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Open Journal of Optimization 2014年第4期3卷 68-78页

作者： Sana Iftekhar qazi mazhar ali Mohammad Jameel Ahsan Department of Statistics & Operations Research Aligarh Muslim University Aligarh India

This paper is an attempt to work out a compromise allocation to construct combined ratio estimates under multivariate double sampling design in presence of non-response when the population mean of the auxiliary variable is unknown. The problem has been formulated as a multi-objective integer non-linear programming problem. Two solution procedures are developed using goal programming and fuzzy programming techniques. A numerical example is also worked out to illustrate the computational details. A comparison of the two methods is also carried out.

关键词： Multivariate Stratified Sampling Compromise Allocation Non-Response Double Sampling Goal Programming Fuzzy Programming

Identification of Software Bugs by Analyzing Natural Language-Based Requirements Using Optimized Deep Learning Features

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Computers, Materials & Continua 2024年第3期78卷 4379-4397页

作者： qazi mazhar ul Haq Fahim Arif Khursheed Aurangzeb Noor ul Ain Javed ali Khan Saddaf Rubab Muhammad Shahid Anwar Department of Computer Science and Engineering and International Bachelor’s Program in Informatics Yuan Ze UniversityZhongliTaoyuan320315Taiwan Department of Computer Science National University of PakistanRawalpindiPunjab46000Pakistan Department of Computer Software Engineering MCSNational University of Sciences and TechnologyIslamabad44000Pakistan Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Saudi Arabia Department of Computer Science School of PhysicsEngineering and Computer ScienceUniversity of HertfordshireHatfieldAL109ABUK Department of Computer Engineering College of Computing and InformaticsUniversity of SharjahSharjah27272United Arab Emirates Department of AI and Software Gachon UniversitySeongnam-SI13120South Korea

Software project outcomes heavily depend on natural language requirements,often causing diverse interpretations and issues like ambiguities and incomplete or faulty *** are exploring machine learning to predict software bugs,but a more precise and general approach is *** bug prediction is crucial for software evolution and user training,prompting an investigation into deep and ensemble learning ***,these studies are not generalized and efficient when extended to other ***,this paper proposed a hybrid approach combining multiple techniques to explore their effectiveness on bug identification *** methods involved feature selection,which is used to reduce the dimensionality and redundancy of features and select only the relevant ones;transfer learning is used to train and test the model on different datasets to analyze how much of the learning is passed to other datasets,and ensemble method is utilized to explore the increase in performance upon combining multiple classifiers in a *** National Aeronautics and Space Administration(NASA)and four Promise datasets are used in the study,showing an increase in the model’s performance by providing better Area Under the Receiver Operating Characteristic Curve(AUC-ROC)values when different classifiers were *** reveals that using an amalgam of techniques such as those used in this study,feature selection,transfer learning,and ensemble methods prove helpful in optimizing the software bug prediction models and providing high-performing,useful end mode.

关键词： Natural language processing software bug prediction transfer learning ensemble learning feature selection

Metabolic puzzle: Exploring liver fibrosis differences in Asian metabolic-associated fatty liver disease subtypes

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World Journal of Hepatology 2024年第1期16卷 54-64页

作者： Sabhita Shabir Shaikh Fakhar ali qazi-Arisar Saba Nafay Sidra Zaheer Hafeezullah Shaikh Zahid Azam National Institute of Liver and GI Diseases Dow University of Health SciencesSindhKarachi 75330Pakistan School of Public Health Dow University of Health SciencesSindhKarachi 75330Pakistan

BACKGROUND Metabolic-associated fatty liver disease(MAFLD)is a liver condition marked by excessive fat buildup in the absence of heavy alcohol *** is primarily linked with metabolic issues like insulin resistance,obesity,and abnormal lipid levels,and is often observed with other conditions such as type 2 diabetes and cardiovascular ***,whether the subtypes of MAFLD based on the metabolic disorder differentially impact liver fibrosis is not well explicated,especially in the Asian *** To compare the severity of liver fibrosis among different MAFLD *** A total of 322 adult patients of either gender with fatty liver on ultrasound were enrolled between January to December *** was defined as per the Asian Pacific Association for the Study of the Liver ***-4 index(Fib-4)and nonalcoholic fatty liver disease fibrosis score(NFS)were employed to evaluate liver *** The mean age was 44.84±11 ***-two percent of the patients were *** hundred and seventy-three patients were classified as having MAFLD,of which 110(40.3%)carried a single,129(47.3%)had two,and 34(12.5%)had all three metabolic *** cumulative number of metabolic conditions was related to elevated body mass index,triglyceride(TG)levels,and glycated hemoglobin,lower high-density lipoprotein(HDL)levels,higher liver inflammation(by aspartate aminotransferase andγ-glutamyl transferase),and higher likelihood of fibrosis(by NFS and Fib-4 scores)(P<0.05 for all).The proportion of advanced fibrosis also increased with an increase in the number of metabolic conditions(4.1%,25.5%,35.6%,and 44.1%by NFS and 6.1%,10.9%,17%,and 26.5%by Fib-4 for no MAFLD and MAFLD with 1,2,and 3 conditions,respectively).Among MAFLD patients,those with diabetes alone were the eldest and had the highest mean value of NFS score and Fib-4 score(P<0.05),while MAFLD patients diagnosed with lean metabolic dysfunction exhibited the highest levels of TG and a

