检索结果-南通市图书馆

Chinese Science Bulletin 2007年第12期52卷 1623-1628页

作者： XU XiaoPing YAO YingMing ZHANG Yong SHEN qi Key Laboratory of Organic Synthesis of Jiangsu Province Department of Chemistry and Chemical Engineering Dushu Lake Campus Suzhou University Suzhou 215123 China State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China

Lanthanide methoxides supported by carbon-bridged bis(phenolate) ligands 2,2′-methylene-bis(6-tert- butyl-4-methylphenoxo) (MBMP2-) [(MBMP)Ln( μ-OMe)(THF)2]2 (Ln = Nd (1), Yb (2)) were synthesized in high yields by the protolysis reaction using (C5H5)3Ln(THF) as starting materials, and complex 1 was structurally characterized. The coordination geometry around the center metal can be best described as a distorted octahedron. Complexes 1 and 2 were shown to be efficient initiators for the ring-opening polymerization of 2,2-dimethyltrimethylene carbonate (DTC) and L-lactide. The mechanism of DTC polymerization was explored by the end group analysis of the oligomer.

关键词：稀土元素甲醇盐二苯酚盐配体丙交酯碳酸盐聚合物

Effects of Huatan Jiangzhuo decoction on diet-induced hyperlipidemia and gene expressions in rats

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2021年第2期19卷 100-111页

作者： REN qi LIU Xiao-qi ZHOU Xiao-Wen ZHOU Xuan FANG Ge WANG Bin WANG Yan-Ping PENG Dan-Hong LI Xian-Tao School of Basic Medical Science Guangzhou University of Chinese MedicineGuangzhou 510006China

Huatan Jiangzhuo decoction(HJD)is a combination of six traditional Chinese medicines that were used for lipid metabolism-related disorders,but its efficacy and underlying mechanisms have not been explored by modern research *** study aimed to investigate the therapeutic role of HJD in determining the transcriptome *** model was established by feeding Sprague–Dawley rats with high-fat *** expressed genes(DEGs)were detected by high-through transcriptome sequencing,followed by gene ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)*** total cholesterol(TC)and triglyceride(TG)levels in hyperlipidemia model rats were significantly increased,whereas high-density lipoprotein(HDL)concentration decreased when compared to normal rats,and HJD significantly downregulated TC concentrations and liver coefficient in the hyperlipidemia *** staining showed that HDJ greatly recovered the lipid accumulation in rat hepatic stellate cells and aortic arch vascular wall thickness of hyperlipidemia *** thousand nine hundred and thirty-six DEGs were identified in the HJD-treated hyperlipidemia rats,which were associated with various biological processes and signaling pathways such as peroxisome proliferator-activated receptors,AMP-activated Protein Kinase,and insulin signaling *** reverse transcription–polymerase chain reaction further confirmed the downregulated expression of cholesterol 7-α-hydroxylase(CYP7A1),liver orphan receptor(LXRα),peroxisome proliferator-activated receptor gamma(PPARγ),and Sterol Response Element-Binding Protein 1c(SREBP1c)genes in hyperlipidemia rats treated with *** data first elucidated the gene expression profile of high-fat diet-induced hyperlipidemia in rats after HJD treatment,and lipid metabolism-related genes(CYP7A1,LXRα,PPARγ,and SREBP1c)may be potentially biomarkers for HJD-alleviated hyperlipidemia.

关键词： Hyperlipidemia Huatan Jiangzhuo decoction High-fat diet Fatty liver Next-generation sequencing

An Ant Colony Algorithm Based on Cross-Layer Design for Routing and Wavelength Assignment in Optical Satellite Networks

在线全文

学校读者我要写书评

暂无评论

China Communications 2017年第8期14卷 63-75页

作者： Guoli Wen qi Zhang Houtian Wang qinghua Tian Ying Tao School of Electronic Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China Beijing Key Laboratory of Space-ground Interconnection and Convergence Beijing University of Posts and TelecommunicationsBeijing 100876China China Academy of Space Technology Beijing 100094China

This paper introduces an ant colony routing and wavelength assignment algorithm based on cross-layer design(CL-ACRWA),which can overcome the adverse effects of Doppler wavelength shift on data transmission in optical satellite networks. Firstly, a cross-layer optimization model is built, which considers the Doppler wavelength shift, the transmission delay as well as wavelength-continuity constraint. Then an ant colony algorithm is utilized to solve the cross-layer optimization model, resulting in finding an optimal light path satisfying the above constraints for every connection request. The performance of CL-ACRWA is measured by the communication success probability, the convergence property and the transmission delay. Simulation results show that CL-ACRWA performs well in communication success probability and has good global search ability as well as fast convergence speed. Meanwhile, the transmission delay can meet the basic requirement of real-time transmission of business.

关键词： optical satellite network routing and wavelength assignment ant colony optimization cross-layer design Doppler wavelength shift

The development of metal hydrides using as concentrating solar thermal storage materials

在线全文

学校读者我要写书评

暂无评论

Frontiers of Materials Science 2015年第4期9卷 317-331页

作者： Xuanhui QU Yang LI Ping LI qi WAN Fuqiang ZHai State Key Laboratory for Advanced Metals and Materials Institute for Advanced Materials and Technology University of Science and Technology Beijing Beijing 100083 China Energy Material & Technology Research Institute General Researct Institute for Nonferrous Metals Beijing 100088 China Departament Fisica Aplicada EETAC Universitat Politecnica de Catalunya-BarcelonaTech 08860 Castelldefels Spain

Metal hydrides high temperature thermal heat storage technique has great promising future prospects in solar power generation, industrial waste heat utilization and peak load regulating of power system. This article introduces basic principle of metal hydrides for thermal storage, and summarizes developments in advanced metal hydrides high-temperature thermal storage materials, numerical simulation and thermodynamic calculation in thermal storage systems, and metal hydrides thermal storage prototypes. Finally, the future metal hydrides high temperature thermal heat storage technique is been looked ahead.

关键词： metal hydride concentrating solar power heat storage

Infrared radiation method for measuring ice segregation temperature of artificially frozen soils

在线全文

学校读者我要写书评

暂无评论

International Journal of Mining Science and Technology 2012年第1期22卷 35-40页

作者： Zhou Guoqing Zhang qi Xu Zhiwei Zhou Yang State Key Laboratory of Geomechanics and Deep Underground Engineering China University of Mining&TechnologyXuzhou 221008China Department of Geotechnical Engineering Tongji UniversityShanghai 200092China

In order to study the evolution of the freezing fringe and final lenses of frost susceptible soils and advance the understanding of frost heave and mechanism of frost heave control, we used an open one-dimensional frost heave test system of infrared radiation technology, instead of a traditional thermistor method. Temperatures of the freezing fringe and segregated ice were measured in a non-contact mode. The results show that accurate and precise temperatures of ice segregation can be obtained by infrared thermal imaging systems. A self-developed inversion program inverted the temperature field of frozen soils. Based on our analysis of temperature variation in segregated ice and our study of the relationship between temperature and rate of ice segregation in cooling and warming processes during intermittent freezing, the mechanism of decreasing frost heave of frozen soils by controlling the growth of final lenses with an intermittent freezing mode, can be explained properly.

关键词： One-dimensional freezing Final lens Ice segregation temperature measurement Infrared radiation method

B lymphoma Moloney murine leukemia virus insertion region 1: An oncogenic mediator in prostate cancer

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2019年第3期21卷 224-232页

作者： qipeng Liu qiaqia Li Sen Zhu Yang Yi qi Cao Center for Inflammation and Epigenetics Houston Methodist Research Institute Houston TX 77030 USA Xiangya School of Medicine Central South University Changsha 410008 China Key Laboratory for Stem Cells and Tissue Engineering Ministry of Education Sun Yat-Sen University Guangzhou 510080 China Department of Histology and Embryology Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China Houston Methodist Cancer Center Houston Methodist Research Institute Houston TX 77030 USA Department of Microbiology and Immunology Weill Cornell Medicine Cornell University New York NY 10065 USA

B lymphoma Moloney murine leukemia virus insertion region 1 (BMI1), a core member of polycomb repressive complex 1 (PRC1), has been intensely investigated in the field of cancer epigenetics for decades. Widely known as a critical regulator in cellular physiology, BMI1 is essential in self-renewal and differentiation in different lineages of stem cells. BMI1 also plays a significant role in cancer etiology for its involvement in pathological progress such as epithelial–mesenchymal transition (EMT) and cancer stem cell maintenance, propagation, and differentiation. Importantly, overexpression of BMI1 is predictive for drug resistance, tumor recurrence, and eventual therapy failure of various cancer subtypes, which renders the pharmacological targeting at BMI1 as a novel and promising therapeutic approach. The study on prostate cancer, a prevalent hormone-related cancer among men, has promoted enormous research advancements in cancer genetics and epigenetics. This review summarizes the role of BMI1 as an oncogenic and epigenetic regulator in tumor initiation, progression, and relapse of prostate cancer.

关键词： B lymphoma Moloney murine leukemia virus insertion region 1 oncogene polycomb repressive complex 1 prostate cancer

What took you so long?Peptide-receptor kinase signaling mediates reproductive isolation in plants

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science Bulletin 2019年第19期64卷 1390-1392页

作者： Yu-Jie Li Jia-qi Pei Wei-Hua Tang National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologyChinese Academy ofSciencesShanghai200032China University of the Chinese Academy of Sciences Beijing100049China

The peptide-receptor kinase-based intercellular signaling becomes an important molecular base for various aspects of plant life activities[1],particularly exemplified in the extensive molecular interactions in the journey of pollen tube growth in pistil of flowering plants[2].Researches in the past two decades demonstrated that peptide-receptor kinase signaling complexes mediat epollen tube promotion,guidance and reception,as well as selfincompatibility and gamete fusion.A recent exciting discovery published on Science by Zhong et *** the biological functions of peptide-receptor kinase signaling to facilitating formation of a new plant species[3].

关键词： so long Peptide-receptor in plants

Comparative Proteomic Analysis of Wheat (Triticum aestivum L.) Hybrid Necrosis

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2013年第3期12卷 387-397页

作者： JIANG qi-yan HU Zheng PAN Xing-lai ZHANG Hui National Key Facilities for Crop Genetic Resources and Improvement Institute of Crop Sciences Chinese Academy of Agricultural Sciences Food Crop Science Department Cotton Research Institute Shanxi Academy of Agriculture Sciences

Hybrid necrosis is the gradual premature death of leaves or plants in certain Fj hybrids of wheat （Triticum aestivum L.）. Comparison of protein expression in necrotic and normal wheat leaves showed that the abundance of 33 proteins was changed significantly, and 24 of these proteins were identified. These proteins were involved in plant growth and development, antioxidation, photosynthesis and carbon assimilation, amino acid and protein biosynthesis, cytological signal transduction, DNA and RNA modification, protein transport, folding and assembly according to their functions. The down-regulation of uroporphyrinogen decarboxylase and the up-regulation of lipoxygenases in necrotic leaves may be related to the oxidative stress in the necrotic cells. The heat shock proteins may play the cytoprotective role. The differential expression of photosynthesis and carbon assimilation related proteins indicated chlorophyll biosynthesis and chloroplast development were inhibited and might finally cause the gradual chlorosis and cell death in necrotic leaves. The results of this study give a comprehensive picture of the post-transcriptional response to necrosis in hybrid wheat leaves and serve as a platform for further characterization of gene function and regulation in wheat hybrid necrosis.

关键词： hybrid necrosis proteomic wheat differentially expressed protein

A Model for Precipitation Kinetics in Vanadium Microalloyed Steel

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2010年第2期17卷 36-42页

作者： FANG Fang YONG qi-long YANG Cai-fu SU Hang Structure Material Institute Central Iron and Steel Research Institute Beijing 100081 China

Small dispersoid particles inhibit recrystallization which is critical in controlling the grain structure of many high strength low alloy steels. A general kinetic model has been developed to predict precipitation of V（C, N） in vanadium microalloyed steels with a series of carbon and nitrogen contents. The solubility product and driving force of carbonitrides precipitated in austenite as well as the interracial energy and other parameters can be evaluated to predict Nucleation rates-Temperature （NrT） and Precipitation-Time-Temperature （PTT） diagram. By using stress relaxation tests and fitting with Avrami equation, it is possible to draw PTT diagrams. The predictions of the model coincide with results of experimental investigation on V（C, N） precipitation in austenite. The nose temperature is around 850 ℃ obtained by experiment which is different from the prediction of the model and the difference is 30 ℃, and nitrogen has more effect on the shape of ＂C＂ curve of PTT diagram than carbon that makes ＂C＂ curve move leftward significantly.

关键词： kinetic calculation model PTT curve stress relaxation nitrogen

Phase Evolution and Oxidation Resistance of YSZ/(Ni,Al) Composite Coatings in CH_4 Atmosphere

在线全文

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2018年第2期33卷 305-311页

作者：谭世磊 wang lili qi xiaoxiao song shanguang 王伟 School of Materials Engineering Shanghai University of Engineering Science Shanghai 201620 China

YSZ/（Ni, Al） composite coatings with different Ni：Al mole ratios were deposited on superalloy Inconel 600 by electrophoretic deposition（EPD） technique, followed by sintering in CH_4 atmosphere at 1 100 ℃for 2 h and isothermally oxidation at 1000 ℃ for 50 h. After sintering at 1100 ℃ for 2 h in CH_4 atmosphere, besides ZrC and t-ZrO_2 phases, the phase constitutes of Ni：Al mole ratios with 1：3, 1：2, and 1：1 were（Zr, Al）C, AlNi_3 and Ni phases, respectively. A remarkable difference in the oxidation behaviors of YSZ/（Ni, Al） composite coatings with different Ni：Al mole ratios was observed. For YSZ（Ni：Al=1：3） coated sample, oxidation at 1000 ℃ causes decomposition of the（Zr,Al）C solid solution to metallic Al, and then most of the Al is oxidized to Al_2O_3. For the YSZ（Ni：Al=1：2） coated sample, oxidation at 1000 ℃ mainly causes decomposition of the AlNi_3 phase. For YSZ（Ni：Al=1：1） coated sample, after oxidation at 1000 ℃, most of the Ni is oxidized to Ni O phase, and tolerated 50 h of oxidation and finally cracked and spalled from the specimen. YSZ（Ni：Al=1：3） and YSZ（Ni：Al=1：2） coated samples show superior oxidation resistance than that of YSZ coating. The different oxidation resistance mechanisms of YSZ/（Ni, Al） composite coatings sintered in CH_4 atmosphere were discussed.

关键词： EPD composite coatings oxidation resistance phase transformation