognostic factors Ascites

Shunting branch of portal vein and stent position predict survival after transjugular intrahepatic portosystemic shunt

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World Journal of Gastroenterology 2014年第3期20卷 774-785页

作者： Ming Bai Chuang-Ye he Xing-Shun qi Zhan-Xin yin Jian-Hong Wang Wen-gang Guo Jing Niu Jie-Lai Xia Zhuo-Li Zhang Andrew C Larson Kai-Chun Wu Dai-Ming Fan Guo-Hong Han Department of Liver Disease and Department of Digestive Interventional Radiology Xijing Hospital of Digestive DiseasesFourth Military Medical University Department of Ultrasound Xijing Hospital of Digestive Diseases Department of Medical Statistics Fourth Military Medical University Department of Radiology Northwestern University Department of Radiology Xijing Hospital Xijing Hospital of Digestive Diseases

AIM: To evaluate the effect of the shunting branch of the portal vein (PV) (left or right) and the initial stent position (optimal or suboptimal) of a transjugular intrahepatic portosystemic shunt (TIPS).

关键词： Transjugular intrahepatic portosystemic shunt Cirrhosis Variceal bleeding Portal vein Stent position

Diversity and independent evolutionary profiling of rodent-borne viruses in Hainan,a tropical island of China

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Virologica Sinica 2023年第5期38卷 651-662页

作者： Youyou Li Chuanning Tang Yun Zhang Zihan Li Gaoyu Wang Ruoyan Peng Yi Huang Xiaoyuan Hu henan Xin Boxuan Feng Xuefang Cao Yongpeng he Tonglei Guo Yijun he Haoxiang Su Xiuji Cui Lina Niu Zhiqiang Wu Jian Yang Fan Yang gang Lu Lei Gao qi Jin Meifang Xiao Feifei yin Jiang Du NHC Key Laboratory of Systems Biology of Pathogens Institute of Pathogen BiologyChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100005China Department of Clinical Laboratory Center for Laboratory MedicineHainan Women and Children's Medical CenterHaikou571199China Key Laboratory of Tropical Translational Medicine of Ministry of Education Hainan Medical UniversityHaikou571199China Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases Hainan Medical UniversityHaikou571199China Department of Pathogen Biology Hainan Medical UniversityHaikou571199China

The risk of emerging infectious diseases(EID)is increasing *** than 60%of EIDs worldwide are caused by animal-borne *** study aimed to characterize the virome,analyze the phylogenetic evolution,and determine the diversity of rodent-borne viruses in Hainan Province,*** collected 682 anal and throat samples from rodents,combined them into 28 pools according to their species and location,and processed them for next-generation sequencing and bioinformatics *** diverse viral contigs closely related to mammals were assigned to 22 viral *** clues of the important rodent-borne viruses were further identified by polymerase chain reaction for phylogenetic analysis and annotation of genetic characteristics such as arenavirus,coronavirus,astrovirus,pestivirus,parvovirus,and *** identified pestivirus and bocavirus in Leopoldoms edwardsi from Huangjinjiaoling,and bocavirus in Rattus andamanensis from the national nature reserves of Bangxi with low amino acid identity to known pathogens are proposed as the novel species,and their rodent hosts have not been previously reported to carry these *** results expand our knowledge of viral classification and host range and suggest that there are highly diverse,undiscovered viruses that have evolved independently in their unique wildlife hosts in inaccessible areas.

关键词： Rodents Virome Phylogenetic analysis Novel viruses Wildlife

浅谈大学英语通识教育和专门用途英语教学的关系——兼论新一轮大学英语教学改革发展方向

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外语电化教学 2011年第1期 9-14页

作者：殷和素严启刚四川外语学院大学外语教学部

本文通过分析北大、浙大和同济大学高级阶段大学英语教学现状，认为大学英语通识教育和专门用途英语可以同步发展，是相辅相成的关系。研究认为大学生英语学习应该分为两个层次，三个阶段。“两个层次”即基础英语层次和专门用途英语层... 详细信息

本文通过分析北大、浙大和同济大学高级阶段大学英语教学现状，认为大学英语通识教育和专门用途英语可以同步发展，是相辅相成的关系。研究认为大学生英语学习应该分为两个层次，三个阶段。“两个层次”即基础英语层次和专门用途英语层次（专业化阶段）。基础英语层次包含两个阶段：核心英语学习阶段和英语通识教育阶段。整个大学英语学习分为三个阶段：核心英语学习阶段、大学英语通识教育阶段和专门用途英语阶段。根据北大、浙大和同济大学的教学实践，文章进一步指出大学英语通识教育应该由大学英语老师来承担，而专门用途英语教学则主要应该由所在专业的专业老师来承担。

关键词：英语通识教育专门用途英语大学英语教学改革

Inflammation inhibitory effects of sirolimus and paclitaxel-eluting stents on interleukin-1β-induced coronary artery in-stent restenosis in pigs

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Chinese Medical Journal 2010年第17期123卷 2405-2409页

作者： ZHOU Xu-chen HUANG Rong-chong ZHANG Bo yin Da LIANG Bin WANG Shao-peng GUAN qi-gang SUN Xi-zhuo MIAO Zhi-lin he Xue-zhi HAN Feng-tong CheNG ying ZHANG Li ZENG Ding-yin Department of Cardiology First Affiliated Hospital of Dalian Medical University Dalian Liaoning 116011 China Department of Cardiology First Affiliated Hospital of China Medical University Shenyang Liaoning 110001 China Department of Cardiology Dalian Central Hospital Dalian Liaoning 116000 China

Background Coronary artery in-stent restenosis （ISR） and late stent thrombosis remain as important complications of stenting. The inflammation reactions to sirolimus and paclitaxel-eluting stents were investigated in a swine stenosis model induced by interleukin （IL）-1β.Methods Mini pigs （n=12; 2-3 months old and weighing 25-30 kg） were subjected to thoracotomy. Segments （10 mm）of the mid left anterior descending coronary artery and left circumflex coronary artery were exposed and aseptically wrapped with a cotton mesh soaked with IL-1β （5 μg）. After 2 weeks, the animals were anesthetized and quantitative coronary arteriography （QCA） was performed. The stenosis sites were randomized into three groups for stent insertion： a sirolimus-eluting stent （SES） group （FirebirdTM, n=7）, a paclitaxel-eluting stent （PES） group （TAXUSTM, n=9）, and a bare-metal stent （BMS） group （yinYITM, Dalian yinyi Biomaterials Development Co., Ltd, China, n=8）. The three different stents were randomly implanted into stenosis segments. Expression of monocyte chemoattractant protein-1 （MCP-1）, tumor necrosis factor-alpha （TNF-α）, P-selectin and vascular cell adhesion molecule-1 （VCAM-1） was determined by reverse transcription-coupled polymerase chain reaction （RT-PCR）.Results QCA showed severe stenosis in IL-1β treated segments. The SES and PES groups showed lower 1-month angiographic late lumen loss （LLL） within the stent and the lesion compared with BMS （P 〈0.05） by follow-up QCA. The SES showed lower LLL than that of PES in reducing 1-month inflammation lesions in pigs by follow-up QCA （（0.15±0.06）mm vs. （0.33±0.01） mm, P 〈0.0001）. The neointimal hyperplasia areas in SES and PES showed lower than those of BMS （SES （11.6±1.7） mm2, PES （27.2±1.6） mm2 vs. BMS （76.2±1.3） mm2, P 〈0.0001）. The mRNA expression of MCP-1 by RT-PCR in SES and PES showed lower than that of BMS at 30 days after stenting （SES 0.20±0.03, PES 0.48±0.49 *** 0.58±0.07, P 〈0.05）. Levels of VCAM-1 in SES were significantly

关键词： interleukin-1β sirolimus paclitaxel drug-eluting stent inflammation in-stent restenosis

Lipid signal in evaluation of intracranial meningiomas

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Chinese Medical Journal 2008年第23期121卷 2415-2419页

作者： qi Zhi-gang LI Yu-xin WANG Yan GENG Dao-yin LI Kun-cheng SheN Tian-zhen CheN Xin-rong Department of Radiology Xuanwu Hospital Capital Medical University Beijing 100053 China Department of Radiology Huashan Hospital Fudan University Shanghai 200040 China Department of Pathology Huashan Hospital Fudan University Shanghai 200040 China

Background Using magnetic resonance imaging, diagnosis of malignant meningioma from benign meningioma with atypical features is uncertain. We evaluated the value of lipid signal in differentiating intracranial meningiomas. Methods ^1H-magnetic resonance spectroscopy （MRS） using a point resolved spectroscopy （TR/TE 1000/144 ms） sequences were performed on 34 patients on a 3.0 T scanner. Lipid peak located at 1.3 ppm was evaluated. MRS data from these tumours were compared with histopathological findings （including hematoxylin and eosin staining and KP-1 staining）. Results Twenty-nine meningiomas were histologically benign （eleven meningothelial, thirteen fibrous, four transitional and one microcystic）, three were atypical, and two were anaplastic. Lipid signal was detected in ten cases： two anaplastic three atypical, two fibrous and three rneningothelial meningiomas. All voxels with lipid peak in the spectrum from the tumour were evaluated. With creatinine peak in the normal white matter chosen as internal standard, lipid/creatinine ratios of anaplastic, atypical and benign meningiomas were 0.844±0.027 （range from 0.725 to 0.994）, 0.465±0.023 （range from 0.239 to 0.724）, and 0.373±0.016 （range from 0.172 to 0.571） respectively. Highly significant differences were noted between anaplastic and the other two subtypes. Patchy necrosis was observed in anaplastic meningioma, while focal necrosis was noted in atypical meningioma with he stain. However, no necrosis was found in benign group. KP-1 stain demonstrated histocytes containing lipids in the necrotic region of anaplastic and atypical meningioma. Conclusion The lipid signal at 1.3 ppm is a useful marker in evaluating the malignancy of intracranial meningiomas, especially in the differential diagnosis of anaplastic meningioma.

关键词： meningioma magnetic resonance spectroscopy lipid diagnosis

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湖北恩施桢楠林群落组成与结构

林业科学研究 2013年第1期26卷 21-28页

作者：王琦李因刚柳新红吴代坤刘芳齐何云核浙江农林大学浙江临安311300 浙江省林业科学研究院浙江杭州310023 恩施自治州林业科学研究所湖北恩施445000

利用群落生态学方法对恩施桢楠林群落组成与结构进行调查分析。结果表明:恩施桢楠林群落物种丰富,共有维管束植物97科229属332种,含有单种植物的属较多,优势科主要有蔷薇科、禾本科、豆科、百合科。乔木层(DBH≥2.5 cm)优势树种明显,从... 详细信息

利用群落生态学方法对恩施桢楠林群落组成与结构进行调查分析。结果表明:恩施桢楠林群落物种丰富,共有维管束植物97科229属332种,含有单种植物的属较多,优势科主要有蔷薇科、禾本科、豆科、百合科。乔木层(DBH≥2.5 cm)优势树种明显,从个体数、平均胸径、胸高断面积和重要值分析来看,桢楠(Phoebe zhennan)在群落中占绝对优势地位。群落区系类型以热带成分较多,93属是热带分布,90属是温带分布。群落成层现象明显,可划分为乔木层、灌木层和草本层。样地内所有木本植物的径级分布呈峰型,表明群落正常生长;从主要树种的径级结构来看,桢楠、枫香(Liquidambar formosana)和杉木(Cunninghamia lanceolata)种群均为增长型或稳定型种群,群落更新良好,正渐趋稳定。灌木层植物种类最丰富,草本层次之,物种多样性大小顺序依次为灌木层>草本层>乔木层。

关键词：桢楠林物种组成径级结构物种多样性湖北恩施