关键词： Metabolic syndrome Diabetes Fatty liver disease Dyslipidemia Obesity

Risk factors and outcomes of peptic ulcer bleed in a Pakistani population:A single-center observational study

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2024年第3期15卷 1-9页

作者： Nazish Butt Muhammad Tayyab Usmani Nimrah Mehak Saba Mughal Fakhar ali qazi-Arisar Ghulam Mohiuddin Gulzar Khan Department of Gastroenterology Jinnah Postgraduate Medical CentreKarachi 75505SindhPakistan National Institute of Liver&GI Diseases Dow University of Health SciencesKarachi 75330SindhPakistan School of Public Health Dow University of Health SciencesKarachi 75330SindhPakistan

BACKGROUND Peptic ulcer disease(PUD)remains a significant healthcare burden,contributing to morbidity and mortality *** advancements in therapies,its prevalence persists,particularly in regions with widespread nonsteroidal antiinflammatory drugs(NSAIDs)use and Helicobacter pylori *** To comprehensively analyse the risk factors and outcomes of PUD-related upper gastrointestinal(GI)bleeding in Pakistani *** This retrospective cohort study included 142 patients with peptic ulcer bleeding who underwent upper GI endoscopy from January to December *** on demographics,symptoms,length of stay,mortality,re-bleed,and Forrest classification was *** The mean age of patients was 53 years,and the majority was men(68.3%).Hematemesis(82.4%)and epigastric pain(75.4%)were the most common presenting *** patients(73.2%)were discharged within five *** mortality rates at one week and one month were 10.6%and 14.8%,***-bleed within 24 h and seven days occurred in 14.1%and 18.3%of patients,*** ulcers were Forrest class(FC)Ⅲ(72.5%).Antiplatelet use was associated with higher mortality at 7 and 30 d,while alternative medications were linked to higher 24-hour re-bleed *** use was associated with more FCⅢ***-bleed at 24 h and 7 d was strongly associated with one-week or one-month *** Antiplatelet use and rebleeding increase the risk of early mortality in PUD-related upper GI bleeding,while alternative medicines are associated with early rebleeding.

关键词： Non variceal bleed Mortality Re-bleed Forrest classification Antiplatelets Alternative medicines

Unraveling the therapeutic mechanisms of myristic acid and luteolin 7-rutinoside in oral cancer: insights from network pharmacology and molecular docking analysis

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Pharmacology Discovery 2024年第2期4卷 1-9页

作者： Ansari Vikhar Danish Ahmad Misba Ruhi Syed Ayaz ali qazi Yasar Mohd.Mukhtar Khan Subur W Khan Mohammed Imran Anees Y.B.Chavan College of Pharmacy Dr.Babasaheb Ambedkar Marathwada UniversityAurangabad 431001India Maulana Azad College Dr.Babasaheb Ambedkar Marathwada UniversityAurangabad 431001India

Background:The compound Luteolin-7-rutinoside(L7R)is a flavone derivative of luteolin,predominantly identified in plant species belonging to the families ***,Myristic acid is characterized by its structure as a 14-carbon,unsaturated fatty *** this investigation,we endeavor to elucidate the putative mechanisms underlying the therapeutic effects of Myristic Acid and Luteolin 7-rutinoside in the context of oral cancer treatment,employing network pharmacology coupled with molecular docking ***:The protein targets of Myristic Acid and Luteolin 7-rutinoside were identified through a search on the Swiss Target ***,a compound-target network was constructed using Cytoscape *** associated with OC were retrieved from the OMIM and GeneCards *** overlap between compound targets and OC-related targets was determined,and the resulting shared targets were subjected to protein-protein interaction(PPI)network analysis using the STRING ***,gene ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses were conducted on the identified *** docking were performed to investigate the interactions between the core target and the active ***:The component target network comprises 103 nodes and 102 *** the proteins in the protein-protein interaction(PPI)network,those with higher degrees are TNF,PPARG,and *** through Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathways indicates that the treatment of OC with Myristic Acid and Luteolin 7-rutinoside primarily involves the regulation of miRNA transcription and inflammatory *** identified signaling pathways include Pathways in cancer,PPAR signaling pathway,EGFR signaling pathway,and TNF signaling *** docking studies reveal that Luteolin 7-rutinoside and Myristic acid exhibit higher affinity towards TNF,PPARG,TP53,and ***:This study

关键词： myristic acid luteolin 7-rutinoside network pharmacology oral cancer molecular docking

Removal of heavy metals through adsorption using sand

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Journal of Environmental Sciences 2003年第3期15卷 413-416页

作者： M. ali Awan Ishtiaq A. qazi Imran Khalid Institute of Environmental Science and Engineering (IESE) National University of Sciences & Technology (NUST) Rawalpindi PakistanPakistan Council of Renewable Energy TechnologiesInstitute of Environmental Science and Engineering (IESE) National University of Sciences & Technology (NUST) Rawalpindi Pakistan Islamabad Pakistan

The removal of four heavy metals i.e. Pb, Cr, Cu, and Zn from their aqueous solutions, using ordinary sand as an adsorbent, was studied at 20℃. The amount of metal adsorbed to form monolayer on sand(a_m), obtained from Langmuir isotherm, exhibited the preference of metals for sand in the order Pb>Cr>Cu>Zn. The heavy metal-sand adsorption phenomena can be illustrated on the basis of the interaction between surface functional group of silicates (sand) and the metal ions. It is deduced that sand can be used as a low cost adsorbent for the removal of heavy metal from wastewater (containing low conc. of metals), especially in the developing countries.

关键词： sand heavy metals adsorption

An interacting scenario for dark energy in a Bianchi type-I universe

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Research in Astronomy and Astrophysics 2014年第11期14卷 1383-1392页

作者： Hassan Amirhashchi Syed Nasrullah ali qazi Hishamuddin Zainuddin Department of Physics Mahshahr Branch Islamic Azad University Laboratory of Computational Sciences and Mathematical Physics Institute for Mathematical Research Universiti Putra Malaysia

We study the interaction between dark energy （DE） and dark matter in the scope of anisotropic Bianchi type-I space-time. First we derive the general form of the DE equation of state （EoS） parameter in both non-interacting and interacting cases and then we examine its future by applying a hyperbolic scale factor. It is shown that in the non-interacting case, depending on the value of the anisotropy parameter K, the DE EoS parameter varies from phantom to quintessence whereas in the interacting case the EoS parameter varies in the quintessence region. However, in both cases, the DE EoS parameter ωde ultimately （i.e. at z ： -1） tends to the cosmological constant （ωde = -1）. Moreover, we fix the cosmological bound on the anisotropy parameter K by using recent observational data about the Hubble parameter.

关键词： cosmology: Bianchi type-I model -- dark energy -- dark matter

Development of thermochromic strips as a water pasteurization indicator

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Journal of Environmental Sciences 2003年第6期15卷 863-864页

作者： Ishtiaq A. qazi M. ali Awan M. Anwar Baig Pakistan Council of Renewable Energy Technologies(PCRET) Institute of Environmental Science and Engineering(IESE) National University of Sciences & Technology (NUST)Institute of Environmental Science and Engineering(IESE) National University of Sciences & Technology (NUST) Islamabad PakistanRawalpindi PakistanRawalpindi Pakistan

Boiling of water, for purification, commonly practiced in the world, has many problems associated with it like danger of scalding, scaling in the vessels, removal of useful minerals and blandness of taste etc. Water can be made safe for drinking simply by heating at 65℃ for 6 minutes. A colour indicating strip was developed which changes colour from red to purple at 67℃. Use of this strip can help in pasteurizing water without the above problems and with considerable energy saving.

关键词： thermochromic strips pasteurization indicator Pakistan

Wolbachia-infected mosquitoes:The answer to the dengue endemic in Pakistan?

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Asian Pacific Journal of Tropical Medicine 2021年第9期14卷 383-384页

作者： qazi Syed Muhammad ali Mustafa Ashiq Husain Department of Internal Medicine Dow University of Health SciencesKarachiPakistan Department of Internal Medicine Ziauddin UniversityKarachiPakistan

Dengue is an infectious disease of viral etiology characterized by acute flu-like symptoms with potentially lethal *** virus is transmitted by the mosquitoes of the Aedes genus^([1]).These mosquitoes dwell around smal... 详细信息

关键词： acute infected mosquitoes

Effect of Salicylic Acid on Salinity-induced Changes in Brassica juncea

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Journal of Integrative Plant Biology 2008年第9期50卷 1096-1102页

作者： Mohammad Yusuf Syed Aiman Hasan Barket ali Shamsul Hayat qazi Fariduddin Aqil Ahmad Plant Physiology Section Department of Botany Aligarh Muslim University Department of Applied Sciences Higher College of Technology

Seeds of Indian mustard （Brassicajuncea （L.） Czern. et Coss.） were exposed to 0, 50, 100 and 150 mmol/L NaCI for 8 h and seeds were sown in an earthen pot. These stressed seedlings were subsequently sprayed with 10μmol/L salicylic acid （SA） at 30 d and were sampled at 60 d to assess the changes in growth, photosynthesis and antioxidant enzymes. The seedlings raised from the seeds treated with NaCI had significantly reduced growth and the activities of carbonic anhydrase, nitrate reductase and photosynthesis, and the decrease was proportional to the increase in NaCI concentration. However, the antioxidant enzymes （catalase, peroxidase and superoxide dismutase） and proline content was enhanced in response to NaCI and/or SA treatment, where their interaction had an additive effect. Moreover, the toxic effects generated by the lower concentration of NaCI （50 mmol/L） were completely overcome by the application of SA. It was, therefore, concluded that SA ameliorated the stress generated by NaCl through the alleviated antioxidant system.

关键词： carbonic anhydrase catalase mustard net photosynthetic rate nitrate reductase peroxidase salicylic acid salinity superoxidedismutase